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The map label for this gene is purP [H]

Identifier: 126453684

GI number: 126453684

Start: 2921542

End: 2922918

Strand: Direct

Name: purP [H]

Synonym: BURPS1106A_2977

Alternate gene names: 126453684

Gene position: 2921542-2922918 (Clockwise)

Preceding gene: 126455345

Following gene: 126453119

Centisome position: 73.25

GC content: 67.1

Gene sequence:

>1377_bases
ATGGACCTCTATCAAGGCACCGCCGCGCCCGCGAAGCGCTCGGCGCTCGAGCGCCACTTCGGCATCCGCGAGTCCGGCTC
GCGGCTGCGCACCGAGATCGTCGCCGGCGTGACGACATTCCTCACCGCGATGTACATCATCGTCGTGAATCCCGGCATCC
TGTCGCAGGCGGGCGTGCCGTTCGCAGCCGCGCTCACGGCGACCGTGATCGTCAGCTTCCTCGGCAGTTGCGCGATGGGC
CTGTACGCGCGCAATCCGGTGCTCGTCGCGCCGGGCATGGGAATGAACGCGCTCTTCACGTTCGTGATGGTCCACGGCGG
CAAGATGCCGTGGCAAACCGCGCTCGGCTGCGTGTTCTGGGCAGGCGTGCTATTCGCGACACTCGCCGCGTTCAATGCGC
GCAAGCTCGTCGTCGACGCGATTCCGGCGAACCTGCGGCATGCGGTGTCGTGCGGCATCGGCCTGTTCATCAGCCTGATC
GGGCTCGTGAACGCGAAGTTCATCGTCGGCGATCCGGTGACGATCGTTCACGCGACGTCGCTCAACCCGGTGATCGTCAC
GTTTCTCGCCGGCCTCGCGGTCACGACCGTGCTCGTCGTGCGCCGCGTGACGGGCGCGCTGATGCTCGGCATCGTCGCGA
CGACGCTGCTCGCGATCCCGATCGGCCGCGTGTGGGGCGACGGCAGCGCGTACTGGCCCGCCGCGATCGCGACGAAGACG
CTCGTCAACTGGAACGGCCTCGTTGCCGCGCCGGATTTCTCCGCGCTCGGCCAGCTCGATCTGCTCGGCTCGCTGAAGGT
CGCGTACTGGCCGTTCATCTTCGTGATGCTGTTCACCGCGTTCTTCGACGCGCTCTCGACGTTCATGGCGATCTCGGAGG
CGGGCAACCTGCGCGACCGCGACGGCAATCCGCGCAACATCCGCCAATCGATGATCGTCGACGCGTTCTCGGCCGTCGTG
TCCGCGCCGCTCGGCACGAGCCCCGCGAACGCGTACATCGAATCGGCGGCCGGCATCTCGGCGGGCGGCCGCACGGGGCT
CGTCGCGGTGGTCGCGGGCTTGTGCTTCGTGCCGTTCCTGTTCCTGTCGCCGCTGCTCTCGCTCGTGCCGGCGATCGCGA
CGGCGCCCGCGCTCGTGCTCGTCGGCGTATTCATGATGGAATCGATCACGAAGATCGAATGGCACCGCTTCGACGAGGCG
ATCCCCGCGTTTCTCGCGATGATCCTGATACCGCTCACATACTCGATCACCGAAGGCATCGCATACGGCTTTCTCGCGTT
CGTCGTGCTCAAGCTCTTCACCGGCCGCCGCGGCGACGTGAAGCCCGCGATGTGGGTGGTCGCCGCGCTGTCGCTGCTGC
TCGTCGCACAACTCTGA

Upstream 100 bases:

>100_bases
TGACGGCCGCGCAACGCGCGCGCCCCGCATGCGGCGGCGCGCGAAGCGCGCGCGTTGCGACGCGTTGCGCTCGACACGAG
ACACTGAGGAGAGCTTAACG

Downstream 100 bases:

>100_bases
TTTCAATCGATACGGATTCCCCACGATGACTCAAACCGCTTTCCGCGCCCGCCTGCTGAGGTTCGACGGCGACCCCGCGC
AATCGGACGATGCGCTCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MDLYQGTAAPAKRSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVPFAAALTATVIVSFLGSCAMG
LYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFWAGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLI
GLVNAKFIVGDPVTIVHATSLNPVIVTFLAGLAVTTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
LVNWNGLVAAPDFSALGQLDLLGSLKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLRDRDGNPRNIRQSMIVDAFSAVV
SAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFLFLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEA
IPAFLAMILIPLTYSITEGIAYGFLAFVVLKLFTGRRGDVKPAMWVVAALSLLLVAQL

Sequences:

>Translated_458_residues
MDLYQGTAAPAKRSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVPFAAALTATVIVSFLGSCAMG
LYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFWAGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLI
GLVNAKFIVGDPVTIVHATSLNPVIVTFLAGLAVTTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
LVNWNGLVAAPDFSALGQLDLLGSLKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLRDRDGNPRNIRQSMIVDAFSAVV
SAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFLFLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEA
IPAFLAMILIPLTYSITEGIAYGFLAFVVLKLFTGRRGDVKPAMWVVAALSLLLVAQL
>Mature_458_residues
MDLYQGTAAPAKRSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVPFAAALTATVIVSFLGSCAMG
LYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFWAGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLI
GLVNAKFIVGDPVTIVHATSLNPVIVTFLAGLAVTTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
LVNWNGLVAAPDFSALGQLDLLGSLKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLRDRDGNPRNIRQSMIVDAFSAVV
SAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFLFLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEA
IPAFLAMILIPLTYSITEGIAYGFLAFVVLKLFTGRRGDVKPAMWVVAALSLLLVAQL

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=453, Percent_Identity=39.514348785872, Blast_Score=314, Evalue=9e-87,
Organism=Escherichia coli, GI87082309, Length=441, Percent_Identity=38.3219954648526, Blast_Score=292, Evalue=3e-80,
Organism=Escherichia coli, GI1790499, Length=436, Percent_Identity=36.9266055045872, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI48994909, Length=443, Percent_Identity=36.568848758465, Blast_Score=238, Evalue=8e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48295; Mature: 48295

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYQGTAAPAKRSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVP
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
FAAALTATVIVSFLGSCAMGLYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFW
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLIGLVNAKFIVGDPVTIVHATS
HHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECC
LNPVIVTFLAGLAVTTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LVNWNGLVAAPDFSALGQLDLLGSLKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLRDR
HCCCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGNPRNIRQSMIVDAFSAVVSAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEAIPAFLAMILIPLTYSITEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGFLAFVVLKLFTGRRGDVKPAMWVVAALSLLLVAQL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLYQGTAAPAKRSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVP
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
FAAALTATVIVSFLGSCAMGLYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFW
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLIGLVNAKFIVGDPVTIVHATS
HHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECC
LNPVIVTFLAGLAVTTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LVNWNGLVAAPDFSALGQLDLLGSLKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLRDR
HCCCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGNPRNIRQSMIVDAFSAVVSAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEAIPAFLAMILIPLTYSITEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGFLAFVVLKLFTGRRGDVKPAMWVVAALSLLLVAQL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]