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The map label for this gene is xenA [H]

Identifier: 126445655

GI number: 126445655

Start: 1443619

End: 1444716

Strand: Reverse

Name: xenA [H]

Synonym: BMA10247_A1489

Alternate gene names: 126445655

Gene position: 1444716-1443619 (Counterclockwise)

Preceding gene: 126446290

Following gene: 126447912

Centisome position: 61.41

GC content: 71.68

Gene sequence:

>1098_bases
ATGGCCGCATTGTTCGAACCGTTTCAGTTGAAGGACGTCACGCTGCGCAACCGCATCGCGGTGCCGCCGATGTGCCAGTA
CGTCGCCGAGGATGGCGTGCCGAACGAATGGCATCACGTGCATCTCGCGGGCATCGCGCGCGGCGGCGCGGGGCTCGTGA
TCGCGGAGGCGACCGCGGTGTCGCCGGAAGGCCGCATCACGCCGGGCTGCACCGGTCTCTGGAGCGACGGGCAGGCCGCC
GCGTTCGCGCGCTCGGTCGCGGCGATCAAGGCGGCGGGCGCGGTGCCGGGCATCCAGCTCGCGCATGCGGGCCGCAAGGC
GAGCGCGAACCGGCCGTGGGAAGACGACGATCACATCGCCGACGGCGACCCGCGCGGCTGGCGGACGATCGCGCCTTCGG
CGGTGCCGTACGGCGCGCATCTGCCGAAGGTGCCGCGCGAGATGACGCTCGACGACATCGCGCGCGTGAAGGCCGATTAC
GTCGCGGCCGCGAAGCGCGCGCTCGACGCGGGCTTCGAATGGCTCGAGCTGCATTTCGCGCACGGCTATCTCGCGCAGAG
CTTCTTCTCCGTGCATTCGAACCGGCGCGCCGATGCGTACGGCGGTTCCGCGGAGAACCGCGGGCGCTTCCTTGTCGAGA
CGCTCGCGGCCGTGCGGGAAGTGTGGCCCGAGCGCCTGCCGCTCACCGCGCGCTTCGGCGTGATCGAGTACGACGGCCGC
GACGAGCAGACGCTCGCCGAATCGATCGAGCTCGCGAAGCGCTTCAAGCTCGAAGGGCTCGATCTGCTGAGCGTGACGAT
CGGTTTCTCGACGCCCGCCGCGCGCATTCCGTGGGGCCCCGCGTTTCTCGCGCCGGTTGCCGAGCGCGTGCGCCGCGAAG
CGCAACTGCCGGTGGCGTCCGCGTGGGGGATCGATGCGCCGGCGCTCGCGGAACGCGTCGTCCGCGAGGGGCAGCTCGAT
CTCGTGATGGTCGGCCGCGCGCATCTGGCCGACCCGCACTGGCCGTATCGCGCGGCGCTCGAGCTCGGTGTCGATCGCGC
GCCGTGGACGCTGCCCGCGCCGTATGCGCACTGGCTCGAGCGGTATCGGGCGGCGTGA

Upstream 100 bases:

>100_bases
ACGCCGCAGCGCCGTATCGCAGCATCACCGCATCGCCCGAATCACCTGAATCACCCGAATCACCCCACCGACCGCAACAC
GAATACCGAAGGAGTAGTAG

Downstream 100 bases:

>100_bases
CGGCGCGGCGCCCGGTGCGACCCACGCGCGGCGCGCATGCCGCGTCAGTGGACGGGGCGTGCGCGCGTTAGCCGTGGCGG
CCGCGGGGCTTCGAATGCAC

Product: xenobiotic reductase A

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MAALFEPFQLKDVTLRNRIAVPPMCQYVAEDGVPNEWHHVHLAGIARGGAGLVIAEATAVSPEGRITPGCTGLWSDGQAA
AFARSVAAIKAAGAVPGIQLAHAGRKASANRPWEDDDHIADGDPRGWRTIAPSAVPYGAHLPKVPREMTLDDIARVKADY
VAAAKRALDAGFEWLELHFAHGYLAQSFFSVHSNRRADAYGGSAENRGRFLVETLAAVREVWPERLPLTARFGVIEYDGR
DEQTLAESIELAKRFKLEGLDLLSVTIGFSTPAARIPWGPAFLAPVAERVRREAQLPVASAWGIDAPALAERVVREGQLD
LVMVGRAHLADPHWPYRAALELGVDRAPWTLPAPYAHWLERYRAA

Sequences:

>Translated_365_residues
MAALFEPFQLKDVTLRNRIAVPPMCQYVAEDGVPNEWHHVHLAGIARGGAGLVIAEATAVSPEGRITPGCTGLWSDGQAA
AFARSVAAIKAAGAVPGIQLAHAGRKASANRPWEDDDHIADGDPRGWRTIAPSAVPYGAHLPKVPREMTLDDIARVKADY
VAAAKRALDAGFEWLELHFAHGYLAQSFFSVHSNRRADAYGGSAENRGRFLVETLAAVREVWPERLPLTARFGVIEYDGR
DEQTLAESIELAKRFKLEGLDLLSVTIGFSTPAARIPWGPAFLAPVAERVRREAQLPVASAWGIDAPALAERVVREGQLD
LVMVGRAHLADPHWPYRAALELGVDRAPWTLPAPYAHWLERYRAA
>Mature_364_residues
AALFEPFQLKDVTLRNRIAVPPMCQYVAEDGVPNEWHHVHLAGIARGGAGLVIAEATAVSPEGRITPGCTGLWSDGQAAA
FARSVAAIKAAGAVPGIQLAHAGRKASANRPWEDDDHIADGDPRGWRTIAPSAVPYGAHLPKVPREMTLDDIARVKADYV
AAAKRALDAGFEWLELHFAHGYLAQSFFSVHSNRRADAYGGSAENRGRFLVETLAAVREVWPERLPLTARFGVIEYDGRD
EQTLAESIELAKRFKLEGLDLLSVTIGFSTPAARIPWGPAFLAPVAERVRREAQLPVASAWGIDAPALAERVVREGQLDL
VMVGRAHLADPHWPYRAALELGVDRAPWTLPAPYAHWLERYRAA

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=352, Percent_Identity=28.9772727272727, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1789463, Length=350, Percent_Identity=27.1428571428571, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=303, Percent_Identity=29.042904290429, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17565138, Length=313, Percent_Identity=25.8785942492013, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI72001454, Length=308, Percent_Identity=25.6493506493506, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17559802, Length=306, Percent_Identity=25.4901960784314, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559804, Length=264, Percent_Identity=26.8939393939394, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17564188, Length=263, Percent_Identity=25.4752851711027, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=229, Percent_Identity=31.4410480349345, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321973, Length=229, Percent_Identity=30.1310043668122, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39766; Mature: 39635

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALFEPFQLKDVTLRNRIAVPPMCQYVAEDGVPNEWHHVHLAGIARGGAGLVIAEATAV
CCCCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEEEEE
SPEGRITPGCTGLWSDGQAAAFARSVAAIKAAGAVPGIQLAHAGRKASANRPWEDDDHIA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCC
DGDPRGWRTIAPSAVPYGAHLPKVPREMTLDDIARVKADYVAAAKRALDAGFEWLELHFA
CCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HGYLAQSFFSVHSNRRADAYGGSAENRGRFLVETLAAVREVWPERLPLTARFGVIEYDGR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCEEEECCC
DEQTLAESIELAKRFKLEGLDLLSVTIGFSTPAARIPWGPAFLAPVAERVRREAQLPVAS
CHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
AWGIDAPALAERVVREGQLDLVMVGRAHLADPHWPYRAALELGVDRAPWTLPAPYAHWLE
CCCCCCHHHHHHHHHCCCCCEEEECCHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH
RYRAA
HHHCC
>Mature Secondary Structure 
AALFEPFQLKDVTLRNRIAVPPMCQYVAEDGVPNEWHHVHLAGIARGGAGLVIAEATAV
CCCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEEEEE
SPEGRITPGCTGLWSDGQAAAFARSVAAIKAAGAVPGIQLAHAGRKASANRPWEDDDHIA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCC
DGDPRGWRTIAPSAVPYGAHLPKVPREMTLDDIARVKADYVAAAKRALDAGFEWLELHFA
CCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HGYLAQSFFSVHSNRRADAYGGSAENRGRFLVETLAAVREVWPERLPLTARFGVIEYDGR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCEEEECCC
DEQTLAESIELAKRFKLEGLDLLSVTIGFSTPAARIPWGPAFLAPVAERVRREAQLPVAS
CHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
AWGIDAPALAERVVREGQLDLVMVGRAHLADPHWPYRAALELGVDRAPWTLPAPYAHWLE
CCCCCCHHHHHHHHHCCCCCEEEECCHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH
RYRAA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA