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The map label for this gene is dppA [H]

Identifier: 126454101

GI number: 126454101

Start: 238285

End: 239913

Strand: Direct

Name: dppA [H]

Synonym: BURPS1106A_0256

Alternate gene names: 126454101

Gene position: 238285-239913 (Clockwise)

Preceding gene: 126452735

Following gene: 126455063

Centisome position: 5.97

GC content: 62.8

Gene sequence:

>1629_bases
ATGGAACATAACCGTCTGTTGCGCGCACTGCGTGCTACCGCCATCGCGGGCGTTGCAGCGGCATCGTTCGGCATCGCGGG
TTCTGCATTCGCACAGATCCCGAACAAAACGCTCGTCTACTGCTCAGAAGGCAGCCCGGCGGGCTTCGATTCCGCGCAAT
TCACGACGGGCGTCGATTTCACCGCGTCGACGTTCCCGATCTACAACCGCCTCGTCGAATTCGAGCGCGGCGGCACGAAG
GTCGAGCCGGGCCTCGCCGAGAAGTGGGACATCTCGGCCGACGGCAAGGTCTACACGTTCCATCTGCGCCACGGCGTCAA
GTTCCATACGACCGATTTCTTCAAGCCCACGCGCGAATTCAACGCGGACGACGTCGCGTTCACGTTCGAGCGGATGCTCG
ATCCGAATCAGGCGTTTCGCAAGGCGTACCCGGTGTCGTTCCCGTACTTCACCGACATGGGCCTCGACAAGCTGATCGTG
AAGATCGAGAAGCTCGATCCGTACACGGTCCGCTTCACGCTGAAGGAGCCGAACGCGCCGTTCATCCAGAACCTCGCGAT
GGAATTCGCGTCGATCCTCTCGGCCGAATACGCGGACCAACTGATGAAGGCGGGCAAGGCGGCCGACATCAACCAGAAGC
CGATCGGCACGGGCCCGTTCATCTTCCGCAGCTACACGAAGGACGCGACGATCCGCTTCGACGGCAATCCTGATTATTGG
AAGAAGGGCGCGGTGAAGATCTCGAAGCTGATCTTCTCGATCACGCCCGACCCGGGCGTGCGCGTGCAGAAGATCAAGCG
CAACGAGTGCCAGGTGATGAGCTATCCGCGGCCCGCGGACATCGCGACGCTGAAGGCCGATTCGAACGTCGACATGCCGT
CGCTGCCGGGCTTCAACCTCGGCTACCTCGCGTACAACGTGCAGCACAAGCCCGTCGACAAGCTCGAAGTGCGCCAGGCG
CTCGACATGGCGATCAACAAGAAGGCGATTCTCGAATCCGTCTATCAGGGCGCGGGCCAGGCGGCGAGCGCGCCGATGCC
GCCGACCCAATGGTCGTACGACAAGAACCTGAAGGCCGCCGCCTACGATCCGGCGAAGGCGAAGGCGCTGCTCGCGAAGG
CGGGCTACCCGAACGGCTTCCCGATCACGCTGTGGGCGATGCCCGTGCAGCGCCCGTACAACCCGAACGCGAAGCTGATG
GCCGAGATGATCCAGGCCGACTGGGCGAAGATCGGCGTGCAGGCGAAGATCGTCACGTACGAGTGGGGCGAGTACATCAA
GCGCGCGCATGCGGGCGAGCACGATACGATGCTGATCGGCTGGAACGGCGACAACGGCGATCCCGACAACTGGCTCGGCA
CGCTGCTCGGCTGCGAGGCGGTCAAGGGCAACAACTTCTCCGAGTGGTGCTACAAGCCGTTCGACGAGCTGATCCAGAAG
GGCCGCGTGACGACGTCGCAGGACGGCCGCACGAAGATCTACATGCAGGCGCAGCAGATCTTCGCGCAGCAACTGCCGTT
CTCGCCGATCGCGAACTCGACCGTCTATCAGCCGGTGCGCAAGAACATCGTCGACATGCGGATCGAGCCGCTCGGCTATG
CGCGCTTCGACGGCGTCAGCGTGAAATAA

Upstream 100 bases:

>100_bases
ACGGATGGTTTTTTCTCCAGCTTGTTCCTCTTACGAAAGCTCAAGTAATATCCGCCTACGCCGGCCTAGGCCGGCCTTGA
ACCGGAGACCTGGAGGAAAC

Downstream 100 bases:

>100_bases
GCGCGTCGGTGCGCCGTTAGCCCGACTGCACGATAATCACCCGGCGACGGGGGGCCATGAGCTCCTCGTCGCCGGTCGCA
CATTTCCCACAAGAAAATAT

Product: dipeptide ABC transporter, periplasmic dipeptide-binding protein DppA

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MEHNRLLRALRATAIAGVAAASFGIAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTASTFPIYNRLVEFERGGTK
VEPGLAEKWDISADGKVYTFHLRHGVKFHTTDFFKPTREFNADDVAFTFERMLDPNQAFRKAYPVSFPYFTDMGLDKLIV
KIEKLDPYTVRFTLKEPNAPFIQNLAMEFASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSLPGFNLGYLAYNVQHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAAAYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLM
AEMIQADWAKIGVQAKIVTYEWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
GRVTTSQDGRTKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNIVDMRIEPLGYARFDGVSVK

Sequences:

>Translated_542_residues
MEHNRLLRALRATAIAGVAAASFGIAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTASTFPIYNRLVEFERGGTK
VEPGLAEKWDISADGKVYTFHLRHGVKFHTTDFFKPTREFNADDVAFTFERMLDPNQAFRKAYPVSFPYFTDMGLDKLIV
KIEKLDPYTVRFTLKEPNAPFIQNLAMEFASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSLPGFNLGYLAYNVQHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAAAYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLM
AEMIQADWAKIGVQAKIVTYEWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
GRVTTSQDGRTKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNIVDMRIEPLGYARFDGVSVK
>Mature_542_residues
MEHNRLLRALRATAIAGVAAASFGIAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTASTFPIYNRLVEFERGGTK
VEPGLAEKWDISADGKVYTFHLRHGVKFHTTDFFKPTREFNADDVAFTFERMLDPNQAFRKAYPVSFPYFTDMGLDKLIV
KIEKLDPYTVRFTLKEPNAPFIQNLAMEFASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSLPGFNLGYLAYNVQHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAAAYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLM
AEMIQADWAKIGVQAKIVTYEWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
GRVTTSQDGRTKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNIVDMRIEPLGYARFDGVSVK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=519, Percent_Identity=55.2986512524085, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1787551, Length=512, Percent_Identity=34.5703125, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI1787052, Length=459, Percent_Identity=28.5403050108932, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1787762, Length=498, Percent_Identity=26.3052208835341, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1789887, Length=543, Percent_Identity=27.8084714548803, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787495, Length=452, Percent_Identity=24.3362831858407, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1789397, Length=502, Percent_Identity=22.7091633466135, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87081878, Length=566, Percent_Identity=22.6148409893993, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60414; Mature: 60414

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHNRLLRALRATAIAGVAAASFGIAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDF
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCC
TASTFPIYNRLVEFERGGTKVEPGLAEKWDISADGKVYTFHLRHGVKFHTTDFFKPTREF
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCHHCC
NADDVAFTFERMLDPNQAFRKAYPVSFPYFTDMGLDKLIVKIEKLDPYTVRFTLKEPNAP
CCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCHHHHHHEEECCCCEEEEEEEECCCCH
FIQNLAMEFASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCHH
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSLPGFNL
HHHHHEEEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVQHKPVDKLEVRQALDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
AYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLMAEMIQADWAKIGVQAKIVTY
CCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEE
EWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
HHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHHC
GRVTTSQDGRTKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNIVDMRIEPLGYARFDGVS
CCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEECCCCCEECCCCC
VK
CC
>Mature Secondary Structure
MEHNRLLRALRATAIAGVAAASFGIAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDF
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCC
TASTFPIYNRLVEFERGGTKVEPGLAEKWDISADGKVYTFHLRHGVKFHTTDFFKPTREF
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCHHCC
NADDVAFTFERMLDPNQAFRKAYPVSFPYFTDMGLDKLIVKIEKLDPYTVRFTLKEPNAP
CCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCHHHHHHEEECCCCEEEEEEEECCCCH
FIQNLAMEFASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCHH
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSLPGFNL
HHHHHEEEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVQHKPVDKLEVRQALDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
AYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLMAEMIQADWAKIGVQAKIVTY
CCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEE
EWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
HHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHHC
GRVTTSQDGRTKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNIVDMRIEPLGYARFDGVS
CCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEECCCCCEECCCCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]