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The map label for this gene is groES

Identifier: 126453024

GI number: 126453024

Start: 3075213

End: 3075506

Strand: Reverse

Name: groES

Synonym: BURPS1106A_3154

Alternate gene names: 126453024

Gene position: 3075506-3075213 (Counterclockwise)

Preceding gene: 126454813

Following gene: 126452878

Centisome position: 77.11

GC content: 60.54

Gene sequence:

>294_bases
ATGAACCTTCGTCCGTTGCACGATCGCGTGATCGTCAAGCGCCTGGATCAGGAAACCAAGACCGCCTCGGGCATCGTCAT
TCCCGACGCAGCCGCTGAGAAGCCGGATCAAGGCGAAGTCCTGGCCATCGGCCCGGGCAAGCGCGATGACAAGGGCGCTC
CGATCGCACTCGACGTGAAGGTCGGCGATCGTGTTCTGTTCGGCAAGTACGCTGGCCAAACCGTCAAGGTCGACGGCCAG
GAACTGCTCGTGATGCGCGAAGAAGACATCATGGCCGTGGTCAACGCTAAGTAA

Upstream 100 bases:

>100_bases
GCACTCGCTGCACGAGAGTGCTAACAATTCCTGCCGGTCGGCGAGCCGTCCGGTAGTTTCCCTCAGCGTTCTTCAGTCTC
AATCAAAGAGAGGAGTGAAT

Downstream 100 bases:

>100_bases
GCGTTCGCCAACGGATCACAATCTCAGAGAATTCAAGGAGTTAGAAGATGGCAGCTAAAGACGTCGTATTCGGCGATTCC
GCACGCGCGAAGATGGTCGA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAIGPGKRDDKGAPIALDVKVGDRVLFGKYAGQTVKVDGQ
ELLVMREEDIMAVVNAK

Sequences:

>Translated_97_residues
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAIGPGKRDDKGAPIALDVKVGDRVLFGKYAGQTVKVDGQ
ELLVMREEDIMAVVNAK
>Mature_97_residues
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAIGPGKRDDKGAPIALDVKVGDRVLFGKYAGQTVKVDGQ
ELLVMREEDIMAVVNAK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=97, Percent_Identity=53.6082474226804, Blast_Score=99, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=41.4893617021277, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=42.6966292134831, Blast_Score=78, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356029, Length=91, Percent_Identity=43.956043956044, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358317, Length=90, Percent_Identity=43.3333333333333, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_BURCE (Q9ZFE1)

Other databases:

- EMBL:   AF104907
- ProteinModelPortal:   Q9ZFE1
- SMR:   Q9ZFE1
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10490; Mature: 10490

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAIGPGKRDDKGAPIALDVK
CCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEE
VGDRVLFGKYAGQTVKVDGQELLVMREEDIMAVVNAK
ECCEEEEECCCCCEEEECCCEEEEECCCCEEEEEECC
>Mature Secondary Structure
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAIGPGKRDDKGAPIALDVK
CCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEE
VGDRVLFGKYAGQTVKVDGQELLVMREEDIMAVVNAK
ECCEEEEECCCCCEEEECCCEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA