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The map label for this gene is ctaD [H]

Identifier: 126454118

GI number: 126454118

Start: 473017

End: 474624

Strand: Direct

Name: ctaD [H]

Synonym: BURPS1106A_0508

Alternate gene names: 126454118

Gene position: 473017-474624 (Clockwise)

Preceding gene: 126455009

Following gene: 126454049

Centisome position: 11.86

GC content: 64.61

Gene sequence:

>1608_bases
ATGTCTAGCATCGGGCACGACGTAGCCGCGGGCCACGCGCACGACGACCACGCGCACGAAACCCCGCACGGCTGGCGGCG
CTGGCTGTTCGCCACCAACCACAAGGATATCGGTACGCTGTACCTGCTGTTCTCGTTCATCATGTTCCTGTCGGGCGGCG
TGATGGCGCTCGCGATTCGCGCCGAGCTGTTCGAGCCGGGCCTGCAGATCATGCGGCCCGAGTTCTTCAATCAGCTCACG
ACGATGCACGGGCTGATCATGGTGTTCGGCGCGATCATGCCGGCCTTCGTCGGTTTCGCGAACTGGATGATTCCGCTGCA
GATCGGCGCGTCGGACATGGCGTTCGCGCGGATGAACAATTTCAGCTTCTGGCTGCTGCCGGTGGCGGCGGTGCTGCTCG
TCGGCTCGTTCTTCTCGCCGGGCGGCGCGACGGCCGCCGGCTGGACGCTGTATGCGCCGCTGTCGACGCAGATGGGCCCG
GGCATGGACTTCGCGATCTTCGCGGTGCACATCATGGGCGCGTCGTCGATCATGGGCGGGATCAACATCGTCGTGACGAT
CCTGAACATGCGCGCGCCGGGCATGACGCTGATGAAGATGCCGATGTTCGCGTGGACGTGGCTCATCACCGCGTACCTGC
TGATCGCCGTGATGCCGGTTCTGGCGGGCGCGATCACGATGGTGCTGTTCGACCGTCACTTCGGCACGTCGTTCTTCAAC
GCGGCGGGCGGCGGCGATCCGGTGATGTATCAGCACATCTTCTGGTTCTTCGGCCACCCCGAGGTGTACATCATGATTCT
GCCGGCGTTCGGGATCGTGTCGCAGGTGATCCCGGCGTTCGCGCGCAAGCCGCTCTTCGGCTACAGCTCGATGGTGTACG
CGACCGCGTCGATCGCGATCCTGTCGTTCATGGTCTGGGCGCACCACATGTTCGTGACCGGCATGCCGGTGACGGGCCAG
CTGTTCTTCATGTACGCGACGATGCTGATCGCGGTGCCGACGGGCGTGAAGGTGTTCAACTGGCTCGCGACGATGTGGCG
CGGCTCGCTCACGTTCGAGACGCCGATGCTGTTCGCGATCGGCTTCCTGTTCGTGTTCACGATGGGCGGCTTCACGGGCC
TGATGCTCGCGATGGCGCCGCTCGACATCCAGTACCACGGTACGTACTTCGTCGTCGCGCACTTCCATTACGTGCTCGTC
GCGGGGTCGCTGTTCGCGCTCTTCGCCGGCTGGTACTACTGGGCGCCGAAATGGACCGGCTGGATGTACAACGAGACGCG
CGGGAAGATCCACTTCTGGGCGTCGATGATCTTCTTCAACGTCACGTTCTTCCCGATGCACTTCGTCGGCCTCGCGGGCA
TGCCGCGCCGCTATGCGGACTACCCGGCGCAGTTCACCGATTTCAACCAGCTCGCGACGATCGGCGCATTCGGCTTCGGC
CTCGCGCAGGTGTACTTCCTGTTCGCGATCGTGCTGCCCGCGTATCGCGGCGGCGGCGAGCTCGAGCGCGCATCCGACAA
GCCGTGGGACGGCGCGACGGGCCTCGAGTGGACGGTGCCGAGCCCGGCTCCGTTCCACACGTTCGAGCATCCGCCGACGG
TCGAGTAA

Upstream 100 bases:

>100_bases
ACGGGCGGGGCGGACGCGAAGGAAGCCCGGCGGGTCGAGATCGGCCCGGCGGCTTGACGTGTCGCTGTGTTTGTCGACGT
ATTCGCATTAGGAGATTCTC

Downstream 100 bases:

>100_bases
TGATTTGACGGCGTTCGCCGCCCGTGTCGTACGACGCGGGCGGCGCACACCCGAACGAAAAAATTCGCATGACCCGGAAT
TCACAAAAAAGACGAACGCC

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MSSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIRAELFEPGLQIMRPEFFNQLT
TMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFSPGGATAAGWTLYAPLSTQMGP
GMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASIAILSFMVWAHHMFVTGMPVTGQ
LFFMYATMLIAVPTGVKVFNWLATMWRGSLTFETPMLFAIGFLFVFTMGGFTGLMLAMAPLDIQYHGTYFVVAHFHYVLV
AGSLFALFAGWYYWAPKWTGWMYNETRGKIHFWASMIFFNVTFFPMHFVGLAGMPRRYADYPAQFTDFNQLATIGAFGFG
LAQVYFLFAIVLPAYRGGGELERASDKPWDGATGLEWTVPSPAPFHTFEHPPTVE

Sequences:

>Translated_535_residues
MSSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIRAELFEPGLQIMRPEFFNQLT
TMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFSPGGATAAGWTLYAPLSTQMGP
GMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASIAILSFMVWAHHMFVTGMPVTGQ
LFFMYATMLIAVPTGVKVFNWLATMWRGSLTFETPMLFAIGFLFVFTMGGFTGLMLAMAPLDIQYHGTYFVVAHFHYVLV
AGSLFALFAGWYYWAPKWTGWMYNETRGKIHFWASMIFFNVTFFPMHFVGLAGMPRRYADYPAQFTDFNQLATIGAFGFG
LAQVYFLFAIVLPAYRGGGELERASDKPWDGATGLEWTVPSPAPFHTFEHPPTVE
>Mature_534_residues
SSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIRAELFEPGLQIMRPEFFNQLTT
MHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFSPGGATAAGWTLYAPLSTQMGPG
MDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFNA
AGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASIAILSFMVWAHHMFVTGMPVTGQL
FFMYATMLIAVPTGVKVFNWLATMWRGSLTFETPMLFAIGFLFVFTMGGFTGLMLAMAPLDIQYHGTYFVVAHFHYVLVA
GSLFALFAGWYYWAPKWTGWMYNETRGKIHFWASMIFFNVTFFPMHFVGLAGMPRRYADYPAQFTDFNQLATIGAFGFGL
AQVYFLFAIVLPAYRGGGELERASDKPWDGATGLEWTVPSPAPFHTFEHPPTVE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=48.7279843444227, Blast_Score=456, Evalue=1e-128,
Organism=Escherichia coli, GI1786634, Length=521, Percent_Identity=41.2667946257198, Blast_Score=382, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=47.834274952919, Blast_Score=490, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=50.4643962848297, Blast_Score=333, Evalue=4e-92,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=46.9635627530364, Blast_Score=216, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59530; Mature: 59399

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIR
CCCCCCCHHCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCHHEEHHH
AELFEPGLQIMRPEFFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNN
HHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCC
FSFWLLPVAAVLLVGSFFSPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIMGG
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
INIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
HHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASIAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LSFMVWAHHMFVTGMPVTGQLFFMYATMLIAVPTGVKVFNWLATMWRGSLTFETPMLFAI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
GFLFVFTMGGFTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFAGWYYWAPKWTG
HHHHHHHHCCHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
WMYNETRGKIHFWASMIFFNVTFFPMHFVGLAGMPRRYADYPAQFTDFNQLATIGAFGFG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LAQVYFLFAIVLPAYRGGGELERASDKPWDGATGLEWTVPSPAPFHTFEHPPTVE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIR
CCCCCCHHCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCHHEEHHH
AELFEPGLQIMRPEFFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNN
HHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCC
FSFWLLPVAAVLLVGSFFSPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIMGG
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
INIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
HHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASIAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LSFMVWAHHMFVTGMPVTGQLFFMYATMLIAVPTGVKVFNWLATMWRGSLTFETPMLFAI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
GFLFVFTMGGFTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFAGWYYWAPKWTG
HHHHHHHHCCHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
WMYNETRGKIHFWASMIFFNVTFFPMHFVGLAGMPRRYADYPAQFTDFNQLATIGAFGFG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LAQVYFLFAIVLPAYRGGGELERASDKPWDGATGLEWTVPSPAPFHTFEHPPTVE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]