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The map label for this gene is pgsA [H]

Identifier: 126453875

GI number: 126453875

Start: 2783147

End: 2783740

Strand: Reverse

Name: pgsA [H]

Synonym: BURPS1106A_2828

Alternate gene names: 126453875

Gene position: 2783740-2783147 (Counterclockwise)

Preceding gene: 126454241

Following gene: 126452077

Centisome position: 69.79

GC content: 63.64

Gene sequence:

>594_bases
ATGCCGTTCAATTTCCCGATTTTCCTGACGTGGGTGCGAATCGTGCTGATTCCGCTCGTCGTCGGTGTGTTTTATCTGCC
GGATACGATGCTGAGCGCCGACCATCGCAATCTGGCGGCGGCCGTGATTTTCATTCTCGCCGCGCTGACCGACTGGTTCG
ACGGTTATCTCGCGCGGAAGTGGAACCAGACGTCGGCGTTCGGCGCGTTTCTCGACCCGGTCGCCGACAAGCTGATGGTG
ACGGCCGCGCTGCTGATGCTCGTGCAGCTCGCGCGCATCGACGCGGCGATCGCGCTCGTGATCGTCGGCCGCGAAATCGC
GATCTCGGCGCTGCGCGAATGGATGGCGCAGATCGGCGCATCGAAGAGCGTCGCGGTGAATTCGCTGGGCAAGTTCAAGA
CCGCGTGCCAGATGGTCGCGATTCCGATGCTGCTCTTCTACGGCCGGCTGCCGTTCGGCGGCGGCGTCGCGATCGACACG
CGCGGATGGGGCGAATGGCTGATCTATCTCGCGGCCGTGTTGACCATCTGGTCGATGCTTTACTACATGAAGCTCGCGTG
GCCGCAGATTCGCGAGCGCGGCGGCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCGGCTCGCGCCGGGCGGCGCGGCCCGTGCCGGGCGCCTTGCTTGTGGCGGCGCGGGCGACGCGGCACAATGGCAAATC
CTTCAACCGTGTCGCGTGCC

Downstream 100 bases:

>100_bases
GCGCGCCGCGGACCCGCACGGCGAGGCACGGGGCGAACACACGCTGAACTGCAGGCCGGATGGCGCGTCGGCAAGGGCAT
CGAGGTCGTCGAAGAAAAAG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MPFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALTDWFDGYLARKWNQTSAFGAFLDPVADKLMV
TAALLMLVQLARIDAAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTACQMVAIPMLLFYGRLPFGGGVAIDT
RGWGEWLIYLAAVLTIWSMLYYMKLAWPQIRERGGAA

Sequences:

>Translated_197_residues
MPFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALTDWFDGYLARKWNQTSAFGAFLDPVADKLMV
TAALLMLVQLARIDAAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTACQMVAIPMLLFYGRLPFGGGVAIDT
RGWGEWLIYLAAVLTIWSMLYYMKLAWPQIRERGGAA
>Mature_196_residues
PFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALTDWFDGYLARKWNQTSAFGAFLDPVADKLMVT
AALLMLVQLARIDAAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTACQMVAIPMLLFYGRLPFGGGVAIDTR
GWGEWLIYLAAVLTIWSMLYYMKLAWPQIRERGGAA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=189, Percent_Identity=48.1481481481481, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21786; Mature: 21655

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALTDWFDGYLARK
CCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSAFGAFLDPVADKLMVTAALLMLVQLARIDAAIALVIVGREIAISALREWMAQIGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSVAVNSLGKFKTACQMVAIPMLLFYGRLPFGGGVAIDTRGWGEWLIYLAAVLTIWSML
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
YYMKLAWPQIRERGGAA
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALTDWFDGYLARK
CCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSAFGAFLDPVADKLMVTAALLMLVQLARIDAAIALVIVGREIAISALREWMAQIGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSVAVNSLGKFKTACQMVAIPMLLFYGRLPFGGGVAIDTRGWGEWLIYLAAVLTIWSML
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
YYMKLAWPQIRERGGAA
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]