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The map label for this gene is insK [H]

Identifier: 126452763

GI number: 126452763

Start: 1673775

End: 1674611

Strand: Reverse

Name: insK [H]

Synonym: BURPS1106A_1714

Alternate gene names: 126452763

Gene position: 1674611-1673775 (Counterclockwise)

Preceding gene: 126453991

Following gene: 126451727

Centisome position: 41.99

GC content: 57.59

Gene sequence:

>837_bases
GTGCTCGAATTGAGGCAGCACCATCCACTGTCGATCCTGCTGAACGTGGCGGGATTGGCGCGTAGTACCTTTTACTATCA
GCAGAAGGTGCTTCTGGCCGGGGATCGCTACGCCGCACTCAAGCAGCGCATCCGGGCGATCTATGAATCTCACCGGGGCC
GTTATGGCTACCGGCGCATCACGGCGGTCATCCGGCAAGCGGGGACACCGGTCAACCACAAGCTGGTCCGGCGCCTGATG
CTTCAACTCGGCTTGAAGTCGCTGGTGCGAGCGAAGAAGTATCGTTCCTGGCGGGGAATGGTGGGTTGTGTCGCGCCGAA
CTTGCTCAACCGGCAGTTCAAGGCGGAACGCCTCAACCAGAAATGGGTGACCGACGTCACGGAATTCAACGTGAAAGGCC
AGAAGCTTTACCTGTCACCGGTGATGGACTTGTATAACGGCGAAATCATCGCCTGGCACAGTGCTACCCGAGCGAGCTTC
GATTTGATCAGCAGCATGCTCAAGAAGGCCTTCTCAAGGCTGACGCGCGGTGAACGTCCGTTGCTGCATTCGGATCAGGG
CTGGCAGTACCAAATGCCAGCCTATCGTCGCTTGCTGGATCAGCGCGCCGTTCAACAGAGCATGTCACGCAAAGGCAACT
GCCTGGACAATGCCGCCATGGAGAGCTTCTTTGGTACCCTCAAGGCGGAGTTTTTCCACCTCAACGAGTTCGACAGCGTC
GAACAATTGCAGGCCGGAATCCGGCAGTACATCCGTTACTACAACCACGAACGCATCCGGCTGAAGTTGAAAGCGCTGAG
TCCTGTTCAATACAGAACCCAGCCCCTGCTGGCCTAG

Upstream 100 bases:

>100_bases
AGGAAGTTGAGTACCTGCGCGCGGAGGTAGCCTACCTAAAAAAACTCGATGCCTTGATTCGGGCGGAGCAACGTCAGACA
CGACGCGCAAAGCGCAAGTA

Downstream 100 bases:

>100_bases
CACTCCTGAACCGTCCAACTTCTGGGGTTCAGTTCACCTCGGCGCCCGTTTTCGTTTTGATGCCGTTTTGATGCCGTTTC
GATCCCGGCATCGCGCGCCG

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MLELRQHHPLSILLNVAGLARSTFYYQQKVLLAGDRYAALKQRIRAIYESHRGRYGYRRITAVIRQAGTPVNHKLVRRLM
LQLGLKSLVRAKKYRSWRGMVGCVAPNLLNRQFKAERLNQKWVTDVTEFNVKGQKLYLSPVMDLYNGEIIAWHSATRASF
DLISSMLKKAFSRLTRGERPLLHSDQGWQYQMPAYRRLLDQRAVQQSMSRKGNCLDNAAMESFFGTLKAEFFHLNEFDSV
EQLQAGIRQYIRYYNHERIRLKLKALSPVQYRTQPLLA

Sequences:

>Translated_278_residues
MLELRQHHPLSILLNVAGLARSTFYYQQKVLLAGDRYAALKQRIRAIYESHRGRYGYRRITAVIRQAGTPVNHKLVRRLM
LQLGLKSLVRAKKYRSWRGMVGCVAPNLLNRQFKAERLNQKWVTDVTEFNVKGQKLYLSPVMDLYNGEIIAWHSATRASF
DLISSMLKKAFSRLTRGERPLLHSDQGWQYQMPAYRRLLDQRAVQQSMSRKGNCLDNAAMESFFGTLKAEFFHLNEFDSV
EQLQAGIRQYIRYYNHERIRLKLKALSPVQYRTQPLLA
>Mature_278_residues
MLELRQHHPLSILLNVAGLARSTFYYQQKVLLAGDRYAALKQRIRAIYESHRGRYGYRRITAVIRQAGTPVNHKLVRRLM
LQLGLKSLVRAKKYRSWRGMVGCVAPNLLNRQFKAERLNQKWVTDVTEFNVKGQKLYLSPVMDLYNGEIIAWHSATRASF
DLISSMLKKAFSRLTRGERPLLHSDQGWQYQMPAYRRLLDQRAVQQSMSRKGNCLDNAAMESFFGTLKAEFFHLNEFDSV
EQLQAGIRQYIRYYNHERIRLKLKALSPVQYRTQPLLA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=209, Percent_Identity=28.7081339712919, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1789981, Length=272, Percent_Identity=54.4117647058823, Blast_Score=322, Evalue=1e-89,
Organism=Escherichia coli, GI1788405, Length=236, Percent_Identity=34.3220338983051, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787263, Length=236, Percent_Identity=34.3220338983051, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786753, Length=236, Percent_Identity=34.3220338983051, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786570, Length=236, Percent_Identity=34.3220338983051, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786490, Length=236, Percent_Identity=34.3220338983051, Blast_Score=121, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32507; Mature: 32507

Theoretical pI: Translated: 11.00; Mature: 11.00

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]