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The map label for this gene is iorA [H]

Identifier: 126443054

GI number: 126443054

Start: 976193

End: 976654

Strand: Reverse

Name: iorA [H]

Synonym: BURPS668_A1007

Alternate gene names: 126443054

Gene position: 976654-976193 (Counterclockwise)

Preceding gene: 126442389

Following gene: 126443756

Centisome position: 31.23

GC content: 70.13

Gene sequence:

>462_bases
ATGTCTACCTCGTTTGTGCTGAACGGCAAGAACCTCACGCTGGACGCCGATCCCGCGATGCCGCTCCTCTGGGCGATCCG
CGAGGACGCGGGCCTGCACGGCACGAAGTTCGGCTGCGGCGCCGCGCAGTGCGGCGCGTGCACCGTGCATCTCGAAGGCC
AGGCGGTGCGCTCGTGCGTGCTGCCGCTCGCGGCCGTCGCCGGCAAGCGCGTGACGACCATCGAAGGACTCGCGAGCCGG
CCCGCGAAGGCCGTCCAGGCTGCGTGGGTCAAGCTGCAGGTGCCGCAGTGCGGCTACTGCCAGTCCGGCCAGATCATGTC
GGCGACCGCGCTCCTCGAACAGAACCCGGCGCCGACCGACGCCGACATCGACGCCGCGATGAACGGCAACATCTGCCGTT
GCGCGACCTACACCCGCATCCGCGCCGCGATTCACGAAGCGGCCGCCACCCTGAAGGCCTGA

Upstream 100 bases:

>100_bases
ATATTTTTGCAGGATTGTGTAAACGCAACGGCGGTCCGTCCCTCACACTGCCGGCTATCACCCGGCGCCAAGTCCGGGCA
TTCCCCCACGGAGATTGTCC

Downstream 100 bases:

>100_bases
CGATGACGACCGACCTCGATCTCCCGGACGCCGTGCGCGCGTCCCGCCGCACGTTCCTGAAAGCCGCCGGCGCCGCCGCG
GCCGTCGGCCTCACGATCGG

Product: putative oxidoreductase, iron-sulfur cluster-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MSTSFVLNGKNLTLDADPAMPLLWAIREDAGLHGTKFGCGAAQCGACTVHLEGQAVRSCVLPLAAVAGKRVTTIEGLASR
PAKAVQAAWVKLQVPQCGYCQSGQIMSATALLEQNPAPTDADIDAAMNGNICRCATYTRIRAAIHEAAATLKA

Sequences:

>Translated_153_residues
MSTSFVLNGKNLTLDADPAMPLLWAIREDAGLHGTKFGCGAAQCGACTVHLEGQAVRSCVLPLAAVAGKRVTTIEGLASR
PAKAVQAAWVKLQVPQCGYCQSGQIMSATALLEQNPAPTDADIDAAMNGNICRCATYTRIRAAIHEAAATLKA
>Mature_152_residues
STSFVLNGKNLTLDADPAMPLLWAIREDAGLHGTKFGCGAAQCGACTVHLEGQAVRSCVLPLAAVAGKRVTTIEGLASRP
AKAVQAAWVKLQVPQCGYCQSGQIMSATALLEQNPAPTDADIDAAMNGNICRCATYTRIRAAIHEAAATLKA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=149, Percent_Identity=37.5838926174497, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI71773480, Length=95, Percent_Identity=34.7368421052632, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786480, Length=169, Percent_Identity=39.6449704142012, Blast_Score=110, Evalue=3e-26,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=37.8378378378378, Blast_Score=86, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=156, Percent_Identity=39.7435897435897, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=37.9084967320261, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=37.2549019607843, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI17737937, Length=156, Percent_Identity=38.4615384615385, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647199, Length=159, Percent_Identity=37.1069182389937, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647201, Length=159, Percent_Identity=35.8490566037736, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647193, Length=164, Percent_Identity=35.9756097560976, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15895; Mature: 15764

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSFVLNGKNLTLDADPAMPLLWAIREDAGLHGTKFGCGAAQCGACTVHLEGQAVRSCV
CCCEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHH
LPLAAVAGKRVTTIEGLASRPAKAVQAAWVKLQVPQCGYCQSGQIMSATALLEQNPAPTD
HHHHHHCCCCEEEHHHHHCCCHHHHHEEEEEEECCCCCCCCCCCEEEHHHHHHCCCCCCC
ADIDAAMNGNICRCATYTRIRAAIHEAAATLKA
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STSFVLNGKNLTLDADPAMPLLWAIREDAGLHGTKFGCGAAQCGACTVHLEGQAVRSCV
CCEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHH
LPLAAVAGKRVTTIEGLASRPAKAVQAAWVKLQVPQCGYCQSGQIMSATALLEQNPAPTD
HHHHHHCCCCEEEHHHHHCCCHHHHHEEEEEEECCCCCCCCCCCEEEHHHHHHCCCCCCC
ADIDAAMNGNICRCATYTRIRAAIHEAAATLKA
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]