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The map label for this gene is cysH1 [H]

Identifier: 126453333

GI number: 126453333

Start: 992102

End: 992851

Strand: Direct

Name: cysH1 [H]

Synonym: BURPS1106A_1015

Alternate gene names: 126453333

Gene position: 992102-992851 (Clockwise)

Preceding gene: 126452080

Following gene: 126453969

Centisome position: 24.87

GC content: 69.73

Gene sequence:

>750_bases
ATGAGCGCCGCCCACGCCCCGGCCCTCACTCCGGCGCTCGCCGAGAAGAGCGCGCGGCTCGACGCGCTGCTCGCGCAAAT
CGCCGCGCGTCATCCGAAGGTCAAGTTCGCGAGCAGCCTGGCGGCCGAGGACATGCTGCTCGCCCATGCGATCCTGTCGA
AGGGCGTCGCGATCGGGATCTTTTCGCTGAACACGGGCCGCCTGCACGCGGAGACGCTCGATATGATCGAGCGCGTGCGC
GAGCGCTACGGCTACGAGATCGAGCAGTTTCATCCGCGGCAGGACGCGGTCGACGCGTATGTCGCCGAGCACGGCCTGAA
CGCGTTCTACGAGAGCGTCGAGCTACGCAAGCGCTGCTGCGAGATCCGCAAGGTCGAGCCGCTGAACCGCGCGCTCGCGG
GCGTCGACGCGTGGGTGACGGGCCAGCGGCGCGAGCAGTCGGTCACGCGCGCGGAGCTCCACGAACAGGAGCACGACGCC
GCGCGCGGGATCGCGAAATACAACCCGCTCGCGGACTGGACCGAAAGCGACGTGTGGGCCTATCTGAACGCGTTCGACGT
GCCCGTCAATCCGTTGCACGCGCGCGGCTATCCGAGCATCGGCTGTGAGCCGTGCACGCGGGCGATCCGTCCCGGCGAGG
ACAGCCGCGCGGGCCGCTGGTGGTGGGAGTCGCGCGACACGAAGGAGTGCGGGCTGCACATCACGATCACGCCGGTGCCG
GCGGACGGGGCCGAATCGGCTTGCGCCTGA

Upstream 100 bases:

>100_bases
ACGCATTCGGCGAATTCTCGCAGCGCTACCAGGGCGCGTTCGACGAGCCGGCGCCGCTGTTCCGCCGCCGCGCCGCGGCG
GCCGAAGCGAAGGTGAGCGC

Downstream 100 bases:

>100_bases
CCCGGGCCGGCACATAATAAGATAGTCAGATTGCGCCGCCGGCGAGACCGGCGGTACGAACCCAGACAAGGACCGTCATC
ATGAGCACGACGCTCGAACA

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSAAHAPALTPALAEKSARLDALLAQIAARHPKVKFASSLAAEDMLLAHAILSKGVAIGIFSLNTGRLHAETLDMIERVR
ERYGYEIEQFHPRQDAVDAYVAEHGLNAFYESVELRKRCCEIRKVEPLNRALAGVDAWVTGQRREQSVTRAELHEQEHDA
ARGIAKYNPLADWTESDVWAYLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPVP
ADGAESACA

Sequences:

>Translated_249_residues
MSAAHAPALTPALAEKSARLDALLAQIAARHPKVKFASSLAAEDMLLAHAILSKGVAIGIFSLNTGRLHAETLDMIERVR
ERYGYEIEQFHPRQDAVDAYVAEHGLNAFYESVELRKRCCEIRKVEPLNRALAGVDAWVTGQRREQSVTRAELHEQEHDA
ARGIAKYNPLADWTESDVWAYLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPVP
ADGAESACA
>Mature_248_residues
SAAHAPALTPALAEKSARLDALLAQIAARHPKVKFASSLAAEDMLLAHAILSKGVAIGIFSLNTGRLHAETLDMIERVRE
RYGYEIEQFHPRQDAVDAYVAEHGLNAFYESVELRKRCCEIRKVEPLNRALAGVDAWVTGQRREQSVTRAELHEQEHDAA
RGIAKYNPLADWTESDVWAYLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPVPA
DGAESACA

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=230, Percent_Identity=29.1304347826087, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325425, Length=112, Percent_Identity=42.8571428571429, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27591; Mature: 27460

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAHAPALTPALAEKSARLDALLAQIAARHPKVKFASSLAAEDMLLAHAILSKGVAIGI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSLNTGRLHAETLDMIERVRERYGYEIEQFHPRQDAVDAYVAEHGLNAFYESVELRKRCC
EECCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRKVEPLNRALAGVDAWVTGQRREQSVTRAELHEQEHDAARGIAKYNPLADWTESDVWA
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
YLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPVP
HHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEECCCCHHHCCEEEEEEECC
ADGAESACA
CCCCCCCCC
>Mature Secondary Structure 
SAAHAPALTPALAEKSARLDALLAQIAARHPKVKFASSLAAEDMLLAHAILSKGVAIGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSLNTGRLHAETLDMIERVRERYGYEIEQFHPRQDAVDAYVAEHGLNAFYESVELRKRCC
EECCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRKVEPLNRALAGVDAWVTGQRREQSVTRAELHEQEHDAARGIAKYNPLADWTESDVWA
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
YLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPVP
HHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEECCCCHHHCCEEEEEEECC
ADGAESACA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]