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The map label for this gene is amt [H]

Identifier: 126452066

GI number: 126452066

Start: 453880

End: 455382

Strand: Direct

Name: amt [H]

Synonym: BURPS1106A_0488

Alternate gene names: 126452066

Gene position: 453880-455382 (Clockwise)

Preceding gene: 126451720

Following gene: 126453851

Centisome position: 11.38

GC content: 69.66

Gene sequence:

>1503_bases
ATGCGCAAAATCCTGATGTCCCTGTTGATGGCCGGCTCGCTGCTTGCGGGCGGCATCGGCGCCGCGATGGCCGACGACGC
GTCGTCGGCTCCCGCCGCCGCATCGGCCGCAACGGCTTCCGACACGTCGGCCGGCGCCGCCGCGTCCGCACCGGCCGCGT
CCGCCGCACCGGCCGCATCGGCGGCACCCGCCGCGTCGGCGCCCGCGGCAGCGTCCGCCGCCGCGCCGGCTTCGGCCGCC
GCCGCGCCCGCCGCGCCGACCGCGCCGTTCTCGGTCGATTCGTCGAAGATCAACTCGGGCGACACCGCGTGGATGCTCAC
GTCGACCGCGCTCGTGCTGTTCATGACGATCCCGGGCCTCGCGCTCTTCTACGGCGGCATGGTCCGCAAGAAGAACGTGC
TCGCGACCGTGATGCAGAGCTTCGCGATCACCGCGCTGATCACGGTCCTCTGGACGGTGGTCGGCTACAGCCTCGCGTTC
ACGCCGGGCAACGGCTTCATCGGCGGCTTCTCGCGCGTGTTCCTGTCCGGGATGAACTACATCCACGGCGACAAGGCGAC
GACGCTCACCGTCAGCCATCTCGCGTCGACGATCCCGGAATCGGTCTACTTCGTCTACCAGATGACGTTCGCGATCATCA
CGCCGGCGCTCATCTGCGGCGCGTTCGCCGACCGGATGAAATTCTCGGCGATGCTCGTCTTCATGACGCTGTGGTCGCTG
ATCGTCTACGTGCCGATCGCGCACATGGTCTGGGAGCCGACGGGCTGGCTGTCGGCGGACGGCGTGCTCGACTTCGCGGG
CGGCACGGTCGTGCACATCAACGCCGGCATCGCGGGCCTCGTGTCGTGCCTCATGCTCGGCAAGCGCGTCGGCTACGGCC
GCGAAGCGATGGCGCCGCACAACCTGGTGCTGACGCTGATCGGCGGCTCGATGCTGTGGGTGGGCTGGTTCGGCTTCAAC
GCGGGCTCCGCGGTGGCCGCGGACGGCCGCGCCGGCTTCGCGATGCTGACGACGCAAGTCGCCACCGCGTGCGCCGCGCT
CGGCTGGATGTTCGCCGAATGGATCGCCAAGGGTAAGCCTTCGGTGCTCGGCATCGTGTCGGGCGCGGTCGCGGGTCTCG
TCGCGATCACGCCGGCCGCCGGCTTCGTCGGCGTCGCGGGCGCGCTCGTGATCGGCATCGCGGCGGGCGTCGTCTGCTTC
TGGTCGGCGACGTGGCTCAAGCACAAGCTCGGCTACGACGATTCGCTCGACGCGTTCGGCGTGCACGGCGTGGGCGGCAT
TCTCGGCGCGCTGCTCACGGGCGTGTTCGCGGTCAAGGACATCGGCGGCGCGGACGGCAGCCTGCTGCTGCAGGCCAAGG
GCGTCGCGATCACGCTCGTCTACAGCGGCATCGTCAGCTTCGTGCTGCTGAAGGTGATCGACATCGTGATCGGCCTGCGC
GTGACCGAGGAAGAGGAGCGCGAAGGCCTCGACGTGATCCTGCACGGCGAGCACGTCGAATAA

Upstream 100 bases:

>100_bases
TCTTCGTCACGTCGATCGAGCAGGTGATTCGGATTCGTACCGGGGAGACGGGCGCTGACGCCCTGTAACAAGAGACACGA
GCGATAAGAGGAAAACCAAG

Downstream 100 bases:

>100_bases
TGGGATTCATCCCCGAGCCGGGAGCGGCGACGCGCACGCACGCTTTGCCGCCCGCAGAATGAGCGCAGCGATTTGGACCC
GCCTCCGAGGCGGGTTTTTT

Product: ammonium transporter

Products: NH3 [Cytoplasm] [C]

Alternate protein names: Ammonia transporter [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MRKILMSLLMAGSLLAGGIGAAMADDASSAPAAASAATASDTSAGAAASAPAASAAPAASAAPAASAPAAASAAAPASAA
AAPAAPTAPFSVDSSKINSGDTAWMLTSTALVLFMTIPGLALFYGGMVRKKNVLATVMQSFAITALITVLWTVVGYSLAF
TPGNGFIGGFSRVFLSGMNYIHGDKATTLTVSHLASTIPESVYFVYQMTFAIITPALICGAFADRMKFSAMLVFMTLWSL
IVYVPIAHMVWEPTGWLSADGVLDFAGGTVVHINAGIAGLVSCLMLGKRVGYGREAMAPHNLVLTLIGGSMLWVGWFGFN
AGSAVAADGRAGFAMLTTQVATACAALGWMFAEWIAKGKPSVLGIVSGAVAGLVAITPAAGFVGVAGALVIGIAAGVVCF
WSATWLKHKLGYDDSLDAFGVHGVGGILGALLTGVFAVKDIGGADGSLLLQAKGVAITLVYSGIVSFVLLKVIDIVIGLR
VTEEEEREGLDVILHGEHVE

Sequences:

>Translated_500_residues
MRKILMSLLMAGSLLAGGIGAAMADDASSAPAAASAATASDTSAGAAASAPAASAAPAASAAPAASAPAAASAAAPASAA
AAPAAPTAPFSVDSSKINSGDTAWMLTSTALVLFMTIPGLALFYGGMVRKKNVLATVMQSFAITALITVLWTVVGYSLAF
TPGNGFIGGFSRVFLSGMNYIHGDKATTLTVSHLASTIPESVYFVYQMTFAIITPALICGAFADRMKFSAMLVFMTLWSL
IVYVPIAHMVWEPTGWLSADGVLDFAGGTVVHINAGIAGLVSCLMLGKRVGYGREAMAPHNLVLTLIGGSMLWVGWFGFN
AGSAVAADGRAGFAMLTTQVATACAALGWMFAEWIAKGKPSVLGIVSGAVAGLVAITPAAGFVGVAGALVIGIAAGVVCF
WSATWLKHKLGYDDSLDAFGVHGVGGILGALLTGVFAVKDIGGADGSLLLQAKGVAITLVYSGIVSFVLLKVIDIVIGLR
VTEEEEREGLDVILHGEHVE
>Mature_500_residues
MRKILMSLLMAGSLLAGGIGAAMADDASSAPAAASAATASDTSAGAAASAPAASAAPAASAAPAASAPAAASAAAPASAA
AAPAAPTAPFSVDSSKINSGDTAWMLTSTALVLFMTIPGLALFYGGMVRKKNVLATVMQSFAITALITVLWTVVGYSLAF
TPGNGFIGGFSRVFLSGMNYIHGDKATTLTVSHLASTIPESVYFVYQMTFAIITPALICGAFADRMKFSAMLVFMTLWSL
IVYVPIAHMVWEPTGWLSADGVLDFAGGTVVHINAGIAGLVSCLMLGKRVGYGREAMAPHNLVLTLIGGSMLWVGWFGFN
AGSAVAADGRAGFAMLTTQVATACAALGWMFAEWIAKGKPSVLGIVSGAVAGLVAITPAAGFVGVAGALVIGIAAGVVCF
WSATWLKHKLGYDDSLDAFGVHGVGGILGALLTGVFAVKDIGGADGSLLLQAKGVAITLVYSGIVSFVLLKVIDIVIGLR
VTEEEEREGLDVILHGEHVE

Specific function: Involved in the uptake of ammonia [H]

COG id: COG0004

COG function: function code P; Ammonia permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ammonium transporter (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786656, Length=437, Percent_Identity=49.1990846681922, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17550182, Length=451, Percent_Identity=28.6031042128603, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17550180, Length=437, Percent_Identity=26.5446224256293, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32564042, Length=435, Percent_Identity=27.1264367816092, Blast_Score=115, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI133931100, Length=453, Percent_Identity=24.5033112582781, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324187, Length=430, Percent_Identity=36.046511627907, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6325396, Length=425, Percent_Identity=34.5882352941176, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6321559, Length=414, Percent_Identity=32.6086956521739, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI161078314, Length=418, Percent_Identity=28.2296650717703, Blast_Score=115, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001905
- InterPro:   IPR018047 [H]

Pfam domain/function: PF00909 Ammonium_transp [H]

EC number: NA

Molecular weight: Translated: 50599; Mature: 50599

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS01219 AMMONIUM_TRANSP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKILMSLLMAGSLLAGGIGAAMADDASSAPAAASAATASDTSAGAAASAPAASAAPAAS
CHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCC
AAPAASAPAAASAAAPASAAAAPAAPTAPFSVDSSKINSGDTAWMLTSTALVLFMTIPGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALFYGGMVRKKNVLATVMQSFAITALITVLWTVVGYSLAFTPGNGFIGGFSRVFLSGMNY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCC
IHGDKATTLTVSHLASTIPESVYFVYQMTFAIITPALICGAFADRMKFSAMLVFMTLWSL
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVYVPIAHMVWEPTGWLSADGVLDFAGGTVVHINAGIAGLVSCLMLGKRVGYGREAMAPH
HHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCC
NLVLTLIGGSMLWVGWFGFNAGSAVAADGRAGFAMLTTQVATACAALGWMFAEWIAKGKP
CEEEEEECCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVLGIVSGAVAGLVAITPAAGFVGVAGALVIGIAAGVVCFWSATWLKHKLGYDDSLDAFG
CEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VHGVGGILGALLTGVFAVKDIGGADGSLLLQAKGVAITLVYSGIVSFVLLKVIDIVIGLR
CCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCCC
VTEEEEREGLDVILHGEHVE
CCCHHHHCCCEEEEECCCCC
>Mature Secondary Structure
MRKILMSLLMAGSLLAGGIGAAMADDASSAPAAASAATASDTSAGAAASAPAASAAPAAS
CHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCC
AAPAASAPAAASAAAPASAAAAPAAPTAPFSVDSSKINSGDTAWMLTSTALVLFMTIPGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALFYGGMVRKKNVLATVMQSFAITALITVLWTVVGYSLAFTPGNGFIGGFSRVFLSGMNY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCC
IHGDKATTLTVSHLASTIPESVYFVYQMTFAIITPALICGAFADRMKFSAMLVFMTLWSL
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVYVPIAHMVWEPTGWLSADGVLDFAGGTVVHINAGIAGLVSCLMLGKRVGYGREAMAPH
HHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCC
NLVLTLIGGSMLWVGWFGFNAGSAVAADGRAGFAMLTTQVATACAALGWMFAEWIAKGKP
CEEEEEECCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVLGIVSGAVAGLVAITPAAGFVGVAGALVIGIAAGVVCFWSATWLKHKLGYDDSLDAFG
CEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VHGVGGILGALLTGVFAVKDIGGADGSLLLQAKGVAITLVYSGIVSFVLLKVIDIVIGLR
CCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCCC
VTEEEEREGLDVILHGEHVE
CCCHHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NH3 [Periplasm] [C]

Specific reaction: NH3 [Periplasm] = NH3 [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]