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The map label for this gene is ribD [H]

Identifier: 126453712

GI number: 126453712

Start: 2995111

End: 2996247

Strand: Direct

Name: ribD [H]

Synonym: BURPS1106A_3065

Alternate gene names: 126453712

Gene position: 2995111-2996247 (Clockwise)

Preceding gene: 126452611

Following gene: 126454751

Centisome position: 75.09

GC content: 72.21

Gene sequence:

>1137_bases
ATGTTCTCGGAAAGCGACTTCACCCACATGCAGCGCGCGCTCGCGCTCGCCGCGCGCGGGATGTACACGACGACGCCGAA
CCCGCGCGTCGGCTGCGTGATCGTCAAGGACGACGTCGTGATCGGCGAGGGCTTCACGCAGCCGGCCGGCCAGGATCACG
CGGAAGTGCAGGCGCTGAAGGACGCGCGCGCGCGCGGTAACGATCTGCGCGACGCAACCGTCTACGTGACGCTCGAGCCG
TGCAGCCACTTCGGCCGCACGCCGCCGTGCGCGCACACGCTGATCGACGCGCGCGTCGGCAAGGTCGTCGCGGCGATGGA
GGACCCGAATCCGCAGGTATCCGGGCGCGGCCTCGCGATGCTGCGCGATGCGGGCATCGACGTGCGCTGCGGCCTGCTCG
CGCACGAGGCGCACGAAATGAACATCGGCTTCGTGTCGCGGATGACGCGCGGCCGCCCGTGGGTGCGGATGAAGACGGCC
GCGTCGCTCGACGGCCGCACCGCGCTCGCGTCGGGCGAAAGCAAATGGATCACGGGCGACGCCGCGCGCGACGACGGCCA
CAAGTGGCGCGCGCGCGCCTGCGCGATCCTGACGGGCATCGGCACCGTGCGCGAGGACGATCCGCAGCTCAACGTGCGCG
GCGTCGACACCCCGCGCCAGCCGCGCCGCGTGCTGATCGACAGCCGCCTGGACATTCCGCTCGCCGCGCGCCTGCTCGAA
GGCGGCTCGCTGCTCGTTTTCTGCGGCGCGCTCGACGCGCAGAGCGAGCCGCGCGCGGACGCGCTGCGCGCGCGCGGCGC
GGAGATCGTGCCGCTCGCGAACGCGCGCGGCAAGGTCGATCTGCCCGCGATGCTCGCCGCGCTCGGCGAGCGCGGCATCA
ACGAACTGCACGTCGAGGCGGGCCACAAGCTGAACGGCTCGCTGCTGCGCGAGCGCTGCGTCGACGAGTTGCTCGTCTAT
CTCGCGCCGAGCCTGCTCGGCGCGGACGCCGCGGCGATGTTCGATCTCGCCGCGCCGGCGTCGCTCGTCGACCGCACGCG
GCTCGCGTTCCACAGCGTCGAGCGCGTCGGCGACGACCTGCGCATTCTCGCGCGCTTCGCGAACGCTCACGCGAGCGCCT
CCCCTACTCATTCATAA

Upstream 100 bases:

>100_bases
GCGCACGACGACGCGACGCTCGACGCGACGCTCGACGCCGCCCGCCGCGCGTTCGCCGCGCTGCGTGCCTGACCGGCCGC
ACGACTGACAGGACGAACCG

Downstream 100 bases:

>100_bases
CGGAATCCGACACGATGTTTACCGGAATCGTCGCGGCGGTCGGCCGCATCGAAGCGATCACGCCGATCGCCGCCTCGCCC
GATGCGGGCGTGCGCCTCAC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MFSESDFTHMQRALALAARGMYTTTPNPRVGCVIVKDDVVIGEGFTQPAGQDHAEVQALKDARARGNDLRDATVYVTLEP
CSHFGRTPPCAHTLIDARVGKVVAAMEDPNPQVSGRGLAMLRDAGIDVRCGLLAHEAHEMNIGFVSRMTRGRPWVRMKTA
ASLDGRTALASGESKWITGDAARDDGHKWRARACAILTGIGTVREDDPQLNVRGVDTPRQPRRVLIDSRLDIPLAARLLE
GGSLLVFCGALDAQSEPRADALRARGAEIVPLANARGKVDLPAMLAALGERGINELHVEAGHKLNGSLLRERCVDELLVY
LAPSLLGADAAAMFDLAAPASLVDRTRLAFHSVERVGDDLRILARFANAHASASPTHS

Sequences:

>Translated_378_residues
MFSESDFTHMQRALALAARGMYTTTPNPRVGCVIVKDDVVIGEGFTQPAGQDHAEVQALKDARARGNDLRDATVYVTLEP
CSHFGRTPPCAHTLIDARVGKVVAAMEDPNPQVSGRGLAMLRDAGIDVRCGLLAHEAHEMNIGFVSRMTRGRPWVRMKTA
ASLDGRTALASGESKWITGDAARDDGHKWRARACAILTGIGTVREDDPQLNVRGVDTPRQPRRVLIDSRLDIPLAARLLE
GGSLLVFCGALDAQSEPRADALRARGAEIVPLANARGKVDLPAMLAALGERGINELHVEAGHKLNGSLLRERCVDELLVY
LAPSLLGADAAAMFDLAAPASLVDRTRLAFHSVERVGDDLRILARFANAHASASPTHS
>Mature_378_residues
MFSESDFTHMQRALALAARGMYTTTPNPRVGCVIVKDDVVIGEGFTQPAGQDHAEVQALKDARARGNDLRDATVYVTLEP
CSHFGRTPPCAHTLIDARVGKVVAAMEDPNPQVSGRGLAMLRDAGIDVRCGLLAHEAHEMNIGFVSRMTRGRPWVRMKTA
ASLDGRTALASGESKWITGDAARDDGHKWRARACAILTGIGTVREDDPQLNVRGVDTPRQPRRVLIDSRLDIPLAARLLE
GGSLLVFCGALDAQSEPRADALRARGAEIVPLANARGKVDLPAMLAALGERGINELHVEAGHKLNGSLLRERCVDELLVY
LAPSLLGADAAAMFDLAAPASLVDRTRLAFHSVERVGDDLRILARFANAHASASPTHS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=368, Percent_Identity=46.195652173913, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI145693172, Length=176, Percent_Identity=34.6590909090909, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40599; Mature: 40599

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSESDFTHMQRALALAARGMYTTTPNPRVGCVIVKDDVVIGEGFTQPAGQDHAEVQALK
CCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCEEEECCCCCCCCCCHHHHHHHH
DARARGNDLRDATVYVTLEPCSHFGRTPPCAHTLIDARVGKVVAAMEDPNPQVSGRGLAM
HHHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCEEE
LRDAGIDVRCGLLAHEAHEMNIGFVSRMTRGRPWVRMKTAASLDGRTALASGESKWITGD
EECCCCCEEECHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCEEECC
AARDDGHKWRARACAILTGIGTVREDDPQLNVRGVDTPRQPRRVLIDSRLDIPLAARLLE
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHHHHHHC
GGSLLVFCGALDAQSEPRADALRARGAEIVPLANARGKVDLPAMLAALGERGINELHVEA
CCCEEEEEECCCCCCCCCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEECCC
GHKLNGSLLRERCVDELLVYLAPSLLGADAAAMFDLAAPASLVDRTRLAFHSVERVGDDL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHH
RILARFANAHASASPTHS
HHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFSESDFTHMQRALALAARGMYTTTPNPRVGCVIVKDDVVIGEGFTQPAGQDHAEVQALK
CCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCEEEECCCCCCCCCCHHHHHHHH
DARARGNDLRDATVYVTLEPCSHFGRTPPCAHTLIDARVGKVVAAMEDPNPQVSGRGLAM
HHHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCEEE
LRDAGIDVRCGLLAHEAHEMNIGFVSRMTRGRPWVRMKTAASLDGRTALASGESKWITGD
EECCCCCEEECHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCEEECC
AARDDGHKWRARACAILTGIGTVREDDPQLNVRGVDTPRQPRRVLIDSRLDIPLAARLLE
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHHHHHHC
GGSLLVFCGALDAQSEPRADALRARGAEIVPLANARGKVDLPAMLAALGERGINELHVEA
CCCEEEEEECCCCCCCCCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEECCC
GHKLNGSLLRERCVDELLVYLAPSLLGADAAAMFDLAAPASLVDRTRLAFHSVERVGDDL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHH
RILARFANAHASASPTHS
HHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]