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The map label for this gene is lgrB [H]

Identifier: 126443154

GI number: 126443154

Start: 1612919

End: 1617622

Strand: Reverse

Name: lgrB [H]

Synonym: BURPS668_A1674

Alternate gene names: 126443154

Gene position: 1617622-1612919 (Counterclockwise)

Preceding gene: 126442826

Following gene: 126444869

Centisome position: 51.72

GC content: 75.09

Gene sequence:

>4704_bases
ATGACGACAAGCGCTTCTTCGCCGAACCTTGCTTTCGCCGCCGGCGAGCGGCCCGCCGCGCCGGCGATCGAAGCGGTGCT
GCCGCTCACGCCGATGCAGCACGGCATGCTGTTCCACAGCCTGCTCGATCCGGCGTCGGCCGTGTTCTTCCAGCAACTCG
TCGCCGAATTCGACGGCGCGCTCGACGCGCAGGCGTTCGCCGCCGCATGGGCGGACCTCGTCGACCGGCATCAGAGCCTG
CGCACCGCGTTTCTTTGGGAGCGGCGCGACGAGCCGCGGCAGGTCGTGCTGCGCCGCGCGCGCGTGCCGCTCGAATGGCT
CGACTGGTCGGATCTCGGCGGGGACGACGCGCGCGACGCATTCGACGCGAGGCTCGACGCGCACCTGCGCGCGGACCGCG
AGCGGCGTTTCGATCCGGCCAGGGCGCCGCTGCTGCGCGTCGCGATGGTACGCCGCGCGGCCGCGCGCCACCTGATGATC
GTCAGCCATCACCATCTGATTCTCGACGGATGGTCGACGGGCGTCCTGCTCGGCGAACTACAGGCGCTGCATGCGGCGCG
CCTGCGGCGGCGCGCGGCCGCGCTGCCGCCCGCGCCGCGCTACGCGGCGTTCGTCGAGCACCTCGGGCGCGCCGGGCGGC
CGTGCGACGACGCGTTCTGGCGCGCGATGCTCGCCGGGTTCGCGCAGCCGACGCCGCTCGTCGGCGACATCCGGCGGGAC
GCGGCGACGAGCGGCGACTACGTGCCGTGCGATCTGCGGCTCGAGTCGGCCGCGCGCCGCGCGCTGGAGGACGCCGCGCG
GCGTCATCGCGTATCGGCGGCCGTTGCCGTGTTCGCCGCGTGGGCGTGGCTGCTCGCGCGGCGGGCGGACGTGCCGGAGG
TCGTCTACGGCGTGACGGTGGCCGGCCGGCCGGCGGAATTGCCCAGCGCGCAGCGGCTCGTCGGGCTTTGCATCAACACG
ATCCCGCTGCGCGCGAGCGCGCCGACGCGCGGCGACGTCGGCGGCTGGCTGCGCGATGTGCAGGAGCGGCTCGCGCGCGC
GCAGCCGCACGAGCATGCGTCGCTGTCGGCGATCCAGCGCGCGTCGGCGGTGCCGCCGGGCGTGCCGTTGTTCGACAGCC
TCGTCGTCTACGAGAACTACCCGATCGCGCCGCCGCCCGCCGACGCGCCGCTGCGGCTCGTGCACGCGCGCGTCGAGGAG
CGCGCGAACTATGCGCTGACGCTGATCGCGGAGCCGCAGGCCGACGGGCTCGCGTTGCGGCTGATCGTCGATCGCACGCG
CATCGCGCCGCACGAGGGGCGGCGCATGCTCGAGCAGTTGCGCGTCGTGCTCGACGGCATCGCGCGCGCCGGCGAGCACG
CGGATCTCGCCGGCCTCGCGCTGCTCACGCCCGACGCGCAGCGCCGCATGCTGCAGGACTGGAACGCGACGCACGCGCCG
TACGATCGCACGGCCACGCTGCATGGGCTGTTCGCGCGCCGCGCGGCGCAGGCGCCGGACGCGCCCGCGCTGATCGACGG
CGCGGGCACGCTCGGCTACGGCGAGCTGGACCGGCTGAGCCGCGCGGTCGCCGCCGCGCTCGACGCGGCGGGCGTGCCCG
CGGGTGCGCCCGTCGCGGTGCGCATGCTGCGCGACCGGCACCTCGTCGCGGCGCTGCTCGGCATCCTGCGCTCGGGCCGC
GCGTACGTGCCGCTGCCGCGCGATCTGCCGCCCGCCCGGGTCGGCGACATCGTCGACGCCATGTCGATCGGCTGCGTCGT
CACGTCGGCGGCGCTGCGCGACGAGACGGCGGCGCATCTGGGCGGCCGCCCGGCGGCGCGGCTCGTCGCGGAGGAGATCG
TCCGCGGCGCGCCCGCGCGCGAGTCGGGGCGCGGCGGCGCCGACGATCTCGCGTACGTGATCTTCACGTCCGGGTCGACC
GGCAAGCCCAAGGGCGTGATGGTGCGGCACCGGCCGGCGGTCAACCTGATCGACTGGGTGAATCGCCGCTTCGGCGTCGG
GCCGTCGGACCGGCTGCTGTTCGTGACCTCGCCCGCGTTCGACCTGTCCGTCTACGACATCTTCGGCGTACTCGCGGCGG
GCGGCTCGATCCGCATCGCGAGCGACGACGAGGTGGCGGACCCCGAGCGGCTCGCCCGCATGCTCGCCGACGAGCCCGTC
ACCTTCTGGGACAGCGCGCCGGCCGCGCTCTGGCAGCTCCATCCGCTGCTGCCGGAGCGCGTCGAGGGCAGCCGCCTGCG
GCTCGTGTTCTGCAGCGGCGACTGGATTCCGCTGTCGCTGCCCGAGCGGATGCGCGGCTGCTTTCCGGGGGCGACGGTGG
TCGCGCTCGGCGGCGCGACCGAGGCGACGATCTGGTCGAACTACCACGTCGTCGAGCGCGTCGAGCCCGGCTGGCGCAGC
ATCCCGTACGGCCGGCCGATCCAGAACGCGCGCTACTACATCCTCGACCGGGCGCTGCGCCCGGTGCCGCCCGGCATCCC
GGGCGACCTGTACATCGGCGGCGAATGCCTGTGCGACGGCTACGCCGGGCAGCCGGCGCTGACGGCCGAGCGCTTCGTCC
CCGATCCGCACGCCGAGCGCCCGGGCGCGCGCATGTACCGCACCGGCGACCGCGCGCGTTTCTGGGACGACGCGACGATC
GAGTTCCTCGGCCGCGACGATCATCAGGTGAAGATTCGCGGCTTCCGTGTCGAGCTGGGCGAGGTCGAGGCGGCGCTCGC
CCGGCATCCGGACGTGCGCGACGCGGTGGCCGTCGTGCGCACGGGCGGCGAGGGCGGGCCGGCGGACGGCCGCGACGACC
GGGCGCTCGTCGCGTACGCGGTGCCGAAGCCGGGCGGCCGCGCGAGCGCCGCCGATCTGCTCGCGCATCTGCGCGGCCTG
TTGCCGCCGCCGATGGTGCCGGCGCATCTGGTGATGCTGGACGCGCTGCCCGTGAGCGCGAACGGCAAGGTCGACCGGCG
CGCGCTGCCCGCGCCGCTCGCCGATCGCGCGCAGGCGGGCGGCGCGACGCATCTGGTCGAGGAACTGGTGGCCGCGATCT
GGGCGGACGTGCTCGGCCTCGCGTCGGTGCCGGTCGATCAGGACTTCTTCGCGCTGGGCGGCCATTCGCTGCGCGCGACG
TCGGCGATCGCACGGCTGCGCGTCGCGCTGCGCAAGGAGCTGCCGCTCGCGCTGCTGTACCGGCACCCGAGCGTGCGCGA
GCTGAGCGCGGCGATCGTTGCCGGCGGCGCGTGCGCACCCGATGCGGGCGGCGCGCAGGACGGCGCGCCGCCGCGGCTGT
CGCGCGACGGCCCGCTGCCGCTGTCGCCCGCGCAGGAGCGGCTGTGGTTCCTGCATCGCCTGGAGCCGGACAGCCCGTTC
TACACGATCGTGCTCGCGGCCTGGCTCGACGGGCGCGTCGAGCGCGCGGCGCTCGAGCGGGCCGTGGCCGTGGTGGTCGA
GCGCCACGAGATCCTGCGCAGCCATATCGTCGACATCGACGGCCGGCCCGCGCAGACACCCGCTCGCGCCGACCTGCCGC
TGCCGATCCGGGTGGTGGACCTGACGGGCGCCGCCGACCCGCAGGCCGAAGCGCTCGCGCTCGCGCGCGCCGAGGCGCTG
CGGCCGTTCGATCTGGCGCGCGCGCTGCCGTTCCGGGTGCTGCTCGCGCCGACGCGCGCGGATCGCGCGCTCGCGCTGAT
CCTGATGGATCACGCGGCGGCCGACGGCTGGTCGATCGGCATCTTCGCGCAGGAACTGCTCGGCGCGTACGACGCGCTCG
TCGACGGCGCGGCGCCGGCGCTGCTGCCGCTCGACGCGCAATACGCGGATCTGAGCGCGTGGCAGGCGGCGCGCCTCGGG
CGCGGCGAGCTCGAACGGCAGCTCGACTACTGGCGCGCGACGCTCGCGGGCCTGCCGGCGCTGAACCTGCCGACCGACCG
GCCGCGCGCGCCGACGCCACGCTTCGCGGGCGCGGTGGTGCGCTTCCACGTGCCGGCGGCGAGCGCACGCGCGCTCGCGG
CGCTCGCGCGCCGCGAGAGCTGCACGCTGTTCATGGTCGGGCTCGCCGCGTTCGCGACGGTGCTGCGCCACCGCAGCGGG
CAGGACGATCTGGCGATCGGCACGGATCTCGCGGGGCGCACCCACCCCGCGGCGGAGCGGCTGATCGGCTTCTTCGTGAA
CCAGCTGGTGCTGCGCATCGACCTGAGCGGCTGCGACAGCTTCCGCGATGCGCTGCGCGCGGTGCGCGAGCGCGCGCTCG
ACGGGTTTTTCCATCAGGACGTGCCGTTCGACACGTTGGTGCGCGCGCTGAATCCGCCGCGCGAGCCCGGGCGGATGCCG
CTGTTCCAGGTGAAGTTCGTGTTGCAGAACACGCCGTTCGTCACGCTGTCGAGCCGCCATCTGCGCGTCGAGCCGCTCGA
CATCGACACGGGGACCGCGAAGTACGACTTGCTCGCGACCCTGGCCGAGCGGCCCGACGGACTCGCGGGCACGCTCGAAT
ACTCGACCGATCTGTTCGACGCGGCGACGGCGGAGGGCATCGCCGCCGATCTGCAGGCGGTGCTCGATCTCGTCGCGCAG
AACGCCGCGGTGGGCGTGGCCGACATCGCGCGGCTGCTCGATGCGGGGCACGCGCAGCGTGCGGAGCTCGGCCGTCAGAG
CCTGCGTCGCGCGGGGCTCGAACGGTTGCGCCGGCTCGCGAGCGCGCAAGGAGGGACGCGATGA

Upstream 100 bases:

>100_bases
CGCGGATTCGCGACGCGCTGCACGCGGCGGACCGCATCGAGGCGATCGGCGAGCGGGTTTTCTTCACGTTGCTCGGACAC
TGATGGAGGCGAGCCGACCG

Downstream 100 bases:

>100_bases
ACGACGTCTTCGGCGAACGCGCGAGCGATGTCGCGAGCGGCATGAAGGGCGGCACGAAGGACGGCATCCGGACGGGCGAT
GTCAAGAAGGGCGATATCAA

Product: linear gramicidin synthetase subunit B

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1567; Mature: 1566

Protein sequence:

>1567_residues
MTTSASSPNLAFAAGERPAAPAIEAVLPLTPMQHGMLFHSLLDPASAVFFQQLVAEFDGALDAQAFAAAWADLVDRHQSL
RTAFLWERRDEPRQVVLRRARVPLEWLDWSDLGGDDARDAFDARLDAHLRADRERRFDPARAPLLRVAMVRRAAARHLMI
VSHHHLILDGWSTGVLLGELQALHAARLRRRAAALPPAPRYAAFVEHLGRAGRPCDDAFWRAMLAGFAQPTPLVGDIRRD
AATSGDYVPCDLRLESAARRALEDAARRHRVSAAVAVFAAWAWLLARRADVPEVVYGVTVAGRPAELPSAQRLVGLCINT
IPLRASAPTRGDVGGWLRDVQERLARAQPHEHASLSAIQRASAVPPGVPLFDSLVVYENYPIAPPPADAPLRLVHARVEE
RANYALTLIAEPQADGLALRLIVDRTRIAPHEGRRMLEQLRVVLDGIARAGEHADLAGLALLTPDAQRRMLQDWNATHAP
YDRTATLHGLFARRAAQAPDAPALIDGAGTLGYGELDRLSRAVAAALDAAGVPAGAPVAVRMLRDRHLVAALLGILRSGR
AYVPLPRDLPPARVGDIVDAMSIGCVVTSAALRDETAAHLGGRPAARLVAEEIVRGAPARESGRGGADDLAYVIFTSGST
GKPKGVMVRHRPAVNLIDWVNRRFGVGPSDRLLFVTSPAFDLSVYDIFGVLAAGGSIRIASDDEVADPERLARMLADEPV
TFWDSAPAALWQLHPLLPERVEGSRLRLVFCSGDWIPLSLPERMRGCFPGATVVALGGATEATIWSNYHVVERVEPGWRS
IPYGRPIQNARYYILDRALRPVPPGIPGDLYIGGECLCDGYAGQPALTAERFVPDPHAERPGARMYRTGDRARFWDDATI
EFLGRDDHQVKIRGFRVELGEVEAALARHPDVRDAVAVVRTGGEGGPADGRDDRALVAYAVPKPGGRASAADLLAHLRGL
LPPPMVPAHLVMLDALPVSANGKVDRRALPAPLADRAQAGGATHLVEELVAAIWADVLGLASVPVDQDFFALGGHSLRAT
SAIARLRVALRKELPLALLYRHPSVRELSAAIVAGGACAPDAGGAQDGAPPRLSRDGPLPLSPAQERLWFLHRLEPDSPF
YTIVLAAWLDGRVERAALERAVAVVVERHEILRSHIVDIDGRPAQTPARADLPLPIRVVDLTGAADPQAEALALARAEAL
RPFDLARALPFRVLLAPTRADRALALILMDHAAADGWSIGIFAQELLGAYDALVDGAAPALLPLDAQYADLSAWQAARLG
RGELERQLDYWRATLAGLPALNLPTDRPRAPTPRFAGAVVRFHVPAASARALAALARRESCTLFMVGLAAFATVLRHRSG
QDDLAIGTDLAGRTHPAAERLIGFFVNQLVLRIDLSGCDSFRDALRAVRERALDGFFHQDVPFDTLVRALNPPREPGRMP
LFQVKFVLQNTPFVTLSSRHLRVEPLDIDTGTAKYDLLATLAERPDGLAGTLEYSTDLFDAATAEGIAADLQAVLDLVAQ
NAAVGVADIARLLDAGHAQRAELGRQSLRRAGLERLRRLASAQGGTR

Sequences:

>Translated_1567_residues
MTTSASSPNLAFAAGERPAAPAIEAVLPLTPMQHGMLFHSLLDPASAVFFQQLVAEFDGALDAQAFAAAWADLVDRHQSL
RTAFLWERRDEPRQVVLRRARVPLEWLDWSDLGGDDARDAFDARLDAHLRADRERRFDPARAPLLRVAMVRRAAARHLMI
VSHHHLILDGWSTGVLLGELQALHAARLRRRAAALPPAPRYAAFVEHLGRAGRPCDDAFWRAMLAGFAQPTPLVGDIRRD
AATSGDYVPCDLRLESAARRALEDAARRHRVSAAVAVFAAWAWLLARRADVPEVVYGVTVAGRPAELPSAQRLVGLCINT
IPLRASAPTRGDVGGWLRDVQERLARAQPHEHASLSAIQRASAVPPGVPLFDSLVVYENYPIAPPPADAPLRLVHARVEE
RANYALTLIAEPQADGLALRLIVDRTRIAPHEGRRMLEQLRVVLDGIARAGEHADLAGLALLTPDAQRRMLQDWNATHAP
YDRTATLHGLFARRAAQAPDAPALIDGAGTLGYGELDRLSRAVAAALDAAGVPAGAPVAVRMLRDRHLVAALLGILRSGR
AYVPLPRDLPPARVGDIVDAMSIGCVVTSAALRDETAAHLGGRPAARLVAEEIVRGAPARESGRGGADDLAYVIFTSGST
GKPKGVMVRHRPAVNLIDWVNRRFGVGPSDRLLFVTSPAFDLSVYDIFGVLAAGGSIRIASDDEVADPERLARMLADEPV
TFWDSAPAALWQLHPLLPERVEGSRLRLVFCSGDWIPLSLPERMRGCFPGATVVALGGATEATIWSNYHVVERVEPGWRS
IPYGRPIQNARYYILDRALRPVPPGIPGDLYIGGECLCDGYAGQPALTAERFVPDPHAERPGARMYRTGDRARFWDDATI
EFLGRDDHQVKIRGFRVELGEVEAALARHPDVRDAVAVVRTGGEGGPADGRDDRALVAYAVPKPGGRASAADLLAHLRGL
LPPPMVPAHLVMLDALPVSANGKVDRRALPAPLADRAQAGGATHLVEELVAAIWADVLGLASVPVDQDFFALGGHSLRAT
SAIARLRVALRKELPLALLYRHPSVRELSAAIVAGGACAPDAGGAQDGAPPRLSRDGPLPLSPAQERLWFLHRLEPDSPF
YTIVLAAWLDGRVERAALERAVAVVVERHEILRSHIVDIDGRPAQTPARADLPLPIRVVDLTGAADPQAEALALARAEAL
RPFDLARALPFRVLLAPTRADRALALILMDHAAADGWSIGIFAQELLGAYDALVDGAAPALLPLDAQYADLSAWQAARLG
RGELERQLDYWRATLAGLPALNLPTDRPRAPTPRFAGAVVRFHVPAASARALAALARRESCTLFMVGLAAFATVLRHRSG
QDDLAIGTDLAGRTHPAAERLIGFFVNQLVLRIDLSGCDSFRDALRAVRERALDGFFHQDVPFDTLVRALNPPREPGRMP
LFQVKFVLQNTPFVTLSSRHLRVEPLDIDTGTAKYDLLATLAERPDGLAGTLEYSTDLFDAATAEGIAADLQAVLDLVAQ
NAAVGVADIARLLDAGHAQRAELGRQSLRRAGLERLRRLASAQGGTR
>Mature_1566_residues
TTSASSPNLAFAAGERPAAPAIEAVLPLTPMQHGMLFHSLLDPASAVFFQQLVAEFDGALDAQAFAAAWADLVDRHQSLR
TAFLWERRDEPRQVVLRRARVPLEWLDWSDLGGDDARDAFDARLDAHLRADRERRFDPARAPLLRVAMVRRAAARHLMIV
SHHHLILDGWSTGVLLGELQALHAARLRRRAAALPPAPRYAAFVEHLGRAGRPCDDAFWRAMLAGFAQPTPLVGDIRRDA
ATSGDYVPCDLRLESAARRALEDAARRHRVSAAVAVFAAWAWLLARRADVPEVVYGVTVAGRPAELPSAQRLVGLCINTI
PLRASAPTRGDVGGWLRDVQERLARAQPHEHASLSAIQRASAVPPGVPLFDSLVVYENYPIAPPPADAPLRLVHARVEER
ANYALTLIAEPQADGLALRLIVDRTRIAPHEGRRMLEQLRVVLDGIARAGEHADLAGLALLTPDAQRRMLQDWNATHAPY
DRTATLHGLFARRAAQAPDAPALIDGAGTLGYGELDRLSRAVAAALDAAGVPAGAPVAVRMLRDRHLVAALLGILRSGRA
YVPLPRDLPPARVGDIVDAMSIGCVVTSAALRDETAAHLGGRPAARLVAEEIVRGAPARESGRGGADDLAYVIFTSGSTG
KPKGVMVRHRPAVNLIDWVNRRFGVGPSDRLLFVTSPAFDLSVYDIFGVLAAGGSIRIASDDEVADPERLARMLADEPVT
FWDSAPAALWQLHPLLPERVEGSRLRLVFCSGDWIPLSLPERMRGCFPGATVVALGGATEATIWSNYHVVERVEPGWRSI
PYGRPIQNARYYILDRALRPVPPGIPGDLYIGGECLCDGYAGQPALTAERFVPDPHAERPGARMYRTGDRARFWDDATIE
FLGRDDHQVKIRGFRVELGEVEAALARHPDVRDAVAVVRTGGEGGPADGRDDRALVAYAVPKPGGRASAADLLAHLRGLL
PPPMVPAHLVMLDALPVSANGKVDRRALPAPLADRAQAGGATHLVEELVAAIWADVLGLASVPVDQDFFALGGHSLRATS
AIARLRVALRKELPLALLYRHPSVRELSAAIVAGGACAPDAGGAQDGAPPRLSRDGPLPLSPAQERLWFLHRLEPDSPFY
TIVLAAWLDGRVERAALERAVAVVVERHEILRSHIVDIDGRPAQTPARADLPLPIRVVDLTGAADPQAEALALARAEALR
PFDLARALPFRVLLAPTRADRALALILMDHAAADGWSIGIFAQELLGAYDALVDGAAPALLPLDAQYADLSAWQAARLGR
GELERQLDYWRATLAGLPALNLPTDRPRAPTPRFAGAVVRFHVPAASARALAALARRESCTLFMVGLAAFATVLRHRSGQ
DDLAIGTDLAGRTHPAAERLIGFFVNQLVLRIDLSGCDSFRDALRAVRERALDGFFHQDVPFDTLVRALNPPREPGRMPL
FQVKFVLQNTPFVTLSSRHLRVEPLDIDTGTAKYDLLATLAERPDGLAGTLEYSTDLFDAATAEGIAADLQAVLDLVAQN
AAVGVADIARLLDAGHAQRAELGRQSLRRAGLERLRRLASAQGGTR

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=448, Percent_Identity=26.3392857142857, Blast_Score=94, Evalue=2e-18,
Organism=Homo sapiens, GI38505220, Length=531, Percent_Identity=23.1638418079096, Blast_Score=79, Evalue=5e-14,
Organism=Escherichia coli, GI1786801, Length=970, Percent_Identity=30.6185567010309, Blast_Score=297, Evalue=3e-81,
Organism=Escherichia coli, GI145693145, Length=536, Percent_Identity=23.5074626865672, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32564422, Length=459, Percent_Identity=24.400871459695, Blast_Score=105, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564420, Length=459, Percent_Identity=24.400871459695, Blast_Score=104, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319591, Length=687, Percent_Identity=26.0553129548763, Blast_Score=214, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6319699, Length=393, Percent_Identity=24.6819338422392, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24648676, Length=617, Percent_Identity=27.8768233387358, Blast_Score=169, Evalue=2e-41,
Organism=Drosophila melanogaster, GI18859661, Length=436, Percent_Identity=24.7706422018349, Blast_Score=75, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 169096; Mature: 168965

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSASSPNLAFAAGERPAAPAIEAVLPLTPMQHGMLFHSLLDPASAVFFQQLVAEFDGA
CCCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
LDAQAFAAAWADLVDRHQSLRTAFLWERRDEPRQVVLRRARVPLEWLDWSDLGGDDARDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCHHHH
FDARLDAHLRADRERRFDPARAPLLRVAMVRRAAARHLMIVSHHHLILDGWSTGVLLGEL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCEEEEECCCCHHHHHHH
QALHAARLRRRAAALPPAPRYAAFVEHLGRAGRPCDDAFWRAMLAGFAQPTPLVGDIRRD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
AATSGDYVPCDLRLESAARRALEDAARRHRVSAAVAVFAAWAWLLARRADVPEVVYGVTV
HCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEE
AGRPAELPSAQRLVGLCINTIPLRASAPTRGDVGGWLRDVQERLARAQPHEHASLSAIQR
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ASAVPPGVPLFDSLVVYENYPIAPPPADAPLRLVHARVEERANYALTLIAEPQADGLALR
HCCCCCCCCHHHCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEE
LIVDRTRIAPHEGRRMLEQLRVVLDGIARAGEHADLAGLALLTPDAQRRMLQDWNATHAP
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCCCCC
YDRTATLHGLFARRAAQAPDAPALIDGAGTLGYGELDRLSRAVAAALDAAGVPAGAPVAV
CCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
RMLRDRHLVAALLGILRSGRAYVPLPRDLPPARVGDIVDAMSIGCVVTSAALRDETAAHL
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGRPAARLVAEEIVRGAPARESGRGGADDLAYVIFTSGSTGKPKGVMVRHRPAVNLIDWV
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCHHHHHH
NRRFGVGPSDRLLFVTSPAFDLSVYDIFGVLAAGGSIRIASDDEVADPERLARMLADEPV
HHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCC
TFWDSAPAALWQLHPLLPERVEGSRLRLVFCSGDWIPLSLPERMRGCFPGATVVALGGAT
EECCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCEEECCCHHHHHCCCCCCEEEEECCCC
EATIWSNYHVVERVEPGWRSIPYGRPIQNARYYILDRALRPVPPGIPGDLYIGGECLCDG
CEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCEEEECC
YAGQPALTAERFVPDPHAERPGARMYRTGDRARFWDDATIEFLGRDDHQVKIRGFRVELG
CCCCCCCCHHHCCCCCCCCCCCCCCEECCCCCEECCCCEEEEECCCCCEEEEEEEEEEHH
EVEAALARHPDVRDAVAVVRTGGEGGPADGRDDRALVAYAVPKPGGRASAADLLAHLRGL
HHHHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHC
LPPPMVPAHLVMLDALPVSANGKVDRRALPAPLADRAQAGGATHLVEELVAAIWADVLGL
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
ASVPVDQDFFALGGHSLRATSAIARLRVALRKELPLALLYRHPSVRELSAAIVAGGACAP
HCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCC
DAGGAQDGAPPRLSRDGPLPLSPAQERLWFLHRLEPDSPFYTIVLAAWLDGRVERAALER
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHH
AVAVVVERHEILRSHIVDIDGRPAQTPARADLPLPIRVVDLTGAADPQAEALALARAEAL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
RPFDLARALPFRVLLAPTRADRALALILMDHAAADGWSIGIFAQELLGAYDALVDGAAPA
CHHHHHHHCCEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
LLPLDAQYADLSAWQAARLGRGELERQLDYWRATLAGLPALNLPTDRPRAPTPRFAGAVV
EEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCEEE
RFHVPAASARALAALARRESCTLFMVGLAAFATVLRHRSGQDDLAIGTDLAGRTHPAAER
EEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHH
LIGFFVNQLVLRIDLSGCDSFRDALRAVRERALDGFFHQDVPFDTLVRALNPPREPGRMP
HHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC
LFQVKFVLQNTPFVTLSSRHLRVEPLDIDTGTAKYDLLATLAERPDGLAGTLEYSTDLFD
CEEEEEECCCCCEEEEECCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHH
AATAEGIAADLQAVLDLVAQNAAVGVADIARLLDAGHAQRAELGRQSLRRAGLERLRRLA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SAQGGTR
HCCCCCC
>Mature Secondary Structure 
TTSASSPNLAFAAGERPAAPAIEAVLPLTPMQHGMLFHSLLDPASAVFFQQLVAEFDGA
CCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
LDAQAFAAAWADLVDRHQSLRTAFLWERRDEPRQVVLRRARVPLEWLDWSDLGGDDARDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCHHHH
FDARLDAHLRADRERRFDPARAPLLRVAMVRRAAARHLMIVSHHHLILDGWSTGVLLGEL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCEEEEECCCCHHHHHHH
QALHAARLRRRAAALPPAPRYAAFVEHLGRAGRPCDDAFWRAMLAGFAQPTPLVGDIRRD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
AATSGDYVPCDLRLESAARRALEDAARRHRVSAAVAVFAAWAWLLARRADVPEVVYGVTV
HCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEE
AGRPAELPSAQRLVGLCINTIPLRASAPTRGDVGGWLRDVQERLARAQPHEHASLSAIQR
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ASAVPPGVPLFDSLVVYENYPIAPPPADAPLRLVHARVEERANYALTLIAEPQADGLALR
HCCCCCCCCHHHCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEE
LIVDRTRIAPHEGRRMLEQLRVVLDGIARAGEHADLAGLALLTPDAQRRMLQDWNATHAP
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCCCCC
YDRTATLHGLFARRAAQAPDAPALIDGAGTLGYGELDRLSRAVAAALDAAGVPAGAPVAV
CCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
RMLRDRHLVAALLGILRSGRAYVPLPRDLPPARVGDIVDAMSIGCVVTSAALRDETAAHL
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGRPAARLVAEEIVRGAPARESGRGGADDLAYVIFTSGSTGKPKGVMVRHRPAVNLIDWV
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCHHHHHH
NRRFGVGPSDRLLFVTSPAFDLSVYDIFGVLAAGGSIRIASDDEVADPERLARMLADEPV
HHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCC
TFWDSAPAALWQLHPLLPERVEGSRLRLVFCSGDWIPLSLPERMRGCFPGATVVALGGAT
EECCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCEEECCCHHHHHCCCCCCEEEEECCCC
EATIWSNYHVVERVEPGWRSIPYGRPIQNARYYILDRALRPVPPGIPGDLYIGGECLCDG
CEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCEEEECC
YAGQPALTAERFVPDPHAERPGARMYRTGDRARFWDDATIEFLGRDDHQVKIRGFRVELG
CCCCCCCCHHHCCCCCCCCCCCCCCEECCCCCEECCCCEEEEECCCCCEEEEEEEEEEHH
EVEAALARHPDVRDAVAVVRTGGEGGPADGRDDRALVAYAVPKPGGRASAADLLAHLRGL
HHHHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHC
LPPPMVPAHLVMLDALPVSANGKVDRRALPAPLADRAQAGGATHLVEELVAAIWADVLGL
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
ASVPVDQDFFALGGHSLRATSAIARLRVALRKELPLALLYRHPSVRELSAAIVAGGACAP
HCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCC
DAGGAQDGAPPRLSRDGPLPLSPAQERLWFLHRLEPDSPFYTIVLAAWLDGRVERAALER
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHH
AVAVVVERHEILRSHIVDIDGRPAQTPARADLPLPIRVVDLTGAADPQAEALALARAEAL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
RPFDLARALPFRVLLAPTRADRALALILMDHAAADGWSIGIFAQELLGAYDALVDGAAPA
CHHHHHHHCCEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
LLPLDAQYADLSAWQAARLGRGELERQLDYWRATLAGLPALNLPTDRPRAPTPRFAGAVV
EEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCEEE
RFHVPAASARALAALARRESCTLFMVGLAAFATVLRHRSGQDDLAIGTDLAGRTHPAAER
EEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHH
LIGFFVNQLVLRIDLSGCDSFRDALRAVRERALDGFFHQDVPFDTLVRALNPPREPGRMP
HHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC
LFQVKFVLQNTPFVTLSSRHLRVEPLDIDTGTAKYDLLATLAERPDGLAGTLEYSTDLFD
CEEEEEECCCCCEEEEECCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHH
AATAEGIAADLQAVLDLVAQNAAVGVADIARLLDAGHAQRAELGRQSLRRAGLERLRRLA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SAQGGTR
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA