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The map label for this gene is oprM [H]

Identifier: 126451768

GI number: 126451768

Start: 1592735

End: 1594444

Strand: Reverse

Name: oprM [H]

Synonym: BURPS1106A_1641

Alternate gene names: 126451768

Gene position: 1594444-1592735 (Counterclockwise)

Preceding gene: 126452845

Following gene: 126454379

Centisome position: 39.98

GC content: 74.68

Gene sequence:

>1710_bases
ATGCGGCGCGCACTCACGCGATGGCGGCTGTCGTTCGCGCTCGGCGCGCTCGCCGCGCTCGCGAGCGCGTGCACGGTCGG
GCCGGACTTTCATCCTCCGCGCGCCGACGTGCCCGCGCAATGGCATGACGTGACGGCTACTTCGACTTCATCGGCTTCAT
CGGCTTCATCGGCCGCATCGCCCCCGGCGGCCGGCTCGGGCGCGCCGAACGCCGGCGCGCCGCCCCGTTCGCTGCCGACG
GTCGAGGCCGACCCGGACCCGCGCTGGTGGCGCACGTTCGGCGATCCGGTGCTCGATCGCCTTGTCGAGCGCGCCGCGCA
GGACAATCTCGACGTGCAGGCCGCGGTGCTGCGCATCGCCGAGGCGCGCGCGCAGGTGCGCGCGGCGGCCGCGCAGGGGC
TGCCCGACGTGCGCGCGAGCGCGAGCTACCAGCGCGAACAGCTCGGCCTGAAGGGCTTTCTCGAGGACGGCGGCGTAGAC
GCGCAGCTCGAGCGGCTGGGCGCGCCGGGCTCGCCGCTCGAGCGCATCGCGCCCGGCGCGGGCGCGGCGCTGCGCCGCGG
CGCCGAGCACACGCTCGACCAGCTCACGTCGCCCGTGAACCTGTGGCAGGCCGGCTTCGACGCATCGTGGGAGCTCGACC
TGTTCGGCCGCGTGCGGCGCTCGGTCGAGGCGGCGGGCGCGCAGACGCAAGCCGCGATTGAAGGCCGCAACGACGCGCTG
CTGTCGCTCGAAGCGGAAGTCGCGCAGACCTATCTGCAACTGCGCGGCGCGCAGGCGCTGCGCACGCTCGCCGTCGCGCT
CGCCGACGAGCAGCGCGACGTCGTCGCGCTCACGCGCGATCAGGCGCGCAAGGGGCTATCGAGCGAGCTCGACGTGCAAA
GCGCCGACGCGCGGCTCGCGCAACTGCGCGCGCAGTTGCCGCAATTCGACCAGCAGATCGCGCTGCTGCGCAACGGCCTG
TCCTACCTGCTCGGCGACGCGCCGGGCGCGCTCGACGACGCGCTGCGCGAGCCGCGCGCGCTGCCGGAGCTTCCGCCGAC
GGTGCCGATCGGGCTGCCGTCGACGCTCGCGCGCCGCCGCCCGGACATCCGTCGCGCGGAAGCGCAACTGCACGCGGCGA
CCGCCGGCGTCGGCGTGGCTGTCGCGCAGTTCTACCCGGACGTCTCGCTGACGGGCCAGGTCGGCACGCGCGCGACGCAC
GCGCGCGAGCTCGCGCACTGGTCGCATCTGTTCTATGCGTTCGGGCCGAGCGTGTCGCTGCCGATCTTCGAGGGCGGCGC
GCTCGTCGCGAACCTGCGCCTGTCGCAGGCGCAACAGGCGCAGGCGGCGCTCGGCTATCGGCGCGCCGTGCTGCTCGCGC
TGCGCGACGTCGACAACGCGCTCGCCGCGTACCGGACCGACCAGACGCGCCGTGACGCGCTGCGTGACGCGGCGGCCGCC
GAGCGCACGACGTTCGAGCTCGCGCGCGACAGCTATCGCCACGGGCTCGTGTCGTTCATCGACGTGCTCGACGCCGAGCG
CGAGCTGTCGCAGGCGCGCCAGCAATACGTGCAGGGCAGCCTGCAACTGACGACCGATCTCGTCTCGCTGTACAAGGCGC
TCGGCGGCGGCTGGCAGCCCGTGCCGGCCGCGCAAACGCCCGCGCCCGCCGCCCTCGACGCCCCGACGCAAGACACGCCG
CTCGGCGCAACGGCGCCTGCGCGACGATGA

Upstream 100 bases:

>100_bases
GACGTGTTCGCGATGCTCGCGATCTTCTGCTTCGTGTGCACGCCCCTCACGCTGCTTTTCTCGCCCGTGAAGGCGGCGGG
CGGCCCGGGAGGACACTGAT

Downstream 100 bases:

>100_bases
ACAGCCGCTTGAACGGAAACCGCGTGCGGCCGTCGTCTCCGCGCGGATAGAGCGCATGCAGGCGCGGCACGTATCGATCG
AGACAGCGGTCGCGCTCGTC

Product: NodT family efflux transporter outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MRRALTRWRLSFALGALAALASACTVGPDFHPPRADVPAQWHDVTATSTSSASSASSAASPPAAGSGAPNAGAPPRSLPT
VEADPDPRWWRTFGDPVLDRLVERAAQDNLDVQAAVLRIAEARAQVRAAAAQGLPDVRASASYQREQLGLKGFLEDGGVD
AQLERLGAPGSPLERIAPGAGAALRRGAEHTLDQLTSPVNLWQAGFDASWELDLFGRVRRSVEAAGAQTQAAIEGRNDAL
LSLEAEVAQTYLQLRGAQALRTLAVALADEQRDVVALTRDQARKGLSSELDVQSADARLAQLRAQLPQFDQQIALLRNGL
SYLLGDAPGALDDALREPRALPELPPTVPIGLPSTLARRRPDIRRAEAQLHAATAGVGVAVAQFYPDVSLTGQVGTRATH
ARELAHWSHLFYAFGPSVSLPIFEGGALVANLRLSQAQQAQAALGYRRAVLLALRDVDNALAAYRTDQTRRDALRDAAAA
ERTTFELARDSYRHGLVSFIDVLDAERELSQARQQYVQGSLQLTTDLVSLYKALGGGWQPVPAAQTPAPAALDAPTQDTP
LGATAPARR

Sequences:

>Translated_569_residues
MRRALTRWRLSFALGALAALASACTVGPDFHPPRADVPAQWHDVTATSTSSASSASSAASPPAAGSGAPNAGAPPRSLPT
VEADPDPRWWRTFGDPVLDRLVERAAQDNLDVQAAVLRIAEARAQVRAAAAQGLPDVRASASYQREQLGLKGFLEDGGVD
AQLERLGAPGSPLERIAPGAGAALRRGAEHTLDQLTSPVNLWQAGFDASWELDLFGRVRRSVEAAGAQTQAAIEGRNDAL
LSLEAEVAQTYLQLRGAQALRTLAVALADEQRDVVALTRDQARKGLSSELDVQSADARLAQLRAQLPQFDQQIALLRNGL
SYLLGDAPGALDDALREPRALPELPPTVPIGLPSTLARRRPDIRRAEAQLHAATAGVGVAVAQFYPDVSLTGQVGTRATH
ARELAHWSHLFYAFGPSVSLPIFEGGALVANLRLSQAQQAQAALGYRRAVLLALRDVDNALAAYRTDQTRRDALRDAAAA
ERTTFELARDSYRHGLVSFIDVLDAERELSQARQQYVQGSLQLTTDLVSLYKALGGGWQPVPAAQTPAPAALDAPTQDTP
LGATAPARR
>Mature_569_residues
MRRALTRWRLSFALGALAALASACTVGPDFHPPRADVPAQWHDVTATSTSSASSASSAASPPAAGSGAPNAGAPPRSLPT
VEADPDPRWWRTFGDPVLDRLVERAAQDNLDVQAAVLRIAEARAQVRAAAAQGLPDVRASASYQREQLGLKGFLEDGGVD
AQLERLGAPGSPLERIAPGAGAALRRGAEHTLDQLTSPVNLWQAGFDASWELDLFGRVRRSVEAAGAQTQAAIEGRNDAL
LSLEAEVAQTYLQLRGAQALRTLAVALADEQRDVVALTRDQARKGLSSELDVQSADARLAQLRAQLPQFDQQIALLRNGL
SYLLGDAPGALDDALREPRALPELPPTVPIGLPSTLARRRPDIRRAEAQLHAATAGVGVAVAQFYPDVSLTGQVGTRATH
ARELAHWSHLFYAFGPSVSLPIFEGGALVANLRLSQAQQAQAALGYRRAVLLALRDVDNALAAYRTDQTRRDALRDAAAA
ERTTFELARDSYRHGLVSFIDVLDAERELSQARQQYVQGSLQLTTDLVSLYKALGGGWQPVPAAQTPAPAALDAPTQDTP
LGATAPARR

Specific function: The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP), showing that an energized inner membrane is required for efflux. It is thought that the mexB

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor. Note=Attached to the outer membrane by a lipid anchor and via the transmembrane beta-barrel. The membrane anchor is not necessary for antibiotic efflux. In one report (PubMed:10889211) the Cys-18- Gly mutant is reported

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=523, Percent_Identity=27.151051625239, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI2367348, Length=465, Percent_Identity=26.8817204301075, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 60537; Mature: 60537

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRALTRWRLSFALGALAALASACTVGPDFHPPRADVPAQWHDVTATSTSSASSASSAAS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPAAGSGAPNAGAPPRSLPTVEADPDPRWWRTFGDPVLDRLVERAAQDNLDVQAAVLRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHH
EARAQVRAAAAQGLPDVRASASYQREQLGLKGFLEDGGVDAQLERLGAPGSPLERIAPGA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCCCCCHHHHHCCCCCCCHHHHCCCC
GAALRRGAEHTLDQLTSPVNLWQAGFDASWELDLFGRVRRSVEAAGAQTQAAIEGRNDAL
CHHHHCCHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCE
LSLEAEVAQTYLQLRGAQALRTLAVALADEQRDVVALTRDQARKGLSSELDVQSADARLA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCCCCCCCCCHHHHHHHH
QLRAQLPQFDQQIALLRNGLSYLLGDAPGALDDALREPRALPELPPTVPIGLPSTLARRR
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCC
PDIRRAEAQLHAATAGVGVAVAQFYPDVSLTGQVGTRATHARELAHWSHLFYAFGPSVSL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
PIFEGGALVANLRLSQAQQAQAALGYRRAVLLALRDVDNALAAYRTDQTRRDALRDAAAA
EEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ERTTFELARDSYRHGLVSFIDVLDAERELSQARQQYVQGSLQLTTDLVSLYKALGGGWQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
VPAAQTPAPAALDAPTQDTPLGATAPARR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRALTRWRLSFALGALAALASACTVGPDFHPPRADVPAQWHDVTATSTSSASSASSAAS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPAAGSGAPNAGAPPRSLPTVEADPDPRWWRTFGDPVLDRLVERAAQDNLDVQAAVLRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHH
EARAQVRAAAAQGLPDVRASASYQREQLGLKGFLEDGGVDAQLERLGAPGSPLERIAPGA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCCCCCHHHHHCCCCCCCHHHHCCCC
GAALRRGAEHTLDQLTSPVNLWQAGFDASWELDLFGRVRRSVEAAGAQTQAAIEGRNDAL
CHHHHCCHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCE
LSLEAEVAQTYLQLRGAQALRTLAVALADEQRDVVALTRDQARKGLSSELDVQSADARLA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCCCCCCCCCHHHHHHHH
QLRAQLPQFDQQIALLRNGLSYLLGDAPGALDDALREPRALPELPPTVPIGLPSTLARRR
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCC
PDIRRAEAQLHAATAGVGVAVAQFYPDVSLTGQVGTRATHARELAHWSHLFYAFGPSVSL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
PIFEGGALVANLRLSQAQQAQAALGYRRAVLLALRDVDNALAAYRTDQTRRDALRDAAAA
EEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ERTTFELARDSYRHGLVSFIDVLDAERELSQARQQYVQGSLQLTTDLVSLYKALGGGWQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
VPAAQTPAPAALDAPTQDTPLGATAPARR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8226684; 10889211; 10984043; 7968531; 8540696; 9401051; 9603892; 10952562 [H]