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The map label for this gene is fadN [H]

Identifier: 126455250

GI number: 126455250

Start: 671116

End: 673551

Strand: Direct

Name: fadN [H]

Synonym: BURPS1106A_0696

Alternate gene names: 126455250

Gene position: 671116-673551 (Clockwise)

Preceding gene: 126452094

Following gene: 126454517

Centisome position: 16.83

GC content: 67.41

Gene sequence:

>2436_bases
GTGAGCAATTTCAACATTCGCAAGGTTGCCGTGCTCGGCGCCGGCGTGATGGGCGCGCAGATCGCCGCGCATCTCGTCAA
TGCGCGCGTGCCCGTGCTGCTGTTCGATCTGCCGGCCAAGGAAGGCCCGAAAAACGGCATCGCGCTGAAGGCGATCGAGA
ACCTGAAGAAGCTGTCGCCCGCGCCGTTCGGCGTGAAGGACGACGCGAAATATCTCGAAGCCGCGAACTACGAGGACGAC
ATCGCGAAGCTCGCCGAATGCGACCTCGTGATCGAGGCGATCGCCGAGCGGATGGACTGGAAGCACGACCTGTACAAGAA
GGTCGCGCCGCACATCACATCGCACGCGATCTTCGCGACCAACACGTCGGGCCTGTCGATCACGACGCTGTCCGACGGCT
TCGCCGACGAGCTGAAGGCGCGCTTCTGCGGCGTGCACTTCTTCAACCCGCCGCGCTACATGCACCTGGTCGAGCTGATC
CCGACCGCGCACACGCGGCCGCAAATCCTCGACCAGCTCGAGACGTTCCTGACGAGCGTCGTCGGCAAGGGCGTCGTGCG
CGCGAAGGACACGCCGAACTTCATCGCGAACCGCGTCGGCATTTTCTCGATCCTCGCCGTGATCACCGAGGCCGAGAAGT
TCGGCCTGCGCTTCGACGAAGTCGACGACCTGACGGGCAGCCGCCTCGGCCGCGCGAAGTCGGCGACGTTCCGCACGGCG
GACGTGGTCGGCCTCGACACGATGGCGCACGTGATCAAGACGATGCAGGACAACCTCGCCGACGATCCGTTCTTCCCGGT
CTACAAGACGCCCGCCGTGCTCGCGAAGCTCGTCGAGCAGGGCGCGCTCGGGCAGAAGACGGGCGGCGGCTTCTACAAGA
AGGAAGGCAAGGCGATCAAGGTGCTCGACGCGAAGACGGGCGCCTATGTCGACTCGGGCGCGAAGGCGGACGAAACCGTC
GGCCGCATCCTGAAGCGCCCGCCCGCCGAGCGCCTGAAGCTGCTGCGCGAGACGCAGCATCCGCATGCGCAGTTCCTGTG
GTCGATCTTCCGCGACGTGTTCCATTACATCGCGTTCCATCTCGAATCGATCGCCGACAACGCGCGTGACGTCGACCTCG
CGATCCGCTGGGGCTTCGGCTGGAACGAAGGTCCGTTCGAGGGCTGGCAGGCCGCGGGCTGGAAGCAGGTTGCCGAGTGG
GTGCAGGAGGACATCGCGGCCGGCCGCGCGCTCGCGAACGTGCCGCTGCCCGCATGGGTGCTCGACGGCGTCGTCGCCGA
GAAGGGCGGCGTGCACACGGCCGAAGGCTCGTGGGCGCCGGCGGCGCAGCGTTTCGCGCCGCGCCCGGATCTCGCCGTCT
ACGACAAGCAGGTGTTCCGCGCGCCCGTGTTCGGCGAAGCGGGGCGCGACCCGAAGACGTTCGGCAAGACGCTGTTCGAG
ACCGACTCGGTGCGCGCATGGGTGGACGACCGCGCGGGCGAGGACGACGTGGTGATCGTGTCGTTCAAGTCGAAGATGAA
CACGATCGGCCCGGGCGTGATCGACGGTCTCGCGCAGGCGATCGAGCTTGCCGAGAAGGACTACAAGGCGGTCGTGATCT
GGCAGCCGAGCTCGCTCAAGCTCGGCAACCCGGGCGGCCCGTTCTCGGCCGGCGCGAACCTCGAAGAGGCGATGCCCGCG
TTCATGATGGGCGGCGCGAAGGGCATCGAGCCGTTCGTGAAGAAGTTCCAGCAAGGCATGCTGCGCGTGAAGTACGCGAA
CGTGCCGGTTGTCGCGGCGGTGTCGGGCCTCGCGCTCGGCGGCGGCTGCGAGCTGATGCTGCATAGCGCGAAGCGCGTGG
TGCACGTCGAGAGCTATATCGGCCTCGTCGAGGTCGGCGTCGGCCTCGTGCCGGCGGGCGGCGGCCTGAAGGAAGCGGCG
CTGCGCGCGGCGGACGCGGCGACGGCGGCGGGCATGACGAGCGAGCTGCTCAAGTTCCTGACGAAGCCGTTCGAGAACGC
GGCGATGGCGAAGGTGTCGATGTCCGCGCACGAAGCGCGCGCGATGGGCTACGTGAAGCCGTCGGACACGATCGTGTTCA
ACGTGTTCGAGCTGCTCGACGTCGCGAAGAAGGAAGCGCGCGGCCTGGCCGCCGCGGGCTACCGCGCGCCGCTGAAGGCG
AAGGAAATCCCGGTGGCGGGCCGCTCGGCGATCGCGACGATCAAGGCGCAACTCGTCAACATGCGCGACGGCCGCTTCAT
CAGCGACCACGATTTCCTGATCGCGAGCCGGATCGCGGAAGCGGTGTGCGGCGGCGACGTCGAGGCGGGCAGCACGGTCG
ACGAGGAATGGCTGCTCGCGCTGGAGCGTCGCGCGTTCGTCGAGCTGCTCGGCACGCAGAAGACGCAGGAACGGATCATG
GGCATGCTGCAGACCGGCAAGCCGGTTCGCAACTGA

Upstream 100 bases:

>100_bases
CCGACAGAGGGGCGCTGCCTTCCCCTGCAAGCAGACGCTGGCACTCATACGCTGCGCGTCCTCACGACCGGCTACGCGCG
GCTCAATCCGGAGGAGTCCC

Downstream 100 bases:

>100_bases
TCGAACCGAGCGGACAACTTTGCATGGGATTGGGGTCGGCGCTGAAATGCCGACTCCGGTCGACCGCCCAAGGACATGGG
ACCAGAGCAGGTGCTGAAGC

Product: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MSNFNIRKVAVLGAGVMGAQIAAHLVNARVPVLLFDLPAKEGPKNGIALKAIENLKKLSPAPFGVKDDAKYLEAANYEDD
IAKLAECDLVIEAIAERMDWKHDLYKKVAPHITSHAIFATNTSGLSITTLSDGFADELKARFCGVHFFNPPRYMHLVELI
PTAHTRPQILDQLETFLTSVVGKGVVRAKDTPNFIANRVGIFSILAVITEAEKFGLRFDEVDDLTGSRLGRAKSATFRTA
DVVGLDTMAHVIKTMQDNLADDPFFPVYKTPAVLAKLVEQGALGQKTGGGFYKKEGKAIKVLDAKTGAYVDSGAKADETV
GRILKRPPAERLKLLRETQHPHAQFLWSIFRDVFHYIAFHLESIADNARDVDLAIRWGFGWNEGPFEGWQAAGWKQVAEW
VQEDIAAGRALANVPLPAWVLDGVVAEKGGVHTAEGSWAPAAQRFAPRPDLAVYDKQVFRAPVFGEAGRDPKTFGKTLFE
TDSVRAWVDDRAGEDDVVIVSFKSKMNTIGPGVIDGLAQAIELAEKDYKAVVIWQPSSLKLGNPGGPFSAGANLEEAMPA
FMMGGAKGIEPFVKKFQQGMLRVKYANVPVVAAVSGLALGGGCELMLHSAKRVVHVESYIGLVEVGVGLVPAGGGLKEAA
LRAADAATAAGMTSELLKFLTKPFENAAMAKVSMSAHEARAMGYVKPSDTIVFNVFELLDVAKKEARGLAAAGYRAPLKA
KEIPVAGRSAIATIKAQLVNMRDGRFISDHDFLIASRIAEAVCGGDVEAGSTVDEEWLLALERRAFVELLGTQKTQERIM
GMLQTGKPVRN

Sequences:

>Translated_811_residues
MSNFNIRKVAVLGAGVMGAQIAAHLVNARVPVLLFDLPAKEGPKNGIALKAIENLKKLSPAPFGVKDDAKYLEAANYEDD
IAKLAECDLVIEAIAERMDWKHDLYKKVAPHITSHAIFATNTSGLSITTLSDGFADELKARFCGVHFFNPPRYMHLVELI
PTAHTRPQILDQLETFLTSVVGKGVVRAKDTPNFIANRVGIFSILAVITEAEKFGLRFDEVDDLTGSRLGRAKSATFRTA
DVVGLDTMAHVIKTMQDNLADDPFFPVYKTPAVLAKLVEQGALGQKTGGGFYKKEGKAIKVLDAKTGAYVDSGAKADETV
GRILKRPPAERLKLLRETQHPHAQFLWSIFRDVFHYIAFHLESIADNARDVDLAIRWGFGWNEGPFEGWQAAGWKQVAEW
VQEDIAAGRALANVPLPAWVLDGVVAEKGGVHTAEGSWAPAAQRFAPRPDLAVYDKQVFRAPVFGEAGRDPKTFGKTLFE
TDSVRAWVDDRAGEDDVVIVSFKSKMNTIGPGVIDGLAQAIELAEKDYKAVVIWQPSSLKLGNPGGPFSAGANLEEAMPA
FMMGGAKGIEPFVKKFQQGMLRVKYANVPVVAAVSGLALGGGCELMLHSAKRVVHVESYIGLVEVGVGLVPAGGGLKEAA
LRAADAATAAGMTSELLKFLTKPFENAAMAKVSMSAHEARAMGYVKPSDTIVFNVFELLDVAKKEARGLAAAGYRAPLKA
KEIPVAGRSAIATIKAQLVNMRDGRFISDHDFLIASRIAEAVCGGDVEAGSTVDEEWLLALERRAFVELLGTQKTQERIM
GMLQTGKPVRN
>Mature_810_residues
SNFNIRKVAVLGAGVMGAQIAAHLVNARVPVLLFDLPAKEGPKNGIALKAIENLKKLSPAPFGVKDDAKYLEAANYEDDI
AKLAECDLVIEAIAERMDWKHDLYKKVAPHITSHAIFATNTSGLSITTLSDGFADELKARFCGVHFFNPPRYMHLVELIP
TAHTRPQILDQLETFLTSVVGKGVVRAKDTPNFIANRVGIFSILAVITEAEKFGLRFDEVDDLTGSRLGRAKSATFRTAD
VVGLDTMAHVIKTMQDNLADDPFFPVYKTPAVLAKLVEQGALGQKTGGGFYKKEGKAIKVLDAKTGAYVDSGAKADETVG
RILKRPPAERLKLLRETQHPHAQFLWSIFRDVFHYIAFHLESIADNARDVDLAIRWGFGWNEGPFEGWQAAGWKQVAEWV
QEDIAAGRALANVPLPAWVLDGVVAEKGGVHTAEGSWAPAAQRFAPRPDLAVYDKQVFRAPVFGEAGRDPKTFGKTLFET
DSVRAWVDDRAGEDDVVIVSFKSKMNTIGPGVIDGLAQAIELAEKDYKAVVIWQPSSLKLGNPGGPFSAGANLEEAMPAF
MMGGAKGIEPFVKKFQQGMLRVKYANVPVVAAVSGLALGGGCELMLHSAKRVVHVESYIGLVEVGVGLVPAGGGLKEAAL
RAADAATAAGMTSELLKFLTKPFENAAMAKVSMSAHEARAMGYVKPSDTIVFNVFELLDVAKKEARGLAAAGYRAPLKAK
EIPVAGRSAIATIKAQLVNMRDGRFISDHDFLIASRIAEAVCGGDVEAGSTVDEEWLLALERRAFVELLGTQKTQERIMG
MLQTGKPVRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=300, Percent_Identity=33.6666666666667, Blast_Score=129, Evalue=9e-30,
Organism=Homo sapiens, GI296179427, Length=315, Percent_Identity=33.015873015873, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI20127408, Length=414, Percent_Identity=26.0869565217391, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI261878539, Length=429, Percent_Identity=24.009324009324, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI68989263, Length=429, Percent_Identity=24.009324009324, Blast_Score=87, Evalue=5e-17,
Organism=Escherichia coli, GI1787661, Length=199, Percent_Identity=35.678391959799, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1790281, Length=228, Percent_Identity=27.6315789473684, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788682, Length=341, Percent_Identity=25.5131964809384, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17553560, Length=296, Percent_Identity=32.7702702702703, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17563036, Length=294, Percent_Identity=31.6326530612245, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17549919, Length=295, Percent_Identity=31.5254237288136, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17558304, Length=389, Percent_Identity=26.4781491002571, Blast_Score=83, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17508953, Length=291, Percent_Identity=29.553264604811, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71985930, Length=413, Percent_Identity=22.2760290556901, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508951, Length=291, Percent_Identity=29.553264604811, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=289, Percent_Identity=29.757785467128, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71985923, Length=300, Percent_Identity=27.3333333333333, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19921000, Length=349, Percent_Identity=26.647564469914, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583077, Length=349, Percent_Identity=26.647564469914, Blast_Score=75, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583079, Length=349, Percent_Identity=26.647564469914, Blast_Score=75, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 87664; Mature: 87533

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFNIRKVAVLGAGVMGAQIAAHLVNARVPVLLFDLPAKEGPKNGIALKAIENLKKLSP
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEHHHHHHHHHCCC
APFGVKDDAKYLEAANYEDDIAKLAECDLVIEAIAERMDWKHDLYKKVAPHITSHAIFAT
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEE
NTSGLSITTLSDGFADELKARFCGVHFFNPPRYMHLVELIPTAHTRPQILDQLETFLTSV
CCCCEEEEEECCCHHHHHHHHHHCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VGKGVVRAKDTPNFIANRVGIFSILAVITEAEKFGLRFDEVDDLTGSRLGRAKSATFRTA
HCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHCCCCCCCCCCHH
DVVGLDTMAHVIKTMQDNLADDPFFPVYKTPAVLAKLVEQGALGQKTGGGFYKKEGKAIK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCEEE
VLDAKTGAYVDSGAKADETVGRILKRPPAERLKLLRETQHPHAQFLWSIFRDVFHYIAFH
EEECCCCCEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LESIADNARDVDLAIRWGFGWNEGPFEGWQAAGWKQVAEWVQEDIAAGRALANVPLPAWV
HHHHHCCCCCEEEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCHHHCCCCHHHH
LDGVVAEKGGVHTAEGSWAPAAQRFAPRPDLAVYDKQVFRAPVFGEAGRDPKTFGKTLFE
HHHHHHCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
TDSVRAWVDDRAGEDDVVIVSFKSKMNTIGPGVIDGLAQAIELAEKDYKAVVIWQPSSLK
CCCHHEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEE
LGNPGGPFSAGANLEEAMPAFMMGGAKGIEPFVKKFQQGMLRVKYANVPVVAAVSGLALG
CCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHEEC
GGCELMLHSAKRVVHVESYIGLVEVGVGLVPAGGGLKEAALRAADAATAAGMTSELLKFL
CCHHHHHHHHHHHEEHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHH
TKPFENAAMAKVSMSAHEARAMGYVKPSDTIVFNVFELLDVAKKEARGLAAAGYRAPLKA
HCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
KEIPVAGRSAIATIKAQLVNMRDGRFISDHDFLIASRIAEAVCGGDVEAGSTVDEEWLLA
CCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
LERRAFVELLGTQKTQERIMGMLQTGKPVRN
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNFNIRKVAVLGAGVMGAQIAAHLVNARVPVLLFDLPAKEGPKNGIALKAIENLKKLSP
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEHHHHHHHHHCCC
APFGVKDDAKYLEAANYEDDIAKLAECDLVIEAIAERMDWKHDLYKKVAPHITSHAIFAT
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEE
NTSGLSITTLSDGFADELKARFCGVHFFNPPRYMHLVELIPTAHTRPQILDQLETFLTSV
CCCCEEEEEECCCHHHHHHHHHHCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VGKGVVRAKDTPNFIANRVGIFSILAVITEAEKFGLRFDEVDDLTGSRLGRAKSATFRTA
HCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHCCCCCCCCCCHH
DVVGLDTMAHVIKTMQDNLADDPFFPVYKTPAVLAKLVEQGALGQKTGGGFYKKEGKAIK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCEEE
VLDAKTGAYVDSGAKADETVGRILKRPPAERLKLLRETQHPHAQFLWSIFRDVFHYIAFH
EEECCCCCEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LESIADNARDVDLAIRWGFGWNEGPFEGWQAAGWKQVAEWVQEDIAAGRALANVPLPAWV
HHHHHCCCCCEEEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCHHHCCCCHHHH
LDGVVAEKGGVHTAEGSWAPAAQRFAPRPDLAVYDKQVFRAPVFGEAGRDPKTFGKTLFE
HHHHHHCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
TDSVRAWVDDRAGEDDVVIVSFKSKMNTIGPGVIDGLAQAIELAEKDYKAVVIWQPSSLK
CCCHHEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEE
LGNPGGPFSAGANLEEAMPAFMMGGAKGIEPFVKKFQQGMLRVKYANVPVVAAVSGLALG
CCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHEEC
GGCELMLHSAKRVVHVESYIGLVEVGVGLVPAGGGLKEAALRAADAATAAGMTSELLKFL
CCHHHHHHHHHHHEEHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHH
TKPFENAAMAKVSMSAHEARAMGYVKPSDTIVFNVFELLDVAKKEARGLAAAGYRAPLKA
HCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
KEIPVAGRSAIATIKAQLVNMRDGRFISDHDFLIASRIAEAVCGGDVEAGSTVDEEWLLA
CCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
LERRAFVELLGTQKTQERIMGMLQTGKPVRN
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]