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The map label for this gene is dehII-1 [H]

Identifier: 126446217

GI number: 126446217

Start: 223961

End: 224971

Strand: Direct

Name: dehII-1 [H]

Synonym: BMA10247_A0260

Alternate gene names: 126446217

Gene position: 223961-224971 (Clockwise)

Preceding gene: 126445704

Following gene: 126447166

Centisome position: 9.52

GC content: 71.22

Gene sequence:

>1011_bases
GTGCGCGATGAAGCCGGCCTCTATTTCTCGCCGGGCATGCAGGCAGGCGGTTCGCCGATAATGTCGGACGGCAGAGGTGC
GTTTCTTTCGGACGTGCAGGCGCGGCGGTCCGCGCGTGGCGGATCGTACGGGGCGGTCCTGCGTTCGTCGCCCAGGCGCG
CGCCGCCGGCCGGCGCGCGGCTCGCCGCGGCGTTCGGCCGGGCGCGCGCGTTCGGCGTCGGGCCGGTGCGAGCCGCCGAC
GGCGGCCGCTGCATCCTGAAACGTCATCCCACGACTCAGGAGAACATCATGCAGACGCTTGGCGTGAAGGCATTGGTATT
CGACGTGTTCGGCACCGTGGTCGACTGGCGTTCCGGCGTCATTCGCGACGCGACGCCGTTCCTCGCGAAGTACGGCGGCG
CGGGAGCCGATCCGGCCGCGTTCGCGGATGCATGGCGCGCGGGCTATTCGCCCGCGATGGAGGAGGTGCGCAGCGGCCGC
CGGCCGTTCACGCGGCTCGACGTGCTGCACCGGGAGAATCTCGACGCGCTGCTGCCCGCGTTCGGCATCGATCGCGCGAG
CGTGGCCGACGCCGATCTCGACGCGCTGAACCTCGCATGGCACCGGCTCGATCCGTGGCCCGATTCGGTCGCGGGGCTCA
CGCGGCTGAAGGCGCATTACATCATCGCGCCGCTGTCGAACGGCAACGTGATCCTGATGATCGACATGGCCAAGCGCGCG
GGGCTGCCGTGGGACGCGATCCTCGGCGCCGAGGTGGCGCAGGCGTACAAGCCGACGCCCGAAGCGTACCTGCGCACGGC
CGATATCCTCGCGCTGCGTCCGGATGAGGTGTGCCTCGTCGCCGCGCACAACGGCGACCTCGCGGCCGCGCGGCGCTGCG
GCTATCGCACCGCGTTCGTCGCGCGAGCGCGCGAGCATGGTCCCGCGCAGACCACCGATCTGCGCGCGGAGCAGGATTGG
GACGTCGTCGCGGCCGATTTCATCGAGCTCGCGCAGCGCTTCGGCGCGTGA

Upstream 100 bases:

>100_bases
CCGGGCGCGGCGACGGCGGCCCGCTTGTCCGGCGTCGTGCGCCCGTGCGCTTGCGTGCTTGCGTGCCCGTGTGCCCGTGT
GCTTGCGTGCCCGTGCGCTC

Downstream 100 bases:

>100_bases
CGGACGGCCGCGCGGCGGGGGCGGGTTCGCGCGGCGGTTCACGCGGCGGGGCGCGGATCGGTCCGTGCGTCGATCCGCGC
ATCGGCCCGCATACCGGCCC

Product: haloacid dehalogenase, type II

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase IVA; Halocarboxylic acid halidohydrolase IVA; L-2-haloacid dehalogenase IVA [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MRDEAGLYFSPGMQAGGSPIMSDGRGAFLSDVQARRSARGGSYGAVLRSSPRRAPPAGARLAAAFGRARAFGVGPVRAAD
GGRCILKRHPTTQENIMQTLGVKALVFDVFGTVVDWRSGVIRDATPFLAKYGGAGADPAAFADAWRAGYSPAMEEVRSGR
RPFTRLDVLHRENLDALLPAFGIDRASVADADLDALNLAWHRLDPWPDSVAGLTRLKAHYIIAPLSNGNVILMIDMAKRA
GLPWDAILGAEVAQAYKPTPEAYLRTADILALRPDEVCLVAAHNGDLAAARRCGYRTAFVARAREHGPAQTTDLRAEQDW
DVVAADFIELAQRFGA

Sequences:

>Translated_336_residues
MRDEAGLYFSPGMQAGGSPIMSDGRGAFLSDVQARRSARGGSYGAVLRSSPRRAPPAGARLAAAFGRARAFGVGPVRAAD
GGRCILKRHPTTQENIMQTLGVKALVFDVFGTVVDWRSGVIRDATPFLAKYGGAGADPAAFADAWRAGYSPAMEEVRSGR
RPFTRLDVLHRENLDALLPAFGIDRASVADADLDALNLAWHRLDPWPDSVAGLTRLKAHYIIAPLSNGNVILMIDMAKRA
GLPWDAILGAEVAQAYKPTPEAYLRTADILALRPDEVCLVAAHNGDLAAARRCGYRTAFVARAREHGPAQTTDLRAEQDW
DVVAADFIELAQRFGA
>Mature_336_residues
MRDEAGLYFSPGMQAGGSPIMSDGRGAFLSDVQARRSARGGSYGAVLRSSPRRAPPAGARLAAAFGRARAFGVGPVRAAD
GGRCILKRHPTTQENIMQTLGVKALVFDVFGTVVDWRSGVIRDATPFLAKYGGAGADPAAFADAWRAGYSPAMEEVRSGR
RPFTRLDVLHRENLDALLPAFGIDRASVADADLDALNLAWHRLDPWPDSVAGLTRLKAHYIIAPLSNGNVILMIDMAKRA
GLPWDAILGAEVAQAYKPTPEAYLRTADILALRPDEVCLVAAHNGDLAAARRCGYRTAFVARAREHGPAQTTDLRAEQDW
DVVAADFIELAQRFGA

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-3 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006388
- InterPro:   IPR006402
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 36062; Mature: 36062

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDEAGLYFSPGMQAGGSPIMSDGRGAFLSDVQARRSARGGSYGAVLRSSPRRAPPAGAR
CCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHH
LAAAFGRARAFGVGPVRAADGGRCILKRHPTTQENIMQTLGVKALVFDVFGTVVDWRSGV
HHHHHHHHHCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IRDATPFLAKYGGAGADPAAFADAWRAGYSPAMEEVRSGRRPFTRLDVLHRENLDALLPA
CCCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCHHHHHHH
FGIDRASVADADLDALNLAWHRLDPWPDSVAGLTRLKAHYIIAPLSNGNVILMIDMAKRA
CCCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCEEEEEEEECCCCEEEEEEEHHHC
GLPWDAILGAEVAQAYKPTPEAYLRTADILALRPDEVCLVAAHNGDLAAARRCGYRTAFV
CCCHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCEEEEEECCCCHHHHHHCCCHHHHH
ARAREHGPAQTTDLRAEQDWDVVAADFIELAQRFGA
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDEAGLYFSPGMQAGGSPIMSDGRGAFLSDVQARRSARGGSYGAVLRSSPRRAPPAGAR
CCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHH
LAAAFGRARAFGVGPVRAADGGRCILKRHPTTQENIMQTLGVKALVFDVFGTVVDWRSGV
HHHHHHHHHCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IRDATPFLAKYGGAGADPAAFADAWRAGYSPAMEEVRSGRRPFTRLDVLHRENLDALLPA
CCCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCHHHHHHH
FGIDRASVADADLDALNLAWHRLDPWPDSVAGLTRLKAHYIIAPLSNGNVILMIDMAKRA
CCCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCEEEEEEEECCCCEEEEEEEHHHC
GLPWDAILGAEVAQAYKPTPEAYLRTADILALRPDEVCLVAAHNGDLAAARRCGYRTAFV
CCCHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCEEEEEECCCCHHHHHHCCCHHHHH
ARAREHGPAQTTDLRAEQDWDVVAADFIELAQRFGA
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1376111 [H]