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The map label for this gene is bigR [H]

Identifier: 126446892

GI number: 126446892

Start: 1367590

End: 1367937

Strand: Reverse

Name: bigR [H]

Synonym: BMA10247_A1404

Alternate gene names: 126446892

Gene position: 1367937-1367590 (Counterclockwise)

Preceding gene: 126446068

Following gene: 126446291

Centisome position: 58.14

GC content: 64.08

Gene sequence:

>348_bases
ATGAGCGCTGCTTGCTCGCCGATCGACTTGTCCGGCATGCGCGCATCGGCGGACGCCGCGTGCGCGCTGCTGAAAGTGCT
GTCGAATCCGGATCGATTGCTGATGATGTGCGAGCTCGCACAATGCGGCGAGCTGTGCGTGAGCGACATCGAGGCGCGGC
TCGATATCCATCAGCCGACGCTGTCGCAACAGCTCGGCGTGTTGCGCGAGCATGCGCTCGTCGATACGCGGCGCGACGGC
AAGAACATTTACTACGCGCTGACGAGCGAGCCCGCGGTCGCCATCATGGCCGTGCTCTACGAGCAGTTCTGCGCGACGCA
CCAAAAGGGAAAGCGCCGTGGCCGTTGA

Upstream 100 bases:

>100_bases
CCGGTTCGGATGGTGCGGCGCGATCGCGCGACCCTTGCATTTCCGTCATTCATTATGTAAAAATATATAATGTAATTCAA
TGGATTGTTGAGGTGAGGCG

Downstream 100 bases:

>100_bases
TTTCGTTCATTTCACGCCGGGCCTGTCGTTCGCGGGTGGCCTGTTGATCGGCGCCGCGGCGGCGCTGCTCGTGTTCTTCG
ACGGCCGCATCGCCGGCATC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 114

Protein sequence:

>115_residues
MSAACSPIDLSGMRASADAACALLKVLSNPDRLLMMCELAQCGELCVSDIEARLDIHQPTLSQQLGVLREHALVDTRRDG
KNIYYALTSEPAVAIMAVLYEQFCATHQKGKRRGR

Sequences:

>Translated_115_residues
MSAACSPIDLSGMRASADAACALLKVLSNPDRLLMMCELAQCGELCVSDIEARLDIHQPTLSQQLGVLREHALVDTRRDG
KNIYYALTSEPAVAIMAVLYEQFCATHQKGKRRGR
>Mature_114_residues
SAACSPIDLSGMRASADAACALLKVLSNPDRLLMMCELAQCGELCVSDIEARLDIHQPTLSQQLGVLREHALVDTRRDGK
NIYYALTSEPAVAIMAVLYEQFCATHQKGKRRGR

Specific function: Represses an operon that comprises at least itself and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=96, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12593; Mature: 12462

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAACSPIDLSGMRASADAACALLKVLSNPDRLLMMCELAQCGELCVSDIEARLDIHQPT
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
LSQQLGVLREHALVDTRRDGKNIYYALTSEPAVAIMAVLYEQFCATHQKGKRRGR
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAACSPIDLSGMRASADAACALLKVLSNPDRLLMMCELAQCGELCVSDIEARLDIHQPT
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
LSQQLGVLREHALVDTRRDGKNIYYALTSEPAVAIMAVLYEQFCATHQKGKRRGR
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]