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The map label for this gene is serC [H]

Identifier: 126454949

GI number: 126454949

Start: 2892971

End: 2894053

Strand: Reverse

Name: serC [H]

Synonym: BURPS1106A_2949

Alternate gene names: 126454949

Gene position: 2894053-2892971 (Counterclockwise)

Preceding gene: 126453782

Following gene: 126451838

Centisome position: 72.56

GC content: 64.27

Gene sequence:

>1083_bases
ATGCGCGTCTTTAATTTCTCCGCCGGCCCCGCGGCGATGCCCGAGGAAGTGCTGCGCCAGGCGGCCGCCGAAATGCTCGA
CTGGAACGGCAGCGGCATGAGCGTGATGGAAATGAGCCATCGCGGCAAGGAATTCATGTCGATTCACGAGGCCGCGCTTG
CCGACCTGCGCGAATTGCTCGGTGTGCCCGCGAACTACCGGATCCTGTTCCTGCAGGGCGGGGGGATCGCCGAGAATGCG
ATCGTGCCGATGAACCTGCTCGGCTCGCGCACGACCGCCGATTTCGTCATCACGGGCTCGTGGTCGCAGAAATCGTTCAA
CGAGGCGAAGAAGTACTGCGTGCCGCATCTGGCCGCGACGGGCAAGACGGACGCGGGCTTCACGCGCGTGCCGGCGTTCT
CCGAATGGCGGATGTCGGACGATCCGGCGTACGTGCACCTGTGCACGAACGAGACGATCGACGGCGTCGAGACGTTCGAC
ATCCCCGATCTCGGCAACGTGCCGCTCGTCGCCGACGTGTCGTCGCACATCCTGTCGCGTCCGATCGAGATCGAGAAGTA
CGGCGCGATCTTCGGCGGCGCGCAGAAGAACATCGGGATGGCGGGCGTGACGCTCGTGATCGTGCGCGAGGATCTGCTCG
ATCGCGCGCTGTCGATCTGCCCGTCGGCGTTCGAATGGAAGACGGTCGCGCTCAACAATTCGCTCTACAACACGCCGCCC
ACCTATGCGATCTACATCGCGGGCCTCGTGTTCAAGTGGCTGAAGGCGCAGGGCGGCCTGGCCGCGATCGAGGCGCGCAA
CATCGAAAAATCGAAGCTGCTGTACGACGCGATCGACGCGAGCGGCTTCTATCTGAACAAGGTCGAGAAGCCGGCGCGTT
CGCGGATGAACGTGCCGTTCTTCCTCGCCGACGAATCGCGCAACGAAGACTTCCTTGCCGGCGCAAAAGAGCGCGGGCTG
CTGCAGTTGAAGGGCCACAAGTCCGTCGGCGGCATGCGGGCGTCGATCTACAACGCGGTGCCGCTCGCGGGCGTGCAGGC
GCTCGTCGAGTACATGAAGGATTTCGAGCGGCGCTGCGCGTGA

Upstream 100 bases:

>100_bases
GATAATGGCCGTTTGCGCGACAGCGCAAGCGGCCATTTCCTTTTCCCGCGCGGCATTCGGCCGGTTCGAAGCGGCCGGGT
CCCTTCCGAGGTTTTTCACG

Downstream 100 bases:

>100_bases
CGCGCGCCGCTCCTTACGCATTGTTGGTCAAGTCATGGACGACGAACTCAATTCCCGCCTGAAGCCTCTGCGCGAGCGCA
TCGACGCGATCGACACGCAA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRVFNFSAGPAAMPEEVLRQAAAEMLDWNGSGMSVMEMSHRGKEFMSIHEAALADLRELLGVPANYRILFLQGGGIAENA
IVPMNLLGSRTTADFVITGSWSQKSFNEAKKYCVPHLAATGKTDAGFTRVPAFSEWRMSDDPAYVHLCTNETIDGVETFD
IPDLGNVPLVADVSSHILSRPIEIEKYGAIFGGAQKNIGMAGVTLVIVREDLLDRALSICPSAFEWKTVALNNSLYNTPP
TYAIYIAGLVFKWLKAQGGLAAIEARNIEKSKLLYDAIDASGFYLNKVEKPARSRMNVPFFLADESRNEDFLAGAKERGL
LQLKGHKSVGGMRASIYNAVPLAGVQALVEYMKDFERRCA

Sequences:

>Translated_360_residues
MRVFNFSAGPAAMPEEVLRQAAAEMLDWNGSGMSVMEMSHRGKEFMSIHEAALADLRELLGVPANYRILFLQGGGIAENA
IVPMNLLGSRTTADFVITGSWSQKSFNEAKKYCVPHLAATGKTDAGFTRVPAFSEWRMSDDPAYVHLCTNETIDGVETFD
IPDLGNVPLVADVSSHILSRPIEIEKYGAIFGGAQKNIGMAGVTLVIVREDLLDRALSICPSAFEWKTVALNNSLYNTPP
TYAIYIAGLVFKWLKAQGGLAAIEARNIEKSKLLYDAIDASGFYLNKVEKPARSRMNVPFFLADESRNEDFLAGAKERGL
LQLKGHKSVGGMRASIYNAVPLAGVQALVEYMKDFERRCA
>Mature_360_residues
MRVFNFSAGPAAMPEEVLRQAAAEMLDWNGSGMSVMEMSHRGKEFMSIHEAALADLRELLGVPANYRILFLQGGGIAENA
IVPMNLLGSRTTADFVITGSWSQKSFNEAKKYCVPHLAATGKTDAGFTRVPAFSEWRMSDDPAYVHLCTNETIDGVETFD
IPDLGNVPLVADVSSHILSRPIEIEKYGAIFGGAQKNIGMAGVTLVIVREDLLDRALSICPSAFEWKTVALNNSLYNTPP
TYAIYIAGLVFKWLKAQGGLAAIEARNIEKSKLLYDAIDASGFYLNKVEKPARSRMNVPFFLADESRNEDFLAGAKERGL
LQLKGHKSVGGMRASIYNAVPLAGVQALVEYMKDFERRCA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=47.6454293628809, Blast_Score=340, Evalue=1e-93,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=43.1372549019608, Blast_Score=290, Evalue=1e-78,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=54.7486033519553, Blast_Score=407, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=46.9613259668508, Blast_Score=341, Evalue=4e-94,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=41.1917098445596, Blast_Score=282, Evalue=6e-77,
Organism=Drosophila melanogaster, GI21356589, Length=367, Percent_Identity=49.3188010899183, Blast_Score=362, Evalue=1e-100,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39426; Mature: 39426

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFNFSAGPAAMPEEVLRQAAAEMLDWNGSGMSVMEMSHRGKEFMSIHEAALADLRELL
CEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHH
GVPANYRILFLQGGGIAENAIVPMNLLGSRTTADFVITGSWSQKSFNEAKKYCVPHLAAT
CCCCCCEEEEEECCCCCCCCEECHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCC
GKTDAGFTRVPAFSEWRMSDDPAYVHLCTNETIDGVETFDIPDLGNVPLVADVSSHILSR
CCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCEEHHHHHHHHHC
PIEIEKYGAIFGGAQKNIGMAGVTLVIVREDLLDRALSICPSAFEWKTVALNNSLYNTPP
CCCEEHHCCEECCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
TYAIYIAGLVFKWLKAQGGLAAIEARNIEKSKLLYDAIDASGFYLNKVEKPARSRMNVPF
HHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEHHHHCCHHHHCCCCCE
FLADESRNEDFLAGAKERGLLQLKGHKSVGGMRASIYNAVPLAGVQALVEYMKDFERRCA
EEECCCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVFNFSAGPAAMPEEVLRQAAAEMLDWNGSGMSVMEMSHRGKEFMSIHEAALADLRELL
CEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHH
GVPANYRILFLQGGGIAENAIVPMNLLGSRTTADFVITGSWSQKSFNEAKKYCVPHLAAT
CCCCCCEEEEEECCCCCCCCEECHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCC
GKTDAGFTRVPAFSEWRMSDDPAYVHLCTNETIDGVETFDIPDLGNVPLVADVSSHILSR
CCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCEEHHHHHHHHHC
PIEIEKYGAIFGGAQKNIGMAGVTLVIVREDLLDRALSICPSAFEWKTVALNNSLYNTPP
CCCEEHHCCEECCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
TYAIYIAGLVFKWLKAQGGLAAIEARNIEKSKLLYDAIDASGFYLNKVEKPARSRMNVPF
HHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEHHHHCCHHHHCCCCCE
FLADESRNEDFLAGAKERGLLQLKGHKSVGGMRASIYNAVPLAGVQALVEYMKDFERRCA
EEECCCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA