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The map label for this gene is kdgK [H]

Identifier: 126454092

GI number: 126454092

Start: 2185030

End: 2185956

Strand: Reverse

Name: kdgK [H]

Synonym: BURPS1106A_2198

Alternate gene names: 126454092

Gene position: 2185956-2185030 (Counterclockwise)

Preceding gene: 126454903

Following gene: 126452677

Centisome position: 54.81

GC content: 72.71

Gene sequence:

>927_bases
ATGCCGGCGACGTTTCCGGACGTGCTCGCGCTCGGCGAGGCGATGGTCGAATTCAACCAGGCGCGGCCGGGCGAGCCGAA
TTATCTGCAGGGCTTCGGCGGCGATACGTCGAACTTCTGCATCGCCGCCGCGCGGCAAGGCGCGCGCGCCGGTTTCGTGT
CCGCGGTCGGCGGCGATCATTTCGGGCGGCTGCTGCTCGATCTGTGGCGCGGCGAGCGCGTCGACACGTCGTATGTGCGG
GTCGACGACGGCGCGCCGACGGGCGTCTACTTCGTGTCGCACGGCGAGCACGGTCACGCGTTCGACTATCTGCGCGCGGG
CTCGGCCGCGAGCCGCTACGCGATCCGCGATCTGCCGCTCGATGCGCTCGCGGCCGCGCGCTTCGTCCATCTGTCGGGCG
TGAGCCTCGCGATCAGCACGAGCGCGTGCGATGCGGCGTTCGCCGCGATCGCGCATGCGCGCGCGAACGGCGCGCGCGTG
AGCTTCGACACGAACCTGCGGCTCAAGCTCTGGCCGCTGCCGCGCGCGCGGGCGGTGATGACGGAGGCGCTGCGCCATAC
CGATGTCTGCCTGCCGAGCTGGGATGACGTGACGGCGCTCACCGGGCTCGACGAGCGCGATGCGATCGTCGATGCGCTGC
TCGCCTTGGGGCCGCGCGTCGTCGCGCTGAAGCTCGGCCGCGAGGGCGCGTATGTCGCGACGCCCGGCGAGCGGCGCGTC
GTGCCCGGCTTCGTCGTCGACGCGCTCGACGCGACGGGCGCGGGCGACTGCTTCGGCGGTGCGTTCGTCGCGCGGCTCGC
CGCGGGCGATGATCCGTTCTCGGCCGCACGCTATGCGAACGCGGCGGCCGCGCTATCGACGCAAGGGTTCGGCGCGGTCG
CGCCGATCCCGTCGCGCGACGCGGTCGAGCGGCTATTGGGCGCGTGA

Upstream 100 bases:

>100_bases
AGCCGGCGGCCAAGGCGTCGAAGCGCTACAAGGTCGGCGAGTTCGTGTCCGTGAAGATCACGGGCGCCGACGGCCACGAT
CTGTGGGGCGAGGTCTGACG

Downstream 100 bases:

>100_bases
GCCCGCGCGCGCGGCGCGCGATCCGAATGCATGACGTGCGCGGCCGCGACCGCGCGCTCCATCGGTTTTCATCAAGAGAA
GAGAGGGAGGCAACGATGCA

Product: PfkB family kinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MPATFPDVLALGEAMVEFNQARPGEPNYLQGFGGDTSNFCIAAARQGARAGFVSAVGGDHFGRLLLDLWRGERVDTSYVR
VDDGAPTGVYFVSHGEHGHAFDYLRAGSAASRYAIRDLPLDALAAARFVHLSGVSLAISTSACDAAFAAIAHARANGARV
SFDTNLRLKLWPLPRARAVMTEALRHTDVCLPSWDDVTALTGLDERDAIVDALLALGPRVVALKLGREGAYVATPGERRV
VPGFVVDALDATGAGDCFGGAFVARLAAGDDPFSAARYANAAAALSTQGFGAVAPIPSRDAVERLLGA

Sequences:

>Translated_308_residues
MPATFPDVLALGEAMVEFNQARPGEPNYLQGFGGDTSNFCIAAARQGARAGFVSAVGGDHFGRLLLDLWRGERVDTSYVR
VDDGAPTGVYFVSHGEHGHAFDYLRAGSAASRYAIRDLPLDALAAARFVHLSGVSLAISTSACDAAFAAIAHARANGARV
SFDTNLRLKLWPLPRARAVMTEALRHTDVCLPSWDDVTALTGLDERDAIVDALLALGPRVVALKLGREGAYVATPGERRV
VPGFVVDALDATGAGDCFGGAFVARLAAGDDPFSAARYANAAAALSTQGFGAVAPIPSRDAVERLLGA
>Mature_307_residues
PATFPDVLALGEAMVEFNQARPGEPNYLQGFGGDTSNFCIAAARQGARAGFVSAVGGDHFGRLLLDLWRGERVDTSYVRV
DDGAPTGVYFVSHGEHGHAFDYLRAGSAASRYAIRDLPLDALAAARFVHLSGVSLAISTSACDAAFAAIAHARANGARVS
FDTNLRLKLWPLPRARAVMTEALRHTDVCLPSWDDVTALTGLDERDAIVDALLALGPRVVALKLGREGAYVATPGERRVV
PGFVVDALDATGAGDCFGGAFVARLAAGDDPFSAARYANAAAALSTQGFGAVAPIPSRDAVERLLGA

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=289, Percent_Identity=27.681660899654, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87082281, Length=302, Percent_Identity=29.4701986754967, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081971, Length=323, Percent_Identity=28.7925696594427, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790193, Length=255, Percent_Identity=29.0196078431373, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17532905, Length=295, Percent_Identity=27.4576271186441, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 32198; Mature: 32066

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATFPDVLALGEAMVEFNQARPGEPNYLQGFGGDTSNFCIAAARQGARAGFVSAVGGDH
CCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCEEECCCCHH
FGRLLLDLWRGERVDTSYVRVDDGAPTGVYFVSHGEHGHAFDYLRAGSAASRYAIRDLPL
HHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHCCCH
DALAAARFVHLSGVSLAISTSACDAAFAAIAHARANGARVSFDTNLRLKLWPLPRARAVM
HHHHHHHHHEECCCEEEEECHHHHHHHHHHHHHCCCCCEEEECCCEEEEEECCCHHHHHH
TEALRHTDVCLPSWDDVTALTGLDERDAIVDALLALGPRVVALKLGREGAYVATPGERRV
HHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCEE
VPGFVVDALDATGAGDCFGGAFVARLAAGDDPFSAARYANAAAALSTQGFGAVAPIPSRD
CCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHH
AVERLLGA
HHHHHHCC
>Mature Secondary Structure 
PATFPDVLALGEAMVEFNQARPGEPNYLQGFGGDTSNFCIAAARQGARAGFVSAVGGDH
CCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCEEECCCCHH
FGRLLLDLWRGERVDTSYVRVDDGAPTGVYFVSHGEHGHAFDYLRAGSAASRYAIRDLPL
HHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHCCCH
DALAAARFVHLSGVSLAISTSACDAAFAAIAHARANGARVSFDTNLRLKLWPLPRARAVM
HHHHHHHHHEECCCEEEEECHHHHHHHHHHHHHCCCCCEEEECCCEEEEEECCCHHHHHH
TEALRHTDVCLPSWDDVTALTGLDERDAIVDALLALGPRVVALKLGREGAYVATPGERRV
HHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCEE
VPGFVVDALDATGAGDCFGGAFVARLAAGDDPFSAARYANAAAALSTQGFGAVAPIPSRD
CCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHH
AVERLLGA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]