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The map label for this gene is mdcB [H]

Identifier: 126453634

GI number: 126453634

Start: 1442617

End: 1443912

Strand: Direct

Name: mdcB [H]

Synonym: BURPS1106A_1487

Alternate gene names: 126453634

Gene position: 1442617-1443912 (Clockwise)

Preceding gene: 126454504

Following gene: 126451447

Centisome position: 36.17

GC content: 75.0

Gene sequence:

>1296_bases
ATGAAGCGAAACGCATGCGCGGTGGCGAAGCCGGCCCGGCGCGACGCGATGTGCCGGGATAGGGCGCGGGCGCTTGACGA
CGGAGGCGGGGCGGATACGCTGTTGGATGCGTTGGATGCGTCAGGTGTATCGAATGCGTCGAGTTCGATGGGAGCGGGGG
ACGCATCGAACCGGCCGAACATCGCAGCGGTGTCGAGCATATGGGCTTCCCAGTATTTCCCCCCGGCCACGCGGAACGCC
TCCGACGGGGCTGACGCGCGAGATAGCCGGGGGCGCCGTCGACATCCGACGTTCGCCGCGCATCGGCTAGCCTCGCTGAC
CGCGACCGCGACCGCGACCGCGACCGCGACCGCGACCGCGACCGCGACCGCGACCGCGACCGCAGCCGCAACGCCGGCAT
CCATCCCCACGCCGACGCCAAGGTCAACATCAACAGCAACGCCCACGCCAACAGCAACGGCGATCGCGGCCAACGCGGTA
CGCTGCCTGCGCGTCGAGATCGACACGTGGCCGAAGCCCGGACTCGTGAGCCACGTCGACGCGGGCAGCCACGACGACAT
GACGGCCGACACCTTCTATCGCAGCGCGGCGGCGCTTGCGCCGTTCTTCGCCGAGCTCGCCGATGCCGGCGCGCGCGACG
CCGGCATGCCGGCGCTGCGCAAGATCGGCCTGCGCGCGGAACGCGCGATGCTGGCCGCGACGGGCGGCGTGAACACGCAT
CGCGGCGCGATTTTCGGGCTCGGGCTGCTGTGCGCGGCGGCGGGCCTGCGCGGATCGCGCGAACGGCGCGCGCAACGGGG
GCAAGCCGCGGGCGCGACGCTCGGCGATCTCGTCGCCGCGCGCTGGGGCGACGAGATCGCCGGCGGTCCGCGCGCGGCCG
ACAGTCATGGCGCGCGCGCCGCGCGCCGCTACGGCGCGGGCGGCGCGCGCGCGGAGGCGGCGGGCGGTTTCGCGCGCGTC
TACGCGGTCGGCGTGCCGGCGCTGCGCGACGGCGCGCGGCGCGCGCGGGGCGACGCCGAGGCCGCGCGCGTGCACGCGTG
TTTCGCGCTGATCGCCGCGCTCGACGACGACACGAATCTGCTGCATCGCGGCGGCCGCGACGGCGTCGACTTCGCGCAAC
GAACCGCGCGCGAATTTCTCGCGGCGGGCGGCGTGGGCGCGTGCGACTGGCGCGCGCGCGCGGCCGCCGCGCATCGCGCG
TTCGTCGCCCGCCGGCTGAGCCCGGGCGGCGCGGCGGACCTGCTCGCGATGAGCCTCTTCGTCGCCGCGCTCGACGACGC
GCGGGCATTGCCGTGA

Upstream 100 bases:

>100_bases
TGAACTGGCGCGAACTGCATGCGGGCGGGCGAGCAGTCGCGATGAAAACCGCGACGGGCGTCGAACTGGTCGCTCCGCGG
ACGTTTCTGGAGGCGTGGCG

Downstream 100 bases:

>100_bases
CGATCGCGATTCTCTGTTCGGGGCAGGGCGGCCAGCATGCCGGCATGTTCGCGCTGACGGCCGATTTGCCGGAAGCCGCG
CCGCTTTTCGCGCACGCGGC

Product: triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKRNACAVAKPARRDAMCRDRARALDDGGGADTLLDALDASGVSNASSSMGAGDASNRPNIAAVSSIWASQYFPPATRNA
SDGADARDSRGRRRHPTFAAHRLASLTATATATATATATATATATATAAATPASIPTPTPRSTSTATPTPTATAIAANAV
RCLRVEIDTWPKPGLVSHVDAGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPALRKIGLRAERAMLAATGGVNTH
RGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLVAARWGDEIAGGPRAADSHGARAARRYGAGGARAEAAGGFARV
YAVGVPALRDGARRARGDAEAARVHACFALIAALDDDTNLLHRGGRDGVDFAQRTAREFLAAGGVGACDWRARAAAAHRA
FVARRLSPGGAADLLAMSLFVAALDDARALP

Sequences:

>Translated_431_residues
MKRNACAVAKPARRDAMCRDRARALDDGGGADTLLDALDASGVSNASSSMGAGDASNRPNIAAVSSIWASQYFPPATRNA
SDGADARDSRGRRRHPTFAAHRLASLTATATATATATATATATATATAAATPASIPTPTPRSTSTATPTPTATAIAANAV
RCLRVEIDTWPKPGLVSHVDAGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPALRKIGLRAERAMLAATGGVNTH
RGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLVAARWGDEIAGGPRAADSHGARAARRYGAGGARAEAAGGFARV
YAVGVPALRDGARRARGDAEAARVHACFALIAALDDDTNLLHRGGRDGVDFAQRTAREFLAAGGVGACDWRARAAAAHRA
FVARRLSPGGAADLLAMSLFVAALDDARALP
>Mature_431_residues
MKRNACAVAKPARRDAMCRDRARALDDGGGADTLLDALDASGVSNASSSMGAGDASNRPNIAAVSSIWASQYFPPATRNA
SDGADARDSRGRRRHPTFAAHRLASLTATATATATATATATATATATAAATPASIPTPTPRSTSTATPTPTATAIAANAV
RCLRVEIDTWPKPGLVSHVDAGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPALRKIGLRAERAMLAATGGVNTH
RGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLVAARWGDEIAGGPRAADSHGARAARRYGAGGARAEAAGGFARV
YAVGVPALRDGARRARGDAEAARVHACFALIAALDDDTNLLHRGGRDGVDFAQRTAREFLAAGGVGACDWRARAAAAHRA
FVARRLSPGGAADLLAMSLFVAALDDARALP

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=301, Percent_Identity=33.5548172757475, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 43866; Mature: 43866

Theoretical pI: Translated: 10.92; Mature: 10.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNACAVAKPARRDAMCRDRARALDDGGGADTLLDALDASGVSNASSSMGAGDASNRPN
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
IAAVSSIWASQYFPPATRNASDGADARDSRGRRRHPTFAAHRLASLTATATATATATATA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TATATATAAATPASIPTPTPRSTSTATPTPTATAIAANAVRCLRVEIDTWPKPGLVSHVD
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCEEEEEEEECCCCCCCCCEECC
AGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPALRKIGLRAERAMLAATGGVNTH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCC
RGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLVAARWGDEIAGGPRAADSHGARA
CHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCHHCCCCCCCCHHHHHH
ARRYGAGGARAEAAGGFARVYAVGVPALRDGARRARGDAEAARVHACFALIAALDDDTNL
HHHHCCCCCCHHHCCCCEEHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHH
LHRGGRDGVDFAQRTAREFLAAGGVGACDWRARAAAAHRAFVARRLSPGGAADLLAMSLF
HHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VAALDDARALP
HHHHHHHCCCC
>Mature Secondary Structure
MKRNACAVAKPARRDAMCRDRARALDDGGGADTLLDALDASGVSNASSSMGAGDASNRPN
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
IAAVSSIWASQYFPPATRNASDGADARDSRGRRRHPTFAAHRLASLTATATATATATATA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TATATATAAATPASIPTPTPRSTSTATPTPTATAIAANAVRCLRVEIDTWPKPGLVSHVD
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCEEEEEEEECCCCCCCCCEECC
AGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPALRKIGLRAERAMLAATGGVNTH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCC
RGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLVAARWGDEIAGGPRAADSHGARA
CHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCHHCCCCCCCCHHHHHH
ARRYGAGGARAEAAGGFARVYAVGVPALRDGARRARGDAEAARVHACFALIAALDDDTNL
HHHHCCCCCCHHHCCCCEEHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHH
LHRGGRDGVDFAQRTAREFLAAGGVGACDWRARAAAAHRAFVARRLSPGGAADLLAMSLF
HHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VAALDDARALP
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10561613 [H]