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The map label for this gene is sucC [H]

Identifier: 126451915

GI number: 126451915

Start: 802004

End: 803170

Strand: Direct

Name: sucC [H]

Synonym: BURPS1106A_0817

Alternate gene names: 126451915

Gene position: 802004-803170 (Clockwise)

Preceding gene: 126454486

Following gene: 126452387

Centisome position: 20.11

GC content: 63.07

Gene sequence:

>1167_bases
ATGAAGATTCACGAGTACCAGGGTAAGGAAATCCTGCGGAAATTCGGAGTCGCGGTACCGCGCGGCAAGCCGGCGTTCTC
GGTGGACGAGGCCGTCAAGGTGGCGCAAGAGCTGGGCGGCCCGGTCTGGGTCGTCAAGGCCCAGATTCATGCGGGCGGCC
GCGGCAAGGGCGGCGGCGTGAAGGTCGCGAAGTCGCTCGAGCAAGTGCGCGAATACTCGAACCAGATCCTCGGCATGCAA
CTGAAGACGCACCAGACGGGCCCGGAAGGCCAGAAGGTCAACCGTCTGCTGATCGAAGAAGGCGCGGACATCAAGAAGGA
ACTGTATGTCGGCATCGTGATCGATCGCGTGTCGCAGAAGGTCGTCGTGATGGCGTCGAGCGAAGGCGGCATGGACATCG
AGGAAGTCGCGGAAAAGACGCCGGAAGCGATCCACAAGGTCGCCGTCGAGCCGTCGGTGGGCCTGCAGGACGCCGAAGCC
GACGATCTCGCGAAGAAGATCGGCGTGCCGGACGCATCGATCCCGCAAGCGCGCGAAATCCTGAAGGGCCTGTACAAGTC
GTTCTGGGAAACGGACGCGTCGCTCGCCGAAATCAACCCGCTCGTGCTGACGGGCGACGGCAAGGTGATCGCGCTCGACG
CGAAGTTCAACTTCGATTCGAACGCGCTGTTCCGCCATCCGGAAATCGTCGCGTACCGCGATCTGGACGAAGAAGATCCG
GCTGAAATCGAAGCGTCGAAGTTCGACCTCGCGTACATCTCGCTCGACGGCAACATCGGCTGCCTCGTGAACGGCGCGGG
CCTGGCGATGGCGACGATGGATACGATCAAGCTGTTCGGCGGCGAGCCGGCGAACTTCCTCGACGTCGGCGGCGGCGCGA
CGACCGAGAAGGTCACCGAAGCGTTCAAGCTGATGCTGAAGAACCCGGGCCTGAAGGCGATCCTCGTGAACATCTTCGGC
GGCATCATGCGCTGCGACGTGATCGCGGAAGGCGTGATCGCGGGCTCGAAGGCCGTGAACCTGAACGTGCCGCTCGTCGT
GCGCATGAAGGGCACGAACGAAGACCTCGGCAAGAAGATGCTTGCGGAATCCGGCCTGCCGATCATCTCGGCGGACAGCA
TGGAAGAAGCGGCGCAGAAGGTCGTCGCCGCGGCTGCGGGCAAGTAA

Upstream 100 bases:

>100_bases
GCGGACAGTGCGAAGGAATGAGGGCGAACGCTTGAATCGTCGGAAGAAGCGATCGTCAATCGACTTTTTTTAGCCAACTC
ACAGACTGAAGGAATCACGC

Downstream 100 bases:

>100_bases
GAGCGCCCGCGCCCGGCGCTTGGCGCCGGGCCCCCGAAGCGGGGCGGGAAGACTCGGGGCAGCCCGCGTTTTTCCGAGCG
CAACATTGAACACGCATGGC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYSNQILGMQ
LKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEA
DDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK

Sequences:

>Translated_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYSNQILGMQ
LKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEA
DDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK
>Mature_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYSNQILGMQ
LKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEA
DDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=48.3290488431877, Blast_Score=359, Evalue=2e-99,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=45.4308093994778, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=45.4038997214485, Blast_Score=307, Evalue=1e-83,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=53.3505154639175, Blast_Score=403, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=46.5648854961832, Blast_Score=352, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.6153846153846, Blast_Score=328, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=46.8193384223919, Blast_Score=354, Evalue=1e-98,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=45.4081632653061, Blast_Score=333, Evalue=9e-92,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=44.1326530612245, Blast_Score=321, Evalue=6e-88,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=44.1326530612245, Blast_Score=321, Evalue=6e-88,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=44.2748091603053, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=44.2748091603053, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI281363477, Length=411, Percent_Identity=27.007299270073, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363475, Length=411, Percent_Identity=27.007299270073, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363473, Length=411, Percent_Identity=27.007299270073, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41286; Mature: 41286

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50975 ATP_GRASP ; PS00063 ALDOKETO_REDUCTASE_3 ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLEQVREYSNQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQK
HHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHEEEEEEECCCCE
VVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEADDLAKKIGVPDASIPQAREI
EEEEECCCCCCCHHHHHHHCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHHCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LAESGLPIISADSMEEAAQKVVAAAAGK
HHHCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLEQVREYSNQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQK
HHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHEEEEEEECCCCE
VVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEADDLAKKIGVPDASIPQAREI
EEEEECCCCCCCHHHHHHHCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHHCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LAESGLPIISADSMEEAAQKVVAAAAGK
HHHCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA