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The map label for this gene is iorB [H]

Identifier: 126443756

GI number: 126443756

Start: 973959

End: 976190

Strand: Reverse

Name: iorB [H]

Synonym: BURPS668_A1006

Alternate gene names: 126443756

Gene position: 976190-973959 (Counterclockwise)

Preceding gene: 126443054

Following gene: 126444075

Centisome position: 31.21

GC content: 72.45

Gene sequence:

>2232_bases
ATGACGACCGACCTCGATCTCCCGGACGCCGTGCGCGCGTCCCGCCGCACGTTCCTGAAAGCCGCCGGCGCCGCCGCGGC
CGTCGGCCTCACGATCGGCTTCGAGTGGCTCGACGCGAGCCGCCCGGCGCTCGGCGCGACCGCGCCGGCCGCACCCGCCG
GCGACGCGGCCGGCGCGTTCGCGCCGAACGCGTTCCTGCGCGTCGCGCCGGACAACAGCGTGACCGTGATCGCGAAGCAT
GTCGAGATGGGCCAGGGCGCGTACACCGGCATCGCGACGATCGTCGCCGAAGAGCTCGACGCGAACTGGCGCGACGTGCG
CGTCGAGAGCGCGCCCGCCGACGCGTCGCGCTACGCGAACCTGCAGTTCGGCAAGCTGCAGGGCACGGGCGGCAGCTCGG
CGATGGCGAACTCGTGGATGCAACTGCGCGAGGCGGGCGCGAAGGCGCGTGCGATGCTCGTGTCCGCGGCCGCCGCGCAA
TGGAACGTGCCCGCCGCTGAGCTGACGACGGGCGACGGCGTCGTGCGCCACGCGGCGAGCCGGCGCGAGGCCACCTACGG
CTCGCTCGCGACCGCCGCGGCCGCGCTGCCCGTGCCGGAGCAGGTCACGCTGAAGTCGCCGAGCGATTTCCGGCTGATCG
GCAAGCCGGTGCCGCGTGTCGACGCGCGCGCGAAATCCGACGGCACCGCGCAGTTCACGATCGACGTGGCGATGCCCGGC
ATGCTCGTCGCGCTGCTGCAGCGCCCGCCCGTCTTCGGCGGCAAGGTGAAATCGTTCGACGCGAGCGCGGCGAAGGCGGT
GCCGGGCGTCGTGGCGGTCGTGCAGGTCGAGCGCGGCGTGGCGGTCGTCGCGAAGGGTTTCTGGGCCGCGAAGCAAGGCC
GCGACGCGCTGAAGGTCGAATGGGACGAATCGGGCGCGGAGAAGCGCAGCTCCGACGCGATCATGCGCGAGTACCGGCAG
CTCGCCGAGCGCCCGGGCGCGTCCGCACGCCGCGACGGCGATGCCGAGCACGCGCTCGCCGGCGCGGCGAAGCGGCTCCG
CGCGTCGTACGAGTTCCCGTACCTCGCGCACGCGCCGATGGAGCCGCTCGACGCGGTCGTCAAGCTGAGCGCCGATCGTT
GCGAGATCTGGGCGGGCGACCAGTTCCAGACGATCGACCAGGGCAACGCGGCGCGCGTCGCGGGGCTCGATCCGTCGCAG
GTCCAGATCCACACGTTGTATGCGGGCGGCAGCTTCGGCCGGCGCGCGAACGCGTGGTCGGACTACGTCGTCGAGGCCGT
GTCGATCGCGAAGGCGCTCGGCGCGAACGGCACGCCCGTCAAGCTGCAATGGACGCGCGAGGACGACATCCACGGCGGCC
TCTATCGGCCGATGTACTTCCACAAGCTCGACGCGGCGCTGTCGAAGGACGGCAAGCTCGTCGGCTGGCGGCACCGGATC
GTCGGCCAGTCGATCCTCGCCGGCACGCCGTTCGAGGCGGTGATGGTGAAGAACGGCATCGACCAGACCTCCGTCGAGGG
CGCGGCGAACCTGCCTTACGCGATCCCGAACGTATCGGTCGAGCTGACGACGACGCGATCCGCCGTGCCCGTGCTGTGGT
GGCGCGTGGTCGGCAGCTCGCACACCGCGTATGCGGTCGAGGCGTTCATCGACGAGGCCGCGCACGCGGCCGGCAAGGAT
CCGTACCTGTTCCGCCGCGACCTGCTCGCGCACGCGCCGCGCCTGAAGGGCGTGCTCGAGCTCGCCGCCGAGAAGGCCGG
CTGGGACCCGGGCAAGCCGCTGCCGAAGGGTCGCGGGCGCGGGATCGCCGTCGCCGAGGCGTTCAAGAGCTATGTCGCGC
AGGTCGCCGAAGTGTCCGTCGACGAGCACGGCGCCGTGAAGGTCGAGCGCGTCGTCTGCGCGCTCGACTGCGGCACCGCG
ATCAACCCGGACGTGATCGCCGCGCAGATGGAAGGCGGCATCGGCTTCGGGCTCGGCGCGGTGCTGCACGGCGCGATCAC
GCTGAAGGACGGCAAGGTCGAGCAGAACAACTTCGACGGCTACCGCGTGCTGCGGATCGCCGAGATGCCGAAGGTCGAGG
TGTACATCGTGCCGTCGGGCGAGGCGCCGACGGGCGTCGGCGAACCGGGCGTCGCGCCGATCGGCCCGGCCGTCGCGAAC
GCGATCTTCGCGGCGACGGGCAAGCGCCATTACGCGCTGCCGTTCCCGGCGGCGGGAGAGGCCACGGCCTGA

Upstream 100 bases:

>100_bases
ACATCGACGCCGCGATGAACGGCAACATCTGCCGTTGCGCGACCTACACCCGCATCCGCGCCGCGATTCACGAAGCGGCC
GCCACCCTGAAGGCCTGACG

Downstream 100 bases:

>100_bases
CGGGCGCGCGGCGACCGGCGGCGGCGGTCGGCGACGCGCGCCGCCGGTCGGCGGCCCCGCGAAACCGCCGGCGCGCCGCA
CCCGGTGTGCGTCGCCGGAG

Product: aldehyde oxidase/xanthine dehydrogenase family protein, molybdopterin-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 743; Mature: 742

Protein sequence:

>743_residues
MTTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAFAPNAFLRVAPDNSVTVIAKH
VEMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYANLQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQ
WNVPAAELTTGDGVVRHAASRREATYGSLATAAAALPVPEQVTLKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVAMPG
MLVALLQRPPVFGGKVKSFDASAAKAVPGVVAVVQVERGVAVVAKGFWAAKQGRDALKVEWDESGAEKRSSDAIMREYRQ
LAERPGASARRDGDAEHALAGAAKRLRASYEFPYLAHAPMEPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQ
VQIHTLYAGGSFGRRANAWSDYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHKLDAALSKDGKLVGWRHRI
VGQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSSHTAYAVEAFIDEAAHAAGKD
PYLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGRGIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTA
INPDVIAAQMEGGIGFGLGAVLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVAN
AIFAATGKRHYALPFPAAGEATA

Sequences:

>Translated_743_residues
MTTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAFAPNAFLRVAPDNSVTVIAKH
VEMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYANLQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQ
WNVPAAELTTGDGVVRHAASRREATYGSLATAAAALPVPEQVTLKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVAMPG
MLVALLQRPPVFGGKVKSFDASAAKAVPGVVAVVQVERGVAVVAKGFWAAKQGRDALKVEWDESGAEKRSSDAIMREYRQ
LAERPGASARRDGDAEHALAGAAKRLRASYEFPYLAHAPMEPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQ
VQIHTLYAGGSFGRRANAWSDYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHKLDAALSKDGKLVGWRHRI
VGQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSSHTAYAVEAFIDEAAHAAGKD
PYLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGRGIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTA
INPDVIAAQMEGGIGFGLGAVLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVAN
AIFAATGKRHYALPFPAAGEATA
>Mature_742_residues
TTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAFAPNAFLRVAPDNSVTVIAKHV
EMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYANLQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQW
NVPAAELTTGDGVVRHAASRREATYGSLATAAAALPVPEQVTLKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVAMPGM
LVALLQRPPVFGGKVKSFDASAAKAVPGVVAVVQVERGVAVVAKGFWAAKQGRDALKVEWDESGAEKRSSDAIMREYRQL
AERPGASARRDGDAEHALAGAAKRLRASYEFPYLAHAPMEPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQV
QIHTLYAGGSFGRRANAWSDYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHKLDAALSKDGKLVGWRHRIV
GQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSSHTAYAVEAFIDEAAHAAGKDP
YLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGRGIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTAI
NPDVIAAQMEGGIGFGLGAVLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVANA
IFAATGKRHYALPFPAAGEATA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 78014; Mature: 77883

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAF
CCCCCCCCHHHHHHHHHHHHHCCCHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
APNAFLRVAPDNSVTVIAKHVEMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYAN
CCCCEEEECCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCC
LQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQWNVPAAELTTGDGVVRHAAS
EEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHEECCCHHHHHHHH
RREATYGSLATAAAALPVPEQVTLKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVAMPG
HHHCHHHHHHHHHHHCCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCHH
MLVALLQRPPVFGGKVKSFDASAAKAVPGVVAVVQVERGVAVVAKGFWAAKQGRDALKVE
HHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCEEEEECCHHHHCCCCCCEEEE
WDESGAEKRSSDAIMREYRQLAERPGASARRDGDAEHALAGAAKRLRASYEFPYLAHAPM
ECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCC
EPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQVQIHTLYAGGSFGRRANAWS
CHHHHHHHCCCCCEEEECCCCEEECCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCHH
DYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHKLDAALSKDGKLVGWRHRI
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHH
VGQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSS
HCCHHHCCCCHHHHEECCCCCCCCCCCCCCCCEECCCCEEEEEECCCCHHEEEEEECCCC
HTAYAVEAFIDEAAHAAGKDPYLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTAINPDVIAAQMEGGIGFGLGA
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCHHH
VLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVAN
HHCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
AIFAATGKRHYALPFPAAGEATA
HHHHHCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
TTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAF
CCCCCCCHHHHHHHHHHHHHCCCHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
APNAFLRVAPDNSVTVIAKHVEMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYAN
CCCCEEEECCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCC
LQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQWNVPAAELTTGDGVVRHAAS
EEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHEECCCHHHHHHHH
RREATYGSLATAAAALPVPEQVTLKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVAMPG
HHHCHHHHHHHHHHHCCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCHH
MLVALLQRPPVFGGKVKSFDASAAKAVPGVVAVVQVERGVAVVAKGFWAAKQGRDALKVE
HHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCEEEEECCHHHHCCCCCCEEEE
WDESGAEKRSSDAIMREYRQLAERPGASARRDGDAEHALAGAAKRLRASYEFPYLAHAPM
ECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCC
EPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQVQIHTLYAGGSFGRRANAWS
CHHHHHHHCCCCCEEEECCCCEEECCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCHH
DYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHKLDAALSKDGKLVGWRHRI
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHH
VGQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSS
HCCHHHCCCCHHHHEECCCCCCCCCCCCCCCCEECCCCEEEEEECCCCHHEEEEEECCCC
HTAYAVEAFIDEAAHAAGKDPYLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTAINPDVIAAQMEGGIGFGLGA
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCHHH
VLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVAN
HHCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
AIFAATGKRHYALPFPAAGEATA
HHHHHCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]