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The map label for this gene is aaeR [H]

Identifier: 126453910

GI number: 126453910

Start: 1662639

End: 1663580

Strand: Direct

Name: aaeR [H]

Synonym: BURPS1106A_1701

Alternate gene names: 126453910

Gene position: 1662639-1663580 (Clockwise)

Preceding gene: 126453706

Following gene: 126452819

Centisome position: 41.69

GC content: 68.68

Gene sequence:

>942_bases
ATGGATACGCTCCAAAACATGCGCGTGTTCGTCCGCGTGGTCGATGCGGGCAGTTTCACGGCGGCCGCGCAGCAGCTCAA
TTCGACGACCGCGTACGCATCGCGCGCGGTGTCCGATCTCGAGGCGCACTTGCGCACGCGTCTTCTGAACCGGACGACGC
GGCGCATCGCGCTCACCGAGGCGGGCGAGCGTTATCTGCAGCGCTGCGAGCAGATCCTCGCGTACGTCGAGCAGGCGGAG
GCCGAGGCGAGCGACGCGCACGCGCGCCCGTCCGGCAAGCTGAAAGTGCACTGCATGACGAGCCTCGGCCAGCACTACAC
GGTGCCTGCGGTGTCGCGCTACCGGCAGCGCTATCCGGAAGTCCAGGTCGACCTGACGCTCGCGCAGCGGCTGCCGGATC
TGCTCGACGAAGGCTTCGACGTGTCGCTCGTCGTCGGCCGGGAGCTGCCCGATTCGGGGCTCGTGTCGCAGCGGCTCGGC
GAGACGTTCAGCGTCGTCTGCGCGTCGCGCGGCTACATCGAGCAGCACGGCGCGCCGCAGCGGCCGCAGGATCTTGCCGG
CCACGTCTGCCTCGGGATGGTCGCGCCGGGCCTGTACTGGGACGAATGGAAGCTGGTGGGGCCGCAGGGCGAGCAGAGCG
TGACGCTCGCGCCGCCGCCGTTTCGCGTGAACGTCGCCGAGGCGCTCGCGGCCGGCATTCGCGAGGGCATGGGCATCGGC
GTGCTGCCGCTCTATTCGGCGATCGCCGGGTTGCGCAACGGCGATTTCGTGCGCGTGATGCCCGAATACCGGTCGCACGT
GATGAACATCTACGCGCTCTACGCGTCGCGCCAGTATCTCGACGCGAAGATCCGCACGTGGGTCGATTTCCTGCGCGACG
AGTTGCCGTCGATCCTCGAAGCCGACGAGGCGGCGCTCGAGCGCTTCACCGTGCAGACCTGA

Upstream 100 bases:

>100_bases
CCGAATAAACCGAGAATGGTGCAACGCATTCTTACGGACATTGAGATAATATTGTTGGATGTTTGTGCAACAATCCTCCC
GGATTCAATAGGGAAATAGC

Downstream 100 bases:

>100_bases
TCCGCCGCGGCGCGCGGCGGCGCGGAATTGACGCATTTTGACGCTGCCGCAACACTTTCTTACGCTCGTGCCGCGCCGGG
TTTGCTACTGTCTTCTCCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQLNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVEQAE
AEASDAHARPSGKLKVHCMTSLGQHYTVPAVSRYRQRYPEVQVDLTLAQRLPDLLDEGFDVSLVVGRELPDSGLVSQRLG
ETFSVVCASRGYIEQHGAPQRPQDLAGHVCLGMVAPGLYWDEWKLVGPQGEQSVTLAPPPFRVNVAEALAAGIREGMGIG
VLPLYSAIAGLRNGDFVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDELPSILEADEAALERFTVQT

Sequences:

>Translated_313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQLNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVEQAE
AEASDAHARPSGKLKVHCMTSLGQHYTVPAVSRYRQRYPEVQVDLTLAQRLPDLLDEGFDVSLVVGRELPDSGLVSQRLG
ETFSVVCASRGYIEQHGAPQRPQDLAGHVCLGMVAPGLYWDEWKLVGPQGEQSVTLAPPPFRVNVAEALAAGIREGMGIG
VLPLYSAIAGLRNGDFVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDELPSILEADEAALERFTVQT
>Mature_313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQLNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVEQAE
AEASDAHARPSGKLKVHCMTSLGQHYTVPAVSRYRQRYPEVQVDLTLAQRLPDLLDEGFDVSLVVGRELPDSGLVSQRLG
ETFSVVCASRGYIEQHGAPQRPQDLAGHVCLGMVAPGLYWDEWKLVGPQGEQSVTLAPPPFRVNVAEALAAGIREGMGIG
VLPLYSAIAGLRNGDFVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDELPSILEADEAALERFTVQT

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=35.3741496598639, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=32.996632996633, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=30.6620209059233, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=31.4878892733564, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=30.2013422818792, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=26.027397260274, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=24.7422680412371, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789173, Length=189, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693105, Length=120, Percent_Identity=27.5, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787879, Length=153, Percent_Identity=30.718954248366, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=25.0836120401338, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786448, Length=297, Percent_Identity=20.8754208754209, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788748, Length=120, Percent_Identity=30, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=134, Percent_Identity=26.1194029850746, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34778; Mature: 34778

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLQNMRVFVRVVDAGSFTAAAQQLNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHEEHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVEQAEAEASDAHARPSGKLKVHCMTSLGQHYTVPAVSRYRQRYPE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHCCC
VQVDLTLAQRLPDLLDEGFDVSLVVGRELPDSGLVSQRLGETFSVVCASRGYIEQHGAPQ
EEEEHHHHHHCHHHHHCCCCEEEEECCCCCCCCHHHHHHCHHHHHHHHCCCCHHHCCCCC
RPQDLAGHVCLGMVAPGLYWDEWKLVGPQGEQSVTLAPPPFRVNVAEALAAGIREGMGIG
CHHHHHHHHHHHHHCCCCEECCEEEECCCCCCEEEECCCCCEEEHHHHHHHHHHHCCCCC
VLPLYSAIAGLRNGDFVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDELPSILE
HHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADEAALERFTVQT
HHHHHHHHHCCCC
>Mature Secondary Structure
MDTLQNMRVFVRVVDAGSFTAAAQQLNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHEEHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVEQAEAEASDAHARPSGKLKVHCMTSLGQHYTVPAVSRYRQRYPE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHCCC
VQVDLTLAQRLPDLLDEGFDVSLVVGRELPDSGLVSQRLGETFSVVCASRGYIEQHGAPQ
EEEEHHHHHHCHHHHHCCCCEEEEECCCCCCCCHHHHHHCHHHHHHHHCCCCHHHCCCCC
RPQDLAGHVCLGMVAPGLYWDEWKLVGPQGEQSVTLAPPPFRVNVAEALAAGIREGMGIG
CHHHHHHHHHHHHHCCCCEECCEEEECCCCCCEEEECCCCCEEEHHHHHHHHHHHCCCCC
VLPLYSAIAGLRNGDFVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDELPSILE
HHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADEAALERFTVQT
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]