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The map label for this gene is sir [H]

Identifier: 126454547

GI number: 126454547

Start: 989859

End: 991538

Strand: Direct

Name: sir [H]

Synonym: BURPS1106A_1013

Alternate gene names: 126454547

Gene position: 989859-991538 (Clockwise)

Preceding gene: 126453597

Following gene: 126452080

Centisome position: 24.82

GC content: 65.6

Gene sequence:

>1680_bases
ATGTACCAGTACGACCAATACGATCAGACGATCGTCGACGAGCGCGTCGCGCAGTACCGCGACCAGGTCCGCCGCCGCTT
GTCCGGCGAATTGAGCGAGGACGAGTTCCGTCCGCTGCGGCTGCAGAACGGCCTGTACATGCAGCGCCACGCCTACATGC
ACCGCATCGCGATTCCCTACGGCAATCTCCGTAGCGTCCAGCTGCGCATGCTCGCCCGCATCGCGCGCGAGCACGATCGC
GGCTACGGCCATTTCTCGACGCGCTCGAATATCCAGTACAACTGGGTGAAGCTCGAGGAAACGCCCGAGATTCTCGCAAA
GCTCGCGTCGGTGCAGATGCACGCGATCCAGACCTCGGGCAACTGCATCCGCAACATCACGGCCGACCAGTTCGCGGGCG
TGGCTCAGGACGAGGAGCTCGATCCGCGTCCGTGGGCCGAGATCCTGCGCCAGTGGTCGACCTTCCATCCCGAATTCGCA
TGGCTGCCGCGCAAGTTCAAGATCGCGGTGTCCGGCTCGAAGGCCGATCGCGCCGCCGTGCAGATCCACGATCTCGGCGT
CTACCTGAAGAAGAACGACGCGGGCGAAGTGGTCGCGAGCATTCTCGCGGGCGGTGGTCTCGGCCGCACGCCGATCGTCG
GCGCGATTATCCGCGAGAATCTGCCGTGGCAGCATCTGCTCACTTACTGCGAGGCGGTGCTGCGCGTCTACAATCGTTAT
GGCCGCCGCGACAACCTGTACAAGGCGCGGATCAAGATCCTCGTGAAGGCGCTGTCGCCCGCGAAGTTCGCGCAACAGGT
CGAAGCGGAGTGGCAGCACCTGAAGGACGGCCCGTCCACGCTCACGCAGGCCGAACTCGAGCGCGTGTCGCAGTTCTTCC
AGCCGCCCGCCTATGAGAAGCTTGCCGATACCGACGCGTCGTTCGAGCAGCATCTGCTCGAGAACCGCGCGTTCGCGCGC
TGGGTCGAGCGCAACGTCGCGCCGCACAAGGTGCCGGGCTATGCGGCCGTCACGCTGTCGTTGAAGAACCACCGCGTCGC
GCCCGGCGACGCGAGCGCCGAGCAGATGGAGCAGGTCGCCGACTGGGCCGACGCCTATTCGTTCGGCGAGCTGCGCGTGT
CGCACGAACAGAACCTGATTCTCGCGAACGTGAAGAAGCGCGACCTGTTCGCAGTATGGGAAAAGGCGAAGGCGGCCGGT
TTCGCGACGCCGAACGTCGGCTTGCTGACCGACATCATCGCGTGCCCGGGGGGCGACTTCTGCTCGCTCGCGAACGCGAA
GTCGATCCCGATCGCGCTCGCGATCCAGCAGCGCTTCGACGATCTCGACTACGTGTACGACCTGGGCGACGTGTCGCTCA
ACATCTCGGGCTGCATGAACTCGTGCGGGCACCACCACATCGGCAACATCGGCATCCTCGGCGTCGACAAGGACGGCGCG
GAGTGGTATCAGGTGTCGCTCGGCGGCGAGCAGGGCACGGCAGCGGGCGGCGCGCGCCTCGGCCGCGTGATCGGCCCGTC
GTTCTCGGCCGAGGAAGTGCCCGACGTGATCTCGAAGCTGATCGACACGTTCGTCGAATCGCGCATCGACGGCGAGCGCT
TCATCGACACGTACGAGCGCATCGGCATCGCGCCGTTCAAGGAGCGCGTCTACGCGGCGCGCCAGACCGCGCACGCGTAA

Upstream 100 bases:

>100_bases
GGCCGGGCGGATGGTCGGCTCGGCGCGGGCGGTGCAGGATTCGGGCGCGGCGTGGCTAGGACGCCGCGCGGTCATATCGA
GCAAACCCTGGGGTCCCCGA

Downstream 100 bases:

>100_bases
CACCCAGCGTAGAGGAATCAGCAGATGGCTTTGATTATCAAGAATCGCGAAGTGGTCGACGACGCGTGGCAACTCGTGCG
CGCGGCCGAAGACGGCACGC

Product: sulfite reductase, ferredoxin subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEDEFRPLRLQNGLYMQRHAYMHRIAIPYGNLRSVQLRMLARIAREHDR
GYGHFSTRSNIQYNWVKLEETPEILAKLASVQMHAIQTSGNCIRNITADQFAGVAQDEELDPRPWAEILRQWSTFHPEFA
WLPRKFKIAVSGSKADRAAVQIHDLGVYLKKNDAGEVVASILAGGGLGRTPIVGAIIRENLPWQHLLTYCEAVLRVYNRY
GRRDNLYKARIKILVKALSPAKFAQQVEAEWQHLKDGPSTLTQAELERVSQFFQPPAYEKLADTDASFEQHLLENRAFAR
WVERNVAPHKVPGYAAVTLSLKNHRVAPGDASAEQMEQVADWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAG
FATPNVGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGDVSLNISGCMNSCGHHHIGNIGILGVDKDGA
EWYQVSLGGEQGTAAGGARLGRVIGPSFSAEEVPDVISKLIDTFVESRIDGERFIDTYERIGIAPFKERVYAARQTAHA

Sequences:

>Translated_559_residues
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEDEFRPLRLQNGLYMQRHAYMHRIAIPYGNLRSVQLRMLARIAREHDR
GYGHFSTRSNIQYNWVKLEETPEILAKLASVQMHAIQTSGNCIRNITADQFAGVAQDEELDPRPWAEILRQWSTFHPEFA
WLPRKFKIAVSGSKADRAAVQIHDLGVYLKKNDAGEVVASILAGGGLGRTPIVGAIIRENLPWQHLLTYCEAVLRVYNRY
GRRDNLYKARIKILVKALSPAKFAQQVEAEWQHLKDGPSTLTQAELERVSQFFQPPAYEKLADTDASFEQHLLENRAFAR
WVERNVAPHKVPGYAAVTLSLKNHRVAPGDASAEQMEQVADWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAG
FATPNVGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGDVSLNISGCMNSCGHHHIGNIGILGVDKDGA
EWYQVSLGGEQGTAAGGARLGRVIGPSFSAEEVPDVISKLIDTFVESRIDGERFIDTYERIGIAPFKERVYAARQTAHA
>Mature_559_residues
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEDEFRPLRLQNGLYMQRHAYMHRIAIPYGNLRSVQLRMLARIAREHDR
GYGHFSTRSNIQYNWVKLEETPEILAKLASVQMHAIQTSGNCIRNITADQFAGVAQDEELDPRPWAEILRQWSTFHPEFA
WLPRKFKIAVSGSKADRAAVQIHDLGVYLKKNDAGEVVASILAGGGLGRTPIVGAIIRENLPWQHLLTYCEAVLRVYNRY
GRRDNLYKARIKILVKALSPAKFAQQVEAEWQHLKDGPSTLTQAELERVSQFFQPPAYEKLADTDASFEQHLLENRAFAR
WVERNVAPHKVPGYAAVTLSLKNHRVAPGDASAEQMEQVADWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAG
FATPNVGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGDVSLNISGCMNSCGHHHIGNIGILGVDKDGA
EWYQVSLGGEQGTAAGGARLGRVIGPSFSAEEVPDVISKLIDTFVESRIDGERFIDTYERIGIAPFKERVYAARQTAHA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 62793; Mature: 62793

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEDEFRPLRLQNGLYMQRHAYMHRIAIPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCC
GNLRSVQLRMLARIAREHDRGYGHFSTRSNIQYNWVKLEETPEILAKLASVQMHAIQTSG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHEECCC
NCIRNITADQFAGVAQDEELDPRPWAEILRQWSTFHPEFAWLPRKFKIAVSGSKADRAAV
CHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCCCEEEEEECCCCCCHHEE
QIHDLGVYLKKNDAGEVVASILAGGGLGRTPIVGAIIRENLPWQHLLTYCEAVLRVYNRY
EEEEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GRRDNLYKARIKILVKALSPAKFAQQVEAEWQHLKDGPSTLTQAELERVSQFFQPPAYEK
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHH
LADTDASFEQHLLENRAFARWVERNVAPHKVPGYAAVTLSLKNHRVAPGDASAEQMEQVA
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
DWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAGFATPNVGLLTDIIACPGGDF
HHHHHCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
CSLANAKSIPIALAIQQRFDDLDYVYDLGDVSLNISGCMNSCGHHHIGNIGILGVDKDGA
CCCCCCCCCCEEEEEHHHCCCHHHHEECCCCEEEHHHHHHCCCCCCCCCEEEEEECCCCC
EWYQVSLGGEQGTAAGGARLGRVIGPSFSAEEVPDVISKLIDTFVESRIDGERFIDTYER
CEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IGIAPFKERVYAARQTAHA
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEDEFRPLRLQNGLYMQRHAYMHRIAIPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCC
GNLRSVQLRMLARIAREHDRGYGHFSTRSNIQYNWVKLEETPEILAKLASVQMHAIQTSG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHEECCC
NCIRNITADQFAGVAQDEELDPRPWAEILRQWSTFHPEFAWLPRKFKIAVSGSKADRAAV
CHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCCCEEEEEECCCCCCHHEE
QIHDLGVYLKKNDAGEVVASILAGGGLGRTPIVGAIIRENLPWQHLLTYCEAVLRVYNRY
EEEEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GRRDNLYKARIKILVKALSPAKFAQQVEAEWQHLKDGPSTLTQAELERVSQFFQPPAYEK
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHH
LADTDASFEQHLLENRAFARWVERNVAPHKVPGYAAVTLSLKNHRVAPGDASAEQMEQVA
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
DWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAGFATPNVGLLTDIIACPGGDF
HHHHHCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
CSLANAKSIPIALAIQQRFDDLDYVYDLGDVSLNISGCMNSCGHHHIGNIGILGVDKDGA
CCCCCCCCCCEEEEEHHHCCCHHHHEECCCCEEEHHHHHHCCCCCCCCCEEEEEECCCCC
EWYQVSLGGEQGTAAGGARLGRVIGPSFSAEEVPDVISKLIDTFVESRIDGERFIDTYER
CEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IGIAPFKERVYAARQTAHA
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]