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The map label for this gene is ydcR [H]

Identifier: 126452657

GI number: 126452657

Start: 1427186

End: 1428667

Strand: Reverse

Name: ydcR [H]

Synonym: BURPS1106A_1468

Alternate gene names: 126452657

Gene position: 1428667-1427186 (Counterclockwise)

Preceding gene: 126452375

Following gene: 126453957

Centisome position: 35.82

GC content: 69.77

Gene sequence:

>1482_bases
TTGTCGATGAAACGTTACGAAACGCTCGCCCGCGCGATGGCCGACGACATCCGGTCCGGCAACATCACGACCGGCACGCG
CATGCCGTCGCTGCGCCAGATGATCGCCCAGCATCGCGTCAGCCAATCGACCGTGTTTCGTGCTTACTATCTGCTCGAGC
AGTGGGGCTTGATTCGCGCGCGCGAACGCTCGGGCTACTACGTCGCGCACGGCGCGCAGGCGAGCGTCCGCGCGAACGGC
ATGAACGGCATGAATGGTGCGCACGCGACGCAAGACGGCCGTCTCACGCGCGATGCCGCGCCCGCCGAATCGCGCAAGGT
CGATATCAGCGATCTCGTGTTCTCCGTGCTCGAGGCCGCGACGCATCCGCGCATCGTGCCGCTCGGCTCCGCGTTCGCCT
CGCCGCATCTGTTTCCGCTGCCGCGCCTCGCGAAGTCGCTCGCGCAGGCCGCACGGCTCGTGAGCCCGTGGAGCGCCGTC
GTCGATCTGCCGCCCGGCAGCGAGCAGTTGCGCCGCCAGATCGCGTTGCGCTACCTCGGCATCGGCGTGTCGCAGCCGAT
CGACGAGATCGTCGTGACCAACGGCGCGCTCGAGGCGCTCAACCTGTGCCTGACGGCCGTCACGCGCCCCGGCGACGTGG
TCGCCGTCGAAGCGCCCGGCTTCTATGCGGCGCTGCAGGCAATCGAGCGGCTCGATCTGCGCGCGGTCGAGATTCCCGTC
GATCCGCGCACGGGCCTCGACCTCGACGCGCTCGCCGCCGCGCTCGAACGCCACGACGTGCGCGCGTGCTGGTTCATGAC
GAACTTCCAGAATCCGACGGGCGTCACGCTGTCGGCCGACAAGAAGAAGGCGCTCGTCGACATGCTCGCCGCGCGCGAGG
TGCCGCTCATCGAGGACGACGTCTACGGCGAGCTGCATCACGGGCCGGACTACCCGCTGCCCGCGCGCGCGTTCGACAAG
CACGGGCTCGTCATGCACTGCAGCTCGTTCTCGAAGACGCTCGCGCCCGGCTACCGGATCGGCTGGGCGGCGGCCGGGCG
CTTCGCCGAGAAGGTGCAGCGGCTCAAGCTGATGACGACGCTGTCCGCGAGCATTCCCGCGCAGGTCGGCATCGCCGACT
ATCTCGAGCACGGCGGCTACGATCGGCACCTGCGCAAGCTGCGCGGCGCGCTGCGCGGGCAGATGGAGCGGATGAACGAC
GCGTTGATGCGCCATCTGCCGCCCGACGTGCACTGGACGCTGCCGGACGGCGGCTACTTCGTGTGGCTGGAATTTCCCGA
CGCGATCGACGCGATGGGGCTGCATCGCGAAGCGATCCGGCGCGGCGTGAGCGTCGCGCCCGGGCCGCTCTTCTCCGCCG
CGCATGCGTTCGAGCGCTGCGTGCGGATCAACTTCGGCCACCCGTGGAGCGCCGCCGTCGACGACGCGATCCGCACCGTC
GGCGAGCTGGTCGCGCAGCCGTCGGTGCGCAAGCGGCGCTGA

Upstream 100 bases:

>100_bases
GCCCACGGCGTCGCCTCCCGATCGCGCCGCGCCTTTCCTTTTACTGCACCGCATAAGACAATATGCGACCCGTGCCGGCG
CACCCTTCCCCAACCTGCCC

Downstream 100 bases:

>100_bases
CGCGCGACGCGGCGCGAGCGACACGAGCGGCCCGCCGCGCGCGCGGCCGACGGCCGTGCCGGGCGACGCGCACCGCTCAG
TGAATCACGGTAATCGCGAC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MSMKRYETLARAMADDIRSGNITTGTRMPSLRQMIAQHRVSQSTVFRAYYLLEQWGLIRARERSGYYVAHGAQASVRANG
MNGMNGAHATQDGRLTRDAAPAESRKVDISDLVFSVLEAATHPRIVPLGSAFASPHLFPLPRLAKSLAQAARLVSPWSAV
VDLPPGSEQLRRQIALRYLGIGVSQPIDEIVVTNGALEALNLCLTAVTRPGDVVAVEAPGFYAALQAIERLDLRAVEIPV
DPRTGLDLDALAAALERHDVRACWFMTNFQNPTGVTLSADKKKALVDMLAAREVPLIEDDVYGELHHGPDYPLPARAFDK
HGLVMHCSSFSKTLAPGYRIGWAAAGRFAEKVQRLKLMTTLSASIPAQVGIADYLEHGGYDRHLRKLRGALRGQMERMND
ALMRHLPPDVHWTLPDGGYFVWLEFPDAIDAMGLHREAIRRGVSVAPGPLFSAAHAFERCVRINFGHPWSAAVDDAIRTV
GELVAQPSVRKRR

Sequences:

>Translated_493_residues
MSMKRYETLARAMADDIRSGNITTGTRMPSLRQMIAQHRVSQSTVFRAYYLLEQWGLIRARERSGYYVAHGAQASVRANG
MNGMNGAHATQDGRLTRDAAPAESRKVDISDLVFSVLEAATHPRIVPLGSAFASPHLFPLPRLAKSLAQAARLVSPWSAV
VDLPPGSEQLRRQIALRYLGIGVSQPIDEIVVTNGALEALNLCLTAVTRPGDVVAVEAPGFYAALQAIERLDLRAVEIPV
DPRTGLDLDALAAALERHDVRACWFMTNFQNPTGVTLSADKKKALVDMLAAREVPLIEDDVYGELHHGPDYPLPARAFDK
HGLVMHCSSFSKTLAPGYRIGWAAAGRFAEKVQRLKLMTTLSASIPAQVGIADYLEHGGYDRHLRKLRGALRGQMERMND
ALMRHLPPDVHWTLPDGGYFVWLEFPDAIDAMGLHREAIRRGVSVAPGPLFSAAHAFERCVRINFGHPWSAAVDDAIRTV
GELVAQPSVRKRR
>Mature_492_residues
SMKRYETLARAMADDIRSGNITTGTRMPSLRQMIAQHRVSQSTVFRAYYLLEQWGLIRARERSGYYVAHGAQASVRANGM
NGMNGAHATQDGRLTRDAAPAESRKVDISDLVFSVLEAATHPRIVPLGSAFASPHLFPLPRLAKSLAQAARLVSPWSAVV
DLPPGSEQLRRQIALRYLGIGVSQPIDEIVVTNGALEALNLCLTAVTRPGDVVAVEAPGFYAALQAIERLDLRAVEIPVD
PRTGLDLDALAAALERHDVRACWFMTNFQNPTGVTLSADKKKALVDMLAAREVPLIEDDVYGELHHGPDYPLPARAFDKH
GLVMHCSSFSKTLAPGYRIGWAAAGRFAEKVQRLKLMTTLSASIPAQVGIADYLEHGGYDRHLRKLRGALRGQMERMNDA
LMRHLPPDVHWTLPDGGYFVWLEFPDAIDAMGLHREAIRRGVSVAPGPLFSAAHAFERCVRINFGHPWSAAVDDAIRTVG
ELVAQPSVRKRR

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=395, Percent_Identity=23.7974683544304, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI33469970, Length=395, Percent_Identity=23.7974683544304, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4507369, Length=175, Percent_Identity=24.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787710, Length=484, Percent_Identity=46.6942148760331, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1790797, Length=492, Percent_Identity=34.1463414634146, Blast_Score=276, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6321000, Length=289, Percent_Identity=22.1453287197232, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54189; Mature: 54058

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMKRYETLARAMADDIRSGNITTGTRMPSLRQMIAQHRVSQSTVFRAYYLLEQWGLIRA
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RERSGYYVAHGAQASVRANGMNGMNGAHATQDGRLTRDAAPAESRKVDISDLVFSVLEAA
ECCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
THPRIVPLGSAFASPHLFPLPRLAKSLAQAARLVSPWSAVVDLPPGSEQLRRQIALRYLG
CCCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHHHHC
IGVSQPIDEIVVTNGALEALNLCLTAVTRPGDVVAVEAPGFYAALQAIERLDLRAVEIPV
CCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEECC
DPRTGLDLDALAAALERHDVRACWFMTNFQNPTGVTLSADKKKALVDMLAAREVPLIEDD
CCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCC
VYGELHHGPDYPLPARAFDKHGLVMHCSSFSKTLAPGYRIGWAAAGRFAEKVQRLKLMTT
CCCCCCCCCCCCCCCHHHCCCCEEEEECHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
LSASIPAQVGIADYLEHGGYDRHLRKLRGALRGQMERMNDALMRHLPPDVHWTLPDGGYF
HHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEE
VWLEFPDAIDAMGLHREAIRRGVSVAPGPLFSAAHAFERCVRINFGHPWSAAVDDAIRTV
EEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GELVAQPSVRKRR
HHHHCCCCHHCCC
>Mature Secondary Structure 
SMKRYETLARAMADDIRSGNITTGTRMPSLRQMIAQHRVSQSTVFRAYYLLEQWGLIRA
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RERSGYYVAHGAQASVRANGMNGMNGAHATQDGRLTRDAAPAESRKVDISDLVFSVLEAA
ECCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
THPRIVPLGSAFASPHLFPLPRLAKSLAQAARLVSPWSAVVDLPPGSEQLRRQIALRYLG
CCCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHHHHC
IGVSQPIDEIVVTNGALEALNLCLTAVTRPGDVVAVEAPGFYAALQAIERLDLRAVEIPV
CCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEECC
DPRTGLDLDALAAALERHDVRACWFMTNFQNPTGVTLSADKKKALVDMLAAREVPLIEDD
CCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCC
VYGELHHGPDYPLPARAFDKHGLVMHCSSFSKTLAPGYRIGWAAAGRFAEKVQRLKLMTT
CCCCCCCCCCCCCCCHHHCCCCEEEEECHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
LSASIPAQVGIADYLEHGGYDRHLRKLRGALRGQMERMNDALMRHLPPDVHWTLPDGGYF
HHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEE
VWLEFPDAIDAMGLHREAIRRGVSVAPGPLFSAAHAFERCVRINFGHPWSAAVDDAIRTV
EEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GELVAQPSVRKRR
HHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]