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The map label for this gene is cheB2

Identifier: 126445704

GI number: 126445704

Start: 222830

End: 223858

Strand: Direct

Name: cheB2

Synonym: BMA10247_A0259

Alternate gene names: 126445704

Gene position: 222830-223858 (Clockwise)

Preceding gene: 126447289

Following gene: 126446217

Centisome position: 9.47

GC content: 72.11

Gene sequence:

>1029_bases
ATGAACATCGGCATCGTCAACGACTTGCCGCTCGCCGTCGAGGCGCTGCGCCGCACGATCGCACTGCGGCCCGAGCACCG
CGTGCTGTGGGTCGCGACGGACGGCGCGCAGGCGCTCGACTTCTGCGTCGCGCAGCCGCCGGACCTCGTCCTGATGGATC
TCGTGATGCCGCGCATCGATGGCGTATCGGCGACGCGCAGCATCATGGAGCGCTCGCCGTGCGCGATCCTCATCGTCACC
GCGAACGTCGGCGCGAACGCGTCGTACGTCTACGAGGCGATGGGCGCGGGCGCGCTCGACGCGGTCGACACGCCGACGCT
TGAGCAGGGCGGCAGCGCCGATCCGTCGCAGCCGCTGCTCGCGAAGATCGACCAGATCGGCCGGCTGCTCGCGACGCGCA
TGCCGCTCGCCGCGCCCGCCGCCGCCGCGCCCGCGCCGCAGGGCGCGTTGCCGCCGCTCGTCGCGATCGGCGCGTCGGCG
GGCGGGCCGACCGCGCTGACCGCGCTGCTGCGGCGGCTGCCGGACGATTTTCCGGCGGCGCTCGTGATCGTCCAGCATGT
CGACCAGGCGTTCGCGATCGGCATGGCGCAGTGGCTCGACGGCTATTCGCCGTTGCCGGTGCGCATCGCGCGGCAGGGCA
GCGTGCCGCAGGCGGGCGAGGTGCTGCTCGCGGCGACCAACGATCACCTGCATCTGACGTCGCGCGGGGTGCTCGCGTAC
ACGCGGCGTCCGGAAGAGACGCCGTACCGGCCGTCGGTCGACGTGTTCTTTCACAGCGTCGTCGATCACTGGAAGGGCGA
GGCGATCGGCGTGCTGCTCACGGGCATGGGGCGCGACGGCGCGCTCGGCCTGAAGGCGATGCGCACGAAGGGGCATTACA
CGATCGCGCAGGACGAAGCGACGAGCGCGGTGTACGGGATGCCGAAGGCCGCGGCCGCGATCGGCGCGGCGAGCGCGGTG
CTGCCGCTCGAGCGGATCGCCGATCAGTTGATCTCGCTCGTTCAGCGCAACAGGCAGCGCTGGCGCTGA

Upstream 100 bases:

>100_bases
GCTCGAAGCGGGCGCCGACTATTACCTGGCGAAGGGCGGCTTCCATGACGAGGCGTTGCTCGACGCCGTGCACGACCTGA
TTGGGGACGCGTAGAAAGCC

Downstream 100 bases:

>100_bases
AGCCGGGCGCGGCGACGGCGGCCCGCTTGTCCGGCGTCGTGCGCCCGTGCGCTTGCGTGCTTGCGTGCCCGTGTGCCCGT
GTGCTTGCGTGCCCGTGCGC

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNIGIVNDLPLAVEALRRTIALRPEHRVLWVATDGAQALDFCVAQPPDLVLMDLVMPRIDGVSATRSIMERSPCAILIVT
ANVGANASYVYEAMGAGALDAVDTPTLEQGGSADPSQPLLAKIDQIGRLLATRMPLAAPAAAAPAPQGALPPLVAIGASA
GGPTALTALLRRLPDDFPAALVIVQHVDQAFAIGMAQWLDGYSPLPVRIARQGSVPQAGEVLLAATNDHLHLTSRGVLAY
TRRPEETPYRPSVDVFFHSVVDHWKGEAIGVLLTGMGRDGALGLKAMRTKGHYTIAQDEATSAVYGMPKAAAAIGAASAV
LPLERIADQLISLVQRNRQRWR

Sequences:

>Translated_342_residues
MNIGIVNDLPLAVEALRRTIALRPEHRVLWVATDGAQALDFCVAQPPDLVLMDLVMPRIDGVSATRSIMERSPCAILIVT
ANVGANASYVYEAMGAGALDAVDTPTLEQGGSADPSQPLLAKIDQIGRLLATRMPLAAPAAAAPAPQGALPPLVAIGASA
GGPTALTALLRRLPDDFPAALVIVQHVDQAFAIGMAQWLDGYSPLPVRIARQGSVPQAGEVLLAATNDHLHLTSRGVLAY
TRRPEETPYRPSVDVFFHSVVDHWKGEAIGVLLTGMGRDGALGLKAMRTKGHYTIAQDEATSAVYGMPKAAAAIGAASAV
LPLERIADQLISLVQRNRQRWR
>Mature_342_residues
MNIGIVNDLPLAVEALRRTIALRPEHRVLWVATDGAQALDFCVAQPPDLVLMDLVMPRIDGVSATRSIMERSPCAILIVT
ANVGANASYVYEAMGAGALDAVDTPTLEQGGSADPSQPLLAKIDQIGRLLATRMPLAAPAAAAPAPQGALPPLVAIGASA
GGPTALTALLRRLPDDFPAALVIVQHVDQAFAIGMAQWLDGYSPLPVRIARQGSVPQAGEVLLAATNDHLHLTSRGVLAY
TRRPEETPYRPSVDVFFHSVVDHWKGEAIGVLLTGMGRDGALGLKAMRTKGHYTIAQDEATSAVYGMPKAAAAIGAASAV
LPLERIADQLISLVQRNRQRWR

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=335, Percent_Identity=31.9402985074627, Blast_Score=157, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEB2_BURMA (Q4V2X4)

Other databases:

- EMBL:   CP000011
- RefSeq:   YP_338317.1
- ProteinModelPortal:   Q4V2X4
- SMR:   Q4V2X4
- GeneID:   3704284
- GenomeReviews:   CP000011_GR
- KEGG:   bma:BMAA0221.1
- TIGR:   BMAA0221.1
- HOGENOM:   HBG705324
- OMA:   FFESVVE
- ProtClustDB:   PRK12555
- BioCyc:   BMAL243160:BMA_A0221.1-MONOMER
- BRENDA:   3.1.1.61
- GO:   GO:0005737
- GO:   GO:0006935
- HAMAP:   MF_00099
- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876
- SMART:   SM00448

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg; SSF52738 Chemotax_RR_pGlu_Me-esterase; SSF52172 CheY_like

EC number: =3.1.1.61

Molecular weight: Translated: 36134; Mature: 36134

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50122 CHEB; PS50110 RESPONSE_REGULATORY

Important sites: ACT_SITE 159-159 ACT_SITE 186-186 ACT_SITE 279-279

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIVNDLPLAVEALRRTIALRPEHRVLWVATDGAQALDFCVAQPPDLVLMDLVMPRID
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHCCC
GVSATRSIMERSPCAILIVTANVGANASYVYEAMGAGALDAVDTPTLEQGGSADPSQPLL
CHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
AKIDQIGRLLATRMPLAAPAAAAPAPQGALPPLVAIGASAGGPTALTALLRRLPDDFPAA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCHHH
LVIVQHVDQAFAIGMAQWLDGYSPLPVRIARQGSVPQAGEVLLAATNDHLHLTSRGVLAY
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCEEEEECCCEEEE
TRRPEETPYRPSVDVFFHSVVDHWKGEAIGVLLTGMGRDGALGLKAMRTKGHYTIAQDEA
ECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHCCCCEEEECCCC
TSAVYGMPKAAAAIGAASAVLPLERIADQLISLVQRNRQRWR
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIGIVNDLPLAVEALRRTIALRPEHRVLWVATDGAQALDFCVAQPPDLVLMDLVMPRID
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHCCC
GVSATRSIMERSPCAILIVTANVGANASYVYEAMGAGALDAVDTPTLEQGGSADPSQPLL
CHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
AKIDQIGRLLATRMPLAAPAAAAPAPQGALPPLVAIGASAGGPTALTALLRRLPDDFPAA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCHHH
LVIVQHVDQAFAIGMAQWLDGYSPLPVRIARQGSVPQAGEVLLAATNDHLHLTSRGVLAY
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCEEEEECCCEEEE
TRRPEETPYRPSVDVFFHSVVDHWKGEAIGVLLTGMGRDGALGLKAMRTKGHYTIAQDEA
ECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHCCCCEEEECCCC
TSAVYGMPKAAAAIGAASAVLPLERIADQLISLVQRNRQRWR
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA