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The map label for this gene is melR [C]

Identifier: 126452445

GI number: 126452445

Start: 1873815

End: 1874804

Strand: Direct

Name: melR [C]

Synonym: BURPS1106A_1919

Alternate gene names: 126452445

Gene position: 1873815-1874804 (Clockwise)

Preceding gene: 126452062

Following gene: 126453551

Centisome position: 46.98

GC content: 68.18

Gene sequence:

>990_bases
GTGCAGCCCGATCTCGAAGTCGTCGACGTGCGCCGCGGCGAGTCGTTCAAGGCGTGGGCGCATGGCTACCCGTACCGCAC
GGTGCGGTGGCACTTTCATCCGGAGTTCGAAGTGCATCTGATCGTCGAGACGACGGGGCAGATGTTCGTCGGCGATTATG
TCGGCGGCTTCGGCCCCGGCAATCTCGTGCTGATGGGACCGAACCTGCCGCACAACTGGGTGAGCGACGTGTCGGAAGGC
AGGACGATCGCCGAGCGCAATCTCGTCGTGCAGTTCGGCCAGGCGTTCGTGTCGCGCTGCGCGGACAGCTTCACCGAATG
GCGGCACGTCGAGGCGCTGCTCGCCGACGCGCGCCGCGGCGTGCAGTTCGGCCCGCGCACGAGCGAGGCGATCAAGCCGC
TCTTCGCCGAGCTGATTCACGCGCGGGGGTTGCGGCGCATCGTGCTGTTCCTGTCGATGCTGCAGATCCTCATCGACGCG
ACCGACCGCGAGCTGCTCGCGAGCCCCGCGTACGAAGCCGATGCGTCGAGCTTCGCGTCGACGCGCATCAACCACGTGCT
CGCGTACCTCGGCAAGAACCTCGCGAACGAGCTGCGCGAGACCGATCTCGCGCGGCTCGCCGGGCAGAGCGTGAGCGCGT
TCTCGCATGACTTCCGGCGGCACACCGGTTTGACGTTCGTCCAGTACGTGAACCGGATGCGGATCAATCTCGCGTGCCAA
CTGCTGATGGACGGCGACGCGAGCATCACCGACATCTGCTTCAGGAGCGGCTTCAACAACCTGTCGAACTTCAATCGCCA
GTTCCTCGCGGTGAAGGGCATGTCGCCGTCGCGCTTTCGCCGCTATCAGGCGCTGAACGACGCGAGTCGCGAGGCGTCCG
AGGCCGCCGCGCTGCGCGGCGCGGGCATCGCCGGCGCGCCGGCGATCGTGCCGGCCGCGCGGGCGCGCGGCGAGGCGCGT
GCGCCCGCCGAAGTCCTGCTGCCCGGCTGA

Upstream 100 bases:

>100_bases
CGTTCGCACTACGCAAGACGAACGACGGAGCGCCGCGGGCGCTCCGACACATCGGAGGAGCGGCGCGCGCGCCGTGGTCC
GAAGAAACAAGGAGGAGCGT

Downstream 100 bases:

>100_bases
GCCGGCCCGCGTTCCCGAGCAATCCAGCCCAACACGCGTCGCCCGGCGCGCCGCTCGCGCGGCGCGCGGGGTGCGCGCAT
CCCTAGAAAACGGAGACGAC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: AraC Family Transcriptional Regulator; Transcriptional Regulator; Helix-Turn-Helix Domain-Containing Protein; Helix-Turn-Helix- Domain Containing Protein AraC Type; Transcriptional Regulator Arac Family; Activator Protein MtlR; Transcriptional Regulator AraC Family Protein; AraC Family Regulatory Protein; Transcriptional Regulator Protein; Transcriptional Regulator MtlR; Activator Protein; Transcriptional Activator MltR; Transcriptional Regulator AraC/XylS Family; AraC Family Transcription Regulator; Helix-Turn-Helix AraC Type; AraC Family Transcription Regulator Protein; AraC Family Two Component Transcriptional Regulator; Two-Component Response Regulator; Transcriptional Activator; AraC/XylS Family Transcriptional Regulator; Transcriptional Regulatory Protein; Two Component Transcriptional Regulator AraC Family; Transcriptional Regulator Yfif; Helix-Turn-Helix Domain-Containing Protein AraC Type; Transcriptional Regulator Protein AraC Family; Helix-Turn-Helix Protein; ATPase Domain-Containing Protein; Xylan 1 4-Beta-Xylosidase

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQPDLEVVDVRRGESFKAWAHGYPYRTVRWHFHPEFEVHLIVETTGQMFVGDYVGGFGPGNLVLMGPNLPHNWVSDVSEG
RTIAERNLVVQFGQAFVSRCADSFTEWRHVEALLADARRGVQFGPRTSEAIKPLFAELIHARGLRRIVLFLSMLQILIDA
TDRELLASPAYEADASSFASTRINHVLAYLGKNLANELRETDLARLAGQSVSAFSHDFRRHTGLTFVQYVNRMRINLACQ
LLMDGDASITDICFRSGFNNLSNFNRQFLAVKGMSPSRFRRYQALNDASREASEAAALRGAGIAGAPAIVPAARARGEAR
APAEVLLPG

Sequences:

>Translated_329_residues
MQPDLEVVDVRRGESFKAWAHGYPYRTVRWHFHPEFEVHLIVETTGQMFVGDYVGGFGPGNLVLMGPNLPHNWVSDVSEG
RTIAERNLVVQFGQAFVSRCADSFTEWRHVEALLADARRGVQFGPRTSEAIKPLFAELIHARGLRRIVLFLSMLQILIDA
TDRELLASPAYEADASSFASTRINHVLAYLGKNLANELRETDLARLAGQSVSAFSHDFRRHTGLTFVQYVNRMRINLACQ
LLMDGDASITDICFRSGFNNLSNFNRQFLAVKGMSPSRFRRYQALNDASREASEAAALRGAGIAGAPAIVPAARARGEAR
APAEVLLPG
>Mature_329_residues
MQPDLEVVDVRRGESFKAWAHGYPYRTVRWHFHPEFEVHLIVETTGQMFVGDYVGGFGPGNLVLMGPNLPHNWVSDVSEG
RTIAERNLVVQFGQAFVSRCADSFTEWRHVEALLADARRGVQFGPRTSEAIKPLFAELIHARGLRRIVLFLSMLQILIDA
TDRELLASPAYEADASSFASTRINHVLAYLGKNLANELRETDLARLAGQSVSAFSHDFRRHTGLTFVQYVNRMRINLACQ
LLMDGDASITDICFRSGFNNLSNFNRQFLAVKGMSPSRFRRYQALNDASREASEAAALRGAGIAGAPAIVPAARARGEAR
APAEVLLPG

Specific function: Transcription Activator For The Expression Of The Melab Operon. Melr Binds At Two Sites Located Upstream Of The Melab Transcription Site. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790559, Length=268, Percent_Identity=22.7611940298507, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36472; Mature: 36472

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPDLEVVDVRRGESFKAWAHGYPYRTVRWHFHPEFEVHLIVETTGQMFVGDYVGGFGPG
CCCCCEEEEECCCCCCCHHHCCCCCCEEEEEECCCEEEEEEEECCCCEEEHHHCCCCCCC
NLVLMGPNLPHNWVSDVSEGRTIAERNLVVQFGQAFVSRCADSFTEWRHVEALLADARRG
CEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VQFGPRTSEAIKPLFAELIHARGLRRIVLFLSMLQILIDATDRELLASPAYEADASSFAS
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHH
TRINHVLAYLGKNLANELRETDLARLAGQSVSAFSHDFRRHTGLTFVQYVNRMRINLACQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEE
LLMDGDASITDICFRSGFNNLSNFNRQFLAVKGMSPSRFRRYQALNDASREASEAAALRG
EEECCCCHHHHHHHHHCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
AGIAGAPAIVPAARARGEARAPAEVLLPG
CCCCCCCHHHHHHHCCCCCCCCCEEECCC
>Mature Secondary Structure
MQPDLEVVDVRRGESFKAWAHGYPYRTVRWHFHPEFEVHLIVETTGQMFVGDYVGGFGPG
CCCCCEEEEECCCCCCCHHHCCCCCCEEEEEECCCEEEEEEEECCCCEEEHHHCCCCCCC
NLVLMGPNLPHNWVSDVSEGRTIAERNLVVQFGQAFVSRCADSFTEWRHVEALLADARRG
CEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VQFGPRTSEAIKPLFAELIHARGLRRIVLFLSMLQILIDATDRELLASPAYEADASSFAS
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHH
TRINHVLAYLGKNLANELRETDLARLAGQSVSAFSHDFRRHTGLTFVQYVNRMRINLACQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEE
LLMDGDASITDICFRSGFNNLSNFNRQFLAVKGMSPSRFRRYQALNDASREASEAAALRG
EEECCCCHHHHHHHHHCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
AGIAGAPAIVPAARARGEARAPAEVLLPG
CCCCCCCHHHHHHHCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA