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The map label for this gene is rpoB

Identifier: 126697633

GI number: 126697633

Start: 90160

End: 93876

Strand: Direct

Name: rpoB

Synonym: CD0066

Alternate gene names: 126697633

Gene position: 90160-93876 (Clockwise)

Preceding gene: 126697632

Following gene: 126697634

Centisome position: 2.1

GC content: 33.33

Gene sequence:

>3717_bases
ATGCCACATCCTGTCACGATAGGTAAAAGAACTAGAATGAGCTTTTCTAAAATTAAGGAAATAGCTGATGTGCCAAATCT
TATAGAAATTCAAGTAGATTCCTATGAGTGGTTTTTAAAAGAAGGTTTAAAAGAAGTGTTTGATGATATTTCACCAATAG
AAGATTATACTGGTAATCTTATATTGGAATTTGTCGACTATTCTCTAGATGATAAACCAAAGTACGATATAGAAGAGTGT
AAAGAGAGAGATGCTACATATTGTGCACCTCTAAAGGTTAAGGTAAGACTTATAAATAAAGAAACAGGTGAGATAAAAGA
ACAAGAAGTGTTTATGGGTGACTTCCCTTTAATGACAGAAAGAGGAACTTTCGTTATAAATGGAGCAGAAAGAGTTATAG
TAAGTCAATTAGTTAGATCTCCTGGTGTTTACTATGCGGAAGAAAGAGATAAAACAGGTAAGAGATTGATTTCATCTACT
GTAATTCCTAATAGAGGAGCATGGTTAGAATATGAAACAGATTCTAATGATGTAATATCTGTAAGAGTTGATAGAACAAG
AAAACAACCAGTTACAGTTTTACTTAGAGCTTTAGGAATAGGAACAGATGCAGAGATAATTGACCTTTTAGGAGAAGATG
AGAGATTATCTGCTACATTAGAAAAAGATAATACTAAGACAGTAGAAGAAGGTCTTGTAGAGATATACAAAAAATTAAGA
CCAGGTGAACCTCCTACTGTAGAAAGTGCATCATCTTTATTAAATGCTTTATTCTTTGACCCAAAAAGATATGACCTAGC
AAAAGTTGGTAGATATAAATTCAATAAGAAACTTGCTTTATGTTATAGAATAATGAATAAAATTTCAGCAGAAGACATAA
TAAATCCAGAAACTGGAGAAGTATTTGTAAAAGCTGGAGAAAAAATAAGCTATGATTTGGCTAAAGCCATACAAAATGCA
GGTATAAATGTAGTAAATCTACTAATGGATGATGATAAAAAAGTTAGAGTTATAGGAAATAATTTTGTGGATATTAAGTC
TCACATTGATTTTGACATAGATGATTTAAACATAAAAGAAAAAGTACATTATCCAACTTTAAAAGAAATTTTAGATGGAT
ATAGTGATGAAGAAGAAATAAAAGAGGCTATAAAATCAAGAATTAAAGAACTTATACCAAAACATATATTATTAGATGAT
ATAATAGCTTCAATAAGTTATGAGTTCAATATATTCTATAATATAGGAAATATTGATGATATAGATCACCTAGGAAACAG
AAGAATAAGATCTGTAGGTGAATTGTTACAAAATCAAGTTAGAATTGGTCTTTCAAGAATGGAAAGAGTTATAAAAGAAA
GAATGACGGTTCAAGATATGGAAGCTATAACGCCTCAAGCGTTAGTTAACATAAGACCAGTTTCAGCTGCAATAAAAGAA
TTTTTTGGTAGTTCTCAGTTATCTCAGTTCATGGATCAAACAAATCCTCTATCTGAGTTAACGCATAAGAGAAGATTATC
AGCCCTTGGGCCTGGAGGTCTTTCAAGAGAAAGAGCTGGATTCGAAGTGCGTGACGTTCACCATTCACACTATGGTAGAA
TGTGTCCAATAGAGACTCCAGAGGGACCAAATATCGGTCTTATAAACTCTCTAGGAACTTATGCAAAAATAAATGAATTT
GGATTTATAGAATCACCATATAGAAAATTTGATAAAGAAACATCAACAGTTACTGATGAAATACATTATTTAACTGCTGA
CGAAGAAGATTTATTCGTAAGAGCTCAGGCAAATGAGCCATTAACAGAAGATGGTAAATTCGTAAACCATAGAGTTGTTT
GTAGAACTGTAAATGGTGCTGTTGAAATGGTTCCTGAAAGTAGAGTAGATTACATGGATATATCTCCTAAGCAGGTTGTA
TCTGTTGCCACTGCTATGATACCTTTCTTAGAAAATGATGATGCCAACCGTGCCCTTATGGGAGCGAACATGCAGCGTCA
GGCAGTGCCTCTAGTTAGAAGAGAAGCACCAATTATAGGAACTGGTATAGAATACAGAGCAGCAAAAGACTCTGGAGCAG
TTGTTGTTGCTAGAAATTCTGGTATAGCAGAAAGAGTAACAGCAGATGAAATAATTATAAAAAGAGAAGATGGAAACAGA
GATAGATATAATCTACTTAAGTTTAAACGTTCAAACTCAGGTACTTGTATAAATCAAACACCTATAATAAATAAGGGTGA
CCAGATAATAAAAGGTGATGTTATAGCAGATGGTCCAGCAACTGATTTAGGAGAAGTTGCACTTGGAAGAAACTGTCTTA
TAGCATTCATGACTTGGGAAGGTTATAACTACGAGGATGCTATATTAATAAATGAAAGATTAGTTAAAGAAGATAGATTA
TCAACAATTCATATAGAAGAATATGAATGTGAAGCTAGAGATACAAAACTAGGGCCAGAGGAAATAACTAGAGATATACC
TAATGTTGGAGATAGTGCAATTAAGAACTTAGATGACAGAGGTATAATAAGAATAGGTGCAGAAGTAGACTCAGGTGATA
TATTAGTTGGTAAAGTAACTCCAAAAGGAGAAACTGAACTTACTGCTGAGGAAAGATTACTTCGTGCAATATTTGGAGAA
AAGGCTAGAGAAGTTAGAGATACTTCACTTAAAGTGCCTCATGGTGAATCTGGTATAATAGTTGATGTAAAAGTATTTAC
TAGAGAAAATGGAGATGATTTATCTCCAGGAGTAAATGAATTAGTAAGATGCTATATAGCTAAAAAGAGAAAAATAAAAG
TTGGAGATAAAATGGCTGGTCGTCATGGTAATAAAGGGGTTATCTCAAGAGTATTACCTGAAGAAGATATGCCATTCATG
GAAAATGGAACACCACTAGACATAATACTTAACCCACAAGGTATACCATCACGTATGAACATTGGTCAGGTTTTAGAAGT
TCATTTAGGACTTGCTGCTAAGACATTAGGATGGTATGTAGCAACATCAGTATTCGATGGTGCTAATGAGTATGACATAA
TGGATGCTCTTGAAGAAGCTGGGTATCCTAGAGATGGTAAATTAACTTTATATGATGGTAGAACAGGTGAGTCTTTTGAC
AACAGAATAACTGTTGGATATATGTACTACTTGAAACTACATCACTTAGTAGATGAAAAACTACATGCAAGAAGTACTGG
ACCATACTCATTAGTTACTCAACAGCCACTAGGTGGTAAAGCACAATTTGGTGGACAAAGATTTGGAGAGATGGAGGTTT
GGGCTCTGGAAGCATATGGAGCTGCTCACATACTTCAAGAAATACTTACTGTTAAGTCTGATGACGTTGTAGGTCGTGTT
AGAACATATGAAGCTATAGTTAAAGGTGAAAATATACCTGAACCAGGAATCCCAGAATCATTTAAGGTTCTTATAAAAGA
ACTTCAAAGTTTATGCTTAGATGTAAAAGTATTGACAGATGAAGACCAAGAAATAGAAGTAAGAGAATCTGTGGATGAAG
ATGATACAATAGGTGAATTTGAGCTAGATGTTGTAAATCATATGGGAGAAGTTGAAGAAAGTAATATAATAGAAGAAATT
GAAGATGATTTTGCAGAAAATGCAGAAGATGAGGATATAGAGAATTTAGAAGAATTCACTGAAGATGATTTATTTGAAGA
AGAAATAGATTTTGATAGTGATGACTTTGATATGTAA

Upstream 100 bases:

>100_bases
TAAAAAATATATTGAAAAATACTTGACATTATGCTAAAATTATTAGATGCGTTAGAATGAACTATTGTTTTATTTTTAAT
TATTGAGAGGTGAAAAGTGA

Downstream 100 bases:

>100_bases
ATTTAATTAATGTAAATCTCAAATAGAAGGGAGAGAACTCCTTGTTTGAATTAAACAATTTCGAGTCGATAAAAATAGCA
TTGGCTTCTCCAGAAAAAAT

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1238; Mature: 1237

Protein sequence:

>1238_residues
MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLKEVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEEC
KERDATYCAPLKVKVRLINKETGEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSATLEKDNTKTVEEGLVEIYKKLR
PGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNKKLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNA
GINVVNLLMDDDKKVRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELIPKHILLDD
IIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERVIKERMTVQDMEAITPQALVNIRPVSAAIKE
FFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEF
GFIESPYRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMVPESRVDYMDISPKQVV
SVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTGIEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNR
DRYNLLKFKRSNSGTCINQTPIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKEDRL
STIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILVGKVTPKGETELTAEERLLRAIFGE
KAREVRDTSLKVPHGESGIIVDVKVFTRENGDDLSPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFM
ENGTPLDIILNPQGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTLYDGRTGESFD
NRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHILQEILTVKSDDVVGRV
RTYEAIVKGENIPEPGIPESFKVLIKELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEI
EDDFAENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM

Sequences:

>Translated_1238_residues
MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLKEVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEEC
KERDATYCAPLKVKVRLINKETGEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSATLEKDNTKTVEEGLVEIYKKLR
PGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNKKLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNA
GINVVNLLMDDDKKVRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELIPKHILLDD
IIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERVIKERMTVQDMEAITPQALVNIRPVSAAIKE
FFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEF
GFIESPYRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMVPESRVDYMDISPKQVV
SVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTGIEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNR
DRYNLLKFKRSNSGTCINQTPIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKEDRL
STIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILVGKVTPKGETELTAEERLLRAIFGE
KAREVRDTSLKVPHGESGIIVDVKVFTRENGDDLSPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFM
ENGTPLDIILNPQGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTLYDGRTGESFD
NRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHILQEILTVKSDDVVGRV
RTYEAIVKGENIPEPGIPESFKVLIKELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEI
EDDFAENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM
>Mature_1237_residues
PHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLKEVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECK
ERDATYCAPLKVKVRLINKETGEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISSTV
IPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSATLEKDNTKTVEEGLVEIYKKLRP
GEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNKKLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAG
INVVNLLMDDDKKVRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELIPKHILLDDI
IASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERVIKERMTVQDMEAITPQALVNIRPVSAAIKEF
FGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFG
FIESPYRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMVPESRVDYMDISPKQVVS
VATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTGIEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRD
RYNLLKFKRSNSGTCINQTPIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKEDRLS
TIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILVGKVTPKGETELTAEERLLRAIFGEK
AREVRDTSLKVPHGESGIIVDVKVFTRENGDDLSPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFME
NGTPLDIILNPQGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTLYDGRTGESFDN
RITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHILQEILTVKSDDVVGRVR
TYEAIVKGENIPEPGIPESFKVLIKELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIE
DDFAENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI4505941, Length=419, Percent_Identity=31.5035799522673, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI238908503, Length=409, Percent_Identity=31.2958435207824, Blast_Score=181, Evalue=5e-45,
Organism=Homo sapiens, GI238908505, Length=409, Percent_Identity=31.2958435207824, Blast_Score=181, Evalue=5e-45,
Organism=Homo sapiens, GI33469941, Length=428, Percent_Identity=28.7383177570093, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI212286172, Length=428, Percent_Identity=28.7383177570093, Blast_Score=164, Evalue=5e-40,
Organism=Escherichia coli, GI1790419, Length=956, Percent_Identity=48.5355648535565, Blast_Score=848, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=412, Percent_Identity=31.7961165048544, Blast_Score=183, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17552304, Length=425, Percent_Identity=30.8235294117647, Blast_Score=182, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI17506623, Length=210, Percent_Identity=39.5238095238095, Blast_Score=140, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6324725, Length=423, Percent_Identity=30.4964539007092, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324781, Length=417, Percent_Identity=29.2565947242206, Blast_Score=177, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6325267, Length=361, Percent_Identity=32.9639889196676, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17136444, Length=419, Percent_Identity=29.1169451073986, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17647877, Length=410, Percent_Identity=29.7560975609756, Blast_Score=176, Evalue=9e-44,
Organism=Drosophila melanogaster, GI17136446, Length=800, Percent_Identity=25.25, Blast_Score=152, Evalue=2e-36,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_CLOD6 (Q18CF1)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001086530.1
- ProteinModelPortal:   Q18CF1
- STRING:   Q18CF1
- GeneID:   4914216
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD0066
- NMPDR:   fig|1496.1.peg.3127
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- ProtClustDB:   PRK00405
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 139324; Mature: 139193

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLKEVFDDISPIEDYTGNL
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCHHHHCCCE
ILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKETGEIKEQEVFMGDFPLMTE
EEEECCCCCCCCCCCCHHHHHCCCCCEECCEEEEEEEECCCCCCCCHHHEEECCCCEEEC
RGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISSTVIPNRGAWLEYETDSNDVIS
CCCEEECCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEE
VRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSATLEKDNTKTVEEGLVEIYKKLR
EEECCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHHHHHHC
PGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNKKLALCYRIMNKISAEDIINPETGE
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCHHHCCCCCCCE
VFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKKVRVIGNNFVDIKSHIDFDIDDLNIKE
EEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCEEEEHHCCCCCCCCCCCHH
KVHYPTLKEILDGYSDEEEIKEAIKSRIKELIPKHILLDDIIASISYEFNIFYNIGNIDD
HCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCC
IDHLGNRRIRSVGELLQNQVRIGLSRMERVIKERMTVQDMEAITPQALVNIRPVSAAIKE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECHHHHHHHH
FFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETP
HHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
EGPNIGLINSLGTYAKINEFGFIESPYRKFDKETSTVTDEIHYLTADEEDLFVRAQANEP
CCCCEEEECCCCCHHHHHCCCCCCCHHHHHCCHHHHHHHHEEEEECCCCCEEEEECCCCC
LTEDGKFVNHRVVCRTVNGAVEMVPESRVDYMDISPKQVVSVATAMIPFLENDDANRALM
CCCCCCCCCCEEEEEEECCHHEECCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCEEE
GANMQRQAVPLVRREAPIIGTGIEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNR
CCCCHHHHCCHHHHCCCEEECCCEEEECCCCCCEEEEECCCCHHHCCCCEEEEECCCCCC
DRYNLLKFKRSNSGTCINQTPIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWE
CHHHHEEEECCCCCCEECCCCCCCCCCCEEECCEECCCCCCCHHHHHCCCCEEEEEEEEC
GYNYEDAILINERLVKEDRLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDR
CCCCCCEEEEHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCC
GIIRIGAEVDSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGII
CEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEE
VDVKVFTRENGDDLSPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFM
EEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEECCCHHCCCCCCCHHHHHHCCCCCCCCC
ENGTPLDIILNPQGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEA
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHC
GYPRDGKLTLYDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGK
CCCCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
AQFGGQRFGEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPES
CCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHH
FKVLIKELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEI
HHHHHHHHHHHHEEEEEECCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHH
EDDFAENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLKEVFDDISPIEDYTGNL
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCHHHHCCCE
ILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKETGEIKEQEVFMGDFPLMTE
EEEECCCCCCCCCCCCHHHHHCCCCCEECCEEEEEEEECCCCCCCCHHHEEECCCCEEEC
RGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISSTVIPNRGAWLEYETDSNDVIS
CCCEEECCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEE
VRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSATLEKDNTKTVEEGLVEIYKKLR
EEECCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHHHHHHC
PGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNKKLALCYRIMNKISAEDIINPETGE
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCHHHCCCCCCCE
VFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKKVRVIGNNFVDIKSHIDFDIDDLNIKE
EEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCEEEEHHCCCCCCCCCCCHH
KVHYPTLKEILDGYSDEEEIKEAIKSRIKELIPKHILLDDIIASISYEFNIFYNIGNIDD
HCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCC
IDHLGNRRIRSVGELLQNQVRIGLSRMERVIKERMTVQDMEAITPQALVNIRPVSAAIKE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECHHHHHHHH
FFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETP
HHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
EGPNIGLINSLGTYAKINEFGFIESPYRKFDKETSTVTDEIHYLTADEEDLFVRAQANEP
CCCCEEEECCCCCHHHHHCCCCCCCHHHHHCCHHHHHHHHEEEEECCCCCEEEEECCCCC
LTEDGKFVNHRVVCRTVNGAVEMVPESRVDYMDISPKQVVSVATAMIPFLENDDANRALM
CCCCCCCCCCEEEEEEECCHHEECCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCEEE
GANMQRQAVPLVRREAPIIGTGIEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNR
CCCCHHHHCCHHHHCCCEEECCCEEEECCCCCCEEEEECCCCHHHCCCCEEEEECCCCCC
DRYNLLKFKRSNSGTCINQTPIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWE
CHHHHEEEECCCCCCEECCCCCCCCCCCEEECCEECCCCCCCHHHHHCCCCEEEEEEEEC
GYNYEDAILINERLVKEDRLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDR
CCCCCCEEEEHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCC
GIIRIGAEVDSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGII
CEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEE
VDVKVFTRENGDDLSPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFM
EEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEECCCHHCCCCCCCHHHHHHCCCCCCCCC
ENGTPLDIILNPQGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEA
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHC
GYPRDGKLTLYDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGK
CCCCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
AQFGGQRFGEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPES
CCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHH
FKVLIKELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEI
HHHHHHHHHHHHEEEEEECCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHH
EDDFAENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA