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The map label for this gene is kgtP [H]

Identifier: 126447960

GI number: 126447960

Start: 668387

End: 669706

Strand: Reverse

Name: kgtP [H]

Synonym: BMA10247_A0719

Alternate gene names: 126447960

Gene position: 669706-668387 (Counterclockwise)

Preceding gene: 126447424

Following gene: 126447480

Centisome position: 28.47

GC content: 66.59

Gene sequence:

>1320_bases
GTGTCGCAAGTCCGCTCTCTTGCTACTGCCCCCCATTGCCCGCCGGCCGGCACCCTCGCCCGCCTTCGTTCGATCTTCAG
CGGATCGGTCGGCAATCTGATCGAATACTACGACTGGTACGTGTACTCGGCGTTCTCGCTGTACTTCGCGAAGGTGTTCT
TTCCGTCCGGCAGCCAGACCGTGCAGTTGCTCAACACCGCGGCGATCTTCGCCGTCGGCTTCGTGATGCGGCCCATCGGC
GGCTGGCTCGTCGGCCTGTACGCGGACCGCAAGGGGCGCAAGGCCGCGCTGCTGGTCTCGGTGCTCGCGATGTGCGCCGG
CTCGCTGATCATCGGCCTCACGCCCGGCTACGGCAGCATCGGCATCGCGGCGCCCGTGCTGCTCGTTCTCGCGCGGCTGC
TGCAGGGCTTGAGCCTCGGCGGCGAATACGCGAGCTCGGCCACCTATCTGAGCGAGATGGCCGACAAGACCAACCGCGGC
TTCTATTCGAGCTTCCTGTTCGCGACGCTGTCGCTCGGCCAGTTGCTCGCGATGGCGGTGCTCGTCGCGCTGCAGCAGTT
CTTCCTGAGCGCCGCGCAACTCGAAAGCTGGGGCTGGCGCATTCCGTTCCTGATCGGCTCGCTCGCGGCGGGCGTCGCGA
TCTTCCTGCGCCGGAACATGGAGGAAACGGAATCGTTCGAGCAGCACCGGCAGAGCCGGCGCAGCCGCACGTCGGTCGCC
GAGCTGTTCCGGCACAAGCGCGCGTGCCTGATCGTCGCGGGCCTGACGCTCGGCGGCACCGTCGCGTTCTACGCATACAC
GACGTACATGCAGAAATTCCTCGTCAACAGCGCGGGGATGAGCAAGGCGGATGCGTCGATGGTGTCCGTCGCGAGCCTGA
TCGCGTTCGTGCTGATGCAACCGGTGTTCGGCAGCCTGTCGGACCGCGTCGGGCGGCGCCCGCTGCTGATCGCCTTCGGC
GTGCTCGGCACGCTGTGCACGGTTCCGATCTTCAGCGCGCTGACGACGGTCAGGACGATGGGCGGCGCGCTCGCGCTGAT
CTCCGCGGCGCTGCTGATCGTGAGCCTCTATTCGTCCGTCAGCGCGGTCGCGAAAGCCGAGCTGTTCCCGGTCGAGATCC
GCGCACTCGGCGTCGGGCTGCCCTACGCGATCACGGTGTCGCTGTTCGGCGGCACGGCCGAGTACATCGCGCTGTGGACC
AAGAGCATCGGCCACGAGACCTGGTTCTTCTGGTACGTGTCCGGGTGCGTGCTGGTGTCGCTGCTGTGCTATCTGTGGAT
GCCCGATCCGAAGACGGTCTCCTGCATCGATCGGGACTGA

Upstream 100 bases:

>100_bases
CTGCGCCCCCTCTTACCCTTGCTGAACTCGACCGCGCGCCGTCGTCCGGCGTCGGCATCCGCACACGGGTCATGAAGACA
ATCGAAACCGGAGACATCAC

Downstream 100 bases:

>100_bases
AGCCGGCCAGTTCGGCGGCGCGCGCGAGCGGGATGAACAGCCGCATGGCGGCCGGGCGTCCCGCTCGCCGGTTTGTTGGT
TCGCCGGTTTGTTGGTTTGT

Product: MFS transporter, metabolite:H+ symporter (MHS) family protein

Products: Proton [Cytoplasm]; 2-oxoglutarate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSQVRSLATAPHCPPAGTLARLRSIFSGSVGNLIEYYDWYVYSAFSLYFAKVFFPSGSQTVQLLNTAAIFAVGFVMRPIG
GWLVGLYADRKGRKAALLVSVLAMCAGSLIIGLTPGYGSIGIAAPVLLVLARLLQGLSLGGEYASSATYLSEMADKTNRG
FYSSFLFATLSLGQLLAMAVLVALQQFFLSAAQLESWGWRIPFLIGSLAAGVAIFLRRNMEETESFEQHRQSRRSRTSVA
ELFRHKRACLIVAGLTLGGTVAFYAYTTYMQKFLVNSAGMSKADASMVSVASLIAFVLMQPVFGSLSDRVGRRPLLIAFG
VLGTLCTVPIFSALTTVRTMGGALALISAALLIVSLYSSVSAVAKAELFPVEIRALGVGLPYAITVSLFGGTAEYIALWT
KSIGHETWFFWYVSGCVLVSLLCYLWMPDPKTVSCIDRD

Sequences:

>Translated_439_residues
MSQVRSLATAPHCPPAGTLARLRSIFSGSVGNLIEYYDWYVYSAFSLYFAKVFFPSGSQTVQLLNTAAIFAVGFVMRPIG
GWLVGLYADRKGRKAALLVSVLAMCAGSLIIGLTPGYGSIGIAAPVLLVLARLLQGLSLGGEYASSATYLSEMADKTNRG
FYSSFLFATLSLGQLLAMAVLVALQQFFLSAAQLESWGWRIPFLIGSLAAGVAIFLRRNMEETESFEQHRQSRRSRTSVA
ELFRHKRACLIVAGLTLGGTVAFYAYTTYMQKFLVNSAGMSKADASMVSVASLIAFVLMQPVFGSLSDRVGRRPLLIAFG
VLGTLCTVPIFSALTTVRTMGGALALISAALLIVSLYSSVSAVAKAELFPVEIRALGVGLPYAITVSLFGGTAEYIALWT
KSIGHETWFFWYVSGCVLVSLLCYLWMPDPKTVSCIDRD
>Mature_438_residues
SQVRSLATAPHCPPAGTLARLRSIFSGSVGNLIEYYDWYVYSAFSLYFAKVFFPSGSQTVQLLNTAAIFAVGFVMRPIGG
WLVGLYADRKGRKAALLVSVLAMCAGSLIIGLTPGYGSIGIAAPVLLVLARLLQGLSLGGEYASSATYLSEMADKTNRGF
YSSFLFATLSLGQLLAMAVLVALQQFFLSAAQLESWGWRIPFLIGSLAAGVAIFLRRNMEETESFEQHRQSRRSRTSVAE
LFRHKRACLIVAGLTLGGTVAFYAYTTYMQKFLVNSAGMSKADASMVSVASLIAFVLMQPVFGSLSDRVGRRPLLIAFGV
LGTLCTVPIFSALTTVRTMGGALALISAALLIVSLYSSVSAVAKAELFPVEIRALGVGLPYAITVSLFGGTAEYIALWTK
SIGHETWFFWYVSGCVLVSLLCYLWMPDPKTVSCIDRD

Specific function: Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788942, Length=408, Percent_Identity=52.9411764705882, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1790550, Length=393, Percent_Identity=32.0610687022901, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788292, Length=431, Percent_Identity=31.7865429234339, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789941, Length=419, Percent_Identity=31.0262529832936, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI87082231, Length=304, Percent_Identity=29.6052631578947, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082404, Length=367, Percent_Identity=23.433242506812, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 47337; Mature: 47206

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVRSLATAPHCPPAGTLARLRSIFSGSVGNLIEYYDWYVYSAFSLYFAKVFFPSGSQT
CCHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VQLLNTAAIFAVGFVMRPIGGWLVGLYADRKGRKAALLVSVLAMCAGSLIIGLTPGYGSI
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCH
GIAAPVLLVLARLLQGLSLGGEYASSATYLSEMADKTNRGFYSSFLFATLSLGQLLAMAV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVALQQFFLSAAQLESWGWRIPFLIGSLAAGVAIFLRRNMEETESFEQHRQSRRSRTSVA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ELFRHKRACLIVAGLTLGGTVAFYAYTTYMQKFLVNSAGMSKADASMVSVASLIAFVLMQ
HHHHCCCCEEEEEECHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
PVFGSLSDRVGRRPLLIAFGVLGTLCTVPIFSALTTVRTMGGALALISAALLIVSLYSSV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAVAKAELFPVEIRALGVGLPYAITVSLFGGTAEYIALWTKSIGHETWFFWYVSGCVLVS
HHHHHHHCCEEEHHHCCCCCCHHEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LLCYLWMPDPKTVSCIDRD
HHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQVRSLATAPHCPPAGTLARLRSIFSGSVGNLIEYYDWYVYSAFSLYFAKVFFPSGSQT
CHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VQLLNTAAIFAVGFVMRPIGGWLVGLYADRKGRKAALLVSVLAMCAGSLIIGLTPGYGSI
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCH
GIAAPVLLVLARLLQGLSLGGEYASSATYLSEMADKTNRGFYSSFLFATLSLGQLLAMAV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVALQQFFLSAAQLESWGWRIPFLIGSLAAGVAIFLRRNMEETESFEQHRQSRRSRTSVA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ELFRHKRACLIVAGLTLGGTVAFYAYTTYMQKFLVNSAGMSKADASMVSVASLIAFVLMQ
HHHHCCCCEEEEEECHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
PVFGSLSDRVGRRPLLIAFGVLGTLCTVPIFSALTTVRTMGGALALISAALLIVSLYSSV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAVAKAELFPVEIRALGVGLPYAITVSLFGGTAEYIALWTKSIGHETWFFWYVSGCVLVS
HHHHHHHCCEEEHHHCCCCCCHHEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LLCYLWMPDPKTVSCIDRD
HHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 2-oxoglutarate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 2-oxoglutarate [Periplasm] = Proton [Cytoplasm] + 2-oxoglutarate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2118499; 9205837; 9278503; 1709493; 2190187; 2053984; 8419306 [H]