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The map label for this gene is cyoB [H]

Identifier: 126445747

GI number: 126445747

Start: 191838

End: 193844

Strand: Direct

Name: cyoB [H]

Synonym: BMA10247_A0226

Alternate gene names: 126445747

Gene position: 191838-193844 (Clockwise)

Preceding gene: 126446121

Following gene: 262192874

Centisome position: 8.15

GC content: 63.28

Gene sequence:

>2007_bases
ATGTTCGGTAAATTGACGCTTTCGGCGATCCCGTTCGATCAGCCGATCATCATGGGCGCGGGCGCGTTCATGGCGCTCGT
CGTGCTCGGGATTCTGGGCGCGCTCACCTATACGAAGCGCTGGAAATGGCTGTGGTGCGAGTGGCTCACGACCGTCGACC
ACAAGAAGCTCGGCGTGATGTACATCATCGTCGCGCTCATCATGCTGCTGCGCGGCTTCGCCGACGCGGTGATGATGCGC
CTGCAGCTCGCGCTCGCGTACAACGGGCCCGGCTATCTGCCGCCGCACCACTATGACCAGATCTTCACCGCGCACGGCGT
CATCATGATCTTCTTCATGGCGATGGCGTTCATGATCGGCCTGATGAACATCATCGTGCCGCTGCAGATCGGCGCGCGCG
ACGTCGCGTTTCCGTTCATCAATTCGCTGAGCTTCTGGATGACGGCGGTCTCGGCGATCCTGATCAACATCTCGCTCGTC
GTCGGCGAGTTCGCGCAGACGGGCTGGCTCGCGTATCCGCCGCTCTCGGAGCTGCAGTTCAGTCCGGGCGTCGGCGTCGA
CTATTACCTGTGGGCGCTGCAGATATCCGGCGTCGGCACGCTGCTCACGGGCGTGAACTTCTTCGTGACGATCCTGCGCA
TGCGCGCGCCCGGCATGACACTGATGAAGATGCCGGTGTTCACGTGGACGGCGCTCTGCACGAACGTGCTGATCATGGCG
TCGTTCCCGATCCTGACGGTCACGCTCGCGCTGCTCGGCCTCGACCGCTACCTCGGCATGCACTTCTTCACGAACGACGC
CGGCGGCAACGCGATGCTGTATCTGAACCTGATCTGGGCGTGGGGTCATCCGGAAGTCTACATCCTGATCCTGCCCGCGT
TCGGGATCTTCTCGGAAGTGGTCGCCACCTACGCGAAGAAGCCGCTGTTCGGCTACAAGACGATGGTGTACGCGTCGTGC
GCGATCATGGTGCTGTCGTTCCTCGTGTGGCTGCACCACTTCTTCACGATGGGTTCGGGCGCGAACGTGAACGCGTTCTT
CGGGATGATGACGATGGTGATCGCGATCCCGACCGGCGTGAAAGTGTTCAACTGGCTGTTCACGATCTATCGCGGCCGGC
TCGAATTCTCGACGCCGATCCTCTGGACGATCGGCTTCATGGTGACGTTCACGCTCGGCGGGATGACGGGCGTGATGATG
GCGATTCCCGGCGCGGACTTCGTGCTGCACAACAGCCTGTTCCTGATCGCGCACTTTCACAACGTGATCATCGGCGGCGT
GCTGTTTGGCTATCTCGCGGGCTTCAATTACTGGTTTCCGAAGGTGTTCGGCTTCAAGCTGAACGAGACGCTCGGCAAGG
CCGCGTTCTGGTTCTGGCAGGTCGGCTTCTATGTCGCGTTCGTGCCGCTGTATGTGCTCGGCTTCATGGGCATGACGCGC
CGCCTGAATCACTACGACAACCCCGCCTGGCATCCGTGGCTCATCGTCGCCGCGTGCGGCGCGGCGTTGATCGCGATCGG
CATCGCATGCCAGTTGCTGCAGCTCGCCGTCAGCCTGCGCGATCGGCGGCTGCCCGAGAACCGCGATCCGACGGGCGATC
CGTGGGGCGGACGCACGCTCGAATGGGCGACGGCTTCGCCGCCGCCCGCGTACAACTTCGCGACGATCCCGACCGTGCAC
GCGCTCGACGAGTTCGCATACCGCAAGGAGCGCGGACTCGGCATCGGCAAGCCGGCGGAGTATCGCGACATCCACATGCC
GTCGAACACGAGCGCGGGCCTTTTCGTCGGCGTGTTCAGCCTCGTGCTCGGCTTCGCGGCGGTATGGCACATCTGGTGGC
TCGCGATCGCGGCGCTCGCCGGCATCCTCGTGACGGTGATTGCGTATAGCGCGGGCGAGAACGACGGCTATTACATTCCG
GCCGACGCCGTGCGCAGGATCGAGGAAAAACGCGGCGGCGCGCGTTTCGTCGCGCGGCCGGCGCAAGTCGAACTGGAGGC
AAACTGA

Upstream 100 bases:

>100_bases
CGACGGTCGATCCTCGGCTCTTCAATAACATCATCGCGAAGTACAACGATGGCCGCGTCCTCGATCTGACGGACGCCGCC
TGTCGGACGAAGAGGTAAGC

Downstream 100 bases:

>100_bases
TGTCGTACCCATCCGTGAGCGCCGCGCCTCGTCACGCCGCGCACGATCATCCGCCGTCGCATTCGGTGTTCGGCTTCTGG
CTGTATCTGATGACCGACTG

Product: ubiquinol oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome A1 subunit 1; Oxidase BA(3) subunit 1; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MFGKLTLSAIPFDQPIIMGAGAFMALVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVMYIIVALIMLLRGFADAVMMR
LQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMAFMIGLMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLV
VGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEVVATYAKKPLFGYKTMVYASC
AIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGVKVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMM
AIPGADFVLHNSLFLIAHFHNVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLPENRDPTGDPWGGRTLEWATASPPPAYNFATIPTVH
ALDEFAYRKERGLGIGKPAEYRDIHMPSNTSAGLFVGVFSLVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYYIP
ADAVRRIEEKRGGARFVARPAQVELEAN

Sequences:

>Translated_668_residues
MFGKLTLSAIPFDQPIIMGAGAFMALVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVMYIIVALIMLLRGFADAVMMR
LQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMAFMIGLMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLV
VGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEVVATYAKKPLFGYKTMVYASC
AIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGVKVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMM
AIPGADFVLHNSLFLIAHFHNVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLPENRDPTGDPWGGRTLEWATASPPPAYNFATIPTVH
ALDEFAYRKERGLGIGKPAEYRDIHMPSNTSAGLFVGVFSLVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYYIP
ADAVRRIEEKRGGARFVARPAQVELEAN
>Mature_668_residues
MFGKLTLSAIPFDQPIIMGAGAFMALVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVMYIIVALIMLLRGFADAVMMR
LQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMAFMIGLMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLV
VGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEVVATYAKKPLFGYKTMVYASC
AIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGVKVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMM
AIPGADFVLHNSLFLIAHFHNVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLPENRDPTGDPWGGRTLEWATASPPPAYNFATIPTVH
ALDEFAYRKERGLGIGKPAEYRDIHMPSNTSAGLFVGVFSLVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYYIP
ADAVRRIEEKRGGARFVARPAQVELEAN

Specific function: Catalytic subunit of the enzyme. Electrons originating in a quinol are transferred to the bimetallic center formed by heme a and copper B [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=39.5303326810176, Blast_Score=336, Evalue=5e-92,
Organism=Escherichia coli, GI1786634, Length=652, Percent_Identity=67.6380368098159, Blast_Score=931, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=537, Percent_Identity=38.1750465549348, Blast_Score=355, Evalue=1e-98,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=43.3846153846154, Blast_Score=253, Evalue=9e-68,
Organism=Saccharomyces cerevisiae, GI6226523, Length=245, Percent_Identity=35.1020408163265, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74228; Mature: 74228

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLTLSAIPFDQPIIMGAGAFMALVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVM
CCCCEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHH
YIIVALIMLLRGFADAVMMRLQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMAFMIG
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLVVGEFAQTGWLAYPPLSELQF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHCCC
SPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
CCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEV
CCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHH
VATYAKKPLFGYKTMVYASCAIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
KVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMMAIPGADFVLHNSLFLIAHFH
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHCCHHHHHHHH
NVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
HHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLPENRDPTGDPWGGRTL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
EWATASPPPAYNFATIPTVHALDEFAYRKERGLGIGKPAEYRDIHMPSNTSAGLFVGVFS
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHH
LVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYYIPADAVRRIEEKRGGARFVARP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHCCCCEEEECC
AQVELEAN
CEEEEECC
>Mature Secondary Structure
MFGKLTLSAIPFDQPIIMGAGAFMALVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVM
CCCCEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHH
YIIVALIMLLRGFADAVMMRLQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMAFMIG
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLVVGEFAQTGWLAYPPLSELQF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHCCC
SPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
CCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEV
CCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHH
VATYAKKPLFGYKTMVYASCAIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
KVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMMAIPGADFVLHNSLFLIAHFH
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHCCHHHHHHHH
NVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
HHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLPENRDPTGDPWGGRTL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
EWATASPPPAYNFATIPTVHALDEFAYRKERGLGIGKPAEYRDIHMPSNTSAGLFVGVFS
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHH
LVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYYIPADAVRRIEEKRGGARFVARP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHCCCCEEEECC
AQVELEAN
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8392509 [H]