Click here to switch to the map view.

The map label for this gene is tycC [H]

Identifier: 126442826

GI number: 126442826

Start: 1617640

End: 1621701

Strand: Reverse

Name: tycC [H]

Synonym: BURPS668_A1675

Alternate gene names: 126442826

Gene position: 1621701-1617640 (Counterclockwise)

Preceding gene: 126445027

Following gene: 126443154

Centisome position: 51.85

GC content: 75.85

Gene sequence:

>4062_bases
ATGAGCGCGACGAGCGAGACCGCGCTGCACGGCTTCCGGCTGTCGCCCGTGCAGCAGCGTGTGTGGACCTTGACGGACGC
GGGGCGGCTGCCGGCCGCGCAACGGGTGGTCGCACGCTTTGCGTGGACGGCCGCGCCGCCGTCGCGTGCGGCGCTCGAGG
CCGCGCTGAACGCGCTGATCGGCCGCCACGAGATCCTGCGCGCGCGCTTCGCGCGATTGCCGGAGATGCGCCTGCCGCTG
CAAACCGCGCCGGACGGCGCGCGCCTGCGGCTCGACGGCGCATGCGCGCCCGACGTGCCCGGCACGCCGGACACGCCCGA
CATGCCCGACATGCCCGACGCGGGTGCGCCGGCGCTGCACGCGGCGATGGACGCAACGGGCCTCGTGCTGTCGCTGCCGG
CGCTGTGCGCCGACGGACCGACGATGCTGCACCTCGGCGCCGCGCTCGCCGCGCGGCTCGCCGGCGACGGCGCGCGTGCC
GATGCCGACGGCCAGGCGCCGCTGCAATTCTTCGATCTCGCGCAGTGGCAGCACGATCTGCTCGCCGAGGAGGGCGCGTG
GCGCTGGCCCGACGGCGCGCTGCAGTCCGCGCACGGGCCGTGGCCCGCGCTGCCGGCGCTGCGCTCCGCGCGCGCGGCCG
CGTACCGCCCGGCGCGGCACGCGTGCGCGCTGCCCGCGGATACCGGCGCGCGCGTCGGCGCGCTTTGCGCGCGCCTCGGC
GTGACGCCGGCCGATCTACTGTGCGCCGTCTGGGCGGTGCTGCTGCACCGACTGTCGGGCGGCGACACGCTGCCGGTGGC
GATCGTTGCCGACGGTCGGCCGTTCGACGAGCTCGCCACGGCGCTCGGCCCGCTCGCCGCGCCCGTGCCGCTTTCGCTGT
CGGCCGCGCTGGGCGCGCCGGACGGCACGTTCGCCGGCCTCGCGAAAGCGGCGGCCGACGCGCGCGCGACGGCGGCCGAT
CTGCGTCATCATCTCGTCCCGCCCGACGAGGCGCGCTTCGCGCCGTTCCAGATCGAAGTGCTCGACGCGGGGCGGGCGGA
CGACGCGCTGCTGCGCGTCGTCGATGTGGCGACGGCGGGCGAGCCGGCGTTGCTGAAGCTCTCGGTGCTCGTCGGGCCCG
GCGGCGCGCTGCGCGCGGATATCGACCACGATGCCGGCGCGGTGCGCGACGGCGGTGCGATCGCGCGGCTGGCGGAGCAG
TTCGCGACGCTGCTCGACGCGGTGCTCGCGAACCCGGACGCGACGTTCGACGAGCCGGACCTGCTGGGCGCGGCGGAGCG
GCGGCTCGTCACGGAGGATTTTCAGGGGCCGCAGGTGAATCACGGCCGTTGGACGCCCGTGCATCTGGCGGTGGCCGCGG
CCGCCGCCGCGGCGCCCGATCGGCTCGCCGTGCAGGACGGCGCCGCGCGGCTGACGGCGGCGGCTCTCGAGCGCGCCGTT
CGTGCGCTCGCGGCGCGGCTGACCGCGGCGGGCGTCGCGGCGCAGACGCTTGTCGCGCTGCATCTGCCGCGCGGCGCGGC
GCTCGTGACGGCGATGCTCGCCGTGATGCGGGCGGGCGGCGTTTTTCTGCCGATGCCGCCGGAGCTGCCCGCCGCGCGCC
GGCGTTACATGCTCGAGGACAGCGGCGCGCGGATCGTGCTGACGCTGCCGGACGCCGCGGACGATCTGCCGCGGGATCTC
GCGCTCGTGTGCGTGTACCCGGGGGAGGCCGATGTCGATGTCGATGTCGACGTCGAGGCCGAAGCCGATGTCGACATCGA
CGCGCGCACGGCGGCATCCGGACCGACCGCGCGCGTCACGGCCGACGCGCCTGCCGACGCGGGCGCGGATGCGACGACCG
GCGCTTGCCCCGACGCGTGGCCTGCCCCCGACCCGACGCAGGCCGCCTACGTGCTGTACACGTCCGGCTCGACGGGGCGG
CCGAAAGGCGTCGTGGTCACGCACGGCTCGCTCGCGAACCACATGGCGTGGATGACGCGCGCGTTCCCGCTCGACGCGCA
CGACGCGGTGCTGCAAAAGACCTCGGCCGCGTTCGACGCGTCGATCTGGGAATTCTTCCTGCCGCTGCTGGCGGGCGCGC
GGCTCGTGATGGCGCCGCCCGGCCTCGAGCGCGACGTGCCGGCGCTCGTCGCGACGCTCGCGCGCGAGCGCATCACCGTG
CTGCAGCTCGTGCCGAGCCTGCTGCGCGTGCTCGTCGACGCGCCGGGCTTCGGCGCGTGCGACGCGCTGCGATGCGTGTT
CTGCGGCGGCGAAGCGCTGACGGCCGATCTCGCCCGGCGCTTCGCCGCCGCGCACCGCGCGGCGCTCGTCAACCTGTACG
GCCCGACCGAGACGACGATCCAGGTTTGCGCGGAGCGGGTCGACGCGGCCGACGATCCCGTGCCGGTCGGCCGCCCGATC
GACAACGTCCGGCTGTACGTCGTCGATTCGCGCAACCGGCTCTCGCCCGTGGGCGTGCGCGGCGAGATCCTGATCGGCGG
CGCGGCGCCCGCGCGCGGCTATCTCGATCGGCCGGCGCTCACCGCCGCGCGCTTCGTCGCCGATCCGATCGATCCGCGCG
CGCCGCGCGTCTATCGCAGCGGCGACGTGGGCGCGTGGCGCGCCGACGGCCGGCTCGACTTTTTCGGCCGCGCCGACGAT
CAGGTGAAACTGCGCGGCTACCGGATCGAGCTCGGCGAAGTGGAGGCGACGATCGCCCGGCATCCGGACGTCGCCAACGC
GGCGGCGAGCGTCGATCTGGACGCGAACGGCATCGCGCGGCTCGTCTGCGCGTACGACTGCCGCGCCGGCCGCGGCGTCG
AGCCCGCGCCGCTGCGCGCGTGGCTCGCGACGCAGTTGCCGGACTACATGGTTCCCGGCCGGTGCCGCCGGCTCGACGCG
CTGCCGCGCAACGCGAGCGGCAAGATCGACCGCGCGGCGCTGGCGCGCGGCGTCGACGCGCCGCGTGACGGCGCCGCGCC
GCGCGATCCGGTCGAGCTGCGGCTCGAGCGCGTGTGGGAGGCGGTGCTCGACGTTCAGCCGGTCGGCGTCGATCGGACGT
TCTTCGATCTCGGCGGCCATTCACTGCTGGCCGTGCGGCTGATGGCGGAAGTCAAGCGCGAGTTCGGCTGCGATCTGCCG
CTTGCGTCGCTGTTCGAGGCGCCCACCGTCGCCGCGCAGGCGGCGCTCATCCGGCAGCGCGAGCGGGCGCACCCGGTGGT
GGTGCGCGTCAATCGCGGCATCGACGGCGAGCGCCCGGTGTTCCTCGTGCACCCGACGGGCGGCAACGTGCTTTGCTACC
GCGATCTCGCGCGGCGGCTCGGGCCGGCCCGGCCGATCTACGCGCTGCAGGACCCGGGCCTCGAGGGCGACGCCGGCTAC
GACAGCGTCGAGGAGCTGGCGGCGCGCCATATCGCGCACATCCGCCCGCTCGCGGGCGACGGCCCGTATTACCTCGCGGG
CTGGTCGTCGGGCGGCGTCGTCGCGTTCGAGATCGCGCGCCAGTTGCTCGCGCAGCGGTGCGAGGTCGGGCTGCTCGCGT
TGATCGACAGCGTCGCGTCCGACGGCGCGCAGCCGGCCCCGCGCACCGACGCCGAGCTGATCGGCTCGATCGGCCGGCTG
CTCGCGTTCGCGGCGGGCGTCGACGCGCCGGATCTGGCGGCGCTCGAACCGTCGGCCGCGATGGCGCGGCTGCGCGAGCT
GGCCGTCGCGGCCGGCTCGCTGCCGCCCGATGCGCCGCCCGAGCGGATGCGCCGGCTTTTCGACGTCTTCCGCCGCAACG
CCGCCGCCGTGCGCCGCTACCGGCCCGGGCCGTATCCGCGCCGCGTGCTGCTGCTGCGCGCAACGCAGCCGCTGCCCGAA
CCGGTGCGCGACGCCGCCGCGCGCCAGCGCGGCGATTCGCCGGAGCTGGGCTGGGAGCGCGTCGCGGTGGTGAGCCGCTG
CGACATCCCCGCGCATCATCTGTCGATCGTCCACGAGCCGGCCGCGGCGCTCGTCGGCGCGCGGATTCGCGACGCGCTGC
ACGCGGCGGACCGCATCGAGGCGATCGGCGAGCGGGTTTTCTTCACGTTGCTCGGACACTGA

Upstream 100 bases:

>100_bases
GCCGCGCGCCGTTTACCGGCGAGCGTCGCGTGCTGGCCGCGATGGGGGACGCCGTCGAGCTGGATGCGCGCGAGATGGCG
GCGCTTCGGGAGCGTCTCGC

Downstream 100 bases:

>100_bases
TGGAGGCGAGCCGACCGATGACGACAAGCGCTTCTTCGCCGAACCTTGCTTTCGCCGCCGGCGAGCGGCCCGCCGCGCCG
GCGATCGAAGCGGTGCTGCC

Product: CtaG

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 1353; Mature: 1352

Protein sequence:

>1353_residues
MSATSETALHGFRLSPVQQRVWTLTDAGRLPAAQRVVARFAWTAAPPSRAALEAALNALIGRHEILRARFARLPEMRLPL
QTAPDGARLRLDGACAPDVPGTPDTPDMPDMPDAGAPALHAAMDATGLVLSLPALCADGPTMLHLGAALAARLAGDGARA
DADGQAPLQFFDLAQWQHDLLAEEGAWRWPDGALQSAHGPWPALPALRSARAAAYRPARHACALPADTGARVGALCARLG
VTPADLLCAVWAVLLHRLSGGDTLPVAIVADGRPFDELATALGPLAAPVPLSLSAALGAPDGTFAGLAKAAADARATAAD
LRHHLVPPDEARFAPFQIEVLDAGRADDALLRVVDVATAGEPALLKLSVLVGPGGALRADIDHDAGAVRDGGAIARLAEQ
FATLLDAVLANPDATFDEPDLLGAAERRLVTEDFQGPQVNHGRWTPVHLAVAAAAAAAPDRLAVQDGAARLTAAALERAV
RALAARLTAAGVAAQTLVALHLPRGAALVTAMLAVMRAGGVFLPMPPELPAARRRYMLEDSGARIVLTLPDAADDLPRDL
ALVCVYPGEADVDVDVDVEAEADVDIDARTAASGPTARVTADAPADAGADATTGACPDAWPAPDPTQAAYVLYTSGSTGR
PKGVVVTHGSLANHMAWMTRAFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPPGLERDVPALVATLARERITV
LQLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARRFAAAHRAALVNLYGPTETTIQVCAERVDAADDPVPVGRPI
DNVRLYVVDSRNRLSPVGVRGEILIGGAAPARGYLDRPALTAARFVADPIDPRAPRVYRSGDVGAWRADGRLDFFGRADD
QVKLRGYRIELGEVEATIARHPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRAWLATQLPDYMVPGRCRRLDA
LPRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWEAVLDVQPVGVDRTFFDLGGHSLLAVRLMAEVKREFGCDLP
LASLFEAPTVAAQAALIRQRERAHPVVVRVNRGIDGERPVFLVHPTGGNVLCYRDLARRLGPARPIYALQDPGLEGDAGY
DSVEELAARHIAHIRPLAGDGPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVASDGAQPAPRTDAELIGSIGRL
LAFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPPERMRRLFDVFRRNAAAVRRYRPGPYPRRVLLLRATQPLPE
PVRDAAARQRGDSPELGWERVAVVSRCDIPAHHLSIVHEPAAALVGARIRDALHAADRIEAIGERVFFTLLGH

Sequences:

>Translated_1353_residues
MSATSETALHGFRLSPVQQRVWTLTDAGRLPAAQRVVARFAWTAAPPSRAALEAALNALIGRHEILRARFARLPEMRLPL
QTAPDGARLRLDGACAPDVPGTPDTPDMPDMPDAGAPALHAAMDATGLVLSLPALCADGPTMLHLGAALAARLAGDGARA
DADGQAPLQFFDLAQWQHDLLAEEGAWRWPDGALQSAHGPWPALPALRSARAAAYRPARHACALPADTGARVGALCARLG
VTPADLLCAVWAVLLHRLSGGDTLPVAIVADGRPFDELATALGPLAAPVPLSLSAALGAPDGTFAGLAKAAADARATAAD
LRHHLVPPDEARFAPFQIEVLDAGRADDALLRVVDVATAGEPALLKLSVLVGPGGALRADIDHDAGAVRDGGAIARLAEQ
FATLLDAVLANPDATFDEPDLLGAAERRLVTEDFQGPQVNHGRWTPVHLAVAAAAAAAPDRLAVQDGAARLTAAALERAV
RALAARLTAAGVAAQTLVALHLPRGAALVTAMLAVMRAGGVFLPMPPELPAARRRYMLEDSGARIVLTLPDAADDLPRDL
ALVCVYPGEADVDVDVDVEAEADVDIDARTAASGPTARVTADAPADAGADATTGACPDAWPAPDPTQAAYVLYTSGSTGR
PKGVVVTHGSLANHMAWMTRAFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPPGLERDVPALVATLARERITV
LQLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARRFAAAHRAALVNLYGPTETTIQVCAERVDAADDPVPVGRPI
DNVRLYVVDSRNRLSPVGVRGEILIGGAAPARGYLDRPALTAARFVADPIDPRAPRVYRSGDVGAWRADGRLDFFGRADD
QVKLRGYRIELGEVEATIARHPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRAWLATQLPDYMVPGRCRRLDA
LPRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWEAVLDVQPVGVDRTFFDLGGHSLLAVRLMAEVKREFGCDLP
LASLFEAPTVAAQAALIRQRERAHPVVVRVNRGIDGERPVFLVHPTGGNVLCYRDLARRLGPARPIYALQDPGLEGDAGY
DSVEELAARHIAHIRPLAGDGPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVASDGAQPAPRTDAELIGSIGRL
LAFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPPERMRRLFDVFRRNAAAVRRYRPGPYPRRVLLLRATQPLPE
PVRDAAARQRGDSPELGWERVAVVSRCDIPAHHLSIVHEPAAALVGARIRDALHAADRIEAIGERVFFTLLGH
>Mature_1352_residues
SATSETALHGFRLSPVQQRVWTLTDAGRLPAAQRVVARFAWTAAPPSRAALEAALNALIGRHEILRARFARLPEMRLPLQ
TAPDGARLRLDGACAPDVPGTPDTPDMPDMPDAGAPALHAAMDATGLVLSLPALCADGPTMLHLGAALAARLAGDGARAD
ADGQAPLQFFDLAQWQHDLLAEEGAWRWPDGALQSAHGPWPALPALRSARAAAYRPARHACALPADTGARVGALCARLGV
TPADLLCAVWAVLLHRLSGGDTLPVAIVADGRPFDELATALGPLAAPVPLSLSAALGAPDGTFAGLAKAAADARATAADL
RHHLVPPDEARFAPFQIEVLDAGRADDALLRVVDVATAGEPALLKLSVLVGPGGALRADIDHDAGAVRDGGAIARLAEQF
ATLLDAVLANPDATFDEPDLLGAAERRLVTEDFQGPQVNHGRWTPVHLAVAAAAAAAPDRLAVQDGAARLTAAALERAVR
ALAARLTAAGVAAQTLVALHLPRGAALVTAMLAVMRAGGVFLPMPPELPAARRRYMLEDSGARIVLTLPDAADDLPRDLA
LVCVYPGEADVDVDVDVEAEADVDIDARTAASGPTARVTADAPADAGADATTGACPDAWPAPDPTQAAYVLYTSGSTGRP
KGVVVTHGSLANHMAWMTRAFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPPGLERDVPALVATLARERITVL
QLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARRFAAAHRAALVNLYGPTETTIQVCAERVDAADDPVPVGRPID
NVRLYVVDSRNRLSPVGVRGEILIGGAAPARGYLDRPALTAARFVADPIDPRAPRVYRSGDVGAWRADGRLDFFGRADDQ
VKLRGYRIELGEVEATIARHPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRAWLATQLPDYMVPGRCRRLDAL
PRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWEAVLDVQPVGVDRTFFDLGGHSLLAVRLMAEVKREFGCDLPL
ASLFEAPTVAAQAALIRQRERAHPVVVRVNRGIDGERPVFLVHPTGGNVLCYRDLARRLGPARPIYALQDPGLEGDAGYD
SVEELAARHIAHIRPLAGDGPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVASDGAQPAPRTDAELIGSIGRLL
AFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPPERMRRLFDVFRRNAAAVRRYRPGPYPRRVLLLRATQPLPEP
VRDAAARQRGDSPELGWERVAVVSRCDIPAHHLSIVHEPAAALVGARIRDALHAADRIEAIGERVFFTLLGH

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=438, Percent_Identity=25.5707762557078, Blast_Score=121, Evalue=4e-27,
Organism=Homo sapiens, GI187761345, Length=571, Percent_Identity=24.3432574430823, Blast_Score=115, Evalue=4e-25,
Organism=Homo sapiens, GI187761343, Length=571, Percent_Identity=24.3432574430823, Blast_Score=115, Evalue=4e-25,
Organism=Homo sapiens, GI42544132, Length=500, Percent_Identity=24.4, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI38505220, Length=507, Percent_Identity=25.6410256410256, Blast_Score=95, Evalue=6e-19,
Organism=Homo sapiens, GI122937307, Length=499, Percent_Identity=24.4488977955912, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI157311624, Length=503, Percent_Identity=23.8568588469185, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI157311622, Length=503, Percent_Identity=23.8568588469185, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI41872631, Length=222, Percent_Identity=32.4324324324324, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI58082049, Length=511, Percent_Identity=24.0704500978474, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI115511026, Length=511, Percent_Identity=22.7005870841487, Blast_Score=83, Evalue=2e-15,
Organism=Escherichia coli, GI1786801, Length=947, Percent_Identity=32.2069693769799, Blast_Score=348, Evalue=2e-96,
Organism=Escherichia coli, GI145693145, Length=557, Percent_Identity=26.7504488330341, Blast_Score=116, Evalue=8e-27,
Organism=Escherichia coli, GI1788107, Length=568, Percent_Identity=24.1197183098592, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1790505, Length=534, Percent_Identity=24.5318352059925, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1786810, Length=563, Percent_Identity=24.6891651865009, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI221142682, Length=525, Percent_Identity=22.4761904761905, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1789201, Length=366, Percent_Identity=26.775956284153, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17556356, Length=430, Percent_Identity=27.6744186046512, Blast_Score=131, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71994703, Length=564, Percent_Identity=21.9858156028369, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994690, Length=564, Percent_Identity=21.9858156028369, Blast_Score=108, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994694, Length=564, Percent_Identity=21.9858156028369, Blast_Score=108, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=568, Percent_Identity=22.1830985915493, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32564422, Length=403, Percent_Identity=26.302729528536, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32564420, Length=403, Percent_Identity=26.302729528536, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538037, Length=528, Percent_Identity=21.0227272727273, Blast_Score=87, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319591, Length=910, Percent_Identity=25.4945054945055, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6319699, Length=555, Percent_Identity=20.5405405405405, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648676, Length=618, Percent_Identity=29.126213592233, Blast_Score=197, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24582852, Length=462, Percent_Identity=24.025974025974, Blast_Score=107, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24581924, Length=367, Percent_Identity=25.6130790190736, Blast_Score=92, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24648257, Length=247, Percent_Identity=29.1497975708502, Blast_Score=79, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 142572; Mature: 142441

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATSETALHGFRLSPVQQRVWTLTDAGRLPAAQRVVARFAWTAAPPSRAALEAALNALI
CCCCCCHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GRHEILRARFARLPEMRLPLQTAPDGARLRLDGACAPDVPGTPDTPDMPDMPDAGAPALH
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH
AAMDATGLVLSLPALCADGPTMLHLGAALAARLAGDGARADADGQAPLQFFDLAQWQHDL
HHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
LAEEGAWRWPDGALQSAHGPWPALPALRSARAAAYRPARHACALPADTGARVGALCARLG
HHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHC
VTPADLLCAVWAVLLHRLSGGDTLPVAIVADGRPFDELATALGPLAAPVPLSLSAALGAP
CCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHCCCC
DGTFAGLAKAAADARATAADLRHHLVPPDEARFAPFQIEVLDAGRADDALLRVVDVATAG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCC
EPALLKLSVLVGPGGALRADIDHDAGAVRDGGAIARLAEQFATLLDAVLANPDATFDEPD
CCCEEEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
LLGAAERRLVTEDFQGPQVNHGRWTPVHLAVAAAAAAAPDRLAVQDGAARLTAAALERAV
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHH
RALAARLTAAGVAAQTLVALHLPRGAALVTAMLAVMRAGGVFLPMPPELPAARRRYMLED
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHEEEEC
SGARIVLTLPDAADDLPRDLALVCVYPGEADVDVDVDVEAEADVDIDARTAASGPTARVT
CCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEE
ADAPADAGADATTGACPDAWPAPDPTQAAYVLYTSGSTGRPKGVVVTHGSLANHMAWMTR
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHH
AFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPPGLERDVPALVATLARERITV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHH
LQLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARRFAAAHRAALVNLYGPTETTI
HHHHHHHHHHHHCCCCCCHHHHHHEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCHHHH
QVCAERVDAADDPVPVGRPIDNVRLYVVDSRNRLSPVGVRGEILIGGAAPARGYLDRPAL
HHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHH
TAARFVADPIDPRAPRVYRSGDVGAWRADGRLDFFGRADDQVKLRGYRIELGEVEATIAR
HHHHHHCCCCCCCCCCEEECCCCCCEECCCCEEECCCCCCEEEEEEEEEEECCHHHHHHC
HPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRAWLATQLPDYMVPGRCRRLDA
CCCHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHC
LPRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWEAVLDVQPVGVDRTFFDLGGH
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCC
SLLAVRLMAEVKREFGCDLPLASLFEAPTVAAQAALIRQRERAHPVVVRVNRGIDGERPV
HHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCE
FLVHPTGGNVLCYRDLARRLGPARPIYALQDPGLEGDAGYDSVEELAARHIAHIRPLAGD
EEEECCCCCEEEHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
GPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVASDGAQPAPRTDAELIGSIGRL
CCEEEEECCCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LAFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPPERMRRLFDVFRRNAAAVRRY
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
RPGPYPRRVLLLRATQPLPEPVRDAAARQRGDSPELGWERVAVVSRCDIPAHHLSIVHEP
CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
AAALVGARIRDALHAADRIEAIGERVFFTLLGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SATSETALHGFRLSPVQQRVWTLTDAGRLPAAQRVVARFAWTAAPPSRAALEAALNALI
CCCCCHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GRHEILRARFARLPEMRLPLQTAPDGARLRLDGACAPDVPGTPDTPDMPDMPDAGAPALH
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH
AAMDATGLVLSLPALCADGPTMLHLGAALAARLAGDGARADADGQAPLQFFDLAQWQHDL
HHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
LAEEGAWRWPDGALQSAHGPWPALPALRSARAAAYRPARHACALPADTGARVGALCARLG
HHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHC
VTPADLLCAVWAVLLHRLSGGDTLPVAIVADGRPFDELATALGPLAAPVPLSLSAALGAP
CCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHCCCC
DGTFAGLAKAAADARATAADLRHHLVPPDEARFAPFQIEVLDAGRADDALLRVVDVATAG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCC
EPALLKLSVLVGPGGALRADIDHDAGAVRDGGAIARLAEQFATLLDAVLANPDATFDEPD
CCCEEEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
LLGAAERRLVTEDFQGPQVNHGRWTPVHLAVAAAAAAAPDRLAVQDGAARLTAAALERAV
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHH
RALAARLTAAGVAAQTLVALHLPRGAALVTAMLAVMRAGGVFLPMPPELPAARRRYMLED
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHEEEEC
SGARIVLTLPDAADDLPRDLALVCVYPGEADVDVDVDVEAEADVDIDARTAASGPTARVT
CCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEE
ADAPADAGADATTGACPDAWPAPDPTQAAYVLYTSGSTGRPKGVVVTHGSLANHMAWMTR
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHH
AFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPPGLERDVPALVATLARERITV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHH
LQLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARRFAAAHRAALVNLYGPTETTI
HHHHHHHHHHHHCCCCCCHHHHHHEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCHHHH
QVCAERVDAADDPVPVGRPIDNVRLYVVDSRNRLSPVGVRGEILIGGAAPARGYLDRPAL
HHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHH
TAARFVADPIDPRAPRVYRSGDVGAWRADGRLDFFGRADDQVKLRGYRIELGEVEATIAR
HHHHHHCCCCCCCCCCEEECCCCCCEECCCCEEECCCCCCEEEEEEEEEEECCHHHHHHC
HPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRAWLATQLPDYMVPGRCRRLDA
CCCHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHC
LPRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWEAVLDVQPVGVDRTFFDLGGH
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCC
SLLAVRLMAEVKREFGCDLPLASLFEAPTVAAQAALIRQRERAHPVVVRVNRGIDGERPV
HHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCE
FLVHPTGGNVLCYRDLARRLGPARPIYALQDPGLEGDAGYDSVEELAARHIAHIRPLAGD
EEEECCCCCEEEHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
GPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVASDGAQPAPRTDAELIGSIGRL
CCEEEEECCCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LAFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPPERMRRLFDVFRRNAAAVRRY
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
RPGPYPRRVLLLRATQPLPEPVRDAAARQRGDSPELGWERVAVVSRCDIPAHHLSIVHEP
CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
AAALVGARIRDALHAADRIEAIGERVFFTLLGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]