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The map label for this gene is lldD [H]

Identifier: 126446029

GI number: 126446029

Start: 274755

End: 276077

Strand: Direct

Name: lldD [H]

Synonym: BMA10247_A0315

Alternate gene names: 126446029

Gene position: 274755-276077 (Clockwise)

Preceding gene: 126447383

Following gene: 126446385

Centisome position: 11.68

GC content: 65.99

Gene sequence:

>1323_bases
GTGAGCGCAATGAGCGTGCGCATCCGGCGCCCGCCCGAAGACGAACGCCCGCGGTGCGCCGGCGGAGAACGGAGAAGAAT
TCAGATGGCCAATGTCGGCAAGGCTTGGAACATCGATGATTTGAGAAAAATGGCGCGAAAGCGCGTGCCCAAATATTTCT
TCGATTATCTGGACGGCGGCGCGAACAGCGAAACCACGATGCGCGCGAACGAAAACGATTTCGCGCGCTGGCGGCTGCGT
CAGAAAGTATTGACCGGCGCGCAGAGCCGGGTTGCGGGTTTGGGGGCGACATACCTCGGCGCCGAGCATCGGCTTCCGAT
TCTGCTCGGGCCGGTGGGATTTGCCGGCATGTATTGGTCGCGCGGCGAGATCGCGGCGGGACGCGCGGCCGACGACGCGG
GCATCGGTCAGTGTTTGTCGACGTTCTCGATCTGTTCGCTCGAGGATGTCGCCGCGGCGCGCTCCGGTCCGCTGTATTTT
CAGCTCTACATGTTCCGCGATCGCGATCTGACCGAGGACATTCTCGCGCGCTGCCGGCTGGCGAACGTCGACGCCGTCTT
TCTGACGGTGGACACCTGCTATATCCCGATTCGCGAACGCGATGCGCGCAACGGGTTTCGTGCCGATACGCGCTTGTCGG
CGCGCGGGGTATGGTCGATGCTCAAGCGCCCGGGCTGGTGCGCCGGTGCGTTGTCCCATGGCGTGCCGAGGATCGGCAAC
GTGCTGCGCTATCCGGAGCTTGGCGCATCGTTGCTCGAGCAATCCGCGGCGGTCGGCCGGATGATCGAGACGCGCTTGTC
CTGGGCCGACGTCAAGTGGCTGCGCGCGCGCTGGCCCGGCAGGATCGTCATCAAGGGGATTCTCGATCCCGACGACGCGC
GGCGCGCGGTCGACGAGGGCGTCGACGGCATCCTGATCTCGAATCATGGCGGCCGGCAACTCGATCCGGCGCCGTCGGTG
ATGGACGTGTTGCCGGAGATCGCCGAGGCGGTCGGCAAGCGCACCGAGATCCTGATGGACGGCGGTGTGCGGCGCGGTGC
GGACGTGATCAAGGCGCTGGCGCTCGGGGCCAGCGCGGTCTCGATCGGGCGCGCCTACGTCTATGGGCTCGGTGCGGCGG
GTGAGAAGGGCGTCTCGCGATGTCTCGAATTGCTGAAGGGCGAGATGCTGCCGGCGCTCAACATGATGGGCTTTGAATCG
ATCGCGGAACTCAGGGCCGCGGGCAAGTCCGCGTTGCGAATGGCGGTGCCGGTTCATGGCGCGACGGCGGTTGTCGAAGG
GGCGGAGGGCGGGGCGCGTAGACTGACGGAGAGCGTGCTGTAG

Upstream 100 bases:

>100_bases
GGCCGATGAAGATCACATTAGAATGTCCATGATGCAGTCGAGGTGGAAATCCTGCTGGATCGGAATGATTGCGACGAAGA
CCTGATCGCGGTGCGCCGGT

Downstream 100 bases:

>100_bases
CGTCAACGTGCCGATGGCGTGCCGTGGCGCCGCAACCGGCGGCGCACGGCGCTCATCACGCAGGCTACTTGCAGACGTCG
ACCCATTCGGCTTCGACCAG

Product: FMN-dependent dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSAMSVRIRRPPEDERPRCAGGERRRIQMANVGKAWNIDDLRKMARKRVPKYFFDYLDGGANSETTMRANENDFARWRLR
QKVLTGAQSRVAGLGATYLGAEHRLPILLGPVGFAGMYWSRGEIAAGRAADDAGIGQCLSTFSICSLEDVAAARSGPLYF
QLYMFRDRDLTEDILARCRLANVDAVFLTVDTCYIPIRERDARNGFRADTRLSARGVWSMLKRPGWCAGALSHGVPRIGN
VLRYPELGASLLEQSAAVGRMIETRLSWADVKWLRARWPGRIVIKGILDPDDARRAVDEGVDGILISNHGGRQLDPAPSV
MDVLPEIAEAVGKRTEILMDGGVRRGADVIKALALGASAVSIGRAYVYGLGAAGEKGVSRCLELLKGEMLPALNMMGFES
IAELRAAGKSALRMAVPVHGATAVVEGAEGGARRLTESVL

Sequences:

>Translated_440_residues
MSAMSVRIRRPPEDERPRCAGGERRRIQMANVGKAWNIDDLRKMARKRVPKYFFDYLDGGANSETTMRANENDFARWRLR
QKVLTGAQSRVAGLGATYLGAEHRLPILLGPVGFAGMYWSRGEIAAGRAADDAGIGQCLSTFSICSLEDVAAARSGPLYF
QLYMFRDRDLTEDILARCRLANVDAVFLTVDTCYIPIRERDARNGFRADTRLSARGVWSMLKRPGWCAGALSHGVPRIGN
VLRYPELGASLLEQSAAVGRMIETRLSWADVKWLRARWPGRIVIKGILDPDDARRAVDEGVDGILISNHGGRQLDPAPSV
MDVLPEIAEAVGKRTEILMDGGVRRGADVIKALALGASAVSIGRAYVYGLGAAGEKGVSRCLELLKGEMLPALNMMGFES
IAELRAAGKSALRMAVPVHGATAVVEGAEGGARRLTESVL
>Mature_439_residues
SAMSVRIRRPPEDERPRCAGGERRRIQMANVGKAWNIDDLRKMARKRVPKYFFDYLDGGANSETTMRANENDFARWRLRQ
KVLTGAQSRVAGLGATYLGAEHRLPILLGPVGFAGMYWSRGEIAAGRAADDAGIGQCLSTFSICSLEDVAAARSGPLYFQ
LYMFRDRDLTEDILARCRLANVDAVFLTVDTCYIPIRERDARNGFRADTRLSARGVWSMLKRPGWCAGALSHGVPRIGNV
LRYPELGASLLEQSAAVGRMIETRLSWADVKWLRARWPGRIVIKGILDPDDARRAVDEGVDGILISNHGGRQLDPAPSVM
DVLPEIAEAVGKRTEILMDGGVRRGADVIKALALGASAVSIGRAYVYGLGAAGEKGVSRCLELLKGEMLPALNMMGFESI
AELRAAGKSALRMAVPVHGATAVVEGAEGGARRLTESVL

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=368, Percent_Identity=38.8586956521739, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI54234014, Length=368, Percent_Identity=35.054347826087, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI7705393, Length=368, Percent_Identity=35.054347826087, Blast_Score=209, Evalue=6e-54,
Organism=Escherichia coli, GI1790033, Length=366, Percent_Identity=40.4371584699454, Blast_Score=262, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI193208036, Length=372, Percent_Identity=34.1397849462366, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI32566217, Length=282, Percent_Identity=30.4964539007092, Blast_Score=124, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6323587, Length=415, Percent_Identity=29.3975903614458, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI78707188, Length=371, Percent_Identity=33.4231805929919, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281363140, Length=371, Percent_Identity=33.4231805929919, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI78707190, Length=371, Percent_Identity=33.4231805929919, Blast_Score=187, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 47868; Mature: 47737

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAMSVRIRRPPEDERPRCAGGERRRIQMANVGKAWNIDDLRKMARKRVPKYFFDYLDGG
CCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHCCC
ANSETTMRANENDFARWRLRQKVLTGAQSRVAGLGATYLGAEHRLPILLGPVGFAGMYWS
CCCCCEEECCCCHHHHHHHHHHHHHCHHHHHHHCCHHHCCCCCCCCEEECCCCHHCCEEC
RGEIAAGRAADDAGIGQCLSTFSICSLEDVAAARSGPLYFQLYMFRDRDLTEDILARCRL
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHH
ANVDAVFLTVDTCYIPIRERDARNGFRADTRLSARGVWSMLKRPGWCAGALSHGVPRIGN
CCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHH
VLRYPELGASLLEQSAAVGRMIETRLSWADVKWLRARWPGRIVIKGILDPDDARRAVDEG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCC
VDGILISNHGGRQLDPAPSVMDVLPEIAEAVGKRTEILMDGGVRRGADVIKALALGASAV
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCHHHH
SIGRAYVYGLGAAGEKGVSRCLELLKGEMLPALNMMGFESIAELRAAGKSALRMAVPVHG
HHHHHHEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHEEEEEECCC
ATAVVEGAEGGARRLTESVL
CEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
SAMSVRIRRPPEDERPRCAGGERRRIQMANVGKAWNIDDLRKMARKRVPKYFFDYLDGG
CCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHCCC
ANSETTMRANENDFARWRLRQKVLTGAQSRVAGLGATYLGAEHRLPILLGPVGFAGMYWS
CCCCCEEECCCCHHHHHHHHHHHHHCHHHHHHHCCHHHCCCCCCCCEEECCCCHHCCEEC
RGEIAAGRAADDAGIGQCLSTFSICSLEDVAAARSGPLYFQLYMFRDRDLTEDILARCRL
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHH
ANVDAVFLTVDTCYIPIRERDARNGFRADTRLSARGVWSMLKRPGWCAGALSHGVPRIGN
CCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHH
VLRYPELGASLLEQSAAVGRMIETRLSWADVKWLRARWPGRIVIKGILDPDDARRAVDEG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCC
VDGILISNHGGRQLDPAPSVMDVLPEIAEAVGKRTEILMDGGVRRGADVIKALALGASAV
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCHHHH
SIGRAYVYGLGAAGEKGVSRCLELLKGEMLPALNMMGFESIAELRAAGKSALRMAVPVHG
HHHHHHEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHEEEEEECCC
ATAVVEGAEGGARRLTESVL
CEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA