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The map label for this gene is phhB

Identifier: 126455335

GI number: 126455335

Start: 3980831

End: 3981223

Strand: Direct

Name: phhB

Synonym: BURPS1106A_4076

Alternate gene names: NA

Gene position: 3980831-3981223 (Clockwise)

Preceding gene: 126454218

Following gene: 126453172

Centisome position: 99.81

GC content: 60.31

Gene sequence:

>393_bases
TTGACGAACAATTATGGAAGAATGGCCGATACGGCGCGCCGCCGCGCGAATGGGCGCGGCCGCGCCGCTATTGGACGAGG
GACGAAAATGATTCACAAGCTCACATCGGAAGAACGCAAGACGCAGCTTGAAAGCCTGCACCACTGGACCGCCGTTCCCG
GCCGCGACGCGATCCAGCGCAGCCTGCGTTTCGCCGATTTCAACGAAGCGTTCGGCTTCATGACGCGCGTCGCGATCAAG
GCGCAGGAAATGAATCACCATCCCGAGTGGTTCAACGTCTACAACCGCGTCGATGTCACGCTCTCGACGCACGACGCCAA
CGGCCTTACCGAGCGCGATATCAAGCTCGCGCATTTCATCGACGAAGTGGGCAAGCACGCGAAGGCTGCGTGA

Upstream 100 bases:

>100_bases
GGCTCGCCGGCGCGCCCGAGCACGCGGCGGGCGCGGTGCTTGACGGCGATCATGTGCTCACGCGCGGCACCGGTGAAGGC
TGGGCAGCCGATGCAGACGC

Downstream 100 bases:

>100_bases
TTACCCTGATGGGGATTCGATTTCAGGTCGTCAACGTATCGCTTTCCGTAAGCGTTTTCTATGCTGAATGAAGCGAAAGC
CTTCAGCCTTCCAAGCCGTT

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MTNNYGRMADTARRRANGRGRAAIGRGTKMIHKLTSEERKTQLESLHHWTAVPGRDAIQRSLRFADFNEAFGFMTRVAIK
AQEMNHHPEWFNVYNRVDVTLSTHDANGLTERDIKLAHFIDEVGKHAKAA

Sequences:

>Translated_130_residues
MTNNYGRMADTARRRANGRGRAAIGRGTKMIHKLTSEERKTQLESLHHWTAVPGRDAIQRSLRFADFNEAFGFMTRVAIK
AQEMNHHPEWFNVYNRVDVTLSTHDANGLTERDIKLAHFIDEVGKHAKAA
>Mature_129_residues
TNNYGRMADTARRRANGRGRAAIGRGTKMIHKLTSEERKTQLESLHHWTAVPGRDAIQRSLRFADFNEAFGFMTRVAIKA
QEMNHHPEWFNVYNRVDVTLSTHDANGLTERDIKLAHFIDEVGKHAKAA

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI134133240, Length=113, Percent_Identity=49.5575221238938, Blast_Score=120, Evalue=4e-28,
Organism=Homo sapiens, GI4557831, Length=95, Percent_Identity=56.8421052631579, Blast_Score=119, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI115533705, Length=94, Percent_Identity=61.7021276595745, Blast_Score=127, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45549100, Length=91, Percent_Identity=54.9450549450549, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001533 [H]

Pfam domain/function: PF01329 Pterin_4a [H]

EC number: =4.2.1.96 [H]

Molecular weight: Translated: 14843; Mature: 14712

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNYGRMADTARRRANGRGRAAIGRGTKMIHKLTSEERKTQLESLHHWTAVPGRDAIQR
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLRFADFNEAFGFMTRVAIKAQEMNHHPEWFNVYNRVDVTLSTHDANGLTERDIKLAHFI
HHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHH
DEVGKHAKAA
HHHHHHCCCC
>Mature Secondary Structure 
TNNYGRMADTARRRANGRGRAAIGRGTKMIHKLTSEERKTQLESLHHWTAVPGRDAIQR
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLRFADFNEAFGFMTRVAIKAQEMNHHPEWFNVYNRVDVTLSTHDANGLTERDIKLAHFI
HHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHH
DEVGKHAKAA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA