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The map label for this gene is intS [H]

Identifier: 126454671

GI number: 126454671

Start: 3620175

End: 3621005

Strand: Reverse

Name: intS [H]

Synonym: BURPS1106A_3701

Alternate gene names: 126454671

Gene position: 3621005-3620175 (Counterclockwise)

Preceding gene: 126453519

Following gene: 126454628

Centisome position: 90.79

GC content: 60.17

Gene sequence:

>831_bases
ATGCCGTTGACCGACGTCGCGATTCGTAAAGCCGCTCCGCGCGAAAAGCCGTACCGCCTTGCTGATAGCGGCGGTATGTA
CCTCGAGGTTTCGCCGGCCGGCGGGAAATACTGGCGGCTCAAATACCGTTTCCTGGGCAAGGAGAAGCGGCTTGCGTTGG
GCGTCTACCCGGACGTGTCGTTAGCTGCTGCTCGGGAGAAGCGTGATGATGCCCGAAAGAAGCTCGCCGCCGGTGTCGAT
CCCAGCGAAGCGAAGAAGGCTGATAAGCGTGCTGCACGCCTTGCCGCAACTAATTCGTTCGAGGCCGTTGCTCTTGGCTG
GATGGATGAACTCAAGCCGTACGTTACGGCCGGGTCGATGGCGAAGACCAAGGCTCGCTTCGAGAAGGACGTGTTCCCGT
GGATAGGCAAACGGCCGGTAGCGGAAATCGATGCGCCCGAAATCTTGACGGTTCTCAAGCGGATCGACAGTCGCGGCGCT
CGCTTCACAGCCCACAAGGTTCGCGGCGAGATCAGCCGCGCATTCCGCTACGGAATCAAGGAAGGCTATTGTAAGTTTGA
TCCGGCTCGCGATCTGGTCAATGCCATCCCGCCGGCGCAGACGACCCACTTTGCTTCGATTACGGAGCCGGCGAAGGTTG
GCGCCATGCTTCGGGCATTCGATGGCTTTTCCGGCACGTTTCCTGTCCTCTGCGCGCTCAAGCTCGCGCCCATGTTGTTC
ACGCGCCCCGGCGAGTTGCGCAAGGCCGAGTGGGCTCAGTTCGATCTTGATAAGGGCGAGTGGCGGTACCTTGTCACGAA
AACCTCAACCGAGCATCTAGCAGGCTGTTGA

Upstream 100 bases:

>100_bases
CTGAATCCGGGGGCATGTGGGGGCACCACCGGGGGAATCACCGCAATCTGGCAAAGGCCCCCGGGAAAAGTGCCCCCTAG
CGCTGTAAGGTAGATGCCTT

Downstream 100 bases:

>100_bases
AAAGCGCCTCGTTTTGACGGCCGGGGCACTGTTTAAAAGGGTTGCGTATGCGATTGGCCGCTGAGTTGCAGATGGATCGT
GCCGGACGTCTCGCTGGCGA

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MPLTDVAIRKAAPREKPYRLADSGGMYLEVSPAGGKYWRLKYRFLGKEKRLALGVYPDVSLAAAREKRDDARKKLAAGVD
PSEAKKADKRAARLAATNSFEAVALGWMDELKPYVTAGSMAKTKARFEKDVFPWIGKRPVAEIDAPEILTVLKRIDSRGA
RFTAHKVRGEISRAFRYGIKEGYCKFDPARDLVNAIPPAQTTHFASITEPAKVGAMLRAFDGFSGTFPVLCALKLAPMLF
TRPGELRKAEWAQFDLDKGEWRYLVTKTSTEHLAGC

Sequences:

>Translated_276_residues
MPLTDVAIRKAAPREKPYRLADSGGMYLEVSPAGGKYWRLKYRFLGKEKRLALGVYPDVSLAAAREKRDDARKKLAAGVD
PSEAKKADKRAARLAATNSFEAVALGWMDELKPYVTAGSMAKTKARFEKDVFPWIGKRPVAEIDAPEILTVLKRIDSRGA
RFTAHKVRGEISRAFRYGIKEGYCKFDPARDLVNAIPPAQTTHFASITEPAKVGAMLRAFDGFSGTFPVLCALKLAPMLF
TRPGELRKAEWAQFDLDKGEWRYLVTKTSTEHLAGC
>Mature_275_residues
PLTDVAIRKAAPREKPYRLADSGGMYLEVSPAGGKYWRLKYRFLGKEKRLALGVYPDVSLAAAREKRDDARKKLAAGVDP
SEAKKADKRAARLAATNSFEAVALGWMDELKPYVTAGSMAKTKARFEKDVFPWIGKRPVAEIDAPEILTVLKRIDSRGAR
FTAHKVRGEISRAFRYGIKEGYCKFDPARDLVNAIPPAQTTHFASITEPAKVGAMLRAFDGFSGTFPVLCALKLAPMLFT
RPGELRKAEWAQFDLDKGEWRYLVTKTSTEHLAGC

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788690, Length=257, Percent_Identity=36.1867704280156, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1788974, Length=263, Percent_Identity=29.6577946768061, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI145693166, Length=258, Percent_Identity=31.0077519379845, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 30671; Mature: 30540

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTDVAIRKAAPREKPYRLADSGGMYLEVSPAGGKYWRLKYRFLGKEKRLALGVYPDVS
CCCCHHHHHHCCCCCCCCEEECCCCEEEEEECCCCCEEEEEEEECCCCCCEEEECCCCCH
LAAAREKRDDARKKLAAGVDPSEAKKADKRAARLAATNSFEAVALGWMDELKPYVTAGSM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHH
AKTKARFEKDVFPWIGKRPVAEIDAPEILTVLKRIDSRGARFTAHKVRGEISRAFRYGIK
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHH
EGYCKFDPARDLVNAIPPAQTTHFASITEPAKVGAMLRAFDGFSGTFPVLCALKLAPMLF
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TRPGELRKAEWAQFDLDKGEWRYLVTKTSTEHLAGC
CCCCCCCCCHHHEECCCCCCEEEEEEECCHHHHCCC
>Mature Secondary Structure 
PLTDVAIRKAAPREKPYRLADSGGMYLEVSPAGGKYWRLKYRFLGKEKRLALGVYPDVS
CCCHHHHHHCCCCCCCCEEECCCCEEEEEECCCCCEEEEEEEECCCCCCEEEECCCCCH
LAAAREKRDDARKKLAAGVDPSEAKKADKRAARLAATNSFEAVALGWMDELKPYVTAGSM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHH
AKTKARFEKDVFPWIGKRPVAEIDAPEILTVLKRIDSRGARFTAHKVRGEISRAFRYGIK
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHH
EGYCKFDPARDLVNAIPPAQTTHFASITEPAKVGAMLRAFDGFSGTFPVLCALKLAPMLF
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TRPGELRKAEWAQFDLDKGEWRYLVTKTSTEHLAGC
CCCCCCCCCHHHEECCCCCCEEEEEEECCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]