Click here to switch to the map view.

The map label for this gene is iscR [H]

Identifier: 126453431

GI number: 126453431

Start: 2615046

End: 2615585

Strand: Reverse

Name: iscR [H]

Synonym: BURPS1106A_2656

Alternate gene names: 126453431

Gene position: 2615585-2615046 (Counterclockwise)

Preceding gene: 126454074

Following gene: 126452227

Centisome position: 65.58

GC content: 65.56

Gene sequence:

>540_bases
ATGAGACTCACCACCAAAGGCCGTTTCGCCGTCACGGCGATGATCGACTTGGCGCTACGCCAGGAGCAAGGCCCGGTGAC
GCTTGCAGGCATCAGCCAGCGCCAGCGGATTTCGCTCTCCTACCTCGAGCAATTGTTCGGCAAGTTGCGCCGGCATGAAA
TCGTCGAATCGGTCCGCGGACCGGGCGGCGGCTACAACCTCGCGCGCCGCGCGCAGGACGTGACGGTCGCCGACATCATC
ATCGCGGTCGACGAGCCGCTCGATGCGACCCAGTGCGGCGGCAAGGGCGCGTGCGAAGGCTCGAAGCAGCCCGATGGCCA
TTGCATGACGCACGAACTGTGGTCGACGCTGAACCAGAAGATGGTCGAATACCTCGATTCGGTGTCGCTGCAGGATCTCG
TCGATCAGCAGCGCGCCCGCGAGGGCACGCCGGCCGTGCTGCGCGACAAGCGCAAGCCGGAGCCCGTCGCGGCGAGCGTC
GAGCCCGTCCGCTCGGTTCCGCTCGGCCCGAATTCGGTCTTCAACATCGCGAATTCATGA

Upstream 100 bases:

>100_bases
GCGCCGCATACAACCCCTTTTAGCGGCAGGGATACTTGACTAAATTGGTCAAATATTTATACTTGACCAAAATCGTCAAG
ATTGCTGCCCATTCAATACC

Downstream 100 bases:

>100_bases
TGGCCGCGCACTGAACGCGGCCCGTACAACGAATAGTCCCCGCACTGAATGCATACCCGGAGCGATAGATGAACAACGAT
ATCCCCCACCTGCCCATCTA

Product: iron-sulfur cluster assembly transcription factor IscR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAQDVTVADII
IAVDEPLDATQCGGKGACEGSKQPDGHCMTHELWSTLNQKMVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASV
EPVRSVPLGPNSVFNIANS

Sequences:

>Translated_179_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAQDVTVADII
IAVDEPLDATQCGGKGACEGSKQPDGHCMTHELWSTLNQKMVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASV
EPVRSVPLGPNSVFNIANS
>Mature_179_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAQDVTVADII
IAVDEPLDATQCGGKGACEGSKQPDGHCMTHELWSTLNQKMVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASV
EPVRSVPLGPNSVFNIANS

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=137, Percent_Identity=51.8248175182482, Blast_Score=140, Evalue=6e-35,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 19564; Mature: 19564

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYNLARRAQDVTVADIIIAVDEPLDATQCGGKGACEGSKQPDGHCMTHELWSTLNQK
CCCCCHHHHHHCCCEEHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASVEPVRSVPLGPNSVFNIANS
HHHHHHCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCC
>Mature Secondary Structure
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYNLARRAQDVTVADIIIAVDEPLDATQCGGKGACEGSKQPDGHCMTHELWSTLNQK
CCCCCHHHHHHCCCEEHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASVEPVRSVPLGPNSVFNIANS
HHHHHHCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]