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The map label for this gene is oprM [H]

Identifier: 126452102

GI number: 126452102

Start: 2149873

End: 2151777

Strand: Direct

Name: oprM [H]

Synonym: BURPS1106A_2164

Alternate gene names: 126452102

Gene position: 2149873-2151777 (Clockwise)

Preceding gene: 126452944

Following gene: 126455386

Centisome position: 53.9

GC content: 74.33

Gene sequence:

>1905_bases
ATGCGCGTTTCGATTCCTTCGCTCCCGAGTCTCGCGCCGCGCGCGCTCGCCGCGGCCGCCGCCATCGCGTTCGCGGGCGC
GCTCGCCGGCTGCTCGCTGTTCGCGCCGAGCGACGCGCCGCCCGCGATGCCGTCGCCCGCGCACTACGGCGCGACACCGC
TGCCCGAGCGCACGGCCGCCGCGCAGGGGCTCGCGCAACGCTTTGACGTGGGCGCGCAGCCGGTGCCCGACTGGTGGAAG
CGCTATCGCTCGCCCGCGCTCGACGCGCTCGTCGACGAAGGGCTGCGCAACAGCCCGACGCTCGCCGCCGCCGAAAAGAG
CCTGAGCGCCGCGCGCGAACAGTTGCGCGCGCAGATCGGCAGCTCGCTGCTGCCGACGATCGACGCCGGCGGCCAGGCGA
CGCGCGAGCGCGCGCTCGGCATGCCGGCGTTCGGCCCGCAGACGGTGCTCTACAACGTGTTCGCGGGCCAGTTGCAGGCG
AGCTACACGCTCGATCTGTTCGGCGCCGCGCGTTTCGCGAACCGCGCGCTGTCCAAGCGCGTCGACGTGAATGCGTACCA
GCTCGAATCCGCGCGGCGCGCGCTCGCCGCGAACATCGTGACGGCCGCCGTCACATCGGCCGCGCTCGCCGAGCAGGTCG
CGACGACCGAGCGGCTCGTCGCGCTCGCGCGCGAACAGGCGAGCGACGCGGCCGCGCGCCACCGGCTCGGCGCGGCGTCG
CGCACCGACATGCTGAACACGCGGCAAAGCGCGGCGGCGCTCGAGGCGAGCCTGCCCGCGCTGCGCCAGCAAGCGCAGAG
CGCGCGCCATGCGCTTGCCGTGCTGCTCGGCCGCACGCCGGATGCCGCGCCCGCGAATCTCGCGCTCGCCGATCTGCATC
TGCCGCAGGACGTGCCGGTCGTCGTGCCGTCGACGCTGCTGCAGGCGCGGCCCGACATCCGCGCGGCCGAGGCCGGCTTG
CAGGCTGCGGCGGCCGAGGTCGGCGTCGCGACCGCGCAGATGTTCCCGCAGTTGTCGCTGTCCGCGTCGATGGGCCATGC
GGGCTTCAAGTGGCCGGCGATGCTGTCGGGCGCGGGCGCGATCTGGAGCGTCGGTGCATCGCTCACGCAGCCGCTCTTTC
ACGGCGGCGCGCTGCTCGCGCAGCGCCGCGCGGCGCGCGCGAGCTACGACGCGGCCGTCGACCAGTACAAGCAGACGGTG
CTCGCCGCCTTCCAGGATGTGGCCGACAAGCTCGCCGCGCTCGAGAACGACGCGAGCGCACTCGACGCGTCGAACCGCTC
GGCCGTCGCCGCGCGCGGCGCGTTCGACGACACCGCGGCGCGCGTGCGGCTCGGCGCGCTGCCGCCGTCGGCCGCTCGCG
CGAGCGAGCAGCAGTACCGCAACGCGCGGCTCGACGAGATCCGCGCGACGGGCACGCGGCTTGTCGATACCGCGCGGCTC
TTTCAAGCGATGGGCACGCCGATCGACGGCGGGCCGGATGCGCGGCGTGTGGGCGGTATGAGCGGCTCGAATGATGTGAG
TGACGTAAGTGGATCGAGTGGTGTCGGCGGTGCGCACCGCGTGATCGACATACACGAAGCCGGTGCGGCGCAGCGTGCGG
ACGACGCGAAGCGGACCGGCGACGCGCGCATGCTTCGCGCGAACGGCAAGACCGAGGCGGCGCAAGCTTCCGTGACGGCG
AGCGCGGCCGCCGATGCGCCGGCCGCGCCCGCCCCGGCGGCTGCCGCCAGCGGCGCGAACGCGATACGGATACAGGCGCG
AACGCCACCGACCGCCGGCCTGTCCGCCGGCGCGATCGACGGCCCGATCGATGCGGCAAGCGCAACCGGCGCGACGAGCA
CGGCCCGCCCGGCAAACGGGCGCGACACGACGGTCGAATCGAACCCAACGCATTCGCCGAGCTAA

Upstream 100 bases:

>100_bases
TCACGCTCTTCTTCCTGCCGGCGCTCTATGCCGCGTGGTTCCGCGTGAAGCCGGACGAGCGCGATCCGGAGCCGCCCGCC
ACGCCTTCCGGAGCCTGACC

Downstream 100 bases:

>100_bases
CCGCGCGCGGCGCAAGCAGCGGCCGTCGCGGATTCGGCATGCGGCGGATCGAGCATGCAGCGCGTCGGGCGCCGTTGCGC
AGCCGACATCGCCGCGCAGG

Product: NodT family efflux transporter outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MRVSIPSLPSLAPRALAAAAAIAFAGALAGCSLFAPSDAPPAMPSPAHYGATPLPERTAAAQGLAQRFDVGAQPVPDWWK
RYRSPALDALVDEGLRNSPTLAAAEKSLSAAREQLRAQIGSSLLPTIDAGGQATRERALGMPAFGPQTVLYNVFAGQLQA
SYTLDLFGAARFANRALSKRVDVNAYQLESARRALAANIVTAAVTSAALAEQVATTERLVALAREQASDAAARHRLGAAS
RTDMLNTRQSAAALEASLPALRQQAQSARHALAVLLGRTPDAAPANLALADLHLPQDVPVVVPSTLLQARPDIRAAEAGL
QAAAAEVGVATAQMFPQLSLSASMGHAGFKWPAMLSGAGAIWSVGASLTQPLFHGGALLAQRRAARASYDAAVDQYKQTV
LAAFQDVADKLAALENDASALDASNRSAVAARGAFDDTAARVRLGALPPSAARASEQQYRNARLDEIRATGTRLVDTARL
FQAMGTPIDGGPDARRVGGMSGSNDVSDVSGSSGVGGAHRVIDIHEAGAAQRADDAKRTGDARMLRANGKTEAAQASVTA
SAAADAPAAPAPAAAASGANAIRIQARTPPTAGLSAGAIDGPIDAASATGATSTARPANGRDTTVESNPTHSPS

Sequences:

>Translated_634_residues
MRVSIPSLPSLAPRALAAAAAIAFAGALAGCSLFAPSDAPPAMPSPAHYGATPLPERTAAAQGLAQRFDVGAQPVPDWWK
RYRSPALDALVDEGLRNSPTLAAAEKSLSAAREQLRAQIGSSLLPTIDAGGQATRERALGMPAFGPQTVLYNVFAGQLQA
SYTLDLFGAARFANRALSKRVDVNAYQLESARRALAANIVTAAVTSAALAEQVATTERLVALAREQASDAAARHRLGAAS
RTDMLNTRQSAAALEASLPALRQQAQSARHALAVLLGRTPDAAPANLALADLHLPQDVPVVVPSTLLQARPDIRAAEAGL
QAAAAEVGVATAQMFPQLSLSASMGHAGFKWPAMLSGAGAIWSVGASLTQPLFHGGALLAQRRAARASYDAAVDQYKQTV
LAAFQDVADKLAALENDASALDASNRSAVAARGAFDDTAARVRLGALPPSAARASEQQYRNARLDEIRATGTRLVDTARL
FQAMGTPIDGGPDARRVGGMSGSNDVSDVSGSSGVGGAHRVIDIHEAGAAQRADDAKRTGDARMLRANGKTEAAQASVTA
SAAADAPAAPAPAAAASGANAIRIQARTPPTAGLSAGAIDGPIDAASATGATSTARPANGRDTTVESNPTHSPS
>Mature_634_residues
MRVSIPSLPSLAPRALAAAAAIAFAGALAGCSLFAPSDAPPAMPSPAHYGATPLPERTAAAQGLAQRFDVGAQPVPDWWK
RYRSPALDALVDEGLRNSPTLAAAEKSLSAAREQLRAQIGSSLLPTIDAGGQATRERALGMPAFGPQTVLYNVFAGQLQA
SYTLDLFGAARFANRALSKRVDVNAYQLESARRALAANIVTAAVTSAALAEQVATTERLVALAREQASDAAARHRLGAAS
RTDMLNTRQSAAALEASLPALRQQAQSARHALAVLLGRTPDAAPANLALADLHLPQDVPVVVPSTLLQARPDIRAAEAGL
QAAAAEVGVATAQMFPQLSLSASMGHAGFKWPAMLSGAGAIWSVGASLTQPLFHGGALLAQRRAARASYDAAVDQYKQTV
LAAFQDVADKLAALENDASALDASNRSAVAARGAFDDTAARVRLGALPPSAARASEQQYRNARLDEIRATGTRLVDTARL
FQAMGTPIDGGPDARRVGGMSGSNDVSDVSGSSGVGGAHRVIDIHEAGAAQRADDAKRTGDARMLRANGKTEAAQASVTA
SAAADAPAAPAPAAAASGANAIRIQARTPPTAGLSAGAIDGPIDAASATGATSTARPANGRDTTVESNPTHSPS

Specific function: The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP), showing that an energized inner membrane is required for efflux. It is thought that the mexB

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor. Note=Attached to the outer membrane by a lipid anchor and via the transmembrane beta-barrel. The membrane anchor is not necessary for antibiotic efflux. In one report (PubMed:10889211) the Cys-18- Gly mutant is reported

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=400, Percent_Identity=27.25, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI2367348, Length=409, Percent_Identity=24.9388753056235, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 64635; Mature: 64635

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSIPSLPSLAPRALAAAAAIAFAGALAGCSLFAPSDAPPAMPSPAHYGATPLPERTAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCHHHHH
AQGLAQRFDVGAQPVPDWWKRYRSPALDALVDEGLRNSPTLAAAEKSLSAAREQLRAQIG
HHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
SSLLPTIDAGGQATRERALGMPAFGPQTVLYNVFAGQLQASYTLDLFGAARFANRALSKR
CCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHH
VDVNAYQLESARRALAANIVTAAVTSAALAEQVATTERLVALAREQASDAAARHRLGAAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RTDMLNTRQSAAALEASLPALRQQAQSARHALAVLLGRTPDAAPANLALADLHLPQDVPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCE
VVPSTLLQARPDIRAAEAGLQAAAAEVGVATAQMFPQLSLSASMGHAGFKWPAMLSGAGA
ECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCH
IWSVGASLTQPLFHGGALLAQRRAARASYDAAVDQYKQTVLAAFQDVADKLAALENDASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LDASNRSAVAARGAFDDTAARVRLGALPPSAARASEQQYRNARLDEIRATGTRLVDTARL
HCCCCCCCEEECCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FQAMGTPIDGGPDARRVGGMSGSNDVSDVSGSSGVGGAHRVIDIHEAGAAQRADDAKRTG
HHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCHHCHHHHHCC
DARMLRANGKTEAAQASVTASAAADAPAAPAPAAAASGANAIRIQARTPPTAGLSAGAID
CCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCCCCCCCC
GPIDAASATGATSTARPANGRDTTVESNPTHSPS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVSIPSLPSLAPRALAAAAAIAFAGALAGCSLFAPSDAPPAMPSPAHYGATPLPERTAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCHHHHH
AQGLAQRFDVGAQPVPDWWKRYRSPALDALVDEGLRNSPTLAAAEKSLSAAREQLRAQIG
HHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
SSLLPTIDAGGQATRERALGMPAFGPQTVLYNVFAGQLQASYTLDLFGAARFANRALSKR
CCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHH
VDVNAYQLESARRALAANIVTAAVTSAALAEQVATTERLVALAREQASDAAARHRLGAAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RTDMLNTRQSAAALEASLPALRQQAQSARHALAVLLGRTPDAAPANLALADLHLPQDVPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCE
VVPSTLLQARPDIRAAEAGLQAAAAEVGVATAQMFPQLSLSASMGHAGFKWPAMLSGAGA
ECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCH
IWSVGASLTQPLFHGGALLAQRRAARASYDAAVDQYKQTVLAAFQDVADKLAALENDASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LDASNRSAVAARGAFDDTAARVRLGALPPSAARASEQQYRNARLDEIRATGTRLVDTARL
HCCCCCCCEEECCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FQAMGTPIDGGPDARRVGGMSGSNDVSDVSGSSGVGGAHRVIDIHEAGAAQRADDAKRTG
HHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCHHCHHHHHCC
DARMLRANGKTEAAQASVTASAAADAPAAPAPAAAASGANAIRIQARTPPTAGLSAGAID
CCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCCCCCCCC
GPIDAASATGATSTARPANGRDTTVESNPTHSPS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8226684; 10889211; 10984043; 7968531; 8540696; 9401051; 9603892; 10952562 [H]