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The map label for this gene is sir1 [H]

Identifier: 126453957

GI number: 126453957

Start: 1424499

End: 1426400

Strand: Reverse

Name: sir1 [H]

Synonym: BURPS1106A_1466

Alternate gene names: 126453957

Gene position: 1426400-1424499 (Counterclockwise)

Preceding gene: 126452657

Following gene: 126452923

Centisome position: 35.76

GC content: 70.66

Gene sequence:

>1902_bases
TTGGTGATCCTCGCGCCGCCGATGCGGCGCCTCGCAACCGACACGCGCGACCGCGCGCGTGCCGCCCCACCGCATTGCCC
GGCCATGTACCGATACACCGAATTCGACAAGGCGTTCGTGCGCAACCGCGCCGCCCAGTTTCGCGATCAGCTCGAACGCT
GGCGGCAAGGCGCGCTCAGCGAGGACGCATTCCGCCCGCTGCGGCTGCAGAACGGCTGGTATGTGCAGCGCCATGCGCCG
ATGCTGCGCGTCGCGGTGCCGTACGGCGAGCTGTCGAGCGCGCAGATCCGCATGCTCGCGCGCATCGCGCGCGACTATGA
CGTGCCGGAGCCGGCGCGCTACCGCGCCGCGTGCGACGCGCAGGCGCGGCTCGGCACCGTGCGCCTGCCGACGCGCAACG
CGCATTTCACGACGCGCACGAACGTGCAGTTCAACTGGATCCCGCTCGAGAAGGCGGCCGACGTGATGGACCTGCTCGCG
ACCGTCGACATGCACGGCATCCAGACGAGCGGCAACTGCATCCGCAACATCTCGTGCGACGAGCGCGCGGGCGTCGCGCC
CGACGAAATCGCCGATCCGCGGCCGTTCGCCGAAGTGATGCGCCAATGGACGACGCTGCATCCCGAATTCGCGTTCCTGC
CGCGCAAGTTCAAGATCGCGATCACGGGCGCGGCCGACGATCGCGCGGCGACCGACTGGCACGATGTCGGCTTAAGGCTC
GTGCGCGACGCGGCGGGCGAACTCGGCTTTCGCGTGAGCGTCGGCGGCGGCATGGGGCGCACGCCGATGACGGCCACGCT
CGTGCGCGCATTCGTGCCGTGGCGGCACGTGATGAACTACATCGAGGCGATCGTGCGCGTGTACAACCGCTACGGCCGCC
GCGACAACAGGTACAAGGCGCGCATCAAGATCCTCGTGAAGGCCGAGGGCCAGCGCTACATCGACGACGTCGACGAGGAA
TTCCGGCAGATCGTCGAGCACGACGGCGGCCCGCATACGATCGAGCAGGCGGAGTTCGACCGCGTAGGCGCGTCGTTCGT
GCCGCCCGTGCCGCCGCCGTGCGCGGCCGGGCGCCACGCAAAGACCGATATCGACGCCGACATGGACGCGGCGCTCGCGC
GCATGCGCACGCTCGCCGGCGCACAGCCCGCGTTCGCGCGCTGGCTCGAGCGCAACGTCGCGCCGCACCGGGATCCCGCG
CGGCGGATCGTCACGCTGTCGTTCAAGCGCAGGCATCAGGCGCCCGGCGATGCGTCGCCCGAGCAGCTCGACGCGCTCGC
GCACCTCGCCGAGCGCTTTTCCGCCGGCGAGGCGCGCGTCACGCACGCGCAGAACGTCGTGCTGCCGTGGGTGCGCGCGA
TCGATCTGCACGCGCTGTGGGAGGCCGCGCGCGACGCGGGCCTCGCGAGCGCGAACGTGCGGCTGTTGACCGACATGATC
GCGTGCCCCGGCGGCGATTTCTGCGCGCTCGCGAACGCGCGCTCGATCCCGATCGCCGATGCGATCGCCGAACGCTTCGA
CGATCTCGACGAGTTGCACGACATCGGCGACGTCGACCTGCACGTGAGCGGCTGCATCAACTCGTGCGGCCATCATCACA
GCGGCCACATCGGCATCCTCGGCGTCGACAAGGACGGCGACGAGTGGTACCAGGTGACGCTCGGCGGCTCCGACGGCACG
GCCGCGAACGGCCCCGCGCAGCCGGGCAAGGTGATCGGGCCGTCGTTCTCGGCCGACGAGATCGTCGACGTCGTCGACGC
GCTCGTCGCCACCTATCTGCGCGTGCGGCGAACCGAGGCCGGGCGCGTCGAACGCTTCATCGACGCGTACCGCCGCGTCG
GCCCCGAGCCCTTCAAGGCCGCCGCGAACGCGGCGCGCCATCCCGAGACGAGTGTCGCATGA

Upstream 100 bases:

>100_bases
TTCGACCTCGGGCGCGACCGCCCTACGCGCGCCCGCCGCATCTGCTGCGCAAAATCCGTCCGAATCTGCTGCTTGTTGCG
CGCGGCCGCGCGCCCTACGC

Downstream 100 bases:

>100_bases
GCCCGCCGAACCGCATCCGCCTGCTGAGCGCGAGCGCCCACGGCGACGAAACGCGCGCCGCGCCCGCCCGCGACGGCGCG
CCGCTCGCCATCGCGAACGA

Product: sulfite reductase, beta subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAP
MLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLA
TVDMHGIQTSGNCIRNISCDERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL
VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEE
FRQIVEHDGGPHTIEQAEFDRVGASFVPPVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPA
RRIVTLSFKRRHQAPGDASPEQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI
ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGT
AANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHPETSVA

Sequences:

>Translated_633_residues
MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAP
MLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLA
TVDMHGIQTSGNCIRNISCDERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL
VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEE
FRQIVEHDGGPHTIEQAEFDRVGASFVPPVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPA
RRIVTLSFKRRHQAPGDASPEQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI
ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGT
AANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHPETSVA
>Mature_633_residues
MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAP
MLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLA
TVDMHGIQTSGNCIRNISCDERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL
VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEE
FRQIVEHDGGPHTIEQAEFDRVGASFVPPVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPA
RRIVTLSFKRRHQAPGDASPEQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI
ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGT
AANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHPETSVA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 70249; Mature: 70249

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALS
CEEECCCHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EDAFRPLRLQNGWYVQRHAPMLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDA
CCCCCCEEECCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCC
QARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLATVDMHGIQTSGNCIRNISCD
HHHCCEEECCCCCCCEEEECCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
ERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL
CCCCCCCHHCCCCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCCCCCHHHHHHHH
VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKA
HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
RIKILVKAEGQRYIDDVDEEFRQIVEHDGGPHTIEQAEFDRVGASFVPPVPPPCAAGRHA
EEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
KTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPARRIVTLSFKRRHQAPGDASP
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHEEEEEHHHHCCCCCCCCH
EQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI
HHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGIL
HCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCEEEE
GVDKDGDEWYQVTLGGSDGTAANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEA
EECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
GRVERFIDAYRRVGPEPFKAAANAARHPETSVA
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALS
CEEECCCHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EDAFRPLRLQNGWYVQRHAPMLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDA
CCCCCCEEECCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCC
QARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLATVDMHGIQTSGNCIRNISCD
HHHCCEEECCCCCCCEEEECCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
ERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL
CCCCCCCHHCCCCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCCCCCHHHHHHHH
VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKA
HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
RIKILVKAEGQRYIDDVDEEFRQIVEHDGGPHTIEQAEFDRVGASFVPPVPPPCAAGRHA
EEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
KTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPARRIVTLSFKRRHQAPGDASP
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHEEEEEHHHHCCCCCCCCH
EQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI
HHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGIL
HCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCEEEE
GVDKDGDEWYQVTLGGSDGTAANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEA
EECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
GRVERFIDAYRRVGPEPFKAAANAARHPETSVA
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA