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The map label for this gene is cbaA [H]

Identifier: 126452501

GI number: 126452501

Start: 1327853

End: 1329478

Strand: Direct

Name: cbaA [H]

Synonym: BURPS1106A_1359

Alternate gene names: 126452501

Gene position: 1327853-1329478 (Clockwise)

Preceding gene: 126451681

Following gene: 126451594

Centisome position: 33.29

GC content: 65.62

Gene sequence:

>1626_bases
GTGTTAAAGAATAATCGACTGGTGCTCGCGCACTTCTGGCTCGCGTTCGCGGTCTTCGGCGTCGCGCTGTTGCTCGGCGC
GTGGCAGATGCTCGCGCGCAGCCCGCTGCATCCGTGGCTCGGCAATCCCGAGCTCTACTACCGCTCGGTGACGGCGCACG
GCTCCGTGATGGGCTATGTGTTTCCGACGCTGATCGCGATGGGTTTCGGCTACGCGATCAGCGAGCTCGCGCTGAAGATG
CCGCTCGTCGGCCGCCGCTGGGCATGGACGGGCTTCTGGCTGATCGGGCTCGGCTCGGTCGTCGCGATGACGCCCGTGTC
GCTCGGCCTGTCGTCGGTGCTGTATACGTTCTATCCGCCGATGATCGGCAGCCCGTTCTACTACCTCGGCGTCGTGCTCG
TCGTCGTCGGCTCGTGGATCTGGGTCGCGCTGATGTCGGTGAACCTCTATGCGTGGAAGAAGCGCAATCCCGGCACGCCG
ATTCCGCTCGCGATGTTCGCCAACGTCGCGGGCGCGTATCTGTGGGGCTGGACCGCGGTGGGCGCCGCGATCGAGATCCT
GTTCCAGATCCTGCCCGTCGCGGTCGGCCTGAAGACGACGATCGACGCGGGCCTCGCGCGCGTGTTCTTCTCGTGGACGC
TGCACGCGATCGTCTACTTCTGGCTGATTCCCGCGTACATCGCGTACTACACGCTCGTGCCGCGCGCGATCGGCGGCAAG
CTGTACAGCGACGGGATGGCGCGCATCTCGTTCATCCTGTTCCTCGTCGGCGCGATGCCGATCGGCGTGCACCACCTGTT
CGCCGATCCGCAGGTCGGCTCGGGCTTCAAGTTCCTGCAATCGGTGTTCACCGCGCTCGTCGCGGTGCCGACGCTGCTCA
CGGTATTTACGGTGTGCGCATCGGTCGAGATCGCCGCGCGCCTGCGCGGCGGCAAGGGCGCGTTCGGCTGGCTGCGCGCG
CTGCCCTGGCACGAGCCGATGATGCTCGCCGTCGCGTTCTCGTTCGTGATGCTCGGCTTCGGCGGCGCGGGGGGGCTCAT
CAACATGAGCTATCAGCTCGATTCGACGATCCACAACACGCAGTGGATCACCGGGCACTTTCACCTGATCTTCGGCGGCG
CCGTCGTCATCATGTACTTCGCGATCGCGTATGAACTGTGGCCGCATCTGACGGGCCGCGCGCTCGGCAGCCTGCGGCTC
GTGAAGGCGCAGCTCTGGCTGTGGTTCATCGGGATGATCGTCACGACGTTCCCGTGGCACTACGTCGGCATTCTCGGCAT
GCCGCGCCGGATGGCCTACTACGACTACAGCGATCCGGCGCTCGCGCCGCAGGCGGCGTGGGTGATCATGTCGGTCGTCG
GCGCGCTGATCCTCGTCGCGTCGGCCGTGCTGTTCTTCGTCGTGCTGCTACGCAGCCATTGCGGCGTGAAGGTCAAGCCG
GCCGAGTTCGCGTTCAGTTCGGCCGTCCATGAGCCGAAGACGCTGCCCGTCGCGCTCAACAGCTTCGGGCTGTGGATCGC
GCTGATGATCGGCCTCACGGTCGTCAACTACGGCTATCCGATCGCGCAATTGATGTCGCTCAAGCAACCGTCGGTGCCGG
CGATCTACATGGGGGCGCAGCGATGA

Upstream 100 bases:

>100_bases
GAATATTGCGGCACGGGCCACGAGGGGATGTGGGCGCACGTCAAGGTCATTGACCGTGCGGAATTCGACAAACTGGCGTC
CAGCGCGCGGAGACTGAGCT

Downstream 100 bases:

>100_bases
GCACGGAACGTCTGTTTTCGATTCGCAACCGCTGGTTGACGGTCAGCGTCGGGCTCACGCTGTTCGCGGTGGTCGCGTCG
GTGCTGATCGGCTTCGTCTG

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome c ba(3) subunit I; Cytochrome c oxidase polypeptide I; Cytochrome cba3 subunit 1 [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MLKNNRLVLAHFWLAFAVFGVALLLGAWQMLARSPLHPWLGNPELYYRSVTAHGSVMGYVFPTLIAMGFGYAISELALKM
PLVGRRWAWTGFWLIGLGSVVAMTPVSLGLSSVLYTFYPPMIGSPFYYLGVVLVVVGSWIWVALMSVNLYAWKKRNPGTP
IPLAMFANVAGAYLWGWTAVGAAIEILFQILPVAVGLKTTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGK
LYSDGMARISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAARLRGGKGAFGWLRA
LPWHEPMMLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRL
VKAQLWLWFIGMIVTTFPWHYVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLLRSHCGVKVKP
AEFAFSSAVHEPKTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMSLKQPSVPAIYMGAQR

Sequences:

>Translated_541_residues
MLKNNRLVLAHFWLAFAVFGVALLLGAWQMLARSPLHPWLGNPELYYRSVTAHGSVMGYVFPTLIAMGFGYAISELALKM
PLVGRRWAWTGFWLIGLGSVVAMTPVSLGLSSVLYTFYPPMIGSPFYYLGVVLVVVGSWIWVALMSVNLYAWKKRNPGTP
IPLAMFANVAGAYLWGWTAVGAAIEILFQILPVAVGLKTTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGK
LYSDGMARISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAARLRGGKGAFGWLRA
LPWHEPMMLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRL
VKAQLWLWFIGMIVTTFPWHYVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLLRSHCGVKVKP
AEFAFSSAVHEPKTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMSLKQPSVPAIYMGAQR
>Mature_541_residues
MLKNNRLVLAHFWLAFAVFGVALLLGAWQMLARSPLHPWLGNPELYYRSVTAHGSVMGYVFPTLIAMGFGYAISELALKM
PLVGRRWAWTGFWLIGLGSVVAMTPVSLGLSSVLYTFYPPMIGSPFYYLGVVLVVVGSWIWVALMSVNLYAWKKRNPGTP
IPLAMFANVAGAYLWGWTAVGAAIEILFQILPVAVGLKTTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGK
LYSDGMARISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAARLRGGKGAFGWLRA
LPWHEPMMLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRL
VKAQLWLWFIGMIVTTFPWHYVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLLRSHCGVKVKP
AEFAFSSAVHEPKTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMSLKQPSVPAIYMGAQR

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1786634, Length=485, Percent_Identity=24.3298969072165, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6226519, Length=261, Percent_Identity=29.1187739463602, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59467; Mature: 59467

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure
MLKNNRLVLAHFWLAFAVFGVALLLGAWQMLARSPLHPWLGNPELYYRSVTAHGSVMGYV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHH
FPTLIAMGFGYAISELALKMPLVGRRWAWTGFWLIGLGSVVAMTPVSLGLSSVLYTFYPP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MIGSPFYYLGVVLVVVGSWIWVALMSVNLYAWKKRNPGTPIPLAMFANVAGAYLWGWTAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
GAAIEILFQILPVAVGLKTTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LYSDGMARISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVEIAARLRGGKGAFGWLRALPWHEPMMLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNT
HHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCC
QWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRLVKAQLWLWFIGMIVTTFPWH
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLLRSHCGVKVKP
HHHHHCCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECH
AEFAFSSAVHEPKTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMSLKQPSVPAIYMGAQ
HHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEECCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7657607; 10338009; 10775261 [H]