Click here to switch to the map view.

The map label for this gene is xseA [H]

Identifier: 126455268

GI number: 126455268

Start: 914661

End: 916043

Strand: Direct

Name: xseA [H]

Synonym: BURPS1106A_0932

Alternate gene names: 126455268

Gene position: 914661-916043 (Clockwise)

Preceding gene: 126454496

Following gene: 126454128

Centisome position: 22.93

GC content: 73.9

Gene sequence:

>1383_bases
ATGCATTCCGAATCTCCCTTTGTCGGCTCCGGCGGCGCGCCCGCGGGCGACGGCGTCATTCCCGTGTCCGCGCTCAACCG
CGCGATCGGCACGATGCTCGAGCGCACGTTCCCGCTGCTGTGGGTGGCGGGCGAAGTGTCGAACTTCACGCGCGCGGCGA
GCGGCCACTGGTATTTCTCGATCAAGGATCAGCAGGCGCAGATGCGCTGCGTGATGTTCCGCGGCCGCGCGCAGCACGCG
GAGTTCACGCCGCGCGAAGGCGACAGGATCGAGGTGCGCGCGCTCGTCACGATGTACGAGCCGCGCGGCGAAGTGCAACT
GAGCGTCGAGGCGATCCGGCGCACCGGGCAGGGGCGGCTCTACGAAGCGTTCCTGCGGCTGAAGGCGCAGCTCGAAGCCG
AAGGGCTCTTCGCGCCCGAGCGCAAGCGGGCGCCGCCGACGCATCCGCGCGCGATCGGCATCGTCACGTCGCTGCAGGCG
GCCGCGCTGCGCGACGTGCTGACGACGCTCGCGCGCCGCGCGCCGCACGTGCCGGTGATCGTCTATCCGGCGCCCGTGCA
GGGCGCGGGCGCGGCGGAGAAGCTCGCCGCGATGGTCGCGACGGCGAACGCGCGGCGCGAGGTCGACGTGCTGATCGTCT
GCCGCGGCGGCGGCTCGATCGAGGACTTGTGGTCGTTCAATGACGAGGCGCTCGCGCGCGCGATCGCGGCGAGCGACGTG
CCGGTCGTCTGCGGCGTCGGCCACGAGACCGATTTCACGATCGCCGATTTCGCGGCCGACGTGCGCGCGCCGACGCCGAC
CGGCGCGGCGGAGCTCGTGAGCCCGCAGCGCGCGCTGCTGCTGCGCGAGCTCGGCGAGCGGCAGGGCGCGCTCGCGCGCG
GCCTGCGGCGTGGGCTCGACGCGCGCGCGCAGCAGCTCGACTGGCTCGCGCGCCGGCTGATCAGCCCGGCCGAGCGCCTG
CAGCGCCAGGCGATGCACGTGGGGCAGCTCGCCGCGCGGCTTGCCGCGGCGGGCGCGCGGCCCGTGCGCGACGCGCGCGC
GCGTTTTTCGCTCGTGCAATTGCGCTGGCAGCGCGCGCGGCCCGACTTCGCGCAGGCACGGCAGGTGCTCGCCGCGTTCG
CGCAAAGGCTCGATGCGACGCTGCAGCGGCGCCTCGAACGCGATACCGCACGCGTGGCCGCGTGCGCGGCGCGGCTCGAG
GTGCTGAGCCCGCAACGCACGCTGGAGCGCGGCTACGCGGCGCTCATCGACGCGCAGACGGGCCGCGCGGTGCGCGCGCC
CGCATCGCTCAAGCCGCAGCGCCGGCTGACCGTGCACCTTGCCGAGGGCTCGGCCGACGTATCGCTTGCCGACGTGCAAC
CGCGTCTTTCGGATACATTCTGA

Upstream 100 bases:

>100_bases
GTTTCGCGCGACGTGTGGAAACCTGGGCGGCGCGCACGCGCGGCTTGCCGCGCGCGCCGAGGCGGTCTATCGTTGGGCGC
CAGAAATTTTCCGACCGTCC

Downstream 100 bases:

>100_bases
CGATGTGGCGCGTGCGCGATACGCGGGCGGCGCGAGCCGTCCGCGTATCGCTTCGCGCGTGCCGCGCGAGCATCGATTTT
TCGGATGCGGCGGATAAAGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MHSESPFVGSGGAPAGDGVIPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQHA
EFTPREGDRIEVRALVTMYEPRGEVQLSVEAIRRTGQGRLYEAFLRLKAQLEAEGLFAPERKRAPPTHPRAIGIVTSLQA
AALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLAAMVATANARREVDVLIVCRGGGSIEDLWSFNDEALARAIAASDV
PVVCGVGHETDFTIADFAADVRAPTPTGAAELVSPQRALLLRELGERQGALARGLRRGLDARAQQLDWLARRLISPAERL
QRQAMHVGQLAARLAAAGARPVRDARARFSLVQLRWQRARPDFAQARQVLAAFAQRLDATLQRRLERDTARVAACAARLE
VLSPQRTLERGYAALIDAQTGRAVRAPASLKPQRRLTVHLAEGSADVSLADVQPRLSDTF

Sequences:

>Translated_460_residues
MHSESPFVGSGGAPAGDGVIPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQHA
EFTPREGDRIEVRALVTMYEPRGEVQLSVEAIRRTGQGRLYEAFLRLKAQLEAEGLFAPERKRAPPTHPRAIGIVTSLQA
AALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLAAMVATANARREVDVLIVCRGGGSIEDLWSFNDEALARAIAASDV
PVVCGVGHETDFTIADFAADVRAPTPTGAAELVSPQRALLLRELGERQGALARGLRRGLDARAQQLDWLARRLISPAERL
QRQAMHVGQLAARLAAAGARPVRDARARFSLVQLRWQRARPDFAQARQVLAAFAQRLDATLQRRLERDTARVAACAARLE
VLSPQRTLERGYAALIDAQTGRAVRAPASLKPQRRLTVHLAEGSADVSLADVQPRLSDTF
>Mature_460_residues
MHSESPFVGSGGAPAGDGVIPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQHA
EFTPREGDRIEVRALVTMYEPRGEVQLSVEAIRRTGQGRLYEAFLRLKAQLEAEGLFAPERKRAPPTHPRAIGIVTSLQA
AALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLAAMVATANARREVDVLIVCRGGGSIEDLWSFNDEALARAIAASDV
PVVCGVGHETDFTIADFAADVRAPTPTGAAELVSPQRALLLRELGERQGALARGLRRGLDARAQQLDWLARRLISPAERL
QRQAMHVGQLAARLAAAGARPVRDARARFSLVQLRWQRARPDFAQARQVLAAFAQRLDATLQRRLERDTARVAACAARLE
VLSPQRTLERGYAALIDAQTGRAVRAPASLKPQRRLTVHLAEGSADVSLADVQPRLSDTF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=440, Percent_Identity=40.4545454545455, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50052; Mature: 50052

Theoretical pI: Translated: 11.20; Mature: 11.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSESPFVGSGGAPAGDGVIPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYFS
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCEEEE
IKDQQAQMRCVMFRGRAQHAEFTPREGDRIEVRALVTMYEPRGEVQLSVEAIRRTGQGRL
ECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEEHHHHHHCCCCHH
YEAFLRLKAQLEAEGLFAPERKRAPPTHPRAIGIVTSLQAAALRDVLTTLARRAPHVPVI
HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VYPAPVQGAGAAEKLAAMVATANARREVDVLIVCRGGGSIEDLWSFNDEALARAIAASDV
EECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHCCCC
PVVCGVGHETDFTIADFAADVRAPTPTGAAELVSPQRALLLRELGERQGALARGLRRGLD
CEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHH
ARAQQLDWLARRLISPAERLQRQAMHVGQLAARLAAAGARPVRDARARFSLVQLRWQRAR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
PDFAQARQVLAAFAQRLDATLQRRLERDTARVAACAARLEVLSPQRTLERGYAALIDAQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHEEEECCC
GRAVRAPASLKPQRRLTVHLAEGSADVSLADVQPRLSDTF
CCEEECCCCCCCCCEEEEEEECCCCCEEEECCCCHHCCCC
>Mature Secondary Structure
MHSESPFVGSGGAPAGDGVIPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYFS
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCEEEE
IKDQQAQMRCVMFRGRAQHAEFTPREGDRIEVRALVTMYEPRGEVQLSVEAIRRTGQGRL
ECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEEHHHHHHCCCCHH
YEAFLRLKAQLEAEGLFAPERKRAPPTHPRAIGIVTSLQAAALRDVLTTLARRAPHVPVI
HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VYPAPVQGAGAAEKLAAMVATANARREVDVLIVCRGGGSIEDLWSFNDEALARAIAASDV
EECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHCCCC
PVVCGVGHETDFTIADFAADVRAPTPTGAAELVSPQRALLLRELGERQGALARGLRRGLD
CEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHH
ARAQQLDWLARRLISPAERLQRQAMHVGQLAARLAAAGARPVRDARARFSLVQLRWQRAR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
PDFAQARQVLAAFAQRLDATLQRRLERDTARVAACAARLEVLSPQRTLERGYAALIDAQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHEEEECCC
GRAVRAPASLKPQRRLTVHLAEGSADVSLADVQPRLSDTF
CCEEECCCCCCCCCEEEEEEECCCCCEEEECCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA