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The map label for this gene is hutI

Identifier: 126451924

GI number: 126451924

Start: 2686285

End: 2687508

Strand: Reverse

Name: hutI

Synonym: BURPS1106A_2719

Alternate gene names: 126451924

Gene position: 2687508-2686285 (Counterclockwise)

Preceding gene: 126454263

Following gene: 126454555

Centisome position: 67.38

GC content: 71.81

Gene sequence:

>1224_bases
ATGAAATCGATTCTCTGGCACAACCTGAAGCTGTGCGCGCACGGCGACCCGAACGACACGATCGCGGATGCGGCGATCGC
GGTGAACGGCGACGGCACGATCGCCTGGACCGGACGCGCGAGCGACGTGCCGGCCGGCTACGTGCACTGGCCGCGCGAGG
ACCTGCGCGGCGCATGGGTGACGCCCGGCCTCGTCGATTGCCACACGCACCTCGTCTACGGCGGCCAGCGCGCGGACGAG
TTCGCGCAGCGCCTGGCGGGGGCGAGCTACGAGGAGATCGCGCAGCGCGGCGGCGGCATCGTATCGACCGTGCGCGCGAC
GCGCGACGCGAGCGAGGCGGCGCTGTTCGAGCAGGCGTGCGCGCGGCTGCGGCCGCTCCTTGCCGAGGGCGTGACCGCGA
TCGAGATCAAGTCCGGCTACGGGCTCGAACTCGCGAGCGAGCGGCGGATGCTGCGCGTCGCGCGGCAGCTCGGCGAGCGC
TTTCCGGTGAGCGTCTATACGACGTTCCTCGGCGCGCACGCGCTGCCGCCCGAGTACGCGGGCCGCGCGGACGAATATAT
CGACGAGGTTTGCGAACGGATGCTGCCCGCGCTCGCCGACGAAGGGCTCGTCGACGCGGTCGACGTGTTTTGCGAGCGGA
TCGGCTTCACGCTCGCGCAGAGCGAGCGCGTGTTCGAAGCGGCGGCGCGGCGCGGGCTGCCCGTCAAGATGCACGCGGAG
CAGTTGTCGAACGGCGGCGGCTCCGCGCTCGCCGCGCGCTATCGCGCGCTGTCGGCCGACCACCTCGAATATCTGGACGC
GGCGGGCGTTGCCGCGATGCGTGCATCGGGCACGACGGCCGTGCTGCTGCCGGGCGCGTACTACTTCATCCGCGAGACGA
AGCTGCCGCCGATCGATCTGCTGCGCCGCCACGGCGTGCCGATCGCGCTCGCGACCGATCACAATCCGGGCACCTCGCCG
CTCACGTCGCTGCTGCTCACGATGAACATGGGCTGCACGGTGTTCAAGCTGACCGTGCAGGAGGCGCTCCTCGGCGTCAC
GCGCCACGCGGCGGCGGCGCTCGGCGCGAGCGACCGGCACGGCTCGCTCGCGCCCGGGCGGCAGGCGGATTTCGCGGTAT
GGTCGGTCTCGACGCTCGCCGAGCTCGCGTACTGGTTCGGCCGGCCGCTGTGCGAGCGGGTCGTGAAGGGCGGCGTGACG
GTGTTCACGCGCGATGCGCGCTGA

Upstream 100 bases:

>100_bases
CGTGCGCGCACGGCGAGTTCCGATGCGCGATTCGCGGCGAGGGCGTGCTCCTCGCCGTCGGCGTGACGCTTCTTCAAGAC
AACGCACAAGGCTCGATCGA

Downstream 100 bases:

>100_bases
CCGGACGATGAGCATGACGAAAATCGATTCGATGTTGTTTGCCGAGCAGGCGTATCTGCCCGGCGGCTGGCGGCGCGACG
TGCTGCTGCGCTGGAACGCG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWVTPGLVDCHTHLVYGGQRADE
FAQRLAGASYEEIAQRGGGIVSTVRATRDASEAALFEQACARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGER
FPVSVYTTFLGAHALPPEYAGRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDLLRRHGVPIALATDHNPGTSP
LTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRHGSLAPGRQADFAVWSVSTLAELAYWFGRPLCERVVKGGVT
VFTRDAR

Sequences:

>Translated_407_residues
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWVTPGLVDCHTHLVYGGQRADE
FAQRLAGASYEEIAQRGGGIVSTVRATRDASEAALFEQACARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGER
FPVSVYTTFLGAHALPPEYAGRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDLLRRHGVPIALATDHNPGTSP
LTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRHGSLAPGRQADFAVWSVSTLAELAYWFGRPLCERVVKGGVT
VFTRDAR
>Mature_407_residues
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWVTPGLVDCHTHLVYGGQRADE
FAQRLAGASYEEIAQRGGGIVSTVRATRDASEAALFEQACARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGER
FPVSVYTTFLGAHALPPEYAGRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDLLRRHGVPIALATDHNPGTSP
LTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRHGSLAPGRQADFAVWSVSTLAELAYWFGRPLCERVVKGGVT
VFTRDAR

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=389, Percent_Identity=35.9897172236504, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17555004, Length=427, Percent_Identity=33.2552693208431, Blast_Score=221, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_BURMA (Q62LJ2)

Other databases:

- EMBL:   CP000010
- RefSeq:   YP_102427.1
- HSSP:   Q8U8Z6
- ProteinModelPortal:   Q62LJ2
- SMR:   Q62LJ2
- GeneID:   3089468
- GenomeReviews:   CP000010_GR
- KEGG:   bma:BMA0649
- TIGR:   BMA0649
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   BMAL243160:BMA_0649-MONOMER
- BRENDA:   3.5.2.7
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 43777; Mature: 43777

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: BINDING 77-77 BINDING 90-90 BINDING 140-140 BINDING 173-173 BINDING 241-241

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWV
CCCCHHCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCEECCHHHCCCCCC
TPGLVDCHTHLVYGGQRADEFAQRLAGASYEEIAQRGGGIVSTVRATRDASEAALFEQAC
CCCHHHHHHHHEECCCHHHHHHHHHCCCCHHHHHHHCCCEEEHHHHHCCHHHHHHHHHHH
ARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGERFPVSVYTTFLGAHALPPEYA
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHC
GRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHH
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDL
HHCCCCCHHHHHHHHHHCHHHHHHHHHHCHHHHCCCCCEEEEECCEEEEEECCCCCHHHH
LRRHGVPIALATDHNPGTSPLTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRH
HHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCC
GSLAPGRQADFAVWSVSTLAELAYWFGRPLCERVVKGGVTVFTRDAR
CCCCCCCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWV
CCCCHHCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCEECCHHHCCCCCC
TPGLVDCHTHLVYGGQRADEFAQRLAGASYEEIAQRGGGIVSTVRATRDASEAALFEQAC
CCCHHHHHHHHEECCCHHHHHHHHHCCCCHHHHHHHCCCEEEHHHHHCCHHHHHHHHHHH
ARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGERFPVSVYTTFLGAHALPPEYA
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHC
GRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHH
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDL
HHCCCCCHHHHHHHHHHCHHHHHHHHHHCHHHHCCCCCEEEEECCEEEEEECCCCCHHHH
LRRHGVPIALATDHNPGTSPLTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRH
HHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCC
GSLAPGRQADFAVWSVSTLAELAYWFGRPLCERVVKGGVTVFTRDAR
CCCCCCCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA