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The map label for this gene is 126453204

Identifier: 126453204

GI number: 126453204

Start: 1417876

End: 1419207

Strand: Reverse

Name: 126453204

Synonym: BURPS1106A_1459

Alternate gene names: NA

Gene position: 1419207-1417876 (Counterclockwise)

Preceding gene: 126453213

Following gene: 126454869

Centisome position: 35.58

GC content: 72.97

Gene sequence:

>1332_bases
ATGACGACCATCGACCTGAACGCGGGCGCGCTGGCGCCCGTGGCCGACGAAATCGACGCCGTCGACCTGCGCGTGACGGG
CGCGCTTGCGCGCGAGCTGAACGGCGTGCTCGTGCGCAACGGGCCCAATCCGCTGCGCGGCCGCTTCGACGGCGGCGACG
TGCTGTCGTGGTGGCCGCAGGACGCGATGCTGCACGCGATATCGTTCGACGACGGCCGCGCGACCCGCTACCGCAACCGC
TGGGCGCGCACGCGGCGCTGGGCGCGCGTGCACGATCCGGCGCGCGAGCCGTCGCTCGTCGACACGAATCCGAACGTCAA
CGTGCTCGCTCACGCGGGCGAGATTCTCGCGCTCGCCGAGGGCGGCGCGCCGCTCGCGATCACGGCCGGGCTCGACAGCA
TCGGCGCGGCGCGCCGCCACCCGGGGCTCGCGCACGGGATGGCCGCGCATCCGAAGGTCGATCCGCACACGGGCGAGCTG
ATCGCGTTTCGCGCCGACTGGAACCGGCCGTGGCTGCGCTACCTCGTCGCGGACGCGGCCGGCGCGCAGACCGTCGACAC
GGAGATCGCGCTGCCCGCGCCGTCGATGATGCACGACATCGCGATCACCGCGACGCACAGCATCGTGTTCGACCTGAACG
TCGCGTATGACTTCTCGATGCTGTCGCGCGGCCATCGGATGCCGCTGCGCTGGCACGACGCGCGCGGCGCGCGCATCGGC
GTCGTGCCGCGCCGCGGCGGCGATGCGCGCTGGTTCGACATCGCGCCGTGCTTCATTCAGCACGTCGTCAACGCATACGA
TCTCGACCGCCCGGCGATCGTGCTGGACGTGGTCCGCTATCCGTGGTTCCTGCGCGTCGCCCGCGACGGGCGCGGCTTCG
ACGACAACCCGCCCGGCGTGCTGTGGCGCTACGTGATCGATCTCGTGACGGGCACCGTCGCCGAGCAGCCGCTCGACGAC
GCCGGCATCGAGCTGCCCCGGATCGACGCGCGCCGCACCGGGCGCCGCCACCGGTTCCTGTACGCGGCCGAGCAGCCGAC
CCCCGTGGAGCTGCGCGGCATCGTGCGCTACGACCTCGACGGCGGCTCGACGCAGCGCTACCGGGTGCCGCCCGGCGACC
AGAACAGCGAGCCCGTGTTCGTCCCGCGTCCGGGCGCGGCGGGCGAAGACGACGGCTGGCTGCTCGTCTGCGTGTATCGC
CATGCAACGGATACGAGCGACGTCGTGATCCTCGACGGCCGGTCGATCGGCGACGGGCCGATCGCGACCGTGCACCTGCC
GCGCCGCGTCCCGGCGGGTTTTCATGGCGCGTGGCTGCCGGCCGGCGCATGA

Upstream 100 bases:

>100_bases
GGCCGACGTGCGCGACCACGCGCTCGCGCTCGCGCTCGCGTCGCCGGATGACGGCGCGCCGTTGCCCGAGGTTCGCTGAC
GCCCCGCCCCGAGACCTCCG

Downstream 100 bases:

>100_bases
GCGAAAACGCCGCGCCGCGCGGCGAGCCGAGCCGAGCCGACACGACGCAAGAGCGGAATCGAAAACGGCGACGGCCGCGC
GAATCGCGCACCGCCTGCGG

Product: putative carotenoid 9,10-9',10' cleavage dioxygenase

Products: NA

Alternate protein names: ACO; 8'-apo-beta-carotenal 15,15'-oxygenase; Diox1 [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MTTIDLNAGALAPVADEIDAVDLRVTGALARELNGVLVRNGPNPLRGRFDGGDVLSWWPQDAMLHAISFDDGRATRYRNR
WARTRRWARVHDPAREPSLVDTNPNVNVLAHAGEILALAEGGAPLAITAGLDSIGAARRHPGLAHGMAAHPKVDPHTGEL
IAFRADWNRPWLRYLVADAAGAQTVDTEIALPAPSMMHDIAITATHSIVFDLNVAYDFSMLSRGHRMPLRWHDARGARIG
VVPRRGGDARWFDIAPCFIQHVVNAYDLDRPAIVLDVVRYPWFLRVARDGRGFDDNPPGVLWRYVIDLVTGTVAEQPLDD
AGIELPRIDARRTGRRHRFLYAAEQPTPVELRGIVRYDLDGGSTQRYRVPPGDQNSEPVFVPRPGAAGEDDGWLLVCVYR
HATDTSDVVILDGRSIGDGPIATVHLPRRVPAGFHGAWLPAGA

Sequences:

>Translated_443_residues
MTTIDLNAGALAPVADEIDAVDLRVTGALARELNGVLVRNGPNPLRGRFDGGDVLSWWPQDAMLHAISFDDGRATRYRNR
WARTRRWARVHDPAREPSLVDTNPNVNVLAHAGEILALAEGGAPLAITAGLDSIGAARRHPGLAHGMAAHPKVDPHTGEL
IAFRADWNRPWLRYLVADAAGAQTVDTEIALPAPSMMHDIAITATHSIVFDLNVAYDFSMLSRGHRMPLRWHDARGARIG
VVPRRGGDARWFDIAPCFIQHVVNAYDLDRPAIVLDVVRYPWFLRVARDGRGFDDNPPGVLWRYVIDLVTGTVAEQPLDD
AGIELPRIDARRTGRRHRFLYAAEQPTPVELRGIVRYDLDGGSTQRYRVPPGDQNSEPVFVPRPGAAGEDDGWLLVCVYR
HATDTSDVVILDGRSIGDGPIATVHLPRRVPAGFHGAWLPAGA
>Mature_442_residues
TTIDLNAGALAPVADEIDAVDLRVTGALARELNGVLVRNGPNPLRGRFDGGDVLSWWPQDAMLHAISFDDGRATRYRNRW
ARTRRWARVHDPAREPSLVDTNPNVNVLAHAGEILALAEGGAPLAITAGLDSIGAARRHPGLAHGMAAHPKVDPHTGELI
AFRADWNRPWLRYLVADAAGAQTVDTEIALPAPSMMHDIAITATHSIVFDLNVAYDFSMLSRGHRMPLRWHDARGARIGV
VPRRGGDARWFDIAPCFIQHVVNAYDLDRPAIVLDVVRYPWFLRVARDGRGFDDNPPGVLWRYVIDLVTGTVAEQPLDDA
GIELPRIDARRTGRRHRFLYAAEQPTPVELRGIVRYDLDGGSTQRYRVPPGDQNSEPVFVPRPGAAGEDDGWLLVCVYRH
ATDTSDVVILDGRSIGDGPIATVHLPRRVPAGFHGAWLPAGA

Specific function: Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. Also shows activity toward lycopenals and the corresponding alcohols. Does not cleave beta- carotene or lyco

COG id: COG3670

COG function: function code Q; Lignostilbene-alpha,beta-dioxygenase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004294 [H]

Pfam domain/function: PF03055 RPE65 [H]

EC number: =1.14.99.41 [H]

Molecular weight: Translated: 48618; Mature: 48486

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIDLNAGALAPVADEIDAVDLRVTGALARELNGVLVRNGPNPLRGRFDGGDVLSWWPQ
CEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCC
DAMLHAISFDDGRATRYRNRWARTRRWARVHDPAREPSLVDTNPNVNVLAHAGEILALAE
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEECCEEEEEEC
GGAPLAITAGLDSIGAARRHPGLAHGMAAHPKVDPHTGELIAFRADWNRPWLRYLVADAA
CCCCEEEECCCCHHCHHHCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCC
GAQTVDTEIALPAPSMMHDIAITATHSIVFDLNVAYDFSMLSRGHRMPLRWHDARGARIG
CCEECCCEEECCCCHHHHEEEEEEEEEEEEEEEEEEEHHHHHCCCCCCEEEECCCCCEEE
VVPRRGGDARWFDIAPCFIQHVVNAYDLDRPAIVLDVVRYPWFLRVARDGRGFDDNPPGV
EEECCCCCCCEEECHHHHHHHHHHHHCCCCCCEEEEHHHCCEEEEEECCCCCCCCCCCHH
LWRYVIDLVTGTVAEQPLDDAGIELPRIDARRTGRRHRFLYAAEQPTPVELRGIVRYDLD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCEEEEEEEEEECC
GGSTQRYRVPPGDQNSEPVFVPRPGAAGEDDGWLLVCVYRHATDTSDVVILDGRSIGDGP
CCCCCEEECCCCCCCCCCEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCCC
IATVHLPRRVPAGFHGAWLPAGA
EEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTIDLNAGALAPVADEIDAVDLRVTGALARELNGVLVRNGPNPLRGRFDGGDVLSWWPQ
EEEECCCCCCCCCCCCCCEEEEEEHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCC
DAMLHAISFDDGRATRYRNRWARTRRWARVHDPAREPSLVDTNPNVNVLAHAGEILALAE
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEECCEEEEEEC
GGAPLAITAGLDSIGAARRHPGLAHGMAAHPKVDPHTGELIAFRADWNRPWLRYLVADAA
CCCCEEEECCCCHHCHHHCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCC
GAQTVDTEIALPAPSMMHDIAITATHSIVFDLNVAYDFSMLSRGHRMPLRWHDARGARIG
CCEECCCEEECCCCHHHHEEEEEEEEEEEEEEEEEEEHHHHHCCCCCCEEEECCCCCEEE
VVPRRGGDARWFDIAPCFIQHVVNAYDLDRPAIVLDVVRYPWFLRVARDGRGFDDNPPGV
EEECCCCCCCEEECHHHHHHHHHHHHCCCCCCEEEEHHHCCEEEEEECCCCCCCCCCCHH
LWRYVIDLVTGTVAEQPLDDAGIELPRIDARRTGRRHRFLYAAEQPTPVELRGIVRYDLD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCEEEEEEEEEECC
GGSTQRYRVPPGDQNSEPVFVPRPGAAGEDDGWLLVCVYRHATDTSDVVILDGRSIGDGP
CCCCCEEECCCCCCCCCCEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCCC
IATVHLPRRVPAGFHGAWLPAGA
EEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]