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The map label for this gene is fabD [H]

Identifier: 126451447

GI number: 126451447

Start: 1443909

End: 1444847

Strand: Direct

Name: fabD [H]

Synonym: BURPS1106A_1488

Alternate gene names: 126451447

Gene position: 1443909-1444847 (Clockwise)

Preceding gene: 126453634

Following gene: 126452808

Centisome position: 36.2

GC content: 77.21

Gene sequence:

>939_bases
GTGACGATCGCGATTCTCTGTTCGGGGCAGGGCGGCCAGCATGCCGGCATGTTCGCGCTGACGGCCGATTTGCCGGAAGC
CGCGCCGCTTTTCGCGCACGCGGCGGCGTTGCTCGGCGCCGATCCGCGCGAGTGGGTGCGCGACGCCGATGACGAAGCGC
TGCGCGAGAACTTCGCCGCGCAGCTCGTGTGCACGCTGCAGGCGGTGGCCGCGATGACGCGGCTCGACGCGCTGCTGCCG
CGCAGGCGCTGCGTCGCGGGCTACAGTGTCGGCGAACTCGCCGCGTGGAGCGTCGCGGGGCTCGTGGAGGCGCGCGATGC
GCTCGATCTCGTCGCGGCCCGCGCGCGCGCGATGGACGCGGCGAGCGACGGCGATGCGCGAATGCTGTTCGTGCGCGGGC
TCGCGCGCGACGCCGTCGACGCATCGTGCGCCGCGCACGGCGCCGCGGTCGCGATCGTCAACCCGGGCGACGCATACGTG
CTCGCCGGCCCGCGCGCGGCGCTCGACGCGCTCGCCGCCGATGCGCGCGCGCGCGGGGCGGCGCGCGTCACGCCTGTCTG
CGTGCGCGTCGCGTCGCATACGCGCTGGCTCGACGCCGCCGTGCCCCGGTTTCGCGCCGCGCTCGCCGGCGCGCGCATCG
CCCGCGCGCCGGCGCCCGGCACGCGGCTCCTGTCCGGCATCGACGGCGCGCCGGTGCTCGACGTGGCGGCGGGCGCGGAC
AAGCTCGCGCGGCAGATCGCCGAGCCGCTCGACTGGGCCGCATGCGTCGCGGGCTGCGTCGAGGCGGGCGCGCGCGCGTT
CGTCGAGCTCGGGCCGGGGCGCGCGCTCGCGGAGATGGCGGCCGCCGCGTTTCCCGCGCTGCCGGCGCGCAGTCTGGCCG
ATTTCCGCTCGTGGGACGGCGTGCGCGCGTGGCTTTCCCGCGTCGATCTCGACGCCTAG

Upstream 100 bases:

>100_bases
ATCGCGCGTTCGTCGCCCGCCGGCTGAGCCCGGGCGGCGCGGCGGACCTGCTCGCGATGAGCCTCTTCGTCGCCGCGCTC
GACGACGCGCGGGCATTGCC

Downstream 100 bases:

>100_bases
CGCGCTTCGCGTGCGCGCGCGGCGACGCGCCGCGTGCCGCTCGTCGACGAAACGGTTTGCAATGAAAGAGGAGGTGGCTA
CAATTGCCGCCCCATGACAT

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTIAILCSGQGGQHAGMFALTADLPEAAPLFAHAAALLGADPREWVRDADDEALRENFAAQLVCTLQAVAAMTRLDALLP
RRRCVAGYSVGELAAWSVAGLVEARDALDLVAARARAMDAASDGDARMLFVRGLARDAVDASCAAHGAAVAIVNPGDAYV
LAGPRAALDALAADARARGAARVTPVCVRVASHTRWLDAAVPRFRAALAGARIARAPAPGTRLLSGIDGAPVLDVAAGAD
KLARQIAEPLDWAACVAGCVEAGARAFVELGPGRALAEMAAAAFPALPARSLADFRSWDGVRAWLSRVDLDA

Sequences:

>Translated_312_residues
MTIAILCSGQGGQHAGMFALTADLPEAAPLFAHAAALLGADPREWVRDADDEALRENFAAQLVCTLQAVAAMTRLDALLP
RRRCVAGYSVGELAAWSVAGLVEARDALDLVAARARAMDAASDGDARMLFVRGLARDAVDASCAAHGAAVAIVNPGDAYV
LAGPRAALDALAADARARGAARVTPVCVRVASHTRWLDAAVPRFRAALAGARIARAPAPGTRLLSGIDGAPVLDVAAGAD
KLARQIAEPLDWAACVAGCVEAGARAFVELGPGRALAEMAAAAFPALPARSLADFRSWDGVRAWLSRVDLDA
>Mature_311_residues
TIAILCSGQGGQHAGMFALTADLPEAAPLFAHAAALLGADPREWVRDADDEALRENFAAQLVCTLQAVAAMTRLDALLPR
RRCVAGYSVGELAAWSVAGLVEARDALDLVAARARAMDAASDGDARMLFVRGLARDAVDASCAAHGAAVAIVNPGDAYVL
AGPRAALDALAADARARGAARVTPVCVRVASHTRWLDAAVPRFRAALAGARIARAPAPGTRLLSGIDGAPVLDVAAGADK
LARQIAEPLDWAACVAGCVEAGARAFVELGPGRALAEMAAAAFPALPARSLADFRSWDGVRAWLSRVDLDA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=330, Percent_Identity=28.4848484848485, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1787334, Length=301, Percent_Identity=29.5681063122924, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71984332, Length=297, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24665753, Length=300, Percent_Identity=28, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32084; Mature: 31953

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAILCSGQGGQHAGMFALTADLPEAAPLFAHAAALLGADPREWVRDADDEALRENFAA
CEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHH
QLVCTLQAVAAMTRLDALLPRRRCVAGYSVGELAAWSVAGLVEARDALDLVAARARAMDA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASDGDARMLFVRGLARDAVDASCAAHGAAVAIVNPGDAYVLAGPRAALDALAADARARGA
CCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHCCC
ARVTPVCVRVASHTRWLDAAVPRFRAALAGARIARAPAPGTRLLSGIDGAPVLDVAAGAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHCCHH
KLARQIAEPLDWAACVAGCVEAGARAFVELGPGRALAEMAAAAFPALPARSLADFRSWDG
HHHHHHHHHHHHHHHHHHHHHHHHHHEEHCCCCHHHHHHHHHHCCCCCHHHHHHHHCCHH
VRAWLSRVDLDA
HHHHHHHHCCCC
>Mature Secondary Structure 
TIAILCSGQGGQHAGMFALTADLPEAAPLFAHAAALLGADPREWVRDADDEALRENFAA
EEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHH
QLVCTLQAVAAMTRLDALLPRRRCVAGYSVGELAAWSVAGLVEARDALDLVAARARAMDA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASDGDARMLFVRGLARDAVDASCAAHGAAVAIVNPGDAYVLAGPRAALDALAADARARGA
CCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHCCC
ARVTPVCVRVASHTRWLDAAVPRFRAALAGARIARAPAPGTRLLSGIDGAPVLDVAAGAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHCCHH
KLARQIAEPLDWAACVAGCVEAGARAFVELGPGRALAEMAAAAFPALPARSLADFRSWDG
HHHHHHHHHHHHHHHHHHHHHHHHHHEEHCCCCHHHHHHHHHHCCCCCHHHHHHHHCCHH
VRAWLSRVDLDA
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]