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The map label for this gene is murB [H]

Identifier: 126454230

GI number: 126454230

Start: 903706

End: 904749

Strand: Direct

Name: murB [H]

Synonym: BURPS1106A_0920

Alternate gene names: 126454230

Gene position: 903706-904749 (Clockwise)

Preceding gene: 126454626

Following gene: 126452039

Centisome position: 22.66

GC content: 71.65

Gene sequence:

>1044_bases
ATGTCCCGTCCCGATTCCGCCGTTTCGTTGCTTCCCGACTATTCGCTGCGCGCGCACAACACGTTCGGCTTCGATGCGCG
CGCGCGCGTCGCCGCGCGCATCGGCTCTCCCGGGCAGTTCGCGTCGCTCGCGCGCGATCCGCGCGTCGCGGGGCTCGACA
GGCTCGTGCTCGGCGGCGGCAGCAACGTGGTGTTCACGCGCGACTTCGACGGCCTCGTGCTGCTCGACGAGATCCGCGGC
CGCGCGCTCGTGCGCGAGGACGACGGCGCGTGGTATGTCGAGGCGGGCGGCGGCGAGAACTGGCATGCGTTCGTCGAATG
GACGCTCGCCGAAGGAATGCCCGGGCTCGAGAATCTCGCGCTCATTCCGGGCACGGTCGGCGCGGCGCCGATCCAGAACA
TCGGCGCGTACGGGCTCGAGATGAAGGAGCACTTCGCGTCGCTGCGCGCGGTCGACCTTGCGACGGGCGAGCTGGTCGAA
TTCGATGCGGCGCGCTGCGCGTTCGGCTATCGGGACAGCTTCTTCAAGCGGGACGGGCGCGGCCGTTTCGCGATCGTGGC
GGTGACGTTCCGGCTGCCGAAAGCCTGGACGCCGCGCATCGGCTATGCGGACGTCGCGCGCGAACTCGCCGCGCGCGGCA
TCGACGCGCGCGCCGCGCGTGCGCGAGACGTGTTCGACGCGGTCGTCGCGATCCGGCGCGCGAAGCTGCCCGATCCGCTC
GCGCTCGGCAACGCGGGCAGTTTCTTCAAGAACCCGGTGATCGACGCGCAAGCGTTCGCCGCGTTGCGCGCGCGCGAGCC
CGATATCGTGTCGTATCCGCAGCCGGACGGCCGCGTGAAGCTCGCGGCCGGCTGGCTGATCGACCGCTGCGGGTGGAAGG
GGCGCGCGCTCGGCGCGGCGGCCGTCCACGAGCGGCAGGCGCTCGTGCTCGTCAATCTCGGCGGCGCGTCGGGCGCCGAC
GTGCTCGCGCTCGCGCATGCGATCCGGCGCGATGTGCTCGGGCGCTTCGGCGTCGAGCTGGAAATGGAGCCGGTGTGCCT
GTAG

Upstream 100 bases:

>100_bases
GCACTCGCTATAATTGCGGACTGACCGCCATTTTACCGGCGCCCCTACATTTGCCCAAGGCCGCGAGCTTGATCGCGCGC
CGGCGCAACCGCGAATGCCG

Downstream 100 bases:

>100_bases
GCCGTGAGGCGCAGGCCACGCGCGCATCGGCCGCGTCGGCGTTCCATCGATAAAGAACCTCGCTGCCGAGCCGCTAGGTT
CTGGGTCGCGCCGCAGGCGA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSRPDSAVSLLPDYSLRAHNTFGFDARARVAARIGSPGQFASLARDPRVAGLDRLVLGGGSNVVFTRDFDGLVLLDEIRG
RALVREDDGAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAPIQNIGAYGLEMKEHFASLRAVDLATGELVE
FDAARCAFGYRDSFFKRDGRGRFAIVAVTFRLPKAWTPRIGYADVARELAARGIDARAARARDVFDAVVAIRRAKLPDPL
ALGNAGSFFKNPVIDAQAFAALRAREPDIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHERQALVLVNLGGASGAD
VLALAHAIRRDVLGRFGVELEMEPVCL

Sequences:

>Translated_347_residues
MSRPDSAVSLLPDYSLRAHNTFGFDARARVAARIGSPGQFASLARDPRVAGLDRLVLGGGSNVVFTRDFDGLVLLDEIRG
RALVREDDGAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAPIQNIGAYGLEMKEHFASLRAVDLATGELVE
FDAARCAFGYRDSFFKRDGRGRFAIVAVTFRLPKAWTPRIGYADVARELAARGIDARAARARDVFDAVVAIRRAKLPDPL
ALGNAGSFFKNPVIDAQAFAALRAREPDIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHERQALVLVNLGGASGAD
VLALAHAIRRDVLGRFGVELEMEPVCL
>Mature_346_residues
SRPDSAVSLLPDYSLRAHNTFGFDARARVAARIGSPGQFASLARDPRVAGLDRLVLGGGSNVVFTRDFDGLVLLDEIRGR
ALVREDDGAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAPIQNIGAYGLEMKEHFASLRAVDLATGELVEF
DAARCAFGYRDSFFKRDGRGRFAIVAVTFRLPKAWTPRIGYADVARELAARGIDARAARARDVFDAVVAIRRAKLPDPLA
LGNAGSFFKNPVIDAQAFAALRAREPDIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHERQALVLVNLGGASGADV
LALAHAIRRDVLGRFGVELEMEPVCL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=331, Percent_Identity=49.5468277945619, Blast_Score=320, Evalue=9e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37318; Mature: 37187

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPDSAVSLLPDYSLRAHNTFGFDARARVAARIGSPGQFASLARDPRVAGLDRLVLGGG
CCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEECC
SNVVFTRDFDGLVLLDEIRGRALVREDDGAWYVEAGGGENWHAFVEWTLAEGMPGLENLA
CEEEEEECCCCEEEEECCCCCEEEEECCCCEEEECCCCCCEEEEEEEEECCCCCCCCCEE
LIPGTVGAAPIQNIGAYGLEMKEHFASLRAVDLATGELVEFDAARCAFGYRDSFFKRDGR
ECCCCCCCCCHHHCCCCCCHHHHHHHHHEEEEECCCCEEEECHHHHHCCCCHHHHHCCCC
GRFAIVAVTFRLPKAWTPRIGYADVARELAARGIDARAARARDVFDAVVAIRRAKLPDPL
CCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
ALGNAGSFFKNPVIDAQAFAALRAREPDIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAA
EECCCCCHHCCCCCCHHHHHHHHCCCCCEECCCCCCCCEEEEECEEECCCCCCCCCCCHH
AVHERQALVLVNLGGASGADVLALAHAIRRDVLGRFGVELEMEPVCL
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure 
SRPDSAVSLLPDYSLRAHNTFGFDARARVAARIGSPGQFASLARDPRVAGLDRLVLGGG
CCCCCCEEECCCCCEEECCCCCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEECC
SNVVFTRDFDGLVLLDEIRGRALVREDDGAWYVEAGGGENWHAFVEWTLAEGMPGLENLA
CEEEEEECCCCEEEEECCCCCEEEEECCCCEEEECCCCCCEEEEEEEEECCCCCCCCCEE
LIPGTVGAAPIQNIGAYGLEMKEHFASLRAVDLATGELVEFDAARCAFGYRDSFFKRDGR
ECCCCCCCCCHHHCCCCCCHHHHHHHHHEEEEECCCCEEEECHHHHHCCCCHHHHHCCCC
GRFAIVAVTFRLPKAWTPRIGYADVARELAARGIDARAARARDVFDAVVAIRRAKLPDPL
CCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
ALGNAGSFFKNPVIDAQAFAALRAREPDIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAA
EECCCCCHHCCCCCCHHHHHHHHCCCCCEECCCCCCCCEEEEECEEECCCCCCCCCCCHH
AVHERQALVLVNLGGASGADVLALAHAIRRDVLGRFGVELEMEPVCL
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA