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The map label for this gene is sigH [H]

Identifier: 126697623

GI number: 126697623

Start: 82988

End: 83650

Strand: Direct

Name: sigH [H]

Synonym: CD0057

Alternate gene names: 126697623

Gene position: 82988-83650 (Clockwise)

Preceding gene: 126697622

Following gene: 126697624

Centisome position: 1.93

GC content: 29.26

Gene sequence:

>663_bases
ATGGGGGAGATTTACATGTTGGTAGCAAAAGAAAAAAGTTATGAGTTAGTGGACAATTGTCAGCAGGATGAGTATAACAT
TGTATTAAGAGCAAGTGAAGGGGATAAAATAGCACTAGAGTACATTATTACTAAATACAGAAATTTTGTAAAGGCAAAAG
CAAAGTCATATTTTTTAATTGGAGCAGATAAAGAAGATATAATACAAGAAGGAATGATAGGCCTTTATAAGGCAGTTAGA
GATTTTGATGGAAGTAAGACCAATTCATTTAAATGTTTTGCGGAGATATGTATAACAAGACAAATAATAACTGCTATAAA
AACTGCAACAAGACAAAAACATATACCTTTAAATTCATATGTTTCTTTGAATAAACCAATATATGATGAAGAGTCAGACA
GAACACTTTTAGATATTATAGCTACAAGTATAGTAACAGATCCAGAAGAGCTTATAATTAGTAAAGAAGAGTTGAAAAAT
ATAGAATCAAAAATGAACGAATTGTTAAGTGACTTGGAATTAGAAGTACTAGAATTATATTTAAATGGAAAGTCATACCA
GTTTATAGCGGACAAGCTTAAAAGAGATGTAAAGTCAATAGATAACGCTTTACAAAGGGTTAAGAGAAAATTAGAAAAAC
ATCTTGAAAACAGAAATGATTAA

Upstream 100 bases:

>100_bases
TTAGATAAAGAAACATTGTCGAAACTTGAGAACATTCGTAGAAAGCGTTGAAATTACTAGGTTCTTTAGACTATAATATA
CCTATAAATTTGTTTTATAT

Downstream 100 bases:

>100_bases
TAGTAAAATACTTACCATAAGCTTATTGTGAGCAAAATTAATTTATATCGAAAGATAAGGGAGGAAATTCAAAATGGCTA
AAGCTAAATACGAAAGAACA

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MGEIYMLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNFVKAKAKSYFLIGADKEDIIQEGMIGLYKAVR
DFDGSKTNSFKCFAEICITRQIITAIKTATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKN
IESKMNELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND

Sequences:

>Translated_220_residues
MGEIYMLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNFVKAKAKSYFLIGADKEDIIQEGMIGLYKAVR
DFDGSKTNSFKCFAEICITRQIITAIKTATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKN
IESKMNELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND
>Mature_219_residues
GEIYMLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNFVKAKAKSYFLIGADKEDIIQEGMIGLYKAVRD
FDGSKTNSFKCFAEICITRQIITAIKTATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNI
ESKMNELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

None

Paralogues:

None

Copy number: <10 (log phase) 250 (stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014218
- InterPro:   IPR016371
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 25445; Mature: 25313

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00622 HTH_LUXR_1 ; PS00715 SIGMA70_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEIYMLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNFVKAKAKSYFLI
CCCEEEEEECCCCHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEE
GADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIKTATRQKHIPLNSY
ECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
VSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKMNELLSDLELEVLELY
EECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GEIYMLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNFVKAKAKSYFLI
CCEEEEEECCCCHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEE
GADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIKTATRQKHIPLNSY
ECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
VSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKMNELLSDLELEVLELY
EECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3277943; 6322121 [H]