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The map label for this gene is yacO [H]

Identifier: 126697621

GI number: 126697621

Start: 81662

End: 82408

Strand: Direct

Name: yacO [H]

Synonym: CD0055

Alternate gene names: 126697621

Gene position: 81662-82408 (Clockwise)

Preceding gene: 126697620

Following gene: 126697622

Centisome position: 1.9

GC content: 32.53

Gene sequence:

>747_bases
GTGAATAATTTGGCGAGTATAGAAGGAAGAAATCCGGTAATAGAAGCAATAAAAAGCGACAGAGAAATAGATAAAATATT
AATTGCAAATTCAGCTAAAGAAGGTTCAATTAAGAAAATAATAGGAATGGCTAAAGATAAGAATATAATTATTCAGTATG
TTGATAAACATAAGCTAGATGAAGTAAGTACAAGTCATTCACATCAAGGTGTAATAGCTTATGCAAGTGAGTATAAGTAT
TATGAATTAGATGAGCTAATAGATTTAGCAAAGAATAAAGATGAAGACCCATTTTTCATTATATTAGATGAGATAACAGA
CCCACATAATTTGGGTTCAATAATAAGGACAGCAGATGCAGTAGGAGCACATGGAGTTATCATTCCAAAAAGAAGGTCTG
TACACATAACTCCTGTAGTTGCCAAAGCATCTGCTGGAGCAGTAGAATATATGCCAGTTTGCAAGGTAACCAATATAGTT
AATACAATAAAAAGACTCAAAGAAGAAGGGCTGTGGATTGCTGCAGCTGATATGGATGGAGAAACTTTTTATAAACAAAA
TCTTACTGGTCCTCTTGGTGTAGTAATTGGAAGTGAAGGTTTTGGAATATCTAGATTGGTTAAACAAAACTGTGACTTTA
TAGTAAAAATGCCAATGATAGGTAATGTTACATCTTTAAATGCATCTGTAGCAGGTGGAATACTTTTATATGAGATATTC
AGACAAAGACTGGATAAAAGTAAATAG

Upstream 100 bases:

>100_bases
AAAGACTGGTCCAAGTTGTGTAAATGGAAGTTGTCCAGAAGGAACTATGACTTGTGGAGATATAGTTCAAGTTAGAGAAA
AATTTAAGGCCTTGTAGGAG

Downstream 100 bases:

>100_bases
GCATGAAAAAAAATATAAATCATTACTTAATAATAGATGGCTACAATATTATAAATGCGTGGGACAATTTGAAAGAACTG
GCTAAAGAGGACTTAGAAGA

Product: tRNA/rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNNLASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDKNIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKY
YELDELIDLAKNKDEDPFFIILDEITDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIV
NTIKRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIGNVTSLNASVAGGILLYEIF
RQRLDKSK

Sequences:

>Translated_248_residues
MNNLASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDKNIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKY
YELDELIDLAKNKDEDPFFIILDEITDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIV
NTIKRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIGNVTSLNASVAGGILLYEIF
RQRLDKSK
>Mature_248_residues
MNNLASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDKNIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKY
YELDELIDLAKNKDEDPFFIILDEITDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIV
NTIKRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIGNVTSLNASVAGGILLYEIF
RQRLDKSK

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=258, Percent_Identity=28.2945736434109, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1790623, Length=228, Percent_Identity=39.0350877192982, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1790083, Length=169, Percent_Identity=33.1360946745562, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788935, Length=190, Percent_Identity=27.3684210526316, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555908, Length=254, Percent_Identity=28.740157480315, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324775, Length=169, Percent_Identity=34.3195266272189, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27310; Mature: 27310

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDKNIIIQYVDKHKLD
CCCCCCCCCCCHHHHHHHCCCHHHEEEEECCCCCCCHHHHHHHCCCCCEEEEECCHHHHH
EVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEITDPHNLGSIIRTADA
HHCCCCCCCCEEEEECCCCEECHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
VGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTIKRLKEEGLWIAAADMDG
CCCCCEEECCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
ETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIGNVTSLNASVAGGILLYEIF
CHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHHHH
RQRLDKSK
HHHHCCCC
>Mature Secondary Structure
MNNLASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDKNIIIQYVDKHKLD
CCCCCCCCCCCHHHHHHHCCCHHHEEEEECCCCCCCHHHHHHHCCCCCEEEEECCHHHHH
EVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEITDPHNLGSIIRTADA
HHCCCCCCCCEEEEECCCCEECHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
VGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTIKRLKEEGLWIAAADMDG
CCCCCEEECCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
ETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIGNVTSLNASVAGGILLYEIF
CHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHHHH
RQRLDKSK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]