The gene/protein map for NC_009076 is currently unavailable.
Definition Burkholderia pseudomallei 1106a chromosome I, complete genome.
Accession NC_009076
Length 3,988,455

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The map label for this gene is paaF [C]

Identifier: 126453598

GI number: 126453598

Start: 674947

End: 675789

Strand: Direct

Name: paaF [C]

Synonym: BURPS1106A_0698

Alternate gene names: 126453598

Gene position: 674947-675789 (Clockwise)

Preceding gene: 126454517

Following gene: 126451820

Centisome position: 16.92

GC content: 67.5

Gene sequence:

>843_bases
ATGACGACGGTGCGCGGGCGACGAGCTCGCGCACCGTTTTTTGTTGATCGAATGAAACCAGCCACGGAGACGGCTCAAAT
GGATATCCAGATCGAAAACGCAGGCGGCGTGCTGACGATCACGCTCGCGCGCCCGGCGAAGAAGAACGCGATCACGGCGG
CGATGTACCAGACGATGGCCGATGCGCTCGCGGCGGCGCAGGACGACAAATCGGTGCGCGCGATCCTGATTCGCGGCAGC
GATGGCAACTTCAGCGCGGGCAACGATCTCGACGATTTCATGAAGGCGCCGCCGAAGGACGAGCACGCGCCCGTGTTCCA
GTTCCTGCGCCAGATCGCCGGCGCGCACAAGCCGATCGTCGCGGCGGTCGCGGGCGTCGCCGTCGGCATCGGCGTGACGA
TGCTGCTGCACTGCGATCTCGTCTACGCGGCCGACACCGCGCAGCTGTCGCTGCCGTTCGCGCAGCTCGGCCTGTGCCCG
GAGGCGGCATCGAGCCTGTTGCTGCCGCGCGTCGCCGGTCATCAGGTGGCCGCGGAGAAACTGCTGCTCGGCGAGCCGTT
CGACGCGCTCGAGGCGCACCGCATCGGCCTCGTGAACCGCGTGCTGCCCGCCGCGGATCTCGACGCGTTCGCCGCGCAGC
AGGCGGCCAAGCTCGTCGCGCTGCCGGCTTCGTCGCTGCGCGCGACGAAGGCGTTCCTCAAGAAGGGCAGCGCCGCGGAC
ATCGCCGCGCGGATGTCGGAAGAGGGGGATCAGTTCGGCAAGATGCTGCGCTCGCCCGAGGTGCGTGAGGCGATCACCGC
GTTTTTCGAGAAGCGCAAGCCGGATTTCTGGCAATTCGACTGA

Upstream 100 bases:

>100_bases
CGCCGCCGCAACCTGAAGTACGGGATGGTGACGATGTGCGTCGGCACCGGCATGGGCGCGGCGGGCATCATCGAGCGCCT
CTGATCGGAGCGCGCGACGG

Downstream 100 bases:

>100_bases
GCGCCGCGGCGGCGCGATGCGGTGCGGCGGCTTGCGGGCCGCCGCGCGCGCATGAAGCCCGACGCGTCGGCTCGCCGCCC
GCCGTGCCGCTTGCGCGTGG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTTVRGRRARAPFFVDRMKPATETAQMDIQIENAGGVLTITLARPAKKNAITAAMYQTMADALAAAQDDKSVRAILIRGS
DGNFSAGNDLDDFMKAPPKDEHAPVFQFLRQIAGAHKPIVAAVAGVAVGIGVTMLLHCDLVYAADTAQLSLPFAQLGLCP
EAASSLLLPRVAGHQVAAEKLLLGEPFDALEAHRIGLVNRVLPAADLDAFAAQQAAKLVALPASSLRATKAFLKKGSAAD
IAARMSEEGDQFGKMLRSPEVREAITAFFEKRKPDFWQFD

Sequences:

>Translated_280_residues
MTTVRGRRARAPFFVDRMKPATETAQMDIQIENAGGVLTITLARPAKKNAITAAMYQTMADALAAAQDDKSVRAILIRGS
DGNFSAGNDLDDFMKAPPKDEHAPVFQFLRQIAGAHKPIVAAVAGVAVGIGVTMLLHCDLVYAADTAQLSLPFAQLGLCP
EAASSLLLPRVAGHQVAAEKLLLGEPFDALEAHRIGLVNRVLPAADLDAFAAQQAAKLVALPASSLRATKAFLKKGSAAD
IAARMSEEGDQFGKMLRSPEVREAITAFFEKRKPDFWQFD
>Mature_279_residues
TTVRGRRARAPFFVDRMKPATETAQMDIQIENAGGVLTITLARPAKKNAITAAMYQTMADALAAAQDDKSVRAILIRGSD
GNFSAGNDLDDFMKAPPKDEHAPVFQFLRQIAGAHKPIVAAVAGVAVGIGVTMLLHCDLVYAADTAQLSLPFAQLGLCPE
AASSLLLPRVAGHQVAAEKLLLGEPFDALEAHRIGLVNRVLPAADLDAFAAQQAAKLVALPASSLRATKAFLKKGSAADI
AARMSEEGDQFGKMLRSPEVREAITAFFEKRKPDFWQFD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=267, Percent_Identity=32.9588014981273, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI260275230, Length=267, Percent_Identity=32.9588014981273, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI260274832, Length=267, Percent_Identity=32.9588014981273, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI194097323, Length=285, Percent_Identity=29.4736842105263, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI31542718, Length=280, Percent_Identity=28.9285714285714, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4757968, Length=257, Percent_Identity=26.4591439688716, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI49355787, Length=257, Percent_Identity=26.4591439688716, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI25453481, Length=271, Percent_Identity=25.4612546125461, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI51538573, Length=271, Percent_Identity=25.4612546125461, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4757966, Length=252, Percent_Identity=26.1904761904762, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI51538581, Length=252, Percent_Identity=26.1904761904762, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI68989263, Length=262, Percent_Identity=29.0076335877863, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI70995211, Length=182, Percent_Identity=31.3186813186813, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI150378541, Length=247, Percent_Identity=29.1497975708502, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4502327, Length=272, Percent_Identity=27.9411764705882, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI221136756, Length=257, Percent_Identity=22.9571984435798, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI221136753, Length=257, Percent_Identity=22.9571984435798, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI221307494, Length=257, Percent_Identity=22.9571984435798, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI116235487, Length=215, Percent_Identity=26.9767441860465, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI37594469, Length=164, Percent_Identity=29.8780487804878, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI37594471, Length=164, Percent_Identity=29.8780487804878, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI62530384, Length=234, Percent_Identity=23.9316239316239, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI157694516, Length=263, Percent_Identity=21.6730038022814, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI213417737, Length=263, Percent_Identity=21.6730038022814, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787659, Length=243, Percent_Identity=32.9218106995885, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787660, Length=248, Percent_Identity=33.8709677419355, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788597, Length=260, Percent_Identity=31.9230769230769, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI221142681, Length=257, Percent_Identity=33.4630350194552, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082183, Length=256, Percent_Identity=26.5625, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790281, Length=232, Percent_Identity=25.4310344827586, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788682, Length=204, Percent_Identity=25.9803921568627, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17535521, Length=253, Percent_Identity=33.596837944664, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17549921, Length=214, Percent_Identity=36.4485981308411, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17554946, Length=280, Percent_Identity=31.0714285714286, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=30.241935483871, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540306, Length=241, Percent_Identity=28.2157676348548, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=204, Percent_Identity=29.9019607843137, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=25.3333333333333, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=210, Percent_Identity=24.7619047619048, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=189, Percent_Identity=30.1587301587302, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=200, Percent_Identity=26, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=211, Percent_Identity=30.3317535545024, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=211, Percent_Identity=30.3317535545024, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=211, Percent_Identity=30.3317535545024, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=189, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654903, Length=256, Percent_Identity=31.25, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI20129971, Length=277, Percent_Identity=29.9638989169675, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24653477, Length=277, Percent_Identity=29.9638989169675, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24653139, Length=253, Percent_Identity=31.6205533596838, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19922422, Length=253, Percent_Identity=25.296442687747, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21357171, Length=220, Percent_Identity=28.1818181818182, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920382, Length=200, Percent_Identity=28, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24650670, Length=206, Percent_Identity=26.6990291262136, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29938; Mature: 29807

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTTVRGRRARAPFFVDRMKPATETAQMDIQIENAGGVLTITLARPAKKNAITAAMYQTMA
CCCCCCCCCCCCCHHHCCCCCCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHH
DALAAAQDDKSVRAILIRGSDGNFSAGNDLDDFMKAPPKDEHAPVFQFLRQIAGAHKPIV
HHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHH
AAVAGVAVGIGVTMLLHCDLVYAADTAQLSLPFAQLGLCPEAASSLLLPRVAGHQVAAEK
HHHHHHHHHHHHHHHHHHHHHEECCCCCEECCHHHHCCCHHHHHHHHHHHHHCHHHHHHH
LLLGEPFDALEAHRIGLVNRVLPAADLDAFAAQQAAKLVALPASSLRATKAFLKKGSAAD
HHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
IAARMSEEGDQFGKMLRSPEVREAITAFFEKRKPDFWQFD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTVRGRRARAPFFVDRMKPATETAQMDIQIENAGGVLTITLARPAKKNAITAAMYQTMA
CCCCCCCCCCCCHHHCCCCCCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHH
DALAAAQDDKSVRAILIRGSDGNFSAGNDLDDFMKAPPKDEHAPVFQFLRQIAGAHKPIV
HHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHH
AAVAGVAVGIGVTMLLHCDLVYAADTAQLSLPFAQLGLCPEAASSLLLPRVAGHQVAAEK
HHHHHHHHHHHHHHHHHHHHHEECCCCCEECCHHHHCCCHHHHHHHHHHHHHCHHHHHHH
LLLGEPFDALEAHRIGLVNRVLPAADLDAFAAQQAAKLVALPASSLRATKAFLKKGSAAD
HHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
IAARMSEEGDQFGKMLRSPEVREAITAFFEKRKPDFWQFD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA