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The map label for this gene is nadA [H]

Identifier: 126451762

GI number: 126451762

Start: 961169

End: 962305

Strand: Direct

Name: nadA [H]

Synonym: BURPS1106A_0978

Alternate gene names: 126451762

Gene position: 961169-962305 (Clockwise)

Preceding gene: 126452903

Following gene: 126454043

Centisome position: 24.1

GC content: 67.55

Gene sequence:

>1137_bases
ATGCAATCGGCGATCAAATCCGTCGAGTACGACCGCCCGCTCGCAGCAGGGGCGGCCTGCGGCGTCGGCGAGGCATGGGC
CAAGGTGCCCGACGCGCTCGCCCCCGACGAGCGCGACGCGCTGAAGGCGCGAATCAAGGCGTTGCTCGTGCGTGAAAAGG
CGGTGCTGGTCGCGCATTATTACGTCGACGCGGATCTGCAGGCGCTCGCGGACGAGACGGGCGGGTGCGTCGCCGATTCG
CTGGAGATGGCCCGCTTCGGCCGCGATCACGACGCGCACACGCTCGTGGTCGCCGGCGTGCGCTTCATGGGCGAGACGGC
GAAGATCCTGAGCCCGGGCAAGCGCGTGCTGATGCCCGATCTCGACGCGACGTGCTCGCTCGATCTCGGCTGCCTGGTCG
ACGAGTTCTCGCAATTCTGCGACGCGCATCCGGAGCGCACGGTCGTCGTCTATGCGAACACGAGCGCCGCGGTGAAGGCA
CGCGCCGACTGGATGGTCACGTCGTCGATCGGCCTCGAGATCGTCGCCGATCTGCACGCGCGCGGCGAGAAGATCATCTG
GGCGCCGGACCGGCACCTCGGCGGCTACATCCAGAAGAAGACCGGTGCGGACATGTTGATGTGGCAGGGCTCGTGCCTCG
TGCACGACGAATTCAAGGGCATCGAGCTGGACCTGCTGCGCCGCGAATATCCGGACGCGAAGATCCTCGTGCATCCCGAA
TCGCCCGAGGGCGTCGTCGCGCTCGCGGACGTCGTCGGCTCGACGACGCAACTGATCGATGCGGCCGTGAAGCTCGACGC
GCAACGCTTCATCGTCGCGACCGATCTCGGCATCCTGCACAAGATGCGGCTCGCGGCGCCCGGCAAGACCTTCATCGAGG
CGCCGACGGCCGGCAACAGCGCGACTTGCAAGAGCTGCGCGCACTGCCCATGGATGGCGATGAACGCGCTGTCGAACCTG
GCCGACGTGCTCGAGCGCGGCCATAACGAGATCTTCGTCGAGGCGGCGATCGCGCAGCGCGCACGCATGCCGATCGACCG
AATGCTCGATTTCGCCGCGCGTCACAAGCAGCGCGTGCAGGCGAGCGGCGATCTGCAGCGCGACCAGGCGCTGTTCGCAA
ACGTGGGGGCGGCATGA

Upstream 100 bases:

>100_bases
TTGGGCCGGCCGTTCTTGCGATGCCGGCCGATCGGCAGGGCTGGACTTTGCATGGAACCGGATTCGGCGCTACGGCGCCG
CCGGGCGATAGGAGATGAGG

Downstream 100 bases:

>100_bases
CCATCGACGCGGTATCGCCGCTCTTTGCCGACATCTCGCGCGAATACGGCGCCGCGTTCGACGCGGCGATCGCGCGCAAC
GTCGCCGATGCGCTCGCGGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MQSAIKSVEYDRPLAAGAACGVGEAWAKVPDALAPDERDALKARIKALLVREKAVLVAHYYVDADLQALADETGGCVADS
LEMARFGRDHDAHTLVVAGVRFMGETAKILSPGKRVLMPDLDATCSLDLGCLVDEFSQFCDAHPERTVVVYANTSAAVKA
RADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRREYPDAKILVHPE
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNALSNL
ADVLERGHNEIFVEAAIAQRARMPIDRMLDFAARHKQRVQASGDLQRDQALFANVGAA

Sequences:

>Translated_378_residues
MQSAIKSVEYDRPLAAGAACGVGEAWAKVPDALAPDERDALKARIKALLVREKAVLVAHYYVDADLQALADETGGCVADS
LEMARFGRDHDAHTLVVAGVRFMGETAKILSPGKRVLMPDLDATCSLDLGCLVDEFSQFCDAHPERTVVVYANTSAAVKA
RADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRREYPDAKILVHPE
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNALSNL
ADVLERGHNEIFVEAAIAQRARMPIDRMLDFAARHKQRVQASGDLQRDQALFANVGAA
>Mature_378_residues
MQSAIKSVEYDRPLAAGAACGVGEAWAKVPDALAPDERDALKARIKALLVREKAVLVAHYYVDADLQALADETGGCVADS
LEMARFGRDHDAHTLVVAGVRFMGETAKILSPGKRVLMPDLDATCSLDLGCLVDEFSQFCDAHPERTVVVYANTSAAVKA
RADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRREYPDAKILVHPE
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNALSNL
ADVLERGHNEIFVEAAIAQRARMPIDRMLDFAARHKQRVQASGDLQRDQALFANVGAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=326, Percent_Identity=63.8036809815951, Blast_Score=436, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40863; Mature: 40863

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAIKSVEYDRPLAAGAACGVGEAWAKVPDALAPDERDALKARIKALLVREKAVLVAHY
CCHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEE
YVDADLQALADETGGCVADSLEMARFGRDHDAHTLVVAGVRFMGETAKILSPGKRVLMPD
EECCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHHCCCCEEECCC
LDATCSLDLGCLVDEFSQFCDAHPERTVVVYANTSAAVKARADWMVTSSIGLEIVADLHA
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEECCCCHHHEEHHHC
RGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRREYPDAKILVHPE
CCCEEEECCCCCCCCEEECCCCCCEEEECCCEEEECCCCCCCHHHHHHCCCCCEEEECCC
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNS
CCCCEEEEHHHHCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCEEECCCCCCC
ATCKSCAHCPWMAMNALSNLADVLERGHNEIFVEAAIAQRARMPIDRMLDFAARHKQRVQ
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHH
ASGDLQRDQALFANVGAA
HCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MQSAIKSVEYDRPLAAGAACGVGEAWAKVPDALAPDERDALKARIKALLVREKAVLVAHY
CCHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEE
YVDADLQALADETGGCVADSLEMARFGRDHDAHTLVVAGVRFMGETAKILSPGKRVLMPD
EECCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHHCCCCEEECCC
LDATCSLDLGCLVDEFSQFCDAHPERTVVVYANTSAAVKARADWMVTSSIGLEIVADLHA
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEECCCCHHHEEHHHC
RGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRREYPDAKILVHPE
CCCEEEECCCCCCCCEEECCCCCCEEEECCCEEEECCCCCCCHHHHHHCCCCCEEEECCC
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNS
CCCCEEEEHHHHCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCEEECCCCCCC
ATCKSCAHCPWMAMNALSNLADVLERGHNEIFVEAAIAQRARMPIDRMLDFAARHKQRVQ
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHH
ASGDLQRDQALFANVGAA
HCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA