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The map label for this gene is ctaC [H]

Identifier: 126455009

GI number: 126455009

Start: 471396

End: 472973

Strand: Direct

Name: ctaC [H]

Synonym: BURPS1106A_0507

Alternate gene names: 126455009

Gene position: 471396-472973 (Clockwise)

Preceding gene: 126452399

Following gene: 126454118

Centisome position: 11.82

GC content: 65.97

Gene sequence:

>1578_bases
ATGGAAATTTTGGGTAAGGAAGCTATGAAAACAATCAAGCGAGCCCTCACGGGCGTGCTGGCATGCAGCGCTCTGCTCTT
GTCCGGCGCCGCTCTGGCGGTGGGCGACAGCCCGGGCGGCCCCCGCGTCAACGAGATCAATCTCCAGCCGCCCGTGACGA
AGATCGCCGAGGAGCTCTACGACCTCCACACGATGATGCTGATCCTCTGCACGGTGATCTTCGTCGGCGTGTTCGGCGTG
ATGTTCTATTCGATCTTCGCGCACCGTAAGTCGAAGGGGCACAAGGCCGCCAATTTCCACGAAAGCACCACCGTCGAAAT
CATCTGGACGATCGTGCCGTTCATCATCGTCGTGCTGATGGCGCTGCCCGCCACGAAGGCCGTCGTCGCGATGAAGGACA
CGACGAACGCCGATCTCACGGTGAAGGTCACCGGTTATCAGTGGAAGTGGGGCTACGACTACGTGAAGGGGCCGGGCGAG
GGCATCAGCTTCCTGTCCACGCTGTCGACGCCGCGCACCGAAGTGAACGGCCGGCAGCCGATCAGCGATACCTACCTGCA
GGAAGTCGATCACCCGCTCGTCGTGCCGGTCAACAAGAAGATCCGCGTGATCACGACCGCGAACGACGTCGTCCACTCGT
GGTACGTCCCGGCGTTCGGCGTCAAGCAGGATGCGATTCCGGGCTTCGTGCGCGACACCTGGTTCAAGGCCGAGAAGGTC
GGCACCTACCGCGGCTTCTGCACGGAGCTCTGCGGCAAGGAGCACGCGTACATGCCGGTCGTCGTCGAGGTGCTGTCGGA
CGACGATTACGCGAAGTGGGTGAGCACGCAGAAGGCGAAGCTCGCCGCAGGCGCGGTCGATCCGAACAAGGTGTATACGC
GCGCCGAGCTGATGGCGCACGGCGAGGAAGTCTACAAGGCGAACTGCGCGGCGTGCCACCAGCCGAACGGCAAGGGCGTC
GGCGCGTTCCCCGCGCTCGATGGCGGCAAGATCGTCAACGGCCCGATCGCCGGCCATCTCGAGCAGGTGCTCAAGGGCAA
GGGCGCGATGCCGTCGTGGGCGTCGCTGTCGGATCTCGACATCGCGTCGGTGATCACGTACGAGCGCAACTCGTGGGGCA
ACCACAAGGGCGATTCGCTGCAGCCGAAGCAGGTGGCCGACGCGCGCAACGGCAAGCTGCCGGAAGACGCGCAGCAGGCC
GACGGCGGCGCGGCGGCTAACGCCGCCTCGGGCGCGGCCGCGCAGACGCAGGCGCAAGCACCGGCGTTGCCGGCCGCCAT
CTATTTCGAGACGGGCAAGAGCGAGCTGCCGGCGGACGCGAAGGACGCGATCGCCGCGGCGGCCGAATACGTGAAGGCGC
ATCCGGACGCGAAGCTCGCGTTGTCGGGCTTCACCGACAAGACGGGCTCGGCCGACGCGAACGCCGAACTGGCCAAGCGC
CGCGCACAGGTCGTGCGCGATGCGCTGAAGACGGCCGGCGTCGCGGAGGACCGCATCATTCTGAAGAAGCCGGAAACGAT
CACGGGCGGGGCGGACGCGAAGGAAGCCCGGCGGGTCGAGATCGGCCCGGCGGCTTGA

Upstream 100 bases:

>100_bases
CGCGCGCAGTTCGCGCGCGAGCTGCGCGCCTCGCTTTCGCGCTACGGCTGAACGAGGCGGCCGGCGCGAAGCGGGCGACC
TGCGACGGGGGAGGGTTTGA

Downstream 100 bases:

>100_bases
CGTGTCGCTGTGTTTGTCGACGTATTCGCATTAGGAGATTCTCATGTCTAGCATCGGGCACGACGTAGCCGCGGGCCACG
CGCACGACGACCACGCGCAC

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MEILGKEAMKTIKRALTGVLACSALLLSGAALAVGDSPGGPRVNEINLQPPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLMALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGE
GISFLSTLSTPRTEVNGRQPISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKAEKV
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSTQKAKLAAGAVDPNKVYTRAELMAHGEEVYKANCAACHQPNGKGV
GAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLDIASVITYERNSWGNHKGDSLQPKQVADARNGKLPEDAQQA
DGGAAANAASGAAAQTQAQAPALPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAELAKR
RAQVVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA

Sequences:

>Translated_525_residues
MEILGKEAMKTIKRALTGVLACSALLLSGAALAVGDSPGGPRVNEINLQPPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLMALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGE
GISFLSTLSTPRTEVNGRQPISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKAEKV
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSTQKAKLAAGAVDPNKVYTRAELMAHGEEVYKANCAACHQPNGKGV
GAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLDIASVITYERNSWGNHKGDSLQPKQVADARNGKLPEDAQQA
DGGAAANAASGAAAQTQAQAPALPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAELAKR
RAQVVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA
>Mature_525_residues
MEILGKEAMKTIKRALTGVLACSALLLSGAALAVGDSPGGPRVNEINLQPPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLMALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGE
GISFLSTLSTPRTEVNGRQPISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKAEKV
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSTQKAKLAAGAVDPNKVYTRAELMAHGEEVYKANCAACHQPNGKGV
GAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLDIASVITYERNSWGNHKGDSLQPKQVADARNGKLPEDAQQA
DGGAAANAASGAAAQTQAQAPALPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAELAKR
RAQVVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=221, Percent_Identity=34.841628959276, Blast_Score=137, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6226540, Length=233, Percent_Identity=30.4721030042918, Blast_Score=126, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 55948; Mature: 55948

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILGKEAMKTIKRALTGVLACSALLLSGAALAVGDSPGGPRVNEINLQPPVTKIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEECCCCCHHHHHHHHH
DLHTMMLILCTVIFVGVFGVMFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGEGISFLSTLSTPRTEVNGRQP
HCCCCCEEEEEECCCCCEEEEEEECEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
ISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKAEKV
CHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSTQKAKLAAGAVDPNKVYTRAELMAH
CCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
GEEVYKANCAACHQPNGKGVGAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLD
CHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCCC
IASVITYERNSWGNHKGDSLQPKQVADARNGKLPEDAQQADGGAAANAASGAAAQTQAQA
HHHHEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHCCC
PALPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAELAKR
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHH
RAQVVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure
MEILGKEAMKTIKRALTGVLACSALLLSGAALAVGDSPGGPRVNEINLQPPVTKIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEECCCCCHHHHHHHHH
DLHTMMLILCTVIFVGVFGVMFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGEGISFLSTLSTPRTEVNGRQP
HCCCCCEEEEEECCCCCEEEEEEECEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
ISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKAEKV
CHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSTQKAKLAAGAVDPNKVYTRAELMAH
CCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
GEEVYKANCAACHQPNGKGVGAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLD
CHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCCC
IASVITYERNSWGNHKGDSLQPKQVADARNGKLPEDAQQADGGAAANAASGAAAQTQAQA
HHHHEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHCCC
PALPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAELAKR
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHH
RAQVVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1648008 [H]