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The map label for this gene is prlA [H]

Identifier: 126697660

GI number: 126697660

Start: 111943

End: 113211

Strand: Direct

Name: prlA [H]

Synonym: CD0090

Alternate gene names: 126697660

Gene position: 111943-113211 (Clockwise)

Preceding gene: 126697659

Following gene: 126697661

Centisome position: 2.61

GC content: 32.07

Gene sequence:

>1269_bases
GTGCTGTCAAAATTAAAACAAGCTTGGAAGATTAAAGCAGTAAGAAAAAAAGTAATGTATACACTTATGATGATCGTGAT
ATTCAGAATAGGTACTACTATACCAGTTCCAGGCATAGACACTAGTATTATACAAAAGATGGTAGGCGGCAATAGTCTAC
TTTCTCTGTATAATATGTTTACTGGTGGAGCATTTAGTAACTTTTCACTATTTGCTTTAGGTATAAGTCCATATATCACT
GCATCAATCATAATACAACTTCTAACAGTAGGTTTTGAAAGTTTAGCAGAACTTCAAAAATCTGGTGAAGAAGGAAAGAA
AAAAATCAATAAGTACACTAAATATACAGCACTAGCTCTAGCAGTTGTACAAGCTTTGGGAATTACATTAGGAATTGTAA
GAAGTGCTTTAATATCAAATAGTGTGTTTTTTATCACAACTGTTGTAATAACATTAGTTTCAGCAAGTATGTTAGTAATG
TGGATTGGGGACAAAATTACTGAAAAAGGAATCGGTAATGGTAGTTCAGTAATAATATTTGCAGGTATAATATCAAGAAT
ACCTACAGATGTTATTAAAATATCGCAACAAGTTAAATCTGGCGAAGTTGCACCTTGGGTTATAGTGATTCTAGCTGTAG
TTATATTACTTACAGTAACAGGAGTTACATTTATACAAGAAGCAACTAGAAAGATACCTGTACAATATGCTAAAAGAGTT
GTTGGAAGAAAAATGTATGGAGGACAAAGTTCTCATATACCAATGAAAGTTAACCAGTCAGGAGTTATGCCTATAATTTT
TGCTAGTTCACTTTTAGCTTTCCCTCAAACAATAGCTATGTTTATGGGTCCAAATGCTCAGGCTTTTGTTCAAAAATACT
TAAGTATGGCAACAGAACAAGGATTTTGGACATATAGATCAATTGAGATTCTACTTATAATTTTCTTCTCATATTTTTAT
ACAACTGTATCATTTAATACAGAAGACATATCTAAAAATATGAAAAATAATGGTGGATTTATACCAGGTATAAGACCAGG
TGAGCCTACTATGGATTATTTAAATAGAATTTTAACTAGATTAACTTTAGCTGGAGCTACTTTCTTAGCAATAATTGCTA
TGGTGCCAGCTCTTACAACACATTATATGAAAGTAAATATGAGTCTAGCTGGGACTTCATTGCTAATCGTTGTTGGAGTT
GCTTTGGAGCTTAAGAGACAGTTAGAGTCAAACTTAGTTATGAGAAGCTATCAAGGTTTCTTAAAATAA

Upstream 100 bases:

>100_bases
ACAGCTTCAGCTCAAGAAAAAATAGAAAAAGCTGGTGGAAAAGCAGAGTTAGTATAATAACCTGCTAATCTCCTAGCCAG
TACAGGCGGGGTGAATTAGC

Downstream 100 bases:

>100_bases
AATGGAGATGGATAATATGAGAATAATATTACTTGGACCTCCAGGTGCTGGTAAAGGTACTCAGGCGGTAGGAATAGTAG
AAAAATACAATATACCTCAT

Product: preprotein translocase SecY subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSIIQKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYIT
ASIIIQLLTVGFESLAELQKSGEEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLTVTGVTFIQEATRKIPVQYAKRV
VGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQTIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFY
TTVSFNTEDISKNMKNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGTSLLIVVGV
ALELKRQLESNLVMRSYQGFLK

Sequences:

>Translated_422_residues
MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSIIQKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYIT
ASIIIQLLTVGFESLAELQKSGEEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLTVTGVTFIQEATRKIPVQYAKRV
VGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQTIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFY
TTVSFNTEDISKNMKNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGTSLLIVVGV
ALELKRQLESNLVMRSYQGFLK
>Mature_422_residues
MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSIIQKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYIT
ASIIIQLLTVGFESLAELQKSGEEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLTVTGVTFIQEATRKIPVQYAKRV
VGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQTIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFY
TTVSFNTEDISKNMKNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGTSLLIVVGV
ALELKRQLESNLVMRSYQGFLK

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=416, Percent_Identity=41.3461538461538, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 46242; Mature: 46242

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSIIQKMVGGNSLLSLYNMF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
TGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSGEEGKKKINKYTKYTALAL
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVMWIGDKITEKGIGNGSSVIIF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHH
AGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLTVTGVTFIQEATRKIPVQYAKRV
HHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQTIAMFMGPNAQAFVQKYLSMATEQ
HHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNMKNNGGFIPGIRPGEPTMDYLNRILTR
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LTLAGATFLAIIAMVPALTTHYMKVNMSLAGTSLLIVVGVALELKRQLESNLVMRSYQGF
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LK
CC
>Mature Secondary Structure
MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSIIQKMVGGNSLLSLYNMF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
TGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSGEEGKKKINKYTKYTALAL
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVMWIGDKITEKGIGNGSSVIIF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHH
AGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLTVTGVTFIQEATRKIPVQYAKRV
HHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQTIAMFMGPNAQAFVQKYLSMATEQ
HHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNMKNNGGFIPGIRPGEPTMDYLNRILTR
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LTLAGATFLAIIAMVPALTTHYMKVNMSLAGTSLLIVVGVALELKRQLESNLVMRSYQGF
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA