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The map label for this gene is dctB [H]

Identifier: 126451792

GI number: 126451792

Start: 443351

End: 445384

Strand: Direct

Name: dctB [H]

Synonym: BURPS1106A_0477

Alternate gene names: 126451792

Gene position: 443351-445384 (Clockwise)

Preceding gene: 126452996

Following gene: 126454917

Centisome position: 11.12

GC content: 71.39

Gene sequence:

>2034_bases
ATGAACGCGGAAACGGCGGGGCGCGCAGCGGCGCCCGCGCCGGGCGGGGCCGGGCCGGACGCGACGAGACGCGCCTGGCC
CGGCCCCGCGGCCTTTTCGGGCGGCGGCTATGCCACAATAGACGATCCTTACAGTCCGGAAGCCGTCACCGTGAAGCGCC
GCCTGCTCGTCGTTCTCGCGCTCGCCGCGATGCTCGCGGCCGCGTGCGCGCTTACCTGGACGCTCACGTGGCAAAGCGGC
ATCGCCGATCTGCGCGACAGCGCGGCCGCGCGCGTCGACCGCACGACGAACGCGCTGAAGAGCACGCTCGACCGTTACGA
ATCGCTGCCTTACCTGCTGGGCGGCCACCCGTTCGTGCAGGATGTCCTCGCCGATCCGGCCAACCGTCGCCAGGTGAACC
GCGCGAACGCCTATCTCGAGGACATGAACCGCCACGCGCACGCGACGGCGACCTACGTGATCACCGCGAGCGGGCTGTGC
GTCGCCGCGAGCAACTGGCGCGGCCCGGACAGCTTCACCGGCATCGGCTATCAGTTTCGGCCGTACTTCATCGACGCGGT
GAAGGGCGGCACCGGCCGCTTCTTCGGGATCGGCACGATCTCGCGCGATCCCGGCTACTACATCTCGCAGCCGGTGCGGC
GCGACGGCAAGATCATCGGCGTCGCCGTCGTCAAGCTCAATCTCGAATGGTTCCAGGGCGCGGACGCGTCGGAGCCGCTC
GTCGTCGCCGACGACCACGGCGTGATCTTCCTGTCGTCGGTGCCGCAGTGGAAGTACCACACGCTCAAGCCGCTGCCGGG
GCCGATCGCGACGTCGATCCACGAGACGCGCCAGTACGCGCACTATCCGGTGACGCCGCTGCCGCTGCGCGTCGAGCGCG
TGCTCGGGCCCGACGCGCAGATCGTGCGGATGGGCGCCGCGCGCCGCGCGCCGCGCTATCTCGCGACGCGCCGCCTGCTC
GGCGAGCCCGACTGGCAGCTCGTCACGCTCGCGCCGATCGAGCCGGTCGACGCCGACGCGCGCAACGCGACGATCGTCAC
CGCGTTCGGCTTCGTGTCGCTCAGCCTGCTCGCGTTCTACTGGCGCACGCGCCGCGCGCGCGTGAAGGAGATGCTGCGCA
GCCGCGTGCTGCTGCAAAGCGCGTATGCGGAGCTGAACCGGCGTGTCGAGGAGCGCACGGCGGATCTGTCGCAGGCGAAC
GCGCGGCTCAAGAAGGAAGTCGGCGAGCGCATCCGCGCGGAGCAGGAACTGCGCGCCGCGCACGACGAGCTCGTCCAGGC
GAGCAAGCTCGCCGCGCTCGGCCAGATGGCGGCCGGCATCACGCACGAGCTGAACCAGCCGCTCGCCGCGCTGCGCAGCT
TCTCCGACAACACCCGCGTGCTGCTCGACCGCGGCGAGCAGGCGGCCGCGCGCGAGAACCTGGAGGCGATCGCCGCGCTC
ACCGAGCGGATGGGCAAGATCACGAATCAGCTCAAGCTGTTCGTCGGGCGTGCGAAGCCGCGCAACGAGCGGGCGCACGT
CGCGCGCGCGCTGCGCAACGTGCTCGCGCTGCTCAAGGAGCGGATGAAGGACGTCGAGCTGGTGATCACGCTGCGCGACG
AGACGCGCGATCCCGCCGCCGCCGCGCGCTTCGATCCGTCACGGGACGAGCCGGCGCTCATTGCGCGCTGCGAGGATCTG
CGGCTCGAGCAGGTACTCATCAACCTGCTCGGCAACGCGCTCGACGCGGTCGCGGCGGTCGCTGCGCCGCGCATCGACGT
GGCGATCGATGCGACCGCCGCGACGCTGGCGATCACCGTGCGCGACAATGGGCCGGGCATCGCGCCGGAATCGCTCGCGC
GGCTGTTCGAGCCGTTCTTCACGACGAAGGAAATGGGGCGCGGCCTCGGGCTCGGCCTCGCGATCTCGTCGTCGATCGCG
CGCGACGCGGGCGGCTCGCTCACCGCGCGCAACGCGCCGGCGGGCGGCGCGGAGTTCGTCTTGACGCTGCGCCGCGCGCG
CACGCATCATCCGGACACTTCCGCCGCGAGTTGA

Upstream 100 bases:

>100_bases
TCGTGTCCGCGTGGGAGAAGGAGCTCGACCGCGCGAAGCTGCGCGCGGCGCTGTCGGGCAACGGCGAGGCAGCCGCGGGC
GAAGCCGCGCGGGTCTGACG

Downstream 100 bases:

>100_bases
GCGCGCACCTTTCGCGCGGCCCGCGTCAGCATCATGGGGTGACAGAAGATGGCGAACCGCCTGCAAGTGATCTACATCGA
AGACGACGAGCTCGTGCGCC

Product: C4-dicarboxylate transport sensor histidine kinase DctB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MNAETAGRAAAPAPGGAGPDATRRAWPGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLALAAMLAAACALTWTLTWQSG
IADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQDVLADPANRRQVNRANAYLEDMNRHAHATATYVITASGLC
VAASNWRGPDSFTGIGYQFRPYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
VVADDHGVIFLSSVPQWKYHTLKPLPGPIATSIHETRQYAHYPVTPLPLRVERVLGPDAQIVRMGAARRAPRYLATRRLL
GEPDWQLVTLAPIEPVDADARNATIVTAFGFVSLSLLAFYWRTRRARVKEMLRSRVLLQSAYAELNRRVEERTADLSQAN
ARLKKEVGERIRAEQELRAAHDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
TERMGKITNQLKLFVGRAKPRNERAHVARALRNVLALLKERMKDVELVITLRDETRDPAAAARFDPSRDEPALIARCEDL
RLEQVLINLLGNALDAVAAVAAPRIDVAIDATAATLAITVRDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIA
RDAGGSLTARNAPAGGAEFVLTLRRARTHHPDTSAAS

Sequences:

>Translated_677_residues
MNAETAGRAAAPAPGGAGPDATRRAWPGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLALAAMLAAACALTWTLTWQSG
IADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQDVLADPANRRQVNRANAYLEDMNRHAHATATYVITASGLC
VAASNWRGPDSFTGIGYQFRPYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
VVADDHGVIFLSSVPQWKYHTLKPLPGPIATSIHETRQYAHYPVTPLPLRVERVLGPDAQIVRMGAARRAPRYLATRRLL
GEPDWQLVTLAPIEPVDADARNATIVTAFGFVSLSLLAFYWRTRRARVKEMLRSRVLLQSAYAELNRRVEERTADLSQAN
ARLKKEVGERIRAEQELRAAHDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
TERMGKITNQLKLFVGRAKPRNERAHVARALRNVLALLKERMKDVELVITLRDETRDPAAAARFDPSRDEPALIARCEDL
RLEQVLINLLGNALDAVAAVAAPRIDVAIDATAATLAITVRDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIA
RDAGGSLTARNAPAGGAEFVLTLRRARTHHPDTSAAS
>Mature_677_residues
MNAETAGRAAAPAPGGAGPDATRRAWPGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLALAAMLAAACALTWTLTWQSG
IADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQDVLADPANRRQVNRANAYLEDMNRHAHATATYVITASGLC
VAASNWRGPDSFTGIGYQFRPYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
VVADDHGVIFLSSVPQWKYHTLKPLPGPIATSIHETRQYAHYPVTPLPLRVERVLGPDAQIVRMGAARRAPRYLATRRLL
GEPDWQLVTLAPIEPVDADARNATIVTAFGFVSLSLLAFYWRTRRARVKEMLRSRVLLQSAYAELNRRVEERTADLSQAN
ARLKKEVGERIRAEQELRAAHDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
TERMGKITNQLKLFVGRAKPRNERAHVARALRNVLALLKERMKDVELVITLRDETRDPAAAARFDPSRDEPALIARCEDL
RLEQVLINLLGNALDAVAAVAAPRIDVAIDATAATLAITVRDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIA
RDAGGSLTARNAPAGGAEFVLTLRRARTHHPDTSAAS

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=284, Percent_Identity=29.5774647887324, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=28.3464566929134, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786912, Length=291, Percent_Identity=30.2405498281787, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787894, Length=330, Percent_Identity=28.4848484848485, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1789149, Length=286, Percent_Identity=24.8251748251748, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=290, Percent_Identity=28.9655172413793, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI145693157, Length=278, Percent_Identity=25.8992805755396, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=245, Percent_Identity=30.2040816326531, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73441; Mature: 73441

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50109 HIS_KIN ; PS00210 HEMOCYANIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAETAGRAAAPAPGGAGPDATRRAWPGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
LAAMLAAACALTWTLTWQSGIADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQ
HHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHH
DVLADPANRRQVNRANAYLEDMNRHAHATATYVITASGLCVAASNWRGPDSFTGIGYQFR
HHHCCCHHHHHHHHHHHHHHHHCCHHCCEEEEEEEECCEEEEECCCCCCCCCCCCCEEEC
PYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
CEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCCE
VVADDHGVIFLSSVPQWKYHTLKPLPGPIATSIHETRQYAHYPVTPLPLRVERVLGPDAQ
EEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHH
IVRMGAARRAPRYLATRRLLGEPDWQLVTLAPIEPVDADARNATIVTAFGFVSLSLLAFY
HHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
WRTRRARVKEMLRSRVLLQSAYAELNRRVEERTADLSQANARLKKEVGERIRAEQELRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
TERMGKITNQLKLFVGRAKPRNERAHVARALRNVLALLKERMKDVELVITLRDETRDPAA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCH
AARFDPSRDEPALIARCEDLRLEQVLINLLGNALDAVAAVAAPRIDVAIDATAATLAITV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEEE
RDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIARDAGGSLTARNAPAGGAEFV
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHH
LTLRRARTHHPDTSAAS
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNAETAGRAAAPAPGGAGPDATRRAWPGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
LAAMLAAACALTWTLTWQSGIADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQ
HHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHH
DVLADPANRRQVNRANAYLEDMNRHAHATATYVITASGLCVAASNWRGPDSFTGIGYQFR
HHHCCCHHHHHHHHHHHHHHHHCCHHCCEEEEEEEECCEEEEECCCCCCCCCCCCCEEEC
PYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
CEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCCE
VVADDHGVIFLSSVPQWKYHTLKPLPGPIATSIHETRQYAHYPVTPLPLRVERVLGPDAQ
EEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHH
IVRMGAARRAPRYLATRRLLGEPDWQLVTLAPIEPVDADARNATIVTAFGFVSLSLLAFY
HHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
WRTRRARVKEMLRSRVLLQSAYAELNRRVEERTADLSQANARLKKEVGERIRAEQELRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
TERMGKITNQLKLFVGRAKPRNERAHVARALRNVLALLKERMKDVELVITLRDETRDPAA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCH
AARFDPSRDEPALIARCEDLRLEQVLINLLGNALDAVAAVAAPRIDVAIDATAATLAITV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEEE
RDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIARDAGGSLTARNAPAGGAEFV
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHH
LTLRRARTHHPDTSAAS
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]