Click here to switch to the map view.

The map label for this gene is add [H]

Identifier: 126455345

GI number: 126455345

Start: 2920419

End: 2921444

Strand: Direct

Name: add [H]

Synonym: BURPS1106A_2976

Alternate gene names: 126455345

Gene position: 2920419-2921444 (Clockwise)

Preceding gene: 126453002

Following gene: 126453684

Centisome position: 73.22

GC content: 66.57

Gene sequence:

>1026_bases
ATGACCCCGACATTCAAAGACAAGATCGCCCGTGCGCCGAAGGCCGAGCTGCACATCCACATCGAAGGCTCGCTCGAGCC
CGAGCTGATCTTCGAGCTCGCGCAGCGCAACGGCGTGAAGCTCGCGTACGAATCGATCGACGCGCTGCGCGCCGCGTACG
CGTTCACCGATCTGCAGTCGTTCCTCGACATCTATTACGCCGGCGCGAGCGTGCTCCTCACCGAGCAGGATTTCTACGAC
ATGACGGCCGCATACGTCGAGCGCGCGCTCGCCGATCACGTCGTGCACGCGGAGATCTTCTTCGATCCGCAGACGCACAC
CGAGCGCGGCGTGCCGATCGAGACGGTCGTCGCCGGCATCGATCGCGCGCTCGCCGACGCGGAAAAACGCGGCTTCTCGA
GCAAGCTGATCCTCTGCTTCCTGCGCCACCTGTCCGAGGAAAGCGCGCTCGCGACGTTCGACGCGGCGCTGCCGCTCTTC
GATCGCTATGCGCGGCGCCTGATCGGCGTGGGGCTCGATTCGTCCGAGCGCGGCAATCCGCCGTCGAAGTTCGCGCGCGT
GTTCGCGAAGGCGCGAGAGCGGGGCCTGAAGCTCGTCGCGCACGCGGGCGAGGAAGGCCCGCCCGAATACGTGACGCAGG
CGCTCGACGTGCTGAAGATCGACCGCGTCGATCACGGCGTGCGCAGCGCCGAGGACGCGGCGCTCGTCGCGCGCCTTGCC
GGCGAGAAGATCGCGCTCACCGTCTGCCCGCTGTCGAACCTGAAGCTCTGCGTGTTCGACGACCTGACGAAGCACACGCT
GAAGACGCTGCTCGATCGCGGCGTCGCGGTGACGATCAATTCCGACGACCCGGCGTATTTCGGCGGCTACGTCAACGAAA
ACTACTTCGCGACCGTCGACGCGCTGCAGCTTGGCGAGGCCGACGTCTACACGGTGATCAGGAACGGCTTCGAAGCGTCG
TTCGTGAGCGCCGACGAACGCGCGGCGCTGATCGCGAAGCTCGACGCGCACTGGCACGCGGCCTGA

Upstream 100 bases:

>100_bases
TCGACGCGCGGCGCGCGAACGGGCGTCCGGCCGCGCCGCCCGGCGCGAGCGCGTGCTGAATCGCCGCCATCCAAACCCGC
ATTCGACCCAAAAAACCACA

Downstream 100 bases:

>100_bases
CGGCCGCGCAACGCGCGCGCCCCGCATGCGGCGGCGCGCGAAGCGCGCGCGTTGCGACGCGTTGCGCTCGACACGAGACA
CTGAGGAGAGCTTAACGATG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYD
MTAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGIDRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLF
DRYARRLIGVGLDSSERGNPPSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLA
GEKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGVAVTINSDDPAYFGGYVNENYFATVDALQLGEADVYTVIRNGFEAS
FVSADERAALIAKLDAHWHAA

Sequences:

>Translated_341_residues
MTPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYD
MTAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGIDRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLF
DRYARRLIGVGLDSSERGNPPSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLA
GEKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGVAVTINSDDPAYFGGYVNENYFATVDALQLGEADVYTVIRNGFEAS
FVSADERAALIAKLDAHWHAA
>Mature_340_residues
TPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYDM
TAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGIDRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLFD
RYARRLIGVGLDSSERGNPPSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLAG
EKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGVAVTINSDDPAYFGGYVNENYFATVDALQLGEADVYTVIRNGFEASF
VSADERAALIAKLDAHWHAA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=352, Percent_Identity=26.9886363636364, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1787910, Length=330, Percent_Identity=30, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32565969, Length=342, Percent_Identity=23.0994152046784, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538512, Length=342, Percent_Identity=23.0994152046784, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324188, Length=335, Percent_Identity=41.7910447761194, Blast_Score=275, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24645260, Length=329, Percent_Identity=23.4042553191489, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37500; Mature: 37369

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQS
CCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
FLDIYYAGASVLLTEQDFYDMTAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHH
DRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLFDRYARRLIGVGLDSSERGNP
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLA
HHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
GEKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGVAVTINSDDPAYFGGYVNENYFATVD
CCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEEEH
ALQLGEADVYTVIRNGFEASFVSADERAALIAKLDAHWHAA
HHHCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQS
CCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
FLDIYYAGASVLLTEQDFYDMTAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHH
DRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLFDRYARRLIGVGLDSSERGNP
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLA
HHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
GEKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGVAVTINSDDPAYFGGYVNENYFATVD
CCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEEEH
ALQLGEADVYTVIRNGFEASFVSADERAALIAKLDAHWHAA
HHHCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA